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Showing 13 to 24 of 942 entries
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Delivery of cancer therapeutics using nanotechnology.

Pharmaceutics

Lim EK, Jang E, Lee K, Haam S, Huh YM.
PMID: 24300452
Pharmaceutics. 2013 May 15;5(2):294-317. doi: 10.3390/pharmaceutics5020294.

Nanoparticles have been investigated as drug carriers, because they provide a great opportunity due to their advantageous features: (i) various formulations using organic/inorganic materials, (ii) easy modification of targeting molecules, drugs or other molecules on them, (iii) effective delivery...

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Lim EK, Jang E, Lee K, et al. Delivery of cancer therapeutics using nanotechnology. Pharmaceutics. 2013;5(2):294-317doi: 10.3390/pharmaceutics5020294.
Lim, E. K., Jang, E., Lee, K., Haam, S., & Huh, Y. M. (2013). Delivery of cancer therapeutics using nanotechnology. Pharmaceutics, 5(2), 294-317. https://doi.org/10.3390/pharmaceutics5020294
Lim, Eun-Kyung, et al. "Delivery of cancer therapeutics using nanotechnology." Pharmaceutics vol. 5,2 (2013): 294-317. doi: https://doi.org/10.3390/pharmaceutics5020294
Lim EK, Jang E, Lee K, Haam S, Huh YM. Delivery of cancer therapeutics using nanotechnology. Pharmaceutics. 2013 May 15;5(2):294-317. doi: 10.3390/pharmaceutics5020294. PMID: 24300452; PMCID: PMC3834952.
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Research perspectives: gold nanoparticles in cancer theranostics.

Quantitative imaging in medicine and surgery

Li J, Gupta S, Li C.
PMID: 24404441
Quant Imaging Med Surg. 2013 Dec;3(6):284-91. doi: 10.3978/j.issn.2223-4292.2013.12.02.

High recurrence rates after surgical resection remain a formidable challenge in many cancers. Although chemo- and/or radiotherapy are often applied following surgery to prevent tumor relapse, these treatments are generally accompanied by serious side effects and challenges in their...

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Li J, Gupta S, Li C. Research perspectives: gold nanoparticles in cancer theranostics. Quant Imaging Med Surg. 2013;3(6):284-91doi: 10.3978/j.issn.2223-4292.2013.12.02.
Li, J., Gupta, S., & Li, C. (2013). Research perspectives: gold nanoparticles in cancer theranostics. Quantitative imaging in medicine and surgery, 3(6), 284-91. https://doi.org/10.3978/j.issn.2223-4292.2013.12.02
Li, Junjie, et al. "Research perspectives: gold nanoparticles in cancer theranostics." Quantitative imaging in medicine and surgery vol. 3,6 (2013): 284-91. doi: https://doi.org/10.3978/j.issn.2223-4292.2013.12.02
Li J, Gupta S, Li C. Research perspectives: gold nanoparticles in cancer theranostics. Quant Imaging Med Surg. 2013 Dec;3(6):284-91. doi: 10.3978/j.issn.2223-4292.2013.12.02. PMID: 24404441; PMCID: PMC3882802.
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Nanotechnology-based inhalation treatments for lung cancer: state of the art.

Nanotechnology, science and applications

Ahmad J, Akhter S, Rizwanullah M, Amin S, Rahman M, Ahmad MZ, Rizvi MA, Kamal MA, Ahmad FJ.
PMID: 26640374
Nanotechnol Sci Appl. 2015 Nov 19;8:55-66. doi: 10.2147/NSA.S49052. eCollection 2015.

Considering the challenges associated with conventional chemotherapy, targeted and local delivery of chemotherapeutics via nanoparticle (NP) carriers to the lungs is an emerging area of interest. Recent studies and growing clinical application in cancer nanotechnology showed the huge potential...

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Ahmad J, Akhter S, Rizwanullah M, et al. Nanotechnology-based inhalation treatments for lung cancer: state of the art. Nanotechnol Sci Appl. 2015;8:55-66doi: 10.2147/NSA.S49052.
Ahmad, J., Akhter, S., Rizwanullah, M., Amin, S., Rahman, M., Ahmad, M. Z., Rizvi, M. A., Kamal, M. A., & Ahmad, F. J. (2015). Nanotechnology-based inhalation treatments for lung cancer: state of the art. Nanotechnology, science and applications, 855-66. https://doi.org/10.2147/NSA.S49052
Ahmad, Javed, et al. "Nanotechnology-based inhalation treatments for lung cancer: state of the art." Nanotechnology, science and applications vol. 8 (2015): 55-66. doi: https://doi.org/10.2147/NSA.S49052
Ahmad J, Akhter S, Rizwanullah M, Amin S, Rahman M, Ahmad MZ, Rizvi MA, Kamal MA, Ahmad FJ. Nanotechnology-based inhalation treatments for lung cancer: state of the art. Nanotechnol Sci Appl. 2015 Nov 19;8:55-66. doi: 10.2147/NSA.S49052. eCollection 2015. PMID: 26640374; PMCID: PMC4657804.
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Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging .

Biotechnology, biotechnological equipment

Bakalova R, Lazarova D, Nikolova B, Atanasova S, Zlateva G, Zhelev Z, Aoki I.
PMID: 26019630
Biotechnol Biotechnol Equip. 2015 Jan 02;29(1):175-180. doi: 10.1080/13102818.2014.984894. Epub 2014 Nov 26.

The present study was designed to investigate whether poly-ion complex hollow vesicles (polymersomes), based on chemically modified chitosan, are appropriate for passive tumour targeting in the context of their application as drug carriers. The experiments were performed on colon...

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Bakalova R, Lazarova D, Nikolova B, et al. Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging . Biotechnol Biotechnol Equip. 2014;29(1):175-180doi: 10.1080/13102818.2014.984894.
Bakalova, R., Lazarova, D., Nikolova, B., Atanasova, S., Zlateva, G., Zhelev, Z., & Aoki, I. (2015). Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging . Biotechnology, biotechnological equipment, 29(1), 175-180. https://doi.org/10.1080/13102818.2014.984894
Bakalova, Rumiana, et al. "Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging ." Biotechnology, biotechnological equipment vol. 29,1 (2015): 175-180. doi: https://doi.org/10.1080/13102818.2014.984894
Bakalova R, Lazarova D, Nikolova B, Atanasova S, Zlateva G, Zhelev Z, Aoki I. Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging . Biotechnol Biotechnol Equip. 2015 Jan 02;29(1):175-180. doi: 10.1080/13102818.2014.984894. Epub 2014 Nov 26. PMID: 26019630; PMCID: PMC4434099.
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Molecular-Thermodynamic Modeling of Mixed Cationic/Anionic Vesicles.

Langmuir : the ACS journal of surfaces and colloids

Yuet PK, Blankschtein D.
PMID: 27682332
Langmuir. 1996 Aug 07;12(16):3802-3818. doi: 10.1021/la9600513.

Vesicles are widely used as model cells in biology and medicine and are also potentially useful as drug carriers and other industrial encapsulating devices. To facilitate the practical implementation of vesicles, as well as to gain a fundamental understanding...

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Yuet PK, Blankschtein D. Molecular-Thermodynamic Modeling of Mixed Cationic/Anionic Vesicles. Langmuir. 1996;12(16):3802-3818doi: 10.1021/la9600513.
Yuet, P. K., & Blankschtein, D. (1996). Molecular-Thermodynamic Modeling of Mixed Cationic/Anionic Vesicles. Langmuir : the ACS journal of surfaces and colloids, 12(16), 3802-3818. https://doi.org/10.1021/la9600513
Yuet, Pak K, and Blankschtein, Daniel. "Molecular-Thermodynamic Modeling of Mixed Cationic/Anionic Vesicles." Langmuir : the ACS journal of surfaces and colloids vol. 12,16 (1996): 3802-3818. doi: https://doi.org/10.1021/la9600513
Yuet PK, Blankschtein D. Molecular-Thermodynamic Modeling of Mixed Cationic/Anionic Vesicles. Langmuir. 1996 Aug 07;12(16):3802-3818. doi: 10.1021/la9600513. PMID: 27682332.
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Anticancer activity of drug-loaded calcium phosphate nanocomposites against human osteosarcoma.

Biomaterials research

Son KD, Kim YJ.
PMID: 28652927
Biomater Res. 2017 Jun 24;21:13. doi: 10.1186/s40824-017-0099-1. eCollection 2017.

BACKGROUND: Calcium phosphate (CaP) based nanoparticles are considered to be ideal drug carriers for delivery of anticancer drugs because of their excellent biocompatibility and pH responsiveness. However, CaP nanoparticles have the problems of limited drug load capacity, initial burst...

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Son KD, Kim YJ. Anticancer activity of drug-loaded calcium phosphate nanocomposites against human osteosarcoma. Biomater Res. 2017;21:13doi: 10.1186/s40824-017-0099-1.
Son, K. D., & Kim, Y. J. (2017). Anticancer activity of drug-loaded calcium phosphate nanocomposites against human osteosarcoma. Biomaterials research, 2113. https://doi.org/10.1186/s40824-017-0099-1
Son, Kyoung Dan, and Kim, Young-Jin. "Anticancer activity of drug-loaded calcium phosphate nanocomposites against human osteosarcoma." Biomaterials research vol. 21 (2017): 13. doi: https://doi.org/10.1186/s40824-017-0099-1
Son KD, Kim YJ. Anticancer activity of drug-loaded calcium phosphate nanocomposites against human osteosarcoma. Biomater Res. 2017 Jun 24;21:13. doi: 10.1186/s40824-017-0099-1. eCollection 2017. PMID: 28652927; PMCID: PMC5483309.
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Critical questions in development of targeted nanoparticle therapeutics.

Regenerative biomaterials

Korsmeyer R.
PMID: 27047683
Regen Biomater. 2016 Jun;3(2):143-7. doi: 10.1093/rb/rbw011. Epub 2016 Mar 21.

One of the fourteen Grand Challenges for Engineering articulated by the US National Academy of Engineering is 'Engineer Better Medicines'. Although there are many ways that better medicines could be engineered, one of the most promising ideas is to...

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Korsmeyer R. Critical questions in development of targeted nanoparticle therapeutics. Regen Biomater. 2016;3(2):143-7doi: 10.1093/rb/rbw011.
Korsmeyer, R. (2016). Critical questions in development of targeted nanoparticle therapeutics. Regenerative biomaterials, 3(2), 143-7. https://doi.org/10.1093/rb/rbw011
Korsmeyer, Richard. "Critical questions in development of targeted nanoparticle therapeutics." Regenerative biomaterials vol. 3,2 (2016): 143-7. doi: https://doi.org/10.1093/rb/rbw011
Korsmeyer R. Critical questions in development of targeted nanoparticle therapeutics. Regen Biomater. 2016 Jun;3(2):143-7. doi: 10.1093/rb/rbw011. Epub 2016 Mar 21. PMID: 27047683; PMCID: PMC4817320.
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Hybrid Nanostructures Containing Sulfadiazine Modified Chitosan as Antimicrobial Drug Carriers.

Nanomaterials (Basel, Switzerland)

Munteanu BS, Dumitriu RP, Profire L, Sacarescu L, Hitruc GE, Stoleru E, Dobromir M, Matricala AL, Vasile C.
PMID: 28335334
Nanomaterials (Basel). 2016 Nov 10;6(11). doi: 10.3390/nano6110207.

Chitosan (CH) nanofibrous structures containing sulfadiazine (SDZ) or sulfadiazine modified chitosan (SCH) in the form of functional nanoparticles attached to nanofibers (hybrid nanostructures) were obtained by mono-axial and coaxial electrospinning. The mono-axial design consisted of a SDZ/CH mixture solution...

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Munteanu BS, Dumitriu RP, Profire L, et al. Hybrid Nanostructures Containing Sulfadiazine Modified Chitosan as Antimicrobial Drug Carriers. Nanomaterials (Basel). 2016;6(11)doi: 10.3390/nano6110207.
Munteanu, B. S., Dumitriu, R. P., Profire, L., Sacarescu, L., Hitruc, G. E., Stoleru, E., Dobromir, M., Matricala, A. L., & Vasile, C. (2016). Hybrid Nanostructures Containing Sulfadiazine Modified Chitosan as Antimicrobial Drug Carriers. Nanomaterials (Basel, Switzerland), 6(11), . https://doi.org/10.3390/nano6110207
Munteanu, Bogdanel Silvestru, et al. "Hybrid Nanostructures Containing Sulfadiazine Modified Chitosan as Antimicrobial Drug Carriers." Nanomaterials (Basel, Switzerland) vol. 6,11 (2016). doi: https://doi.org/10.3390/nano6110207
Munteanu BS, Dumitriu RP, Profire L, Sacarescu L, Hitruc GE, Stoleru E, Dobromir M, Matricala AL, Vasile C. Hybrid Nanostructures Containing Sulfadiazine Modified Chitosan as Antimicrobial Drug Carriers. Nanomaterials (Basel). 2016 Nov 10;6(11). doi: 10.3390/nano6110207. PMID: 28335334; PMCID: PMC5245742.
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Enzymatically active biomimetic micropropellers for the penetration of mucin gels.

Science advances

Walker D, Käsdorf BT, Jeong HH, Lieleg O, Fischer P.
PMID: 26824056
Sci Adv. 2015 Dec 11;1(11):e1500501. doi: 10.1126/sciadv.1500501. eCollection 2015 Dec.

In the body, mucus provides an important defense mechanism by limiting the penetration of pathogens. It is therefore also a major obstacle for the efficient delivery of particle-based drug carriers. The acidic stomach lining in particular is difficult to...

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Walker D, Käsdorf BT, Jeong HH, et al. Enzymatically active biomimetic micropropellers for the penetration of mucin gels. Sci Adv. 2015;1(11):e1500501doi: 10.1126/sciadv.1500501.
Walker, D., Käsdorf, B. T., Jeong, H. H., Lieleg, O., & Fischer, P. (2015). Enzymatically active biomimetic micropropellers for the penetration of mucin gels. Science advances, 1(11), e1500501. https://doi.org/10.1126/sciadv.1500501
Walker, Debora, et al. "Enzymatically active biomimetic micropropellers for the penetration of mucin gels." Science advances vol. 1,11 (2015): e1500501. doi: https://doi.org/10.1126/sciadv.1500501
Walker D, Käsdorf BT, Jeong HH, Lieleg O, Fischer P. Enzymatically active biomimetic micropropellers for the penetration of mucin gels. Sci Adv. 2015 Dec 11;1(11):e1500501. doi: 10.1126/sciadv.1500501. eCollection 2015 Dec. PMID: 26824056; PMCID: PMC4730841.
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Pravastatin chitosan nanogels-loaded erythrocytes as a new delivery strategy for targeting liver cancer.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Harisa GI, Badran MM, AlQahtani SA, Alanazi FK, Attia SM.
PMID: 26903771
Saudi Pharm J. 2016 Jan;24(1):74-81. doi: 10.1016/j.jsps.2015.03.024. Epub 2015 Mar 21.

Chitosan nanogels (CNG) are developed as one of the most promising carriers for cancer targeting. However, these carriers are rapidly eliminated from circulation by reticuloendothelial system (RES), which limits their application. Therefore, erythrocytes (ER) loaded CNG as multifunctional carrier...

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Harisa GI, Badran MM, AlQahtani SA, et al. Pravastatin chitosan nanogels-loaded erythrocytes as a new delivery strategy for targeting liver cancer. Saudi Pharm J. 2015;24(1):74-81doi: 10.1016/j.jsps.2015.03.024.
Harisa, G. I., Badran, M. M., AlQahtani, S. A., Alanazi, F. K., & Attia, S. M. (2016). Pravastatin chitosan nanogels-loaded erythrocytes as a new delivery strategy for targeting liver cancer. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 24(1), 74-81. https://doi.org/10.1016/j.jsps.2015.03.024
Harisa, Gamaleldin I, et al. "Pravastatin chitosan nanogels-loaded erythrocytes as a new delivery strategy for targeting liver cancer." Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society vol. 24,1 (2016): 74-81. doi: https://doi.org/10.1016/j.jsps.2015.03.024
Harisa GI, Badran MM, AlQahtani SA, Alanazi FK, Attia SM. Pravastatin chitosan nanogels-loaded erythrocytes as a new delivery strategy for targeting liver cancer. Saudi Pharm J. 2016 Jan;24(1):74-81. doi: 10.1016/j.jsps.2015.03.024. Epub 2015 Mar 21. PMID: 26903771; PMCID: PMC4720020.
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Mesoporous silica nanoparticles in target drug delivery system: A review.

International journal of pharmaceutical investigation

Bharti C, Nagaich U, Pal AK, Gulati N.
PMID: 26258053
Int J Pharm Investig. 2015 Jul-Sep;5(3):124-33. doi: 10.4103/2230-973X.160844.

Due to lack of specification and solubility of drug molecules, patients have to take high doses of the drug to achieve the desired therapeutic effects for the treatment of diseases. To solve these problems, there are various drug carriers...

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Bharti C, Nagaich U, Pal AK, et al. Mesoporous silica nanoparticles in target drug delivery system: A review. Int J Pharm Investig. 2015;5(3):124-33doi: 10.4103/2230-973X.160844.
Bharti, C., Nagaich, U., Pal, A. K., & Gulati, N. (2015). Mesoporous silica nanoparticles in target drug delivery system: A review. International journal of pharmaceutical investigation, 5(3), 124-33. https://doi.org/10.4103/2230-973X.160844
Bharti, Charu, et al. "Mesoporous silica nanoparticles in target drug delivery system: A review." International journal of pharmaceutical investigation vol. 5,3 (2015): 124-33. doi: https://doi.org/10.4103/2230-973X.160844
Bharti C, Nagaich U, Pal AK, Gulati N. Mesoporous silica nanoparticles in target drug delivery system: A review. Int J Pharm Investig. 2015 Jul-Sep;5(3):124-33. doi: 10.4103/2230-973X.160844. PMID: 26258053; PMCID: PMC4522861.
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The Role of Polydimethylsiloxane in the Molecular Structure of Silica Xerogels Intended for Drug Carriers.

Scientia pharmaceutica

Czarnobaj K.
PMID: 26839836
Sci Pharm. 2015 Jul 01;83(3):519-34. doi: 10.3797/scipharm.1409-08. Print 2015.

The aim of this study was to prepare and examine polymer/oxide xerogels with metronidazole (MT) as delivery systems for the local application of a drug to a bone. The nanoporous SiO2-CaO and PDMS-modified SiO2-CaO xerogel materials with different amounts...

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Czarnobaj K. The Role of Polydimethylsiloxane in the Molecular Structure of Silica Xerogels Intended for Drug Carriers. Sci Pharm. 2015;83(3):519-34doi: 10.3797/scipharm.1409-08.
Czarnobaj, K. (2015). The Role of Polydimethylsiloxane in the Molecular Structure of Silica Xerogels Intended for Drug Carriers. Scientia pharmaceutica, 83(3), 519-34. https://doi.org/10.3797/scipharm.1409-08
Czarnobaj, Katarzyna. "The Role of Polydimethylsiloxane in the Molecular Structure of Silica Xerogels Intended for Drug Carriers." Scientia pharmaceutica vol. 83,3 (2015): 519-34. doi: https://doi.org/10.3797/scipharm.1409-08
Czarnobaj K. The Role of Polydimethylsiloxane in the Molecular Structure of Silica Xerogels Intended for Drug Carriers. Sci Pharm. 2015 Jul 01;83(3):519-34. doi: 10.3797/scipharm.1409-08. Print 2015. PMID: 26839836; PMCID: PMC4727759.
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Showing 13 to 24 of 942 entries