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Showing 37 to 48 of 23887 entries
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Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.

Journal of extracellular vesicles

Durcin M, Fleury A, Taillebois E, Hilairet G, Krupova Z, Henry C, Truchet S, Trötzmüller M, Köfeler H, Mabilleau G, Hue O, Andriantsitohaina R, Martin P, Le Lay S.
PMID: 28473884
J Extracell Vesicles. 2017 Apr 10;6(1):1305677. doi: 10.1080/20013078.2017.1305677. eCollection 2017.

Extracellular vesicles (EVs) are biological vectors that can modulate the metabolism of target cells by conveying signalling proteins and genomic material. The level of EVs in plasma is significantly increased in cardiometabolic diseases associated with obesity, suggesting their possible...

Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice.

Experimental and therapeutic medicine

Kang SJ, Choi BR, Kim SH, Yi HY, Park HR, Song CH, Ku SK, Lee YJ.
PMID: 28413464
Exp Ther Med. 2017 Apr;13(4):1249-1266. doi: 10.3892/etm.2017.4109. Epub 2017 Feb 08.

In the present study, the complex anti-climacterium potential of standardized pomegranate concentrated solution (PCS) was investigated using bilateral ovariectomy (OVX) female ddY mice. Changes in body weight and gain during experimental periods, food consumption, serum estradiol levels, total body...

Effects of inspiratory muscle exercise in the pulmonary function, autonomic modulation, and hemodynamic variables in older women with metabolic syndrome.

Journal of exercise rehabilitation

Feriani DJ, Coelho HJ, Scapini KB, de Moraes OA, Mostarda C, Ruberti OM, Uchida MC, Caperuto ÉC, Irigoyen MC, Rodrigues B.
PMID: 28503537
J Exerc Rehabil. 2017 Apr 30;13(2):218-226. doi: 10.12965/jer.1734896.448. eCollection 2017 Apr.

The aim of the present study was to investigate the effects of inspiratory muscle exercise (IME) on metabolic and hemodynamic parameters, cardiac autonomic modulation and respiratory function of older women with metabolic syndrome (MS). For this, sixteen older women...

Effect of Daisaikoto on Expressions of SIRT1 and NF-kappaB of Diabetic Fatty Liver Rats Induced by High-Fat Diet and Streptozotocin.

Yonago acta medica

Qian W, Cai X, Zhang X, Wang Y, Qian Q, Hasegawa J.
PMID: 27493486
Yonago Acta Med. 2016 Jun 29;59(2):149-58. eCollection 2016 Jun.

BACKGROUND: Daisaikoto (DSKT), a classical traditional Chinese herbal formula, has been used for treating digestive diseases for 1800 years in China. Therefore, in this study, we are going to investigate the effect of DSKT on diabetic fatty liver rats...

Irisin levels are associated with urotensin II levels in diabetic patients.

Journal of diabetes investigation

He WY, Bai Q, A LT, Tang CS, Zhang AH.
PMID: 26417416
J Diabetes Investig. 2015 Sep;6(5):571-6. doi: 10.1111/jdi.12331. Epub 2015 Mar 12.

AIMS/INTRODUCTION: Irisin is a newly identified myokine that can promote energy expenditure. Previous studies showed that circulating urotensin II (UII) levels were increased in diabetes, and UII could inhibit the glucose transport in skeletal muscle in diabetic mice and...

Atherosclerosis severity is not affected by a deficiency in IL-33/ST2 signaling.

Immunity, inflammation and disease

Martin P, Palmer G, Rodriguez E, Woldt E, Mean I, James RW, Smith DE, Kwak BR, Gabay C.
PMID: 26417439
Immun Inflamm Dis. 2015 Sep;3(3):239-46. doi: 10.1002/iid3.62. Epub 2015 May 10.

Interleukin (IL)-33 is a cytokine of the IL-1 family, which signals through the ST2 receptor. Previous work demonstrated that the systemic administration of recombinant IL-33 reduces the development of atherosclerosis in apolipoprotein E-deficient (ApoE(-/-)) mice by inducing a Th1-to-Th2...

The Preventive Effect of Zuogui Wan on Offspring Rats' Impaired Glucose Tolerance Whose Mothers Had Gestational Diabetes Mellitus.

Evidence-based complementary and alternative medicine : eCAM

Wang Y, Feng Q, Niu X, Xu K, Wang Y, Wang J, Li Q, Mao Y, Gao S.
PMID: 27034700
Evid Based Complement Alternat Med. 2016;2016:9417362. doi: 10.1155/2016/9417362. Epub 2016 Feb 29.

In this experiment, we used streptozotocin (STZ) to establish a model of gestational diabetes mellitus (GDM) rats, where Zuogui Wan was given to GDM rats. After pregnancy, offspring rats were divided into 4 groups: control group, high fat and...

Association of the .

Balkan journal of medical genetics : BJMG

Bora K, Pathak MS, Borah P, Hussain MI, Das D.
PMID: 28924542
Balkan J Med Genet. 2017 Jun 30;20(1):59-70. doi: 10.1515/bjmg-2017-0002. eCollection 2017 Jun 30.

Cardiovascular disease (CVD) risk factors, and particularly decreased high density lipoprotein cholesterol (HDL-C) dyslipidemia are prevalent in Assam, India. This study was undertaken to investigate whether

CANHEART: Is HDL cholesterol a cardiovascular specific risk factor?.

Global cardiology science & practice

Hassan M, Philip P.
PMID: 28979903
Glob Cardiol Sci Pract. 2016 Dec 30;2016(4):e201634. doi: 10.21542/gcsp.2016.34.

Initial observational studies have identified high-density lipoprotein cholesterol (HDL-C) as an independent predictor of cardiovascular (CV) risk, even in patients on optimal statin therapy. However, the notion that higher HDL-C is better, has been seriously challenged by the results...

A Study of the Extended Lipid Profile including Oxidized LDL, Small Dense LDL, Lipoprotein (a) and Apolipoproteins in the Assessment of Cardiovascular Risk in Hypothyroid Patients.

Journal of clinical and diagnostic research : JCDR

Bansal SK, Yadav R.
PMID: 27504276
J Clin Diagn Res. 2016 Jun;10(6):BC04-8. doi: 10.7860/JCDR/2016/19775.8067. Epub 2016 Jun 01.

INTRODUCTION: Hypothyroidism is one of the most common metabolic disorders associated with dyslipidemia which poses a higher risk of Coronary Artery Disease (CAD) in such patients. Biochemical markers which can pick up the risk promptly are becoming imperative now-a-days...

Membrane Associated Progesterone Receptors: Promiscuous Proteins with Pleiotropic Functions - Focus on Interactions with Cytochromes P450.

Frontiers in pharmacology

Ryu CS, Klein K, Zanger UM.
PMID: 28396637
Front Pharmacol. 2017 Mar 27;8:159. doi: 10.3389/fphar.2017.00159. eCollection 2017.

Membrane-associated progesterone receptors (MAPR) are a group of four rather small, partially homologous proteins, which share a similar non-covalent heme-binding domain that is related to cytochrome b5, a well-known functional interaction partner of microsomal cytochrome P450 (CYP) monooxygenase systems....

Complex dynamics at the nanoscale in simple biomembranes.

Scientific reports

Sarangi NK, Ayappa KG, Basu JK.
PMID: 28894156
Sci Rep. 2017 Sep 11;7(1):11173. doi: 10.1038/s41598-017-11068-5.

Nature is known to engineer complex compositional and dynamical platforms in biological membranes. Understanding this complex landscape requires techniques to simultaneously detect membrane re-organization and dynamics at the nanoscale. Using super-resolution stimulated emission depletion (STED) microscopy coupled with fluorescence...

Showing 37 to 48 of 23887 entries