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Showing 769 to 780 of 797 entries
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Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas.

Circulation research

Hanna P, Dacey MJ, Brennan J, Moss A, Robbins S, Achanta S, Biscola NP, Swid MA, Rajendran PS, Mori S, Hadaya JE, Smith EH, Peirce SG, Chen J, Havton LA, Cheng ZJ, Vadigepalli R, Schwaber J, Lux RL, Efimov I, Tompkins JD, Hoover DB, Ardell JL, Shivkumar K.
PMID: 33629877
Circ Res. 2021 Apr 30;128(9):1279-1296. doi: 10.1161/CIRCRESAHA.120.318458. Epub 2021 Feb 25.

[Figure: see text].

Myofilament Phosphorylation in Stem Cell Treated Diastolic Heart Failure.

Circulation research

Soetkamp D, Gallet R, Parker SJ, Holewinski R, Venkatraman V, Peck K, Goldhaber JI, Marbán E, Van Eyk JE.
PMID: 34641704
Circ Res. 2021 Dec 03;129(12):1125-1140. doi: 10.1161/CIRCRESAHA.119.316311. Epub 2021 Oct 13.

RATIONALE: Phosphorylation of sarcomeric proteins has been implicated in heart failure with preserved ejection fraction (HFpEF); such changes may contribute to diastolic dysfunction by altering contractility, cardiac stiffness, CaOBJECTIVE: Phosphorylation changes that underlie HFpEF and those reversed by CDC...

Inflame on!: mitochondrial escape provokes cytokine storms that doom the heart.

Circulation research

Dorn GW.
PMID: 22821906
Circ Res. 2012 Jul 20;111(3):271-3. doi: 10.1161/CIRCRESAHA.112.275867.

Mitochondria are derived from primordial bacterial endosymbionts and retain partial genomes. In mammalian cells, damaged or dysfunctional mitochondria are recognized, targeted for elimination, then neatly packaged and eliminated via mitophagy. A recent paper from Oka et al describes how...

Antibodies to PCSK9: a superior way to lower LDL cholesterol?.

Circulation research

Maxwell KN, Breslow JL.
PMID: 22821907
Circ Res. 2012 Jul 20;111(3):274-7. doi: 10.1161/CIRCRESAHA.112.275859.

Lowering of LDL cholesterol, predominantly accomplished clinically by statins, is one of the key components of both the prevention and medical management of coronary atherosclerosis; however, additional or alternative cholesterol lowering agents are needed for patients who fail to...

PRMT5 Prevents Dilated Cardiomyopathy via Suppression of Protein O-GlcNAcylation.

Circulation research

Li Z, Xu J, Song Y, Xin C, Liu L, Hou N, Teng Y, Cheng X, Wang T, Yu Z, Song J, Zhang Y, Wang J, Yang X.
PMID: 34503365
Circ Res. 2021 Oct 15;129(9):857-871. doi: 10.1161/CIRCRESAHA.121.319456. Epub 2021 Sep 10.

[Figure: see text].

Phosphodiesterase 5: A Novel Therapeutic Target in Long QT Syndrome.

Circulation research

Zaza A, Lodola F.
PMID: 34473532
Circ Res. 2021 Sep 03;129(6):666-668. doi: 10.1161/CIRCRESAHA.121.319851. Epub 2021 Sep 02.

No abstract available.

N-Acetyl Transferases: New Insights Into Human Congenital Cardiovascular Defects.

Circulation research

Cashman TJ, Trivedi CM.
PMID: 33856919
Circ Res. 2021 Apr 16;128(8):1170-1172. doi: 10.1161/CIRCRESAHA.121.319049. Epub 2021 Apr 15.

No abstract available.

Gut Dysbiosis-Induced Hypertension Is Ameliorated by Intermittent Fasting.

Circulation research

Touyz RM.
PMID: 33914600
Circ Res. 2021 Apr 30;128(9):1255-1257. doi: 10.1161/CIRCRESAHA.121.319147. Epub 2021 Apr 29.

No abstract available.

A Compendium on Hypertension: New Advances and Future Impact.

Circulation research

Touyz RM, Schiffrin EL.
PMID: 33793329
Circ Res. 2021 Apr 02;128(7):803-807. doi: 10.1161/CIRCRESAHA.121.319181. Epub 2021 Apr 01.

No abstract available.

Device Therapy of Hypertension.

Circulation research

Mahfoud F, Schlaich MP, Lobo MD.
PMID: 33793330
Circ Res. 2021 Apr 02;128(7):1080-1099. doi: 10.1161/CIRCRESAHA.121.318091. Epub 2021 Apr 01.

In the past decade, efforts to improve blood pressure control have looked beyond conventional approaches of lifestyle modification and drug therapy to embrace interventional therapies. Based upon animal and human studies clearly demonstrating a key role for the sympathetic...

Pathophysiology of Hypertension: The Mosaic Theory and Beyond.

Circulation research

Harrison DG, Coffman TM, Wilcox CS.
PMID: 33793328
Circ Res. 2021 Apr 02;128(7):847-863. doi: 10.1161/CIRCRESAHA.121.318082. Epub 2021 Apr 01.

Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage. Over the years, Dr Page modified his paradigm,...

Vascular Stress Signaling in Hypertension.

Circulation research

Cicalese SM, da Silva JF, Priviero F, Webb RC, Eguchi S, Tostes RC.
PMID: 33793333
Circ Res. 2021 Apr 02;128(7):969-992. doi: 10.1161/CIRCRESAHA.121.318053. Epub 2021 Apr 01.

Cells respond to stress by activating a variety of defense signaling pathways, including cell survival and cell death pathways. Although cell survival signaling helps the cell to recover from acute insults, cell death or senescence pathways induced by chronic...

Showing 769 to 780 of 797 entries