Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 152173 to 1616 of 1616 entries
Sorted by: Best Match Show Resources per page
Angioedema associated with dipeptidyl peptidase-IV inhibitors.

Clinical and molecular allergy : CMA

Cassano N, Nettis E, Di Leo E, Ambrogio F, Vena GA, Foti C.
PMID: 34872575
Clin Mol Allergy. 2021 Dec 06;19(1):24. doi: 10.1186/s12948-021-00164-7.

BACKGROUND: Dipeptidyl peptidase-IV (DPP-IV) inhibitors, also known as gliptins, are a class of oral antidiabetic agents. Postmarketing reports have documented the occurrence of angioedema in patients treated with gliptins and it was found that these drugs increased the risk...

Angiotensin Blockade Modulates the Activity of PD1/L1 Inhibitors in Metastatic Urothelial Carcinoma.

Clinical genitourinary cancer

Jain RK, Skelton Iv WP, Pond GR, Naqvi M, Kim Y, Curran C, Freeman D, Nuzzo PV, Alaiwi SA, Nassar AH, Jain RK, Sonpavde G.
PMID: 34011489
Clin Genitourin Cancer. 2021 Dec;19(6):540-546. doi: 10.1016/j.clgc.2021.04.002. Epub 2021 Apr 20.

BACKGROUND: The renin-angiotensin system is involved in the regulation of angiogenesis and cell proliferation. Angiotensin inhibition may improve drug delivery by enhancing tumor perfusion partly by downregulating transforming growth factor (TGF)-β. Because TGF-β is associated with resistance in patients...

Angiotensin-converting enzyme inhibitors in preclinical myxomatous mitral valve disease in dogs: systematic review and meta-analysis.

The Journal of small animal practice

Donati P, Tarducci A, Zanatta R, Verdier N, Belerenian G, Cordero I, Villalta C, Franco J, Tarragona L.
PMID: 34905219
J Small Anim Pract. 2021 Dec 14; doi: 10.1111/jsap.13461. Epub 2021 Dec 14.

To determine the efficacy and adverse events of the administration of angiotensin-converting enzyme inhibitors for the management of preclinical myxomatous mitral valve disease in dogs. A comprehensive search using Pubmed/MEDLINE, LILACS and CAB abstracts databases was performed. Randomised clinical...

Designing cyclopentapeptide inhibitor as potential antiviral drug for dengue virus ns5 methyltransferase.

Bioinformation

Idrus S, Tambunan US, Zubaidi AA.
PMID: 22570514
Bioinformation. 2012;8(8):348-52. doi: 10.6026/97320630008348. Epub 2012 Apr 30.

NS5 methyltransferase (Mtase) has a crucial role in the replication of dengue virus. There are two active sites on NS5 Mtase i.e., SAM and RNA-cap binding sites. Inhibition of the NS5 Mtase activity is expected to prevent the propagation...

Effect of Mineralocorticoid Receptor Antagonism and ACE Inhibition on Angiotensin Profiles in Diabetic Kidney Disease: An Exploratory Study.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Kovarik JJ, Kaltenecker CC, Domenig O, Antlanger M, Poglitsch M, Kopecky C, Säemann MD.
PMID: 34351585
Diabetes Ther. 2021 Sep;12(9):2485-2498. doi: 10.1007/s13300-021-01118-7. Epub 2021 Aug 05.

BACKGROUND: Renin-angiotensin-aldosterone system (RAAS) blockade with angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARB) is the cornerstone of antihypertensive treatment in patients with chronic kidney disease (CKD) and diabetes mellitus. Mineralocorticoid receptor antagonists (MRA) on top of conventional...

Assessment of the phylogenetic analysis and antimicrobial, antiviral, and anticancer activities of marine endophytic Streptomyces species of the soft coral Sarcophyton convolutum.

International microbiology : the official journal of the Spanish Society for Microbiology

El-Gendy MMAA, Yahya SMM, Hamed AR, El-Bondkly AMA.
PMID: 34427819
Int Microbiol. 2022 Jan;25(1):133-152. doi: 10.1007/s10123-021-00204-x. Epub 2021 Aug 24.

In the present work, the extensive biological activities of marine endophytic Streptomyces strains isolated from marine soft coral Sarcophyton convolutum have been demonstrated. Within fifty-one Streptomyces isolates evaluated for their hydrolytic enzymes and enzyme inhibitors productivities, six isolates showed...

Supramolecular Interaction of Molecular Cage and β-Galactosidase: Application in Enzymatic Inhibition, Drug Delivery and Antimicrobial Activity.

Chembiochem : a European journal of chemical biology

Mondal A, Bhat IA, Karunakaran S, De M.
PMID: 33817948
Chembiochem. 2021 Jun 02;22(11):1955-1960. doi: 10.1002/cbic.202100008. Epub 2021 May 02.

Enzyme inhibitors play a crucial role in diagnosis of a wide spectrum of diseases related to bacterial infections. We report here the effect of a water-soluble self-assembled Pd

Increased risk of major congenital malformations in early pregnancy use of angiotensin-converting-enzyme inhibitors and angiotensin-receptor-blockers: a meta-analysis.

Diabetes/metabolism research and reviews

Fu J, Tomlinson G, Feig DS.
PMID: 33779043
Diabetes Metab Res Rev. 2021 Nov;37(8):e3453. doi: 10.1002/dmrr.3453. Epub 2021 Apr 13.

AIMS: To evaluate the risk of adverse fetal outcomes after exposure to angiotensin converting enzyme inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs) in first trimester of pregnancy, by conducting a systematic review and meta-analysis.MATERIALS AND METHODS: A systematic literature...

Showing 152173 to 1616 of 1616 entries