Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 817 to 828 of 838 entries
Sorted by: Best Match Show Resources per page
The Relationship Between Androgens and Days per Month of Period Pain, Pelvic Pain, Headache, and TLR4 Responsiveness of Peripheral Blood Mononuclear Cells in Young Women with Dysmenorrhoea.

Journal of pain research

Evans SF, Kwok Y, Solterbeck A, Pyragius C, Hull ML, Hutchinson MR, Rolan P.
PMID: 33688248
J Pain Res. 2021 Mar 03;14:585-599. doi: 10.2147/JPR.S279253. eCollection 2021.

PURPOSE: Women bear a disproportionate burden of persistent pain conditions when compared to men. To determine whether the hormonal environment affects the clinical experience of pain, as measured by the days per month of pelvic pain (DPelvicPM), period pain...

Pediatric adrenocortical tumors cohort characteristics and long-term follow-up at a single Argentinian tertiary center.

Journal of pediatric endocrinology & metabolism : JPEM

Mattone MC, Gil S, Costanzo M, Galluzzo Mutti ML, Casanovas A, Zaidman V, Lazzati JM, Ciaccio M, Belgorosky A, Guercio G.
PMID: 34674406
J Pediatr Endocrinol Metab. 2021 Oct 22;35(1):19-27. doi: 10.1515/jpem-2021-0392. Print 2022 Jan 27.

Pediatric adrenocortical tumors are rare and heterogeneous endocrine malignancies.OBJECTIVES: To report clinical, biochemical, and histological features, staging, and therapeutic interventions in a cohort of 28 patients treated at a single tertiary center.METHODS: A retrospective review of medical records of...

The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30.

Redox biology

Li L, Wang H, Yao Y, Cao J, Jiang Z, Yan W, Chu X, Li Q, Lu M, Ma H.
PMID: 34781165
Redox Biol. 2021 Nov 12;48:102187. doi: 10.1016/j.redox.2021.102187. Epub 2021 Nov 12.

The prevalence of nonalcoholic steatohepatitis (NASH) caused by estrogen deficiency increased sharply in recent decades and has become a major threat to liver health in postmenopausal women. There is no effective strategy to control the incidence and development of...

Fenfluramine modulates the anti-amnesic effects induced by sigma-1 receptor agonists and neuro(active)steroids in vivo.

Epilepsy & behavior : E&B

Martin P, Maurice T, Gammaitoni A, Farfel G, Boyd B, Galer B.
PMID: 35007961
Epilepsy Behav. 2022 Jan 07;127:108526. doi: 10.1016/j.yebeh.2021.108526. Epub 2022 Jan 07.

Fenfluramine (N-ethyl-α-methl-3-(trifluoromethyl)phenethylamine) is an anti-seizure medication (ASM) particularly effective in patients with Dravet syndrome, a severe treatment-resistant epileptic encephalopathy. Fenfluramine acts not only as neuronal serotonin (5-HT) releaser but also as a positive modulator of the sigma-1 receptor (S1R)....

Natural disaster stress during pregnancy is linked to reprogramming of the placenta transcriptome in relation to anxiety and stress hormones in young offspring.

Molecular psychiatry

Nomura Y, Rompala G, Pritchett L, Aushev V, Chen J, Hurd YL.
PMID: 33981007
Mol Psychiatry. 2021 Nov;26(11):6520-6530. doi: 10.1038/s41380-021-01123-z. Epub 2021 May 12.

Prenatal stress can lead to long-term adverse effects that increase the risk of anxiety and other emotional disorders in offspring. The in utero underpinnings contributing to such phenotypes remain unknown. We profiled the transcriptome of placental specimens from women...

Regulations of expressions of rat/human sulfotransferases by anticancer drug, nolatrexed, and micronutrients.

Anti-cancer drugs

Maiti S, MaitiDutta S, Chen G.
PMID: 34387600
Anticancer Drugs. 2021 Aug 11; doi: 10.1097/CAD.0000000000001155. Epub 2021 Aug 11.

Cancer is related to the cellular proliferative state. Increase in cell-cycle regulatory function augments cellular folate pool. This pathway is therapeutically targeted. A number of drugs influences this metabolism, that is, folic acid, folinic acid, nolatrexed, and methotrexate. Our...

Dehydroepiandrosterone (DHEA) Serum Levels Indicate Cerebrospinal Fluid Levels of DHEA and Estradiol (E2) in Women at Term Pregnancy.

Reproductive sciences (Thousand Oaks, Calif.)

Habib P, Neulen J, Habib S, Rösing B.
PMID: 33772479
Reprod Sci. 2021 Oct;28(10):2823-2829. doi: 10.1007/s43032-021-00541-2. Epub 2021 Mar 26.

Neuroactive steroids such as dehydroepiandrosterone (DHEA), estradiol (E2), and progesterone (P4) are associated with structural and functional changes in the central nervous system (CNS). Measurement of steroid levels in the CNS compartments is restricted in accessibility. Consequently, there is...

Functional characterization of Clonorchis sinensis sodium-bile acid co-transporter (CsSBAT) as a steroid sulfate transporter.

Parasitology research

Jung H, Won JY, Park YK, Han JH, Cha SH.
PMID: 34825261
Parasitol Res. 2022 Jan;121(1):217-224. doi: 10.1007/s00436-021-07393-4. Epub 2021 Nov 26.

Clonorchis sinensis (Cs) is a common trematode in Asian countries. Infection by Cs can result in many clinical symptoms. Here, a cDNA encoding a Cs apical sodium-dependent bile acid transporter (CsSBAT) was isolated from a Cs cDNA library, and...

Diagnostic Accuracy of Dehydroepiandrosterone Sulfate and Corticotropin in Autonomous Cortisol Secretion.

Biomedicines

Carafone LE, Zhang CD, Li D, Lazik N, Hamidi O, Hurtado MD, Young WF, Thomas MA, Dy BM, Lyden ML, Foster TR, McKenzie TJ, Bancos I.
PMID: 34203283
Biomedicines. 2021 Jun 28;9(7). doi: 10.3390/biomedicines9070741.

Autonomous cortisol secretion (ACS) affects up to 50% of patients with adrenal adenomas. Despite the limited evidence, clinical guidelines recommend measurement of serum concentrations of dehydroepiandrosterone-sulfate (DHEA-S) and corticotropin (ACTH) to aid in the diagnosis of ACS. Our objective...

A Prospective Study of the Relationship Between Clinical Outcomes After Enzalutamide and Serum Androgen Levels Measured via Liquid Chromatography-tandem Mass Spectrometry in Patients with Castration-resistant Prostate Cancer.

European urology open science

Miyazawa Y, Sekine Y, Arai S, Nakamura T, Takezawa Y, Shimizu N, Matsuo Y, Ogura H, Takei T, Suzuki K.
PMID: 34337535
Eur Urol Open Sci. 2021 Jun 07;29:59-67. doi: 10.1016/j.euros.2021.05.003. eCollection 2021 Jul.

BACKGROUND: Enzalutamide (ENZ) is used to treat patients with castration-resistant prostate cancer (CRPC). However, the kinetics of serum androgens before and after ENZ treatment are unknown.OBJECTIVE: To elucidate the kinetics of serum androgens and explore the possibility of identifying...

Pre-breeding androgen and glucocorticoid profiles in the eastern hellbender salamander (Cryptobranchus alleganiensis alleganiensis).

General and comparative endocrinology

Galligan TM, Helm RF, Case BF, Bodinof Jachowski CM, Frazier CL, Alaasam V, Hopkins WA.
PMID: 34499909
Gen Comp Endocrinol. 2021 Nov 01;313:113899. doi: 10.1016/j.ygcen.2021.113899. Epub 2021 Sep 06.

Seasonally breeding species exhibit cyclical changes in circulating steroid hormone profiles that correspond with changes to their reproductive behavior and ecology. Such information is critical to the conservation of imperiled and data-deficient species, such as the eastern hellbender salamander...

Dietary supplementation of gingerols- and shogaols-enriched ginger root extract attenuate pain-associated behaviors while modulating gut microbiota and metabolites in rats with spinal nerve ligation.

The Journal of nutritional biochemistry

Shen CL, Wang R, Ji G, Elmassry MM, Zabet-Moghaddam M, Vellers H, Hamood AN, Gong X, Mirzaei P, Sang S, Neugebauer V.
PMID: 34748918
J Nutr Biochem. 2021 Nov 06;100:108904. doi: 10.1016/j.jnutbio.2021.108904. Epub 2021 Nov 06.

Neuroinflammation is a central factor in neuropathic pain (NP). Ginger is a promising bioactive compound in NP management due to its anti-inflammatory property. Emerging evidence suggests that gut microbiome and gut-derived metabolites play a key role in NP. We...

Showing 817 to 828 of 838 entries