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Showing 205 to 214 of 214 entries
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Markers for blood-brain barrier integrity: how appropriate is Evans blue in the twenty-first century and what are the alternatives?.

Frontiers in neuroscience

Saunders NR, Dziegielewska KM, Møllgård K, Habgood MD.
PMID: 26578854
Front Neurosci. 2015 Oct 29;9:385. doi: 10.3389/fnins.2015.00385. eCollection 2015.

In recent years there has been a resurgence of interest in brain barriers and various roles their intrinsic mechanisms may play in neurological disorders. Such studies require suitable models and markers to demonstrate integrity and functional changes at the...

Origins of Wetting.

Langmuir : the ACS journal of surfaces and colloids

Extrand CW.
PMID: 27459085
Langmuir. 2016 Aug 09;32(31):7697-706. doi: 10.1021/acs.langmuir.6b01935. Epub 2016 Jul 26.

This feature article provides an overview of wetting phenomena. Much of the analysis done on wetting in the last 100 years assumes that the phenomena are determined by molecular interactions within the interfacial area between the liquid and solid....

Impact of Pregnancy on Intra-Host Genetic Diversity of Influenza A Viruses in Hospitalised Women: A Retrospective Cohort Study.

Journal of clinical medicine

Destras G, Pichon M, Simon B, Valette M, Escuret V, Bolze PA, Dubernard G, Gaucherand P, Lina B, Josset L.
PMID: 31739505
J Clin Med. 2019 Nov 14;8(11). doi: 10.3390/jcm8111974.

Characterising dynamics of Influenza A Viruses (IAV) within-host evolution is an active field of research which may lead to a better understanding of viral pathogenesis. Using a pregnant mouse model, a study has recently suggested that immune modulation during...

First-In-Human Trials of GamTBvac, a Recombinant Subunit Tuberculosis Vaccine Candidate: Safety and Immunogenicity Assessment.

Vaccines

Vasina DV, Kleymenov DA, Manuylov VA, Mazunina EP, Koptev EY, Tukhovskaya EA, Murashev AN, Gintsburg AL, Gushchin VA, Tkachuk AP.
PMID: 31683812
Vaccines (Basel). 2019 Nov 01;7(4). doi: 10.3390/vaccines7040166.

Tuberculosis is known to be the biggest global health problem, causing the most deaths by a single infectious agent. Vaccine-development efforts are extremely important. This paper represents the results of the first-in-human trial of recombinant subunit tuberculosis vaccine GamTBvac...

Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics.

Molecular cancer therapeutics

Rafidi H, Estevez A, Ferl GZ, Mandikian D, Stainton S, Sermeño L, Williams SP, Kamath AV, Koerber JT, Boswell CA.
PMID: 34315765
Mol Cancer Ther. 2021 Oct;20(10):2008-2015. doi: 10.1158/1535-7163.MCT-21-0116. Epub 2021 Jul 26.

Advances in antibody engineering have enabled the construction of novel molecular formats in diverse shapes and sizes, providing new opportunities for cancer immunotherapeutic drug discovery while also revealing limitations in knowledge of structure-activity relationships. The current understanding of renal...

Antibacterial porous sponge fabricated with capric acid-grafted chitosan and oxidized dextran as a novel hemostatic dressing.

Carbohydrate polymers

Wang X, Dang Q, Liu C, Chang G, Song H, Xu Q, Ma Y, Li B, Zhang B, Cha D.
PMID: 34893218
Carbohydr Polym. 2022 Feb 01;277:118782. doi: 10.1016/j.carbpol.2021.118782. Epub 2021 Oct 19.

This work aims to fabricate multifunctional hemostatic sponges (C-ODs). Porous C-ODs were first constructed by using capric acid-modified chitosan (CSCA) and oxidized dextrans (ODs) with different oxidation degrees. Batches of experiments showed that (i) CSCA (33.39% of grafting degree),...

The Ontologies Community of Practice: A CGIAR Initiative for Big Data in Agrifood Systems.

Patterns (New York, N.Y.)

Arnaud E, Laporte MA, Kim S, Aubert C, Leonelli S, Miro B, Cooper L, Jaiswal P, Kruseman G, Shrestha R, Buttigieg PL, Mungall CJ, Pietragalla J, Agbona A, Muliro J, Detras J, Hualla V, Rathore A, Das RR, Dieng I, Bauchet G, Menda N, Pommier C, Shaw F, Lyon D, Mwanzia L, Juarez H, Bonaiuti E, Chiputwa B, Obileye O, Auzoux S, Yeumo ED, Mueller LA, Silverstein K, Lafargue A, Antezana E, Devare M, King B.
PMID: 33205138
Patterns (N Y). 2020 Sep 25;1(7):100105. doi: 10.1016/j.patter.2020.100105. eCollection 2020 Oct 09.

Heterogeneous and multidisciplinary data generated by research on sustainable global agriculture and agrifood systems requires quality data labeling or annotation in order to be interoperable. As recommended by the FAIR principles, data, labels, and metadata must use controlled vocabularies...

Durable Polyelectrolyte Microcapsules with Near-Infrared-Triggered Loading and Nondestructive Release of Cargo.

ACS applied materials & interfaces

Chojnacka-Górka K, Wolski K, Zapotoczny S.
PMID: 33369391
ACS Appl Mater Interfaces. 2021 Jan 13;13(1):1562-1572. doi: 10.1021/acsami.0c19353. Epub 2020 Dec 28.

Microcapsules formed using a "layer-by-layer" alternating deposition of oppositely charged polyelectrolytes on sacrificial templates have reached high interest because of their facile fabrication procedure using a broad range of materials and tailored properties. However, their practical applications as microcarriers...

Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis.

Cellular and molecular life sciences : CMLS

De Schutter E, Ramon J, Pfeuty B, De Tender C, Stremersch S, Raemdonck K, de Beeck KO, Declercq W, Riquet FB, Braeckmans K, Vandenabeele P.
PMID: 34971436
Cell Mol Life Sci. 2021 Dec 31;79(1):19. doi: 10.1007/s00018-021-04078-0.

Secondary necrosis has long been perceived as an uncontrolled process resulting in total lysis of the apoptotic cell. Recently, it was shown that progression of apoptosis to secondary necrosis is regulated by Gasdermin E (GSDME), which requires activation by...

Infusion efficiency of fluorescein derivatives of different molecular sizes into various starches under atmospheric and high hydrostatic pressures.

Food science and biotechnology

Kim KS, Oh SM, Choi SH, Choi JH, Bae JE, Kim HY, Ye SJ, Baik MY.
PMID: 34721929
Food Sci Biotechnol. 2021 Aug 29;30(10):1339-1346. doi: 10.1007/s10068-021-00972-2. eCollection 2021 Oct.

Fluorescein isothiocyanate-dextrans (FDs) of different molecular weights were infused into corn, waxy rice, tapioca, and potato starches under atmospheric and high hydrostatic pressures (HHP). FD4, FD10, FD20, and FD40 (Mw 4000, 10,000, 20,000, and 40,000, respectively) were used as...

Showing 205 to 214 of 214 entries