Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 13 to 24 of 313 entries
Sorted by: Best Match Show Resources per page
Cardiomyocyte gap junctions: a target of growth-promoting signaling.

Trends in cardiovascular medicine

Kardami E, Doble BW.
PMID: 21235931
Trends Cardiovasc Med. 1998 May;8(4):180-7. doi: 10.1016/S1050-1738(98)00007-3.

Gap junctions (GJ), composed of connexins, are membrane channels that connect and enable communication between neighboring cells and which, in addition to being essential for the coordinated electrical and contractile activity of the heart, may regulate intercellular transmission of...

Connexin45 is the first connexin to be expressed in the central conduction system of the mouse heart.

Experimental and clinical cardiology

Coppen SR, Gourdie RG, Severs NJ.
PMID: 20428439
Exp Clin Cardiol. 2001;6(1):17-23.

OBJECTIVE: To examine the spatial pattern of labelling for the gap junctional protein, connexin45, in relation to that of the other two cardiac connexins, connexin40 and connexin43, during the development of the central conduction system in mouse heart.ANIMALS AND...

Connexin and pannexin mediated cell-cell communication.

Neuron glia biology

Scemes E, Suadicani SO, Dahl G, Spray DC.
PMID: 18634611
Neuron Glia Biol. 2007 Aug;3(3):199-208. doi: 10.1017/S1740925X08000069.

In this review, we briefly summarize what is known about the properties of the three families of gap junction proteins, connexins, innexins and pannexins, emphasizing their importance as intercellular channels that provide ionic and metabolic coupling and as non-junctional...

Connexins, cell proliferation and second messengers in the crystalline lens.

Journal of ophthalmic & vision research

White TW.
PMID: 22737399
J Ophthalmic Vis Res. 2012 Jan;7(1):107-8.

No abstract available.

Connexin diversity in the heart: insights from transgenic mouse models.

Frontiers in pharmacology

Verheule S, Kaese S.
PMID: 23818881
Front Pharmacol. 2013 Jun 27;4:81. doi: 10.3389/fphar.2013.00081. Print 2013.

Cardiac conduction is mediated by gap junction channels that are formed by connexin (Cx) protein subunits. The connexin family of proteins consists of more than 20 members varying in their biophysical properties and ability to combine with other connexins...

Large Pore Ion and Metabolite-Permeable Channel Regulation of Postnatal Ventricular Zone Neural Stem and Progenitor Cells: Interplay between Aquaporins, Connexins, and Pannexins?.

Stem cells international

Wicki-Stordeur LE, Swayne LA.
PMID: 22754577
Stem Cells Int. 2012;2012:454180. doi: 10.1155/2012/454180. Epub 2012 Jun 13.

The birth of new neurons from unspecialized neural stem and progenitor cells surrounding the lateral ventricles occurs throughout postnatal life. This process, termed neurogenesis, is complex and multistepped, encompassing several types of cellular behaviours, such as proliferation, differentiation, and...

Gap junctions in C. elegans.

Frontiers in physiology

Simonsen KT, Moerman DG, Naus CC.
PMID: 24575048
Front Physiol. 2014 Feb 11;5:40. doi: 10.3389/fphys.2014.00040. eCollection 2014.

As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that surprisingly share no primary...

Role of connexin channels in the retinal light response of a diurnal rodent.

Frontiers in cellular neuroscience

Palacios-Muñoz A, Escobar MJ, Vielma A, Araya J, Astudillo A, Valdivia G, García IE, Hurtado J, Schmachtenberg O, Martínez AD, Palacios AG.
PMID: 25202238
Front Cell Neurosci. 2014 Aug 25;8:249. doi: 10.3389/fncel.2014.00249. eCollection 2014.

Several studies have shown that connexin channels play an important role in retinal neural coding in nocturnal rodents. However, the contribution of these channels to signal processing in the retina of diurnal rodents remains unclear. To gain insight into...

Role of connexins in human congenital heart disease: the chicken and egg problem.

Frontiers in pharmacology

Salameh A, Blanke K, Daehnert I.
PMID: 23760510
Front Pharmacol. 2013 Jun 03;4:70. doi: 10.3389/fphar.2013.00070. eCollection 2013.

Inborn cardiac diseases are among the most frequent congenital anomalies and are the main cause of death in infants within the first year of age in industrialized countries when not adequately treated. They can be divided into simple and...

Biphasic increase of gap junction coupling induced by dipyridamole in the rat aortic A-10 vascular smooth muscle cell line.

Journal of cell communication and signaling

Begandt D, Bader A, Dreyer L, Eisert N, Reeck T, Ngezahayo A.
PMID: 23483357
J Cell Commun Signal. 2013 Jun;7(2):151-60. doi: 10.1007/s12079-013-0196-4. Epub 2013 Mar 13.

The rat aortic smooth muscle cell line A-10 was used to investigate the effect of dipyridamole on the gap junction coupling of smooth muscle cells. The scrape loading/dye transfer (SL/DT) technique revealed that dipyridamole concentrations between 5 μM and...

Connexin and Pannexin hemichannels are regulated by redox potential.

Frontiers in physiology

Retamal MA.
PMID: 24611056
Front Physiol. 2014 Feb 25;5:80. doi: 10.3389/fphys.2014.00080. eCollection 2014.

Connexins (Cxs) and Pannexins (Panxs) are two non-related protein families, having both the property to form hemichannels at the plasma membrane. There are 21 genes coding for different Cx based proteins and only 3 for Panx. Under physiological conditions,...

A Barter Economy in Tumors: Exchanging Metabolites through Gap Junctions.

Cancers

Swietach P, Monterisi S.
PMID: 30669506
Cancers (Basel). 2019 Jan 20;11(1). doi: 10.3390/cancers11010117.

To produce physiological functions, many tissues require their cells to be connected by gap junctions. Such diffusive coupling is important in establishing a cytoplasmic syncytium through which cells can exchange signals, substrates and metabolites. Often the benefits of connectivity...

Showing 13 to 24 of 313 entries