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Showing 1597 to 1608 of 1616 entries
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The effect of chemicals on the activity of deglycosylated Aureobasidiumβ-fructofuranosidases.

Letters in applied microbiology

Hayashi S, Tubouchi M, Takasaki Y, Imada K.
PMID: 34892916
Lett Appl Microbiol. 1994 Feb;18(2):105-106. doi: 10.1111/j.1472-765X.1994.tb00817.x.

The effects of chemicals such as metal ions and typical organic enzyme inhibitors on the activity of deglycosylated β-fructofuranosidases (P-1 and P-2) from Aureobasidium were observed and compared with those of native enzymes. P-1 and P-2 enzymes became sensitive...

Impact of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on in-hospital mortality in COVID-19 patients: ​a systematic review and meta-analysis.

Singapore medical journal

Cai XJ, Tay JCK, Kui SL, Tin AS, Tan VH.
PMID: 33256355
Singapore Med J. 2020 Nov 30; doi: 10.11622/smedj.2020159. Epub 2020 Nov 30.

INTRODUCTION: There are concerns that angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) may worsen outcomes in patients with coronavirus disease 2019 (COVID-19). This systemic review and meta-analysis aimed to study in-hospital mortality in COVID-19 patients who were...

The role of renin angiotensin system in the pathophysiology of rheumatoid arthritis.

Molecular biology reports

Moreira FRC, de Oliveira TA, Ramos NE, Abreu MAD, Simões E Silva AC.
PMID: 34417705
Mol Biol Rep. 2021 Sep;48(9):6619-6629. doi: 10.1007/s11033-021-06672-8. Epub 2021 Aug 20.

BACKGROUND: In rheumatoid arthritis (RA) and osteoarthritis (OA), chronic inflammatory processes lead to progresive joint destruction. The renin-angiotensin system (RAS) is involved in the pathogenesis of RA and OA. The aim of this mini-review article is to summarize evidence...

Deregulation of Lipid Metabolism: The Critical Factors in Ovarian Cancer.

Frontiers in oncology

Ji Z, Shen Y, Feng X, Kong Y, Shao Y, Meng J, Zhang X, Yang G.
PMID: 33194756
Front Oncol. 2020 Oct 19;10:593017. doi: 10.3389/fonc.2020.593017. eCollection 2020.

Ovarian cancer is one of the most malignant gynecological cancers around the world. In spite of multiple treatment options, the five-year survival rate is still very low. Several metabolism alterations are described as a hallmark in cancers, but alterations...

Association between Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Lung Cancer.

Southern medical journal

Helgeson SA, Waddle MR, Burnside RC, Debella YT, Lee AS, Burger CD, Li Z, Johnson PW, Patel NM.
PMID: 34480196
South Med J. 2021 Sep;114(9):607-613. doi: 10.14423/SMJ.0000000000001293.

OBJECTIVES: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are the most commonly prescribed antihypertensives, with prior studies identifying a possible association between long-term use and increased rates of lung cancer. This study evaluated this potential association in...

Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases.

The Journal of pharmacology and experimental therapeutics

Goldstein DS, Castillo G, Sullivan P, Sharabi Y.
PMID: 34503991
J Pharmacol Exp Ther. 2021 Nov;379(3):253-259. doi: 10.1124/jpet.121.000826. Epub 2021 Sep 09.

The endogenous catecholamines dopamine (DA), norepinephrine (NE), and epinephrine (EPI) play key roles in neurobehavioral, cardiovascular, and metabolic processes; various clinical disorders; and effects of numerous drugs. Steps in intracellular catecholamine synthesis and metabolism were delineated long ago, but...

Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Mortality Among COVID-19 Patients: A Systematic Review and Meta-Analysis.

American journal of therapeutics

Kashour T, Bin Abdulhak AA, Tlayjeh H, Hassett LC, Noman A, Mohsen A, Al-Mallah MH, Tleyjeh IM.
PMID: 33201001
Am J Ther. 2020 Nov 10; doi: 10.1097/MJT.0000000000001281. Epub 2020 Nov 10.

BACKGROUND: Angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are known to increase the expression of angiotensin converting enzyme 2 receptor, which has been shown to be the receptor for the acute severe respiratory syndrome coronavirus 2...

Update Alert 8: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults.

Annals of internal medicine

Mackey K, Kansagara D, Vela K.
PMID: 33900794
Ann Intern Med. 2021 Jun;174(6):W54-W55. doi: 10.7326/L21-0223. Epub 2021 Apr 27.

No abstract available.

COVID-19 and the role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers.

Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC

St John MH, Barry AR.
PMID: 33193917
Can Pharm J (Ott). 2020 Jun 14;153(4):193-197. doi: 10.1177/1715163520929373. eCollection 2020.

No abstract available.

The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (.

Frontiers in immunology

Chowdhury A, Lewin MR, Zdenek CN, Carter R, Fry BG.
PMID: 34691069
Front Immunol. 2021 Oct 07;12:752442. doi: 10.3389/fimmu.2021.752442. eCollection 2021.

African spitting cobras are unique among cobras for their potent anticoagulant venom activity arising from strong inhibition of Factor Xa. This anticoagulant effect is exerted by venom phospholipase A

Consensus on basic conduct during the hospital admission of patients with acute heart failure.

Revista clinica espanola

Fernández Rodríguez JM, Casado J, Formiga F, González-Franco Á, Arévalo JC, Beltrán M, Cerqueiro González JM, Llàcer P, Manzano L, Morales-Rull JL, Pérez Silvestre J, Conde-Martel A.
PMID: 33998516
Rev Clin Esp (Barc). 2021 May;221(5):283-296. doi: 10.1016/j.rceng.2020.01.010. Epub 2021 Mar 27.

Acute heart failure (AHF) is a highly prevalent clinical entity in individuals older than 45 years in Spain. AHF is associated with significant morbidity and mortality and is the leading cause of hospitalisation for individuals older than 65 years...

Phytochemical Composition, Antioxidant, and Enzyme Inhibition Activities of Methanolic Extracts of Two Endemic .

Plants (Basel, Switzerland)

Saravanakumar K, Sarikurkcu C, Sahinler SS, Sarikurkcu RB, Wang MH.
PMID: 34371578
Plants (Basel). 2021 Jul 05;10(7). doi: 10.3390/plants10071373.

No abstract available.

Showing 1597 to 1608 of 1616 entries