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Showing 3769 to 3774 of 3774 entries
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Hepatitis C virus DNA vaccines: a systematic review.

Virology journal

Shayeghpour A, Kianfar R, Hosseini P, Ajorloo M, Aghajanian S, Hedayat Yaghoobi M, Hashempour T, Mozhgani SH.
PMID: 34903252
Virol J. 2021 Dec 13;18(1):248. doi: 10.1186/s12985-021-01716-8.

BACKGROUND: Vaccination against HCV is an effective measure in reduction of virus-related public health burden and mortality. However, no prophylactic vaccine is available as of yet. DNA-based immunization is a promising modality to generate cellular and humoral immune responses....

Second-line treatment after docetaxel, cisplatin and 5-fluorouracil in metastatic squamous cell carcinomas of the anus. Pooled analysis of prospective Epitopes-HPV01 and Epitopes-HPV02 studies.

European journal of cancer (Oxford, England : 1990)

Stouvenot M, Meurisse A, Saint A, Buecher B, André T, Samalin E, Jary M, El Hajbi F, Baba-Hamed N, Pernot S, Kaminsky MC, Bouché O, Desrame J, Zoubir M, Smith D, Ghiringhelli F, Parzy A, de la Fouchardiere C, Almotlak H, Vienot A, Jacquin M, Taieb J, Nguyen T, Vernerey D, Borg C, Kim S.
PMID: 34995900
Eur J Cancer. 2022 Jan 04;162:138-147. doi: 10.1016/j.ejca.2021.11.019. Epub 2022 Jan 04.

BACKGROUND: Squamous cell carcinoma of the anus (SCCA) is a rare disease often diagnosed at a localised stage. For locally advanced recurrence or metastatic disease, DCF (docetaxel, cisplatin, 5-fluorouracil) demonstrated high efficacy and became one of the standard regimens....

Identification of CD105+ Extracellular Vesicles as a Candidate Biomarker for Metastatic Breast Cancer.

The Journal of surgical research

Douglas SR, Yeung KT, Yang J, Blair SL, Cohen O, Eliceiri BP.
PMID: 34314883
J Surg Res. 2021 Dec;268:168-173. doi: 10.1016/j.jss.2021.06.050. Epub 2021 Jul 24.

BACKGROUND: Extracellular vehicles (EVs) released by malignant tumor cells can mediate the immune response and promote metastasis through intercellular communication. EV analysis is an emerging cancer surveillance tool with advantages over traditional liquid biopsy methods. The aim of this...

CD8+ T-Cell Responses in COVID-19 Convalescent Individuals Target Conserved Epitopes From Multiple Prominent SARS-CoV-2 Circulating Variants.

Open forum infectious diseases

Redd AD, Nardin A, Kared H, Bloch EM, Pekosz A, Laeyendecker O, Abel B, Fehlings M, Quinn TC, Tobian AAR.
PMID: 34322559
Open Forum Infect Dis. 2021 Mar 30;8(7):ofab143. doi: 10.1093/ofid/ofab143. eCollection 2021 Jul.

This study examined whether CD8+ T-cell responses from coronavirus disease 2019 convalescent individuals (n = 30) potentially maintain recognition of the major severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants (alpha, beta, gamma; n = 45 mutations assessed). Only...

Identification of Novel, Immunogenic HLA-DR-Presented Prevotella copri Peptides in Patients With Rheumatoid Arthritis.

Arthritis & rheumatology (Hoboken, N.J.)

Pianta A, Chiumento G, Ramsden K, Wang Q, Strle K, Arvikar S, Costello CE, Steere AC.
PMID: 34042327
Arthritis Rheumatol. 2021 Dec;73(12):2200-2205. doi: 10.1002/art.41807. Epub 2021 Oct 22.

OBJECTIVE: We previously identified HLA-DR-presented epitopes from a 27-kd protein of Prevotella copri (Pc) obtained from peripheral blood mononuclear cells (PBMCs) from 1 rheumatoid arthritis (RA) patient. Herein, we sought to identify other HLA-DR-presented Pc peptides and source proteins...

CAREER: Ligand-induced Folding in Peptides for Biosensing Applications.

[No authors listed]
UIID-NSF: 454

In this project, funded by the Chemical Measurement and Imaging program of the Division of Chemistry and the EPSCoR office, Professor Lai from University of Nebraska at Lincoln proposes to develop a potentially generalizable peptide-based electrochemical biosensing platform for...

Showing 3769 to 3774 of 3774 entries