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Showing 25 to 36 of 451 entries
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Trial finds that omapatrilat is more effective than enalapril for reducing hypertension.

Evidence-based cardiovascular medicine

[No authors listed]
PMID: 16379910
Evid Based Cardiovasc Med. 2004 Jun;8(2):117-8; discussion 119-20. doi: 10.1016/j.ebcm.2004.03.003.

No abstract available.

Comparison of the effects of imidapril and enalapril in a prospective, multicentric randomized trial in dogs with naturally acquired heart failure.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology

Amberger C, Chetboul V, Bomassi E, Rougier S, Woehrlé F, Thoulon F.
PMID: 19083305
J Vet Cardiol. 2004 Nov;6(2):9-16. doi: 10.1016/S1760-2734(06)70053-4.

OBJECTIVE: To compare the efficacy and tolerability of the long-term administration of two different angiotensin-converting enzyme inhibitors, imidapril and enalapril, in a multicentric, prospective, randomized parallel-group scheme clinical trial in dogs with naturally acquired heart disease.ANIMALS: One hundred twenty...

Bisoprolol in the treatment of chronic heart failure: from pathophysiology to clinical pharmacology and trial results.

Therapeutics and clinical risk management

Metra M, Nodari S, Bordonali T, Milani P, Lombardi C, Bugatti S, Fontanella B, Verzura G, Danesi R, Dei Cas L.
PMID: 18472978
Ther Clin Risk Manag. 2007 Aug;3(4):569-78.

Clinical trials have consistently shown the benefits of beta-blocker treatment in patients with chronic heart failure (HF). As a result, bisoprolol, carvedilol, and metoprolol succinate are now indicated for the treatment of all patients with chronic HF who do...

The brain Renin-Angiotensin system and the regulation of prolactin secretion in female rats: influence of ovarian hormones.

Journal of neuroendocrinology

Myers LS, Steele MK.
PMID: 19210444
J Neuroendocrinol. 1989 Aug 01;1(4):299-303. doi: 10.1111/j.1365-2826.1989.tb00119.x.

Abstract This study was designed to investigate the effects of exogenous and endogenous angiotensin II (All) on prolactin release in ovariectomized rats, with and without estrogen and progesterone pretreatment. In the first series of experiments, All or vehicle was...

Treatment of Post-transplant Erythrocytosis with Enalapril.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

Akash N, Smadi I, El-Lozi M.
PMID: 18408290
Saudi J Kidney Dis Transpl. 1998 Apr-Jun;9(2):144-6.

This prospective study was carried out to estimate the efficacy and safety of Enalapril therapy in post-transplant erythrocytosis. Thirteen long-term renal allograft recipients (11 males and two females) with increased hematocrit values (>51%) and elevated red cell mass were...

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Tomillero A, Moral MA.
PMID: 20508873
Methods Find Exp Clin Pharmacol. 2010 May;32(4):247-88. doi: 10.1358/mf.2010.32.4.1507200.

O(6)-Benzylguanine; (-)-Gossypol; Abatacept, AC-2592, Adalimumab, AIDSVAX gp120 B/E, Alemtuzumab, Aliskiren fumarate, ALVAC E120TMG, Ambrisentan, Amlodipine, Anakinra, Aripiprazole, Armodafinil, Atomoxetine hydrochloride, Avotermin; Bevacizumab, BIBW-2992, Bortezomib, Bosentan, Botulinum toxin type B; Canakinumab, CAT-354, Ciclesonide, CMV gB vaccine, Corifollitropin alfa, Daptomycin, Darbepoetin...

Picture Quiz: A case of mediastinal shift.

Acute medicine

Fahim A.
PMID: 21611591
Acute Med. 2007;6(3):132-3.

An 86 year old woman with a background of hypertension and arthritis presented to our medical assessment unit with 3 weeks history of mild dyspnoea and central chest discomfort. She did not have any past history of respiratory problems....

Angiotensin Converting Enzyme Inhibitor (ACEI)-Induced Acute Renal Failure in Premature Newborns with Congenital Heart Disease.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Lee GJ, Cohen R, Chang AC, Cleary JP.
PMID: 22477817
J Pediatr Pharmacol Ther. 2010 Oct;15(4):290-6.

We report three cases of angiotensin converting enzyme inhibitor (ACEI) induced nephrotoxicity in preterm infants with congenital heart disease. Patients developed acute renal failure after starting captopril or enalapril at doses commonly prescribed for term neonates. There was no...

Incidence of adverse events with telmisartan compared with ACE inhibitors: evidence from a pooled analysis of clinical trials.

Patient preference and adherence

Mancia G, Schumacher H.
PMID: 22272064
Patient Prefer Adherence. 2012;6:1-9. doi: 10.2147/PPA.S27939. Epub 2011 Dec 23.

Telmisartan is indicated for the prevention of cardiovascular events in high-risk patients, based on comparable efficacy to the angiotensin-converting enzyme (ACE) inhibitor, ramipril, in the ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET(®)) trial. However,...

A case of mitochondrial cardiomyopathy with restrictive transmitral filling pattern.

International medical case reports journal

Otsui K, Inoue N, Tamagawa A, Onishi K.
PMID: 23754918
Int Med Case Rep J. 2012 Apr 13;5:19-22. doi: 10.2147/IMCRJ.S30336. Print 2012.

A 61-year-old diabetic woman with a mitochondrial A3243G mutation was hospitalized for evaluation of breathlessness, general fatigue, and leg edema. Chest radiography revealed cardiomegaly with massive pleural effusion. Serum lactate, pyruvate, and brain natriuretic peptide concentrations were elevated. Transthoracic...

Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice.

Journal of obesity

Coppey L, Lu B, Gerard C, Yorek MA.
PMID: 23056927
J Obes. 2012;2012:326806. doi: 10.1155/2012/326806. Epub 2012 Sep 29.

We have demonstrated that treating diet-induced obese (DIO) mice with the vasopeptidase inhibitor ilepatril improved neural function. Vasopeptidase inhibitors block angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) activity. We propose that increased activity of ACE and NEP contributes to...

Clinical trials update from the European Society of Cardiology meeting 2014: PARADIGM-HF, CONFIRM-HF, SIGNIFY, atrial fibrillation, beta-blockers and heart failure, and vagal stimulation in heart failure.

ESC heart failure

Clark AL, Pellicori P.
PMID: 28834633
ESC Heart Fail. 2014 Dec;1(2):82-86. doi: 10.1002/ehf2.12012. Epub 2014 Nov 24.

This article provides an overview of trials relevant to the pathophysiology, prevention, and treatment of heart failure, presented at the European Society of Cardiology meeting held in Barcelona in autumn 2014. Trials reported here include PARADIGM-HF (LCZ696 versus enalapril...

Showing 25 to 36 of 451 entries