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Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?.

Circulation research

Madhur MS, Elijovich F, Alexander MR, Pitzer A, Ishimwe J, Van Beusecum JP, Patrick DM, Smart CD, Kleyman TR, Kingery J, Peck RN, Laffer CL, Kirabo A.
PMID: 33793336
Circ Res. 2021 Apr 02;128(7):908-933. doi: 10.1161/CIRCRESAHA.121.318052. Epub 2021 Apr 01.

Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even after normalization of blood pressure in patients with hypertension. Underlying immune cell activation is a likely culprit. Although immune cells are important for protection against invading...

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Madhur MS, Elijovich F, Alexander MR, et al. Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?. Circ Res. 2021;128(7):908-933doi: 10.1161/CIRCRESAHA.121.318052.
Madhur, M. S., Elijovich, F., Alexander, M. R., Pitzer, A., Ishimwe, J., Van Beusecum, J. P., Patrick, D. M., Smart, C. D., Kleyman, T. R., Kingery, J., Peck, R. N., Laffer, C. L., & Kirabo, A. (2021). Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?. Circulation research, 128(7), 908-933. https://doi.org/10.1161/CIRCRESAHA.121.318052
Madhur, Meena S, et al. "Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?." Circulation research vol. 128,7 (2021): 908-933. doi: https://doi.org/10.1161/CIRCRESAHA.121.318052
Madhur MS, Elijovich F, Alexander MR, Pitzer A, Ishimwe J, Van Beusecum JP, Patrick DM, Smart CD, Kleyman TR, Kingery J, Peck RN, Laffer CL, Kirabo A. Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?. Circ Res. 2021 Apr 02;128(7):908-933. doi: 10.1161/CIRCRESAHA.121.318052. Epub 2021 Apr 01. PMID: 33793336; PMCID: PMC8023750.
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Introduction to the Aortic Valve Disease Review Series.

Circulation research

Cuevas RA, St Hilaire C.
PMID: 33914602
Circ Res. 2021 Apr 30;128(9):1327-1329. doi: 10.1161/CIRCRESAHA.121.319286. Epub 2021 Apr 29.

No abstract available.

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Cuevas RA, St Hilaire C. Introduction to the Aortic Valve Disease Review Series. Circ Res. 2021;128(9):1327-1329doi: 10.1161/CIRCRESAHA.121.319286.
Cuevas, R. A., & St Hilaire, C. (2021). Introduction to the Aortic Valve Disease Review Series. Circulation research, 128(9), 1327-1329. https://doi.org/10.1161/CIRCRESAHA.121.319286
Cuevas, Rolando A, and St Hilaire, Cynthia. "Introduction to the Aortic Valve Disease Review Series." Circulation research vol. 128,9 (2021): 1327-1329. doi: https://doi.org/10.1161/CIRCRESAHA.121.319286
Cuevas RA, St Hilaire C. Introduction to the Aortic Valve Disease Review Series. Circ Res. 2021 Apr 30;128(9):1327-1329. doi: 10.1161/CIRCRESAHA.121.319286. Epub 2021 Apr 29. PMID: 33914602; PMCID: PMC8406426.
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Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis.

Circulation research

Griffin JM, Rosenblum H, Maurer MS.
PMID: 33983835
Circ Res. 2021 May 14;128(10):1554-1575. doi: 10.1161/CIRCRESAHA.121.318187. Epub 2021 May 13.

Often considered a rare disease, cardiac amyloidosis is increasingly recognized by practicing clinicians. The increased rate of diagnosis is in part due the aging of the population and increasing incidence and prevalence of cardiac amyloidosis with advancing age, as...

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Griffin JM, Rosenblum H, Maurer MS. Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis. Circ Res. 2021;128(10):1554-1575doi: 10.1161/CIRCRESAHA.121.318187.
Griffin, J. M., Rosenblum, H., & Maurer, M. S. (2021). Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis. Circulation research, 128(10), 1554-1575. https://doi.org/10.1161/CIRCRESAHA.121.318187
Griffin, Jan M, et al. "Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis." Circulation research vol. 128,10 (2021): 1554-1575. doi: https://doi.org/10.1161/CIRCRESAHA.121.318187
Griffin JM, Rosenblum H, Maurer MS. Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis. Circ Res. 2021 May 14;128(10):1554-1575. doi: 10.1161/CIRCRESAHA.121.318187. Epub 2021 May 13. PMID: 33983835; PMCID: PMC8561842.
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IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Non-Obstructive Coronary Arteries.

Circulation research

Corban MT, Toya T, Albers DP, Sebaali F, Lewis B, Bois JPP, Gulati R, Prasad A, Best PJ, Bell M, Rihal C, Prasad M, Ahmad A, Lerman LO, Solseth ML, Winters JL, Dietz AB, Lerman A.
PMID: 34923853
Circ Res. 2021 Dec 20; doi: 10.1161/CIRCRESAHA.121.319644. Epub 2021 Dec 20.

No abstract available.

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Corban MT, Toya T, Albers DP, et al. IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Non-Obstructive Coronary Arteries. Circ Res. 2021;doi: 10.1161/CIRCRESAHA.121.319644.
Corban, M. T., Toya, T., Albers, D. P., Sebaali, F., Lewis, B., Bois, J. P. P., Gulati, R., Prasad, A., Best, P. J., Bell, M., Rihal, C., Prasad, M., Ahmad, A., Lerman, L. O., Solseth, M. L., Winters, J. L., Dietz, A. B., & Lerman, A. (2021). IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Non-Obstructive Coronary Arteries. Circulation research, . https://doi.org/10.1161/CIRCRESAHA.121.319644
Corban, Michel T, et al. "IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Non-Obstructive Coronary Arteries." Circulation research vol. (2021). doi: https://doi.org/10.1161/CIRCRESAHA.121.319644
Corban MT, Toya T, Albers DP, Sebaali F, Lewis B, Bois JPP, Gulati R, Prasad A, Best PJ, Bell M, Rihal C, Prasad M, Ahmad A, Lerman LO, Solseth ML, Winters JL, Dietz AB, Lerman A. IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Non-Obstructive Coronary Arteries. Circ Res. 2021 Dec 20; doi: 10.1161/CIRCRESAHA.121.319644. Epub 2021 Dec 20. PMID: 34923853.
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Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.

Circulation research

Schlegel M, Sharma M, Brown EJ, Newman AAC, Cyr Y, Afonso MS, Corr EM, Koelwyn GJ, van Solingen C, Guzman J, Farhat R, Nikain CA, Shanley LC, Peled D, Schmidt AM, Fisher EA, Moore KJ.
PMID: 34289717
Circ Res. 2021 Aug 20;129(5):530-546. doi: 10.1161/CIRCRESAHA.121.319313. Epub 2021 Jul 22.

[Figure: see text].

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Schlegel M, Sharma M, Brown EJ, et al. Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression. Circ Res. 2021;129(5):530-546doi: 10.1161/CIRCRESAHA.121.319313.
Schlegel, M., Sharma, M., Brown, E. J., Newman, A. A. C., Cyr, Y., Afonso, M. S., Corr, E. M., Koelwyn, G. J., van Solingen, C., Guzman, J., Farhat, R., Nikain, C. A., Shanley, L. C., Peled, D., Schmidt, A. M., Fisher, E. A., & Moore, K. J. (2021). Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression. Circulation research, 129(5), 530-546. https://doi.org/10.1161/CIRCRESAHA.121.319313
Schlegel, Martin, et al. "Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression." Circulation research vol. 129,5 (2021): 530-546. doi: https://doi.org/10.1161/CIRCRESAHA.121.319313
Schlegel M, Sharma M, Brown EJ, Newman AAC, Cyr Y, Afonso MS, Corr EM, Koelwyn GJ, van Solingen C, Guzman J, Farhat R, Nikain CA, Shanley LC, Peled D, Schmidt AM, Fisher EA, Moore KJ. Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression. Circ Res. 2021 Aug 20;129(5):530-546. doi: 10.1161/CIRCRESAHA.121.319313. Epub 2021 Jul 22. PMID: 34289717; PMCID: PMC8529357.
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Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease.

Circulation research

Alsaigh T, Di Bartolo BA, Mulangala J, Figtree GA, Leeper NJ.
PMID: 34110900
Circ Res. 2021 Jun 11;128(12):1927-1943. doi: 10.1161/CIRCRESAHA.121.318265. Epub 2021 Jun 10.

Peripheral arterial disease is a growing worldwide problem with a wide spectrum of clinical severity and is projected to consume >$21 billion per year in the United States alone. While vascular researchers have brought several therapies to the clinic...

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Alsaigh T, Di Bartolo BA, Mulangala J, et al. Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease. Circ Res. 2021;128(12):1927-1943doi: 10.1161/CIRCRESAHA.121.318265.
Alsaigh, T., Di Bartolo, B. A., Mulangala, J., Figtree, G. A., & Leeper, N. J. (2021). Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease. Circulation research, 128(12), 1927-1943. https://doi.org/10.1161/CIRCRESAHA.121.318265
Alsaigh, Tom, et al. "Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease." Circulation research vol. 128,12 (2021): 1927-1943. doi: https://doi.org/10.1161/CIRCRESAHA.121.318265
Alsaigh T, Di Bartolo BA, Mulangala J, Figtree GA, Leeper NJ. Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease. Circ Res. 2021 Jun 11;128(12):1927-1943. doi: 10.1161/CIRCRESAHA.121.318265. Epub 2021 Jun 10. PMID: 34110900; PMCID: PMC8208504.
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Vascular Impact of Cancer Therapies: The Case of BTK (Bruton Tyrosine Kinase) Inhibitors.

Circulation research

Fleming MR, Xiao L, Jackson KD, Beckman JA, Barac A, Moslehi JJ.
PMID: 34110908
Circ Res. 2021 Jun 11;128(12):1973-1987. doi: 10.1161/CIRCRESAHA.121.318259. Epub 2021 Jun 10.

Novel targeted cancer therapies have revolutionized oncology therapies, but these treatments can have cardiovascular complications, which include heterogeneous cardiac, metabolic, and vascular sequelae. Vascular side effects have emerged as important considerations in both cancer patients undergoing active treatment and...

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Fleming MR, Xiao L, Jackson KD, et al. Vascular Impact of Cancer Therapies: The Case of BTK (Bruton Tyrosine Kinase) Inhibitors. Circ Res. 2021;128(12):1973-1987doi: 10.1161/CIRCRESAHA.121.318259.
Fleming, M. R., Xiao, L., Jackson, K. D., Beckman, J. A., Barac, A., & Moslehi, J. J. (2021). Vascular Impact of Cancer Therapies: The Case of BTK (Bruton Tyrosine Kinase) Inhibitors. Circulation research, 128(12), 1973-1987. https://doi.org/10.1161/CIRCRESAHA.121.318259
Fleming, Matthew R, et al. "Vascular Impact of Cancer Therapies: The Case of BTK (Bruton Tyrosine Kinase) Inhibitors." Circulation research vol. 128,12 (2021): 1973-1987. doi: https://doi.org/10.1161/CIRCRESAHA.121.318259
Fleming MR, Xiao L, Jackson KD, Beckman JA, Barac A, Moslehi JJ. Vascular Impact of Cancer Therapies: The Case of BTK (Bruton Tyrosine Kinase) Inhibitors. Circ Res. 2021 Jun 11;128(12):1973-1987. doi: 10.1161/CIRCRESAHA.121.318259. Epub 2021 Jun 10. PMID: 34110908.
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Epidemiology of Peripheral Artery Disease and Polyvascular Disease.

Circulation research

Aday AW, Matsushita K.
PMID: 34110907
Circ Res. 2021 Jun 11;128(12):1818-1832. doi: 10.1161/CIRCRESAHA.121.318535. Epub 2021 Jun 10.

Atherosclerotic lower extremity peripheral artery disease (PAD) is increasingly recognized as an important cause of cardiovascular morbidity and mortality that affects >230 million people worldwide. Traditional cardiovascular risk factors, including advanced age, smoking, and diabetes, are strongly linked to...

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Aday AW, Matsushita K. Epidemiology of Peripheral Artery Disease and Polyvascular Disease. Circ Res. 2021;128(12):1818-1832doi: 10.1161/CIRCRESAHA.121.318535.
Aday, A. W., & Matsushita, K. (2021). Epidemiology of Peripheral Artery Disease and Polyvascular Disease. Circulation research, 128(12), 1818-1832. https://doi.org/10.1161/CIRCRESAHA.121.318535
Aday, Aaron W, and Matsushita, Kunihiro. "Epidemiology of Peripheral Artery Disease and Polyvascular Disease." Circulation research vol. 128,12 (2021): 1818-1832. doi: https://doi.org/10.1161/CIRCRESAHA.121.318535
Aday AW, Matsushita K. Epidemiology of Peripheral Artery Disease and Polyvascular Disease. Circ Res. 2021 Jun 11;128(12):1818-1832. doi: 10.1161/CIRCRESAHA.121.318535. Epub 2021 Jun 10. PMID: 34110907; PMCID: PMC8202714.
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Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury.

Circulation research

Xie M, Cho GW, Kong Y, Li DL, Altamirano F, Luo X, Morales CR, Jiang N, Schiattarella GG, May HI, Medina J, Shelton JM, Ferdous A, Gillette TG, Hill JA.
PMID: 34111934
Circ Res. 2021 Jul 23;129(3):435-450. doi: 10.1161/CIRCRESAHA.120.318601. Epub 2021 Jun 11.

[Figure: see text].

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Xie M, Cho GW, Kong Y, et al. Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury. Circ Res. 2021;129(3):435-450doi: 10.1161/CIRCRESAHA.120.318601.
Xie, M., Cho, G. W., Kong, Y., Li, D. L., Altamirano, F., Luo, X., Morales, C. R., Jiang, N., Schiattarella, G. G., May, H. I., Medina, J., Shelton, J. M., Ferdous, A., Gillette, T. G., & Hill, J. A. (2021). Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury. Circulation research, 129(3), 435-450. https://doi.org/10.1161/CIRCRESAHA.120.318601
Xie, Min, et al. "Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury." Circulation research vol. 129,3 (2021): 435-450. doi: https://doi.org/10.1161/CIRCRESAHA.120.318601
Xie M, Cho GW, Kong Y, Li DL, Altamirano F, Luo X, Morales CR, Jiang N, Schiattarella GG, May HI, Medina J, Shelton JM, Ferdous A, Gillette TG, Hill JA. Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury. Circ Res. 2021 Jul 23;129(3):435-450. doi: 10.1161/CIRCRESAHA.120.318601. Epub 2021 Jun 11. PMID: 34111934; PMCID: PMC8317428.
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Epidemiology and Genetics of Venous Thromboembolism and Chronic Venous Disease.

Circulation research

Baylis RA, Smith NL, Klarin D, Fukaya E.
PMID: 34110897
Circ Res. 2021 Jun 11;128(12):1988-2002. doi: 10.1161/CIRCRESAHA.121.318322. Epub 2021 Jun 10.

Venous disease is a term that broadly covers both venous thromboembolic disease and chronic venous disease. The basic pathophysiology of venous thromboembolism and chronic venous disease differ as venous thromboembolism results from an imbalance of hemostasis and thrombosis while...

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Baylis RA, Smith NL, Klarin D, et al. Epidemiology and Genetics of Venous Thromboembolism and Chronic Venous Disease. Circ Res. 2021;128(12):1988-2002doi: 10.1161/CIRCRESAHA.121.318322.
Baylis, R. A., Smith, N. L., Klarin, D., & Fukaya, E. (2021). Epidemiology and Genetics of Venous Thromboembolism and Chronic Venous Disease. Circulation research, 128(12), 1988-2002. https://doi.org/10.1161/CIRCRESAHA.121.318322
Baylis, Richard A, et al. "Epidemiology and Genetics of Venous Thromboembolism and Chronic Venous Disease." Circulation research vol. 128,12 (2021): 1988-2002. doi: https://doi.org/10.1161/CIRCRESAHA.121.318322
Baylis RA, Smith NL, Klarin D, Fukaya E. Epidemiology and Genetics of Venous Thromboembolism and Chronic Venous Disease. Circ Res. 2021 Jun 11;128(12):1988-2002. doi: 10.1161/CIRCRESAHA.121.318322. Epub 2021 Jun 10. PMID: 34110897; PMCID: PMC8487638.
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Contemporary Medical Management of Peripheral Artery Disease.

Circulation research

Bonaca MP, Hamburg NM, Creager MA.
PMID: 34110910
Circ Res. 2021 Jun 11;128(12):1868-1884. doi: 10.1161/CIRCRESAHA.121.318258. Epub 2021 Jun 10.

Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis. Modifiable risk factors including cigarette smoking, dyslipidemia, diabetes, poor diet quality, obesity, and physical inactivity, along with underlying genetic factors contribute to lower extremity atherosclerosis. Patients with PAD often...

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Bonaca MP, Hamburg NM, Creager MA. Contemporary Medical Management of Peripheral Artery Disease. Circ Res. 2021;128(12):1868-1884doi: 10.1161/CIRCRESAHA.121.318258.
Bonaca, M. P., Hamburg, N. M., & Creager, M. A. (2021). Contemporary Medical Management of Peripheral Artery Disease. Circulation research, 128(12), 1868-1884. https://doi.org/10.1161/CIRCRESAHA.121.318258
Bonaca, Marc P, et al. "Contemporary Medical Management of Peripheral Artery Disease." Circulation research vol. 128,12 (2021): 1868-1884. doi: https://doi.org/10.1161/CIRCRESAHA.121.318258
Bonaca MP, Hamburg NM, Creager MA. Contemporary Medical Management of Peripheral Artery Disease. Circ Res. 2021 Jun 11;128(12):1868-1884. doi: 10.1161/CIRCRESAHA.121.318258. Epub 2021 Jun 10. PMID: 34110910.
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Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia.

Circulation research

Chen Z, Liu J, Zhou F, Li H, Zhang XJ, She ZG, Lu Z, Cai J, Li H.
PMID: 34043417
Circ Res. 2021 May 28;128(11):1747-1765. doi: 10.1161/CIRCRESAHA.121.319059. Epub 2021 May 27.

Cardiac arrhythmias and the resulting sudden cardiac death are significant cardiovascular complications that continue to impose a heavy burden on patients and society. An emerging body of evidence indicates that nonalcoholic fatty liver disease (NAFLD) is closely associated with...

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Chen Z, Liu J, Zhou F, et al. Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia. Circ Res. 2021;128(11):1747-1765doi: 10.1161/CIRCRESAHA.121.319059.
Chen, Z., Liu, J., Zhou, F., Li, H., Zhang, X. J., She, Z. G., Lu, Z., Cai, J., & Li, H. (2021). Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia. Circulation research, 128(11), 1747-1765. https://doi.org/10.1161/CIRCRESAHA.121.319059
Chen, Ze, et al. "Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia." Circulation research vol. 128,11 (2021): 1747-1765. doi: https://doi.org/10.1161/CIRCRESAHA.121.319059
Chen Z, Liu J, Zhou F, Li H, Zhang XJ, She ZG, Lu Z, Cai J, Li H. Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia. Circ Res. 2021 May 28;128(11):1747-1765. doi: 10.1161/CIRCRESAHA.121.319059. Epub 2021 May 27. PMID: 34043417.
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Showing 781 to 792 of 797 entries