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Showing 5701 to 5708 of 5708 entries
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Rational design of mixed nanomicelle eye drops with structural integrity investigation.

Acta biomaterialia

Sun L, Zhang M, Shi Y, Fang L, Cao F.
PMID: 35032720
Acta Biomater. 2022 Jan 12; doi: 10.1016/j.actbio.2022.01.014. Epub 2022 Jan 12.

Chitosan oligosaccharide-stearic acid-Valyl-Valyl-Valine/1-2-Dioleoyl-sn-glycero-3-phosphoethanolamine (CSO-SA-VVV

Final results of a phase 1b study of isatuximab short-duration fixed-volume infusion combination therapy for relapsed/refractory multiple myeloma.

Leukemia

Usmani SZ, Karanes C, Bensinger WI, D'Souza A, Raje N, Tuchman SA, Sborov D, Laubach JP, Bianchi G, Kanagavel D, Saleem R, Dubin F, Campana F, Richardson PG.
PMID: 34050260
Leukemia. 2021 Dec;35(12):3526-3533. doi: 10.1038/s41375-021-01262-w. Epub 2021 May 28.

Part B of this phase 1b study (ClinicalTrials.gov number, NCT02283775) evaluated safety and efficacy of a fixed-volume infusion of isatuximab, an anti-CD38 monoclonal antibody, in combination with pomalidomide and dexamethasone (Pd) in relapsed/refractory multiple myeloma patients. Isatuximab (10 mg/kg...

A Case of Severe COVID-19 Pneumonia Diagnosed in Bronchoscopy With Negative Repeated Nasopharyngeal Swabs.

Journal of medical cases

Shukha Y, Makhoul K, Abu-Elhija J, Hayek T, Hamoud S.
PMID: 34429794
J Med Cases. 2021 Jun;12(6):217-219. doi: 10.14740/jmc3679. Epub 2021 Mar 24.

Coronavirus disease 2019 (COVID-19) is a worldwide pandemic that had emerged in China since December 2019. The disease affects all age groups, with clinical manifestations in the spectrum from asymptomatic to rapidly lethal multi-organ failure, mainly involving the respiratory...

Diagnosing Disseminated Nocardiosis in a Patient With COVID-19 Pneumonia.

Journal of medical cases

Atemnkeng F, Ducey J, Khalil A, Elemam A, Diaz K.
PMID: 34429798
J Med Cases. 2021 Aug;12(8):319-324. doi: 10.14740/jmc3716. Epub 2021 Jul 03.

Signs and symptoms of atypical pneumonia include fever, shortness of breath, cough, and chest pain. During the coronavirus disease 2019 (COVID-19) pandemic, identifying other causes of febrile respiratory illness in patients who tested positive for COVID-19 has been very...

Outcomes associated with tocilizumab with or without corticosteroid versus dexamethasone for treatment of patients with severe to critical COVID-19 pneumonia.

Journal of infection and public health

AlQahtani H, AlBilal S, Mahmoud E, Aldibasi O, Alharbi A, Shamas N, Alsaedy A, Owaidah K, Alqahtani FY, Aleanizy FS, Arishi H, Baharoon S, Bosaeed M.
PMID: 34883296
J Infect Public Health. 2021 Nov 24;15(1):36-41. doi: 10.1016/j.jiph.2021.11.017. Epub 2021 Nov 24.

INTRODUCTION: Immunomodulators, including dexamethasone (DEX), have been recommended by the Infectious Disease Society of America (IDSA) to treat moderate, severe, and critical COVID-19. Tocilizumab (TCZ) was added to the treatment recommendations based on recent data from two large randomized...

Ascaridia galli challenge model for worm propagation in young chickens with or without immunosuppression.

Veterinary parasitology

Feyera T, Shifaw AY, Ruhnke I, Sharpe B, Elliott T, Walkden-Brown SW.
PMID: 34883322
Vet Parasitol. 2021 Nov 26;301:109624. doi: 10.1016/j.vetpar.2021.109624. Epub 2021 Nov 26.

With the continued growth of free-range egg production, the importance of the chicken roundworm Ascaridia galli is increasing. Investigations into this parasite would be facilitated by the availability of characterised strains and clear guidelines on optimal methods of multiplication...

Critical respiratory failure in pregnancy complicated with COVID-19: A case report.

Case reports in women's health

Chinen Y, Kinjyo Y, Mekaru K, Kinjo T, Higure Y, Kinjo T, Miyagi K, Yamada H, Masamoto H, Goya H, Yoshida T, Maeshiro S, Nakamatsu M, Fujita J, Aoki Y.
PMID: 33777708
Case Rep Womens Health. 2021 Apr;30:e00309. doi: 10.1016/j.crwh.2021.e00309. Epub 2021 Mar 23.

The case is presented of a 29-year-old primiparous woman who was COVID-19-positive at 34 weeks of gestation and who developed severe acute respiratory distress syndrome. After a four-day history of fever and mild dyspnea, she was referred to hospital....

High Sensitivity of the Circadian Clock in the Hippocampal Dentate Gyrus to Glucocorticoid- and GSK3-Beta-Dependent Signals.

Neuroendocrinology

Liška K, Sládek M, Houdek P, Shrestha N, Lužná V, Ralph MR, Sumová A.
PMID: 34111876
Neuroendocrinology. 2021 Jun 10; doi: 10.1159/000517689. Epub 2021 Jun 10.

AIMS: Circadian clocks in the hippocampus (HPC) align memory processing with appropriate time of day. Our study was aimed at ascertaining the specificity of glycogen synthase kinase 3-beta (GSK3β)- and glucocorticoid (GC)-dependent pathways in the entrainment of clocks in...

Showing 5701 to 5708 of 5708 entries