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Showing 13 to 24 of 284 entries
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Is there a role for combinations of antiplatelet agents in stroke prevention?.

Current treatment options in neurology

Schwartz NE, Albers GW.
PMID: 18173943
Curr Treat Options Neurol. 2007 Nov;9(6):442-50. doi: 10.1007/s11940-007-0045-y.

Antiplatelet medications are the agents of choice for secondary prevention of noncardioembolic ischemic strokes. Multiple clinical trials have proven their reliable albeit modest clinical benefits and relatively good safety profile. The most commonly recommended antiplatelet agents for secondary stroke...

CTAD as a universal anticoagulant.

Journal of automated methods & management in chemistry

Yokota M, Tatsumi N, Tsuda I, Nishioka T, Takubo T.
PMID: 18924886
J Autom Methods Manag Chem. 2003;25(1):17-20. doi: 10.1155/S1463924603000038.

The feasibility of CTAD (a mixture of citrate, theophylline, adenosine and dipyridamole) as a new anticoagulant for medical laboratory use was studied prospectively. Whole blood anticoagulated with CTAD exhibited results very similar to those of blood anticoagulated with EDTA...

Commentary. Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial.

Perspectives in vascular surgery and endovascular therapy

Sobel M.
PMID: 17437989
Perspect Vasc Surg Endovasc Ther. 2007 Mar;19(1):87-9. doi: 10.1177/1531003507299489.

No abstract available.

The use of 2,3-dichloro-5,6-dicyano-p-benzoquinone for the spectrophotometric determination of some cardiovascular drugs.

Talanta

Issa AS, Mahrous MS, Salam MA, Soliman N.
PMID: 18964385
Talanta. 1987 Jul;34(7):670-2. doi: 10.1016/0039-9140(87)80087-5.

Some basic cardiovascular drugs containing secondary or tertiary amino groups are determined spectrophotometrically. The method is simple and sensitive; it is based on the interaction of the drugs, as n-electron donors, with 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) as a pi-acceptor. The highly...

Trace measurement of dipyridamole by adsorptive stripping voltammetry.

Talanta

Zeng X, Lin S, Hu N.
PMID: 18965766
Talanta. 1993 Aug;40(8):1183-7. doi: 10.1016/0039-9140(93)80185-t.

A sensitive adsorptive stripping voltammetric method for trace measurement of dipyridamole in alkaline solution is described. The method is based on the adsorptive accumulation of the drug at the hanging mercury drop electrode, followed by linear sweep voltammetric determination....

The therapeutic potential of agents acting via purine receptors.

Expert opinion on investigational drugs

Appleman JR, Erion MD.
PMID: 15991954
Expert Opin Investig Drugs. 1998 Feb;7(2):225-43. doi: 10.1517/13543784.7.2.225.

A host of physiological processes associated with the cardiovascular (CV) system, central nervous system (CNS), and a variety of other organ systems and tissues are regulated by agents, primarily adenosine (ado) and adenosine triphosphate (ATP), that act via cell-surface...

Cellular mechanisms for the treatment of chronic heart failure: the nitric oxide- and adenosine-dependent pathways.

Expert opinion on emerging drugs

Minamino T, Kitakaze M.
PMID: 15989539
Expert Opin Emerg Drugs. 2002 May;7(1):99-110. doi: 10.1517/14728214.7.1.99.

Accumulated evidence suggests that several drugs proven to improve survival in patients with chronic heart failure (CHF) enhance endogenous nitric oxide (NO)- and/or adenosine-dependent pathways. Indeed, we and others have demonstrated that: i) antagonists of either renin-angiotensin-aldosterone or beta-adrenergic...

Harken caged-disc mitral valve replacement, 1969-1975: analysis of late mortality, thromboembolism, and valve failure.

Texas Heart Institute journal

Gray RJ, Czer LS, Chaux A, Sethna D, DeRobertis M, Raymond M, Matloff JM.
PMID: 15227298
Tex Heart Inst J. 1987 Dec;14(4):411-7.

We evaluated the long-term outcome of mitral valve replacement with a Harken caged-disc prosthesis for up to 11 years (range, 50 to 130 months; mean, 81 months) in 170 patients whose mean age was 55 years. The early (30-day)...

Antiplatelet agents for secondary prevention of stroke.

Current treatment options in cardiovascular medicine

Bernstein RA.
PMID: 18582411
Curr Treat Options Cardiovasc Med. 2008 Jun;10(3):223-8. doi: 10.1007/s11936-008-0024-y.

Patients with recent ischemic stroke or transient ischemic attack (TIA) face a high risk of recurrent stroke as well as an increased risk of myocardial infarction and sudden cardiac death. In the absence of a clearly established indication for...

Regional distribution of adenosine uptake in guinea-pig brain slices and the effect of some inhibitors: Evidence for nitrobenzylthioinosine-sensitive and insensitive sites?.

Neurochemistry international

Davies LP, Hambley JW.
PMID: 20493035
Neurochem Int. 1986;8(1):103-8. doi: 10.1016/0197-0186(86)90106-3.

The accumulation of [2-(3)H]adenosine was measured in slices prepared from 7 regions of the guinea-pig central nervous system. There was a similar level of uptake in forebrain regions (cerebral cortex, striatum, hippocampus and midbrain), a lower level in the...

Dipyridamole and Platelet Release of Platelet-derived Growth Factor.

Platelets

Vissinger H, Husted SE, Kristensen SD, Nielsen HK.
PMID: 21043611
Platelets. 1994;5(2):105-8. doi: 10.3109/09537109409005520.

Platelet-derived growth factor (PDGF) and β-thromboglobulin (β-TG) are released from platelet alpha-granules during platelet activation. PDGF is a potent chemoattractant and mitogen for human vascular smooth muscle cells, and may be important in the development of late restenosis following...

Dipyridamole in the Management of Severe Heparin-associated Thrombocytopenia.

Platelets

Al-Momen AK, Gader AM.
PMID: 21043885
Platelets. 1993;4(2):67-71. doi: 10.3109/09537109309013198.

Severe heparin-associated thrombocytopenia (SHAT) is a rare, life-threatening condition. The aim of this prospective pilot study was to determine the safety and efficacy of dipyridamole-heparin infusion (DHI) in the management of the condition. We studied 6 patients (4 males...

Showing 13 to 24 of 284 entries