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Showing 13 to 24 of 838 entries
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Influence of Diet and Dehydroepiandrosterone on Hypothalamic Monoamine Neurotransmitters in Zucker Rats.

Nutritional neuroscience

Svec F, Porter J.
PMID: 27415806
Nutr Neurosci. 1999;2(5):337-45. doi: 10.1080/1028415X.1999.11747288.

Food intake is controlled by hypothalamic neurotransmitters. Exogenous dehydroepiandrosterone (DHEA) decreases Zucker rat caloric intake, alters selection of macronutrients and affects the level of hypothalamic neurotransmitters. The goal of this study was to determine whether the changes induced by...

Evaluation of Dehydroepiandrosterone Supplementation on Diminished Ovarian Reserve: A Randomized, Double-Blinded, Placebo-Controlled Study.

Journal of obstetrics and gynaecology of India

Agarwal R, Shruthi R, Radhakrishnan G, Singh A.
PMID: 28405122
J Obstet Gynaecol India. 2017 Apr;67(2):137-142. doi: 10.1007/s13224-016-0941-8. Epub 2016 Sep 19.

INTRODUCTION: We conducted a randomized, double-blinded, placebo-controlled study, to evaluate the effect of dehydroepiandrosterone (DHEA), on diminished ovarian reserve (DOR).MATERIALS AND METHODS: Twenty patients with DOR received DHEA (oral 25 mg three times a day). Post-supplementation 12 weeks, D2/3...

Proinflammatory and anti-inflammatory cytokine changes related to menopause.

Przeglad menopauzalny = Menopause review

Malutan AM, Dan M, Nicolae C, Carmen M.
PMID: 26327849
Prz Menopauzalny. 2014 Jun;13(3):162-8. doi: 10.5114/pm.2014.43818. Epub 2014 Jun 30.

THE AIM OF THE STUDY: The aim of the study was to determine menopause-related changes in serum levels of main proinflammatory and anti-inflammatory cytokines.MATERIAL AND METHODS: The study included 175 women, who were divided into 5 study groups (group...

Neurosteroids in clinical practice: implications for women's health.

Hormone molecular biology and clinical investigation

Genazzani AR, Bucci F, Russo N, Daino D, Santoro AN, Pluchino N.
PMID: 25961341
Horm Mol Biol Clin Investig. 2011 Oct 01;7(3):413-23. doi: 10.1515/HMBCI.2011.120.

The steroidogenic endocrine glands and local synthesis both contribute to the pool of steroids present in the central nervous system (CNS) and peripheral nervous system (PNS). Although the synthesis of neurosteroids in the nervous system is now well established,...

Chemical and biochemical approaches to the production of 7-hydroxylated C19-steroids.

Hormone molecular biology and clinical investigation

Ferroud C, Revial G, Morfin R.
PMID: 25436687
Horm Mol Biol Clin Investig. 2012 Jun;10(3):293-9. doi: 10.1515/hmbci-2012-0013.

Abstract Interest has developed into 7-hydroxylated derivatives of 3β-hydroxylated C19-steroids, such as dehydroepiandrosterone (DHEA) and epiandrosterone because of their effects on inflammation, immune response, and cell repair. These steroids are not currently available from commercial sources, and it is...

Organic anion transporter 2 transcript variant 1 shows broad ligand selectivity when expressed in multiple cell lines.

Frontiers in pharmacology

Hotchkiss AG, Berrigan L, Pelis RM.
PMID: 26500550
Front Pharmacol. 2015 Oct 06;6:216. doi: 10.3389/fphar.2015.00216. eCollection 2015.

Organic anion transporter 2 (OAT2) is likely important for renal and hepatic drug elimination. Three variants of the OAT2 peptide sequence have been described - OAT2 transcript variant 1 (OAT2-tv1), OAT2 transcript variant 2 (OAT2-tv2), and OAT2 transcript variant...

Insulin-like growth factor-binding protein-3 is associated with the presence and extent of coronary arteriosclerosis.

Arteriosclerosis, thrombosis, and vascular biology

Schuler-Luttmann S, Monnig G, Enbergs A, Schulte H, Breithardt G, Assmann G, Kerber S, von Eckardstein A.
PMID: 10764692
Arterioscler Thromb Vasc Biol. 2000 Apr;20(4):E10-5.

Aging is associated with the progression of arteriosclerosis and the decline of several endocrine functions. We therefore investigated the association of coronary arteriosclerosis with hormones, the serum concentrations of which change during aging. Coronary angiograms of 189 men /=1...

Could hormones make a difference in the treatment of juvenile rheumatoid arthritis?.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Khalkhali-Ellis Z, Moore TL, Hendrix MJ.
PMID: 18034514
BioDrugs. 2000 Feb;13(2):77-86. doi: 10.2165/00063030-200013020-00001.

Adrenal androgens dehydroepiandrosterone (DHEA; prasterone) and its sulphated form (DHEA-S) are among the most abundant hormonal steroids in men and nonpregnant women. Deficiencies of these adrenal androgens are associated with autoimmune disorders such as rheumatoid arthritis (RA). Recent studies...

Body mass index, waist/hip ratio and androgen-estrogen activity in younger versus older Polish men.

The aging male : the official journal of the International Society for the Study of the Aging Male

Jankowska EW, Medras M, Rogucka EA.
PMID: 16760023
Aging Male. 2000 Dec;3(4):177-84. doi: 10.1080/13685530008500366.

This study was performed to evaluate the associations between estradiol, dehydroepiandrosterone sulfate (DHEAS), free and total testosterone levels, and anthropometric parameters of general adiposity (body mass index, BMI) and fat distribution (waist/hip ratio, WHR), separately in two subgroups of...

The use of steroid replacement therapy for the management of Addison's disease.

IDrugs : the investigational drugs journal

Elsheikh M, Wass JA.
PMID: 16113988
IDrugs. 1999 Nov;2(11):1165-9.

Addison's disease is an uncommon but potentially life-threatening condition characterized by adrenal failure. All patients require lifelong glucocorticoid replacement to maintain life and most also need aldosterone substitution. There has been some recent interest in the physiological role in...

Dehydroepiandrosterone supplements: bringing sense to sensational claims.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Nippoldt TB.
PMID: 15251755
Endocr Pract. 1998 Mar-Apr;4(2):106-11. doi: 10.4158/EP.4.2.106.

OBJECTIVE: To summarize the current information about dehydroepiandrosterone (DHEA), a steroid hormone produced in the adrenal cortex.METHODS: The biochemical and physiologic features of DHEA and its purported effects on overall age-related decline and on various disorders are reviewed. In...

Measuring cortisol and DHEA in fingernails: a pilot study.

Neuropsychiatric disease and treatment

Warnock F, McElwee K, Seo RJ, McIsaac S, Seim D, Ramirez-Aponte T, Macritchie KA, Young AH.
PMID: 20169040
Neuropsychiatr Dis Treat. 2010 Feb 03;6:1-7.

PURPOSE: Abnormalities in both cortisol and dehydroepiandrosterone (DHEA) have been reported in psychiatric disorders. Analysis of saliva, urine and blood cortisol and DHEA levels provides an index of hormone levels over a short time period. Unlike such conventional measures,...

Showing 13 to 24 of 838 entries