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Should oral combination therapy be the standard of care for pulmonary arterial hypertension?.

Expert review of respiratory medicine

Ogawa A, Matsubara H.
PMID: 31983257
Expert Rev Respir Med. 2020 Apr;14(4):341-343. doi: 10.1080/17476348.2020.1722641. Epub 2020 Jan 28.

No abstract available.

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Ogawa A, Matsubara H. Should oral combination therapy be the standard of care for pulmonary arterial hypertension?. Expert Rev Respir Med. 2020;14(4):341-343doi: 10.1080/17476348.2020.1722641.
Ogawa, A., & Matsubara, H. (2020). Should oral combination therapy be the standard of care for pulmonary arterial hypertension?. Expert review of respiratory medicine, 14(4), 341-343. https://doi.org/10.1080/17476348.2020.1722641
Ogawa, Aiko, and Matsubara, Hiromi. "Should oral combination therapy be the standard of care for pulmonary arterial hypertension?." Expert review of respiratory medicine vol. 14,4 (2020): 341-343. doi: https://doi.org/10.1080/17476348.2020.1722641
Ogawa A, Matsubara H. Should oral combination therapy be the standard of care for pulmonary arterial hypertension?. Expert Rev Respir Med. 2020 Apr;14(4):341-343. doi: 10.1080/17476348.2020.1722641. Epub 2020 Jan 28. PMID: 31983257.
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Epoprostenol Delivered via High Flow Nasal Cannula for ICU Subjects with Severe Hypoxemia Comorbid with Pulmonary Hypertension or Right Heart Dysfunction.

Pharmaceutics

Li J, Harnois LJ, Markos B, Roberts KM, Homoud SA, Liu J, Mirza S, Vines D.
PMID: 31207936
Pharmaceutics. 2019 Jun 14;11(6). doi: 10.3390/pharmaceutics11060281.

Inhaled epoprostenol (iEPO) has been utilized to improve oxygenation in mechanically ventilated subjects with severe hypoxemia, but the evidence for iEPO via high-flow nasal cannula (HFNC) is rare. Following approval by the institutional review board, this retrospective cohort study...

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Li J, Harnois LJ, Markos B, et al. Epoprostenol Delivered via High Flow Nasal Cannula for ICU Subjects with Severe Hypoxemia Comorbid with Pulmonary Hypertension or Right Heart Dysfunction. Pharmaceutics. 2019;11(6)doi: 10.3390/pharmaceutics11060281.
Li, J., Harnois, L. J., Markos, B., Roberts, K. M., Homoud, S. A., Liu, J., Mirza, S., & Vines, D. (2019). Epoprostenol Delivered via High Flow Nasal Cannula for ICU Subjects with Severe Hypoxemia Comorbid with Pulmonary Hypertension or Right Heart Dysfunction. Pharmaceutics, 11(6), . https://doi.org/10.3390/pharmaceutics11060281
Li, Jie, et al. "Epoprostenol Delivered via High Flow Nasal Cannula for ICU Subjects with Severe Hypoxemia Comorbid with Pulmonary Hypertension or Right Heart Dysfunction." Pharmaceutics vol. 11,6 (2019). doi: https://doi.org/10.3390/pharmaceutics11060281
Li J, Harnois LJ, Markos B, Roberts KM, Homoud SA, Liu J, Mirza S, Vines D. Epoprostenol Delivered via High Flow Nasal Cannula for ICU Subjects with Severe Hypoxemia Comorbid with Pulmonary Hypertension or Right Heart Dysfunction. Pharmaceutics. 2019 Jun 14;11(6). doi: 10.3390/pharmaceutics11060281. PMID: 31207936; PMCID: PMC6631264.
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Data mining methodology for response to hypertension symptomology-application to COVID-19-related pharmacovigilance.

eLife

Xu X, Kawakami J, Millagaha Gedara NI, Riviere JE, Meyer E, Wyckoff GJ, Jaberi-Douraki M.
PMID: 34812146
Elife. 2021 Nov 23;10. doi: 10.7554/eLife.70734.

BACKGROUND: Potential therapy and confounding factors including typical co-administered medications, patient's disease states, disease prevalence, patient demographics, medical histories, and reasons for prescribing a drug often are incomplete, conflicting, missing, or uncharacterized in spontaneous adverse drug event (ADE) reporting...

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Xu X, Kawakami J, Millagaha Gedara NI, et al. Data mining methodology for response to hypertension symptomology-application to COVID-19-related pharmacovigilance. Elife. 2021;10doi: 10.7554/eLife.70734.
Xu, X., Kawakami, J., Millagaha Gedara, N. I., Riviere, J. E., Meyer, E., Wyckoff, G. J., & Jaberi-Douraki, M. (2021). Data mining methodology for response to hypertension symptomology-application to COVID-19-related pharmacovigilance. eLife, 10. https://doi.org/10.7554/eLife.70734
Xu, Xuan, et al. "Data mining methodology for response to hypertension symptomology-application to COVID-19-related pharmacovigilance." eLife vol. 10 (2021). doi: https://doi.org/10.7554/eLife.70734
Xu X, Kawakami J, Millagaha Gedara NI, Riviere JE, Meyer E, Wyckoff GJ, Jaberi-Douraki M. Data mining methodology for response to hypertension symptomology-application to COVID-19-related pharmacovigilance. Elife. 2021 Nov 23;10. doi: 10.7554/eLife.70734. PMID: 34812146; PMCID: PMC8754433.
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Red Blood Cell Exchange in a Patient With Extramedullary Hematopoiesis and Cor Pulmonale Secondary to Beta Thalassemia.

Cureus

Kopparthy P, Kelkar AH, Aggarwal K, De Filippis S, Fletcher B.
PMID: 33824791
Cureus. 2021 Mar 01;13(3):e13638. doi: 10.7759/cureus.13638.

RATIONALE: Beta thalassemia is a congenital defect in the production of the beta globin chain. Patients with beta thalassemia major will have higher levels of hemoglobin F (HbF), which is suboptimal in releasing oxygen to tissue. Herein, we describe...

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Kopparthy P, Kelkar AH, Aggarwal K, et al. Red Blood Cell Exchange in a Patient With Extramedullary Hematopoiesis and Cor Pulmonale Secondary to Beta Thalassemia. Cureus. 2021;13(3):e13638doi: 10.7759/cureus.13638.
Kopparthy, P., Kelkar, A. H., Aggarwal, K., De Filippis, S., & Fletcher, B. (2021). Red Blood Cell Exchange in a Patient With Extramedullary Hematopoiesis and Cor Pulmonale Secondary to Beta Thalassemia. Cureus, 13(3), e13638. https://doi.org/10.7759/cureus.13638
Kopparthy, Pallavi, et al. "Red Blood Cell Exchange in a Patient With Extramedullary Hematopoiesis and Cor Pulmonale Secondary to Beta Thalassemia." Cureus vol. 13,3 (2021): e13638. doi: https://doi.org/10.7759/cureus.13638
Kopparthy P, Kelkar AH, Aggarwal K, De Filippis S, Fletcher B. Red Blood Cell Exchange in a Patient With Extramedullary Hematopoiesis and Cor Pulmonale Secondary to Beta Thalassemia. Cureus. 2021 Mar 01;13(3):e13638. doi: 10.7759/cureus.13638. PMID: 33824791; PMCID: PMC8011980.
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Severe thrombocytopenia in patients with idiopathic pulmonary arterial hypertension provided several strategies for lung transplantation.

Pulmonary circulation

Kobayashi T, Shigeta A, Terada J, Tanabe N, Sugiura T, Sakao S, Taniguchi K, Oto T, Tatsumi K.
PMID: 33282197
Pulm Circ. 2020 Nov 20;10(4):2045894020969103. doi: 10.1177/2045894020969103. eCollection 2020.

While the prognosis of idiopathic pulmonary arterial hypertension has improved significantly due to newer medications, lung transplantation remains a critical therapeutic option for severe pulmonary arterial hypertension. Hence, it is essential for patients awaiting lung transplantation to avoid complications,...

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Kobayashi T, Shigeta A, Terada J, et al. Severe thrombocytopenia in patients with idiopathic pulmonary arterial hypertension provided several strategies for lung transplantation. Pulm Circ. 2020;10(4):2045894020969103doi: 10.1177/2045894020969103.
Kobayashi, T., Shigeta, A., Terada, J., Tanabe, N., Sugiura, T., Sakao, S., Taniguchi, K., Oto, T., & Tatsumi, K. (2020). Severe thrombocytopenia in patients with idiopathic pulmonary arterial hypertension provided several strategies for lung transplantation. Pulmonary circulation, 10(4), 2045894020969103. https://doi.org/10.1177/2045894020969103
Kobayashi, Takayuki, et al. "Severe thrombocytopenia in patients with idiopathic pulmonary arterial hypertension provided several strategies for lung transplantation." Pulmonary circulation vol. 10,4 (2020): 2045894020969103. doi: https://doi.org/10.1177/2045894020969103
Kobayashi T, Shigeta A, Terada J, Tanabe N, Sugiura T, Sakao S, Taniguchi K, Oto T, Tatsumi K. Severe thrombocytopenia in patients with idiopathic pulmonary arterial hypertension provided several strategies for lung transplantation. Pulm Circ. 2020 Nov 20;10(4):2045894020969103. doi: 10.1177/2045894020969103. eCollection 2020. PMID: 33282197; PMCID: PMC7686618.
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Prostacyclin Analogues Inhibit Platelet Reactivity, Extracellular Vesicle Release and Thrombus Formation in Patients with Pulmonary Arterial Hypertension.

Journal of clinical medicine

Gąsecka A, Banaszkiewicz M, Nieuwland R, van der Pol E, Hajji N, Mutwil H, Rogula S, Rutkowska W, Pluta K, Eyileten C, Postuła M, Darocha S, Huczek Z, Opolski G, Filipiak KJ, Torbicki A, Kurzyna M.
PMID: 33801460
J Clin Med. 2021 Mar 02;10(5). doi: 10.3390/jcm10051024.

(1) Background: Prostacyclin analogues (epoprostenol, treprostinil, and iloprost) induce vasodilation in pulmonary arterial hypertension (PAH) but also inhibit platelet function. (2) Objectives: We assessed platelet function in PAH patients treated with prostacyclin analogues and not receiving prostacyclin analogues. (3)...

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Gąsecka A, Banaszkiewicz M, Nieuwland R, et al. Prostacyclin Analogues Inhibit Platelet Reactivity, Extracellular Vesicle Release and Thrombus Formation in Patients with Pulmonary Arterial Hypertension. J Clin Med. 2021;10(5)doi: 10.3390/jcm10051024.
Gąsecka, A., Banaszkiewicz, M., Nieuwland, R., van der Pol, E., Hajji, N., Mutwil, H., Rogula, S., Rutkowska, W., Pluta, K., Eyileten, C., Postuła, M., Darocha, S., Huczek, Z., Opolski, G., Filipiak, K. J., Torbicki, A., & Kurzyna, M. (2021). Prostacyclin Analogues Inhibit Platelet Reactivity, Extracellular Vesicle Release and Thrombus Formation in Patients with Pulmonary Arterial Hypertension. Journal of clinical medicine, 10(5), . https://doi.org/10.3390/jcm10051024
Gąsecka, Aleksandra, et al. "Prostacyclin Analogues Inhibit Platelet Reactivity, Extracellular Vesicle Release and Thrombus Formation in Patients with Pulmonary Arterial Hypertension." Journal of clinical medicine vol. 10,5 (2021). doi: https://doi.org/10.3390/jcm10051024
Gąsecka A, Banaszkiewicz M, Nieuwland R, van der Pol E, Hajji N, Mutwil H, Rogula S, Rutkowska W, Pluta K, Eyileten C, Postuła M, Darocha S, Huczek Z, Opolski G, Filipiak KJ, Torbicki A, Kurzyna M. Prostacyclin Analogues Inhibit Platelet Reactivity, Extracellular Vesicle Release and Thrombus Formation in Patients with Pulmonary Arterial Hypertension. J Clin Med. 2021 Mar 02;10(5). doi: 10.3390/jcm10051024. PMID: 33801460; PMCID: PMC7958838.
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Feasibility of Converting Inhaled Epoprostenol Product From Flolan to Veletri in Critically Ill Patients.

American journal of therapeutics

Torbic H, Bauer SR, Wanek MR.
PMID: 33021539
Am J Ther. 2020 Oct 01;28(6):e781-e785. doi: 10.1097/MJT.0000000000001142.

No abstract available.

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Torbic H, Bauer SR, Wanek MR. Feasibility of Converting Inhaled Epoprostenol Product From Flolan to Veletri in Critically Ill Patients. Am J Ther. 2020;28(6):e781-e785doi: 10.1097/MJT.0000000000001142.
Torbic, H., Bauer, S. R., & Wanek, M. R. (2020). Feasibility of Converting Inhaled Epoprostenol Product From Flolan to Veletri in Critically Ill Patients. American journal of therapeutics, 28(6), e781-e785. https://doi.org/10.1097/MJT.0000000000001142
Torbic, Heather, et al. "Feasibility of Converting Inhaled Epoprostenol Product From Flolan to Veletri in Critically Ill Patients." American journal of therapeutics vol. 28,6 (2020): e781-e785. doi: https://doi.org/10.1097/MJT.0000000000001142
Torbic H, Bauer SR, Wanek MR. Feasibility of Converting Inhaled Epoprostenol Product From Flolan to Veletri in Critically Ill Patients. Am J Ther. 2020 Oct 01;28(6):e781-e785. doi: 10.1097/MJT.0000000000001142. PMID: 33021539.
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A Review of Pulmonary Arterial Hypertension Treatment in Extracorporeal Membrane Oxygenation: A Case Series of Adult Patients.

Journal of cardiovascular pharmacology and therapeutics

Torbic H, Hohlfelder B, Krishnan S, Tonelli AR.
PMID: 35006031
J Cardiovasc Pharmacol Ther. 2022 Jan-Dec;27:10742484211069005. doi: 10.1177/10742484211069005.

BACKGROUND: Little data is published describing the use of medications prescribed for pulmonary arterial hypertension (PAH) in patients receiving extracorporeal membrane oxygenation (ECMO). Even though many patients with PAH may require ECMO as a bridge to transplant or recovery,...

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Torbic H, Hohlfelder B, Krishnan S, et al. A Review of Pulmonary Arterial Hypertension Treatment in Extracorporeal Membrane Oxygenation: A Case Series of Adult Patients. J Cardiovasc Pharmacol Ther. 2022;27:10742484211069005doi: 10.1177/10742484211069005.
Torbic, H., Hohlfelder, B., Krishnan, S., & Tonelli, A. R. (2022). A Review of Pulmonary Arterial Hypertension Treatment in Extracorporeal Membrane Oxygenation: A Case Series of Adult Patients. Journal of cardiovascular pharmacology and therapeutics, 2710742484211069005. https://doi.org/10.1177/10742484211069005
Torbic, Heather, et al. "A Review of Pulmonary Arterial Hypertension Treatment in Extracorporeal Membrane Oxygenation: A Case Series of Adult Patients." Journal of cardiovascular pharmacology and therapeutics vol. 27 (2022): 10742484211069005. doi: https://doi.org/10.1177/10742484211069005
Torbic H, Hohlfelder B, Krishnan S, Tonelli AR. A Review of Pulmonary Arterial Hypertension Treatment in Extracorporeal Membrane Oxygenation: A Case Series of Adult Patients. J Cardiovasc Pharmacol Ther. 2022 Jan-Dec;27:10742484211069005. doi: 10.1177/10742484211069005. PMID: 35006031.
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Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial.

JAMA surgery

Ghadimi K, Cappiello J, Cooter-Wright M, Haney JC, Reynolds JM, Bottiger BA, Klapper JA, Levy JH, Hartwig MG.
PMID: 34787647
JAMA Surg. 2022 Jan 01;157(1):e215856. doi: 10.1001/jamasurg.2021.5856. Epub 2022 Jan 12.

IMPORTANCE: Inhaled nitric oxide (iNO) is commonly administered for selectively inhaled pulmonary vasodilation and prevention of oxidative injury after lung transplant (LT). Inhaled epoprostenol (iEPO) has been introduced worldwide as a cost-saving alternative to iNO without high-grade evidence for...

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Ghadimi K, Cappiello J, Cooter-Wright M, et al. Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial. JAMA Surg. 2022;157(1):e215856doi: 10.1001/jamasurg.2021.5856.
Ghadimi, K., Cappiello, J., Cooter-Wright, M., Haney, J. C., Reynolds, J. M., Bottiger, B. A., Klapper, J. A., Levy, J. H., Hartwig, M. G. (2022). Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial. JAMA surgery, 157(1), e215856. https://doi.org/10.1001/jamasurg.2021.5856
Ghadimi, Kamrouz, et al. "Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial." JAMA surgery vol. 157,1 (2022): e215856. doi: https://doi.org/10.1001/jamasurg.2021.5856
Ghadimi K, Cappiello J, Cooter-Wright M, Haney JC, Reynolds JM, Bottiger BA, Klapper JA, Levy JH, Hartwig MG. Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial. JAMA Surg. 2022 Jan 01;157(1):e215856. doi: 10.1001/jamasurg.2021.5856. Epub 2022 Jan 12. PMID: 34787647; PMCID: PMC8600451.
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Hand Impairment in Systemic Sclerosis: Various Manifestations and Currently Available Treatment.

Current treatment options in rheumatology

Young A, Namas R, Dodge C, Khanna D.
PMID: 28018840
Curr Treatm Opt Rheumatol. 2016 Sep;2(3):252-269. doi: 10.1007/s40674-016-0052-9. Epub 2016 Jul 19.

Systemic sclerosis (SSc) is an autoimmune disease initially recognized by hand involvement due to characteristic Raynaud's phenomenon (RP), puffy hands, skin thickening, and contractures resembling claw deformities. SSc contributes to hand impairment through inflammatory arthritis, joint contractures, tendon friction...

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Young A, Namas R, Dodge C, et al. Hand Impairment in Systemic Sclerosis: Various Manifestations and Currently Available Treatment. Curr Treatm Opt Rheumatol. 2016;2(3):252-269doi: 10.1007/s40674-016-0052-9.
Young, A., Namas, R., Dodge, C., & Khanna, D. (2016). Hand Impairment in Systemic Sclerosis: Various Manifestations and Currently Available Treatment. Current treatment options in rheumatology, 2(3), 252-269. https://doi.org/10.1007/s40674-016-0052-9
Young, Amber, et al. "Hand Impairment in Systemic Sclerosis: Various Manifestations and Currently Available Treatment." Current treatment options in rheumatology vol. 2,3 (2016): 252-269. doi: https://doi.org/10.1007/s40674-016-0052-9
Young A, Namas R, Dodge C, Khanna D. Hand Impairment in Systemic Sclerosis: Various Manifestations and Currently Available Treatment. Curr Treatm Opt Rheumatol. 2016 Sep;2(3):252-269. doi: 10.1007/s40674-016-0052-9. Epub 2016 Jul 19. PMID: 28018840; PMCID: PMC5176259.
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Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?.

Respiratory medicine case reports

Paciocco G, Lombi A, Vincenzi A, Pesci A, Achilli F.
PMID: 28018850
Respir Med Case Rep. 2016 Nov 24;20:59-60. doi: 10.1016/j.rmcr.2016.11.011. eCollection 2017.

We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex. Due to the severity...

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Paciocco G, Lombi A, Vincenzi A, et al. Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?. Respir Med Case Rep. 2016;20:59-60doi: 10.1016/j.rmcr.2016.11.011.
Paciocco, G., Lombi, A., Vincenzi, A., Pesci, A., & Achilli, F. (2017). Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?. Respiratory medicine case reports, 2059-60. https://doi.org/10.1016/j.rmcr.2016.11.011
Paciocco, Giuseppe, et al. "Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?." Respiratory medicine case reports vol. 20 (2017): 59-60. doi: https://doi.org/10.1016/j.rmcr.2016.11.011
Paciocco G, Lombi A, Vincenzi A, Pesci A, Achilli F. Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?. Respir Med Case Rep. 2016 Nov 24;20:59-60. doi: 10.1016/j.rmcr.2016.11.011. eCollection 2017. PMID: 28018850; PMCID: PMC5167241.
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Pulmonary hypertension secondary to pulmonary veno-occlusive disease complicated by right heart failure, hypotension and acute kidney injury.

Respiratory medicine case reports

Golzy N, Fernandes S, Sharim J, Tank R, Tazelaar HD, Epstein HE, Tapson V, Hage A.
PMID: 27872804
Respir Med Case Rep. 2016 Sep 27;20:10-13. doi: 10.1016/j.rmcr.2016.09.005. eCollection 2017.

Pulmonary veno-occlusive disease (PVOD) is rare condition which can lead to severe pulmonary hypertension, right ventricular dysfunction, and cardiopulmonary failure. The diagnosis of PVOD can be challenging due to its nonspecific symptoms and its similarity to idiopathic pulmonary arterial...

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Golzy N, Fernandes S, Sharim J, et al. Pulmonary hypertension secondary to pulmonary veno-occlusive disease complicated by right heart failure, hypotension and acute kidney injury. Respir Med Case Rep. 2016;20:10-13doi: 10.1016/j.rmcr.2016.09.005.
Golzy, N., Fernandes, S., Sharim, J., Tank, R., Tazelaar, H. D., Epstein, H. E., Tapson, V., & Hage, A. (2017). Pulmonary hypertension secondary to pulmonary veno-occlusive disease complicated by right heart failure, hypotension and acute kidney injury. Respiratory medicine case reports, 2010-13. https://doi.org/10.1016/j.rmcr.2016.09.005
Golzy, Nima, et al. "Pulmonary hypertension secondary to pulmonary veno-occlusive disease complicated by right heart failure, hypotension and acute kidney injury." Respiratory medicine case reports vol. 20 (2017): 10-13. doi: https://doi.org/10.1016/j.rmcr.2016.09.005
Golzy N, Fernandes S, Sharim J, Tank R, Tazelaar HD, Epstein HE, Tapson V, Hage A. Pulmonary hypertension secondary to pulmonary veno-occlusive disease complicated by right heart failure, hypotension and acute kidney injury. Respir Med Case Rep. 2016 Sep 27;20:10-13. doi: 10.1016/j.rmcr.2016.09.005. eCollection 2017. PMID: 27872804; PMCID: PMC5107730.
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Showing 13 to 24 of 130 entries