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Showing 409 to 412 of 412 entries
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Facile and foldable point-of-care biochip for nucleic acid based-colorimetric detection of murine norovirus in fecal samples using G-quadruplex and graphene oxide coated microbeads.

Biosensors & bioelectronics

Cui WY, Yoo HJ, Li YG, Baek C, Min J.
PMID: 34915211
Biosens Bioelectron. 2021 Dec 11;199:113878. doi: 10.1016/j.bios.2021.113878. Epub 2021 Dec 11.

Norovirus is one of the most common causes of gastroenteritis, a disease characterized by diarrhea, vomiting, and stomach pain. A rapid on-site identification of the virus from fecal samples of patients is a prerequisite for accurate medical management. Here,...

Molecular Beacon DNA Probes with Fluorescein Bifluorophore.

Russian journal of bioorganic chemistry

Brylev VA, Lysenko IL, Kokin EA, Martynenko-Makaev YV, Ryazantsev DY, Shmanai VV, Korshun VA.
PMID: 34149274
Russ J Bioorg Chem. 2021;47(3):734-740. doi: 10.1134/S1068162021030055. Epub 2021 Jun 11.

An azido-derivative of a fluorescein bifluorophore was obtained and used for the synthesis of "molecular beacon"-type oligonucleotide fluorogenic probes for RT-PCR. Eight probe variants were synthesized based on an optimized sequence: with one or two quencher residues at the...

What Happens When a Complementary DNA Meets miR-29a Cancer Biomarker in Complex with a Graphene Quantum Dot.

ACS applied bio materials

Kuntip N, Japrung D, Pongprayoon P.
PMID: 35005926
ACS Appl Bio Mater. 2021 Dec 20;4(12):8368-8376. doi: 10.1021/acsabm.1c00943. Epub 2021 Dec 09.

MicroRNAs (miRNAs), short single-stranded noncoding RNA molecules, serve as potential cancer biomarkers due to their involvement in cancer development. One of the strategies to extract miRNAs is to perform the miRNA adsorption on nanomaterials and dissociation by a complementary...

Automating the Design of Cancer Specific DNA Probes Using Computational Algorithms.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Zhang J, Alexandrou G, Toumazou C, Kalofonou M.
PMID: 34891648
Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:1852-1856. doi: 10.1109/EMBC46164.2021.9630589.

This paper introduces a novel Python script which automates the design process of cancer variant-specific DNA probes, based on the amplification method LAMP (Loop-Mediated Isothermal Amplification). With just an input of the DNA sequence and the mutation base location,...

Showing 409 to 412 of 412 entries