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Showing 13 to 24 of 23887 entries
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Structural and Functional Analysis of Apolipoprotein E3 Modification by a Lipid Peroxidation Product, 4‐Hydroxynonenal

Louis Stokes Alliances for Minority Participation AND Program Evaluation

Abdulhasan AF.
GSID: Pr-r5PT1Wo8J
AF Abdulhasan, MIU Abeer… - The FASEB …, 2020 - Wiley Online Library

Background Post mortem tissues from brains of Alzheimer's disease (AD) patients show higher levels of 4‐hydroxynonenal (4‐HNE)‐modified proteins, with 4‐HNE arising as a result of oxidative stress and lipid peroxidation. The overall goal of our study is to understand...

Risk factors for coronary heart disease. Selected recent epidemiological advances.

Drugs

Hulley SB.
PMID: 3076113
Drugs. 1988;36:1-4. doi: 10.2165/00003495-198800363-00003.

Several recent advances in our understanding of the epidemiology and prevention of coronary artery disease are presented, highlighting the current status of the 3 major risk factors: blood cholesterol, blood pressure and cigarette smoking. There is a striking analogy...

Primary prevention of coronary heart disease in the Federal Republic of Germany. Analysis of cost-effectiveness.

Drugs

Assmann G, Schulte H.
PMID: 2127007
Drugs. 1990;40:33-7. doi: 10.2165/00003495-199000401-00008.

The cost-effectiveness of a primary prevention strategy for coronary heart disease is reviewed in this paper. Five subgroups were identified, depending on the degree of medical intervention required to achieve a target low density lipoprotein (LDL)-cholesterol level of less...

Nutritional aspects of hypertension.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Seedat YK.
PMID: 2645663
S Afr Med J. 1989 Feb 18;75(4):175-7.

Hypertension is of importance mainly as a risk factor for heart, brain and kidney disease. To date, efforts have been made to reduce high blood pressure levels rather than to prevent their development, yet primary prevention of hypertension is...

Study of the correlation between the Type A behavior pattern in patients with coronary heart disease and the extent of coronary atherosclerosis.

The Tokai journal of experimental and clinical medicine

Tagawa R, Hosaka T.
PMID: 2087705
Tokai J Exp Clin Med. 1990 Mar;15(1):45-50.

To investigate the relationship between the coronary-prone behavior pattern (Type A behavior pattern) and coronary artery disease, 159 patients were evaluated by coronary angiography (CAG) and the coronary-prone behavior pattern score (CBP score) as well as other coronary risk...

Relationship between serum cystatin C and polycystic ovary syndrome.

Iranian journal of reproductive medicine

Gozashti MH, Gholamhosseinian A, Musavi F, Mashrouteh M.
PMID: 24639696
Iran J Reprod Med. 2013 Jan;11(1):71-6.

BACKGROUND: Polycystic ovary syndrome (PCOS) causes an increased risk of metabolic cardiovascular syndrome. Also, cystatin C serum levels are associated with the risk of cardiovascular events in metabolic syndrome patients.OBJECTIVE: To investigate the relationship between cystatin C in PCOS...

Impact of Lycium Barbarum Polysaccharide and Danshensu on vascular endothelial growth factor in the process of retinal neovascularization of rabbit.

International journal of ophthalmology

Tian XM, Wang R, Zhang BK, Wang CL, Guo H, Zhang SJ.
PMID: 23550271
Int J Ophthalmol. 2013;6(1):59-61. doi: 10.3980/j.issn.2222-3959.2013.01.12. Epub 2013 Feb 18.

AIM: To discuss the impact of Lycium Barbarum Polysaccharide (LBP) and Danshensu purified from Traditional Chinese Medicine (TCM) on vascular endothelial growth factor (VEGF) of rabbits with retinal neovascularization.METHODS: Forty rabbits were divided into normal control group, model control...

Atherosclerosis: from biology to pharmacological treatment.

Journal of geriatric cardiology : JGC

Riccioni G, Sblendorio V.
PMID: 23097661
J Geriatr Cardiol. 2012 Sep;9(3):305-17. doi: 10.3724/SP.J.1263.2012.02132.

A recent explosion in the amount of cardiovascular risk has swept across the globe. Primary prevention is the preferred method to lower cardiovascular risk. Lowering the prevalence of obesity is the most urgent matter, and is pleiotropic since it...

Affinity of estrogens for human progesterone receptor A and B monomers and risk of breast cancer: a comparative molecular modeling study.

Advances and applications in bioinformatics and chemistry : AABC

Hasan TN, B LG, Masoodi TA, Shafi G, Alshatwi AA, Sivashanmugham P.
PMID: 21918635
Adv Appl Bioinform Chem. 2011;4:29-36. doi: 10.2147/AABC.S17371. Epub 2011 Mar 08.

BACKGROUND: The human progesterone receptor (hPR) belongs to the steroid receptor family. It may be found as monomers (A and B) and or as a dimer (AB). hPR is regarded as the prognostic biomarker for breast cancer. In a...

The impact of initial statin treatment decisions on cardiovascular outcomes in clinical care settings: estimates using the Archimedes Model.

ClinicoEconomics and outcomes research : CEOR

van Herick A, Schuetz CA, Alperin P, Bullano MF, Balu S, Gandhi S.
PMID: 23180970
Clinicoecon Outcomes Res. 2012;4:337-47. doi: 10.2147/CEOR.S35487. Epub 2012 Nov 09.

PURPOSE: Many patients treated for dyslipidemia do not achieve recommended cholesterol goals despite the widespread availability of effective statins. Pharmaceutical claims show a strong tendency for patients to remain on their initially assigned treatment. With computer simulations, the impact...

Nutrigenomics approach elucidates health-promoting effects of high vegetable intake in lean and obese men.

Genes & nutrition

Pasman WJ, van Erk MJ, Klöpping WA, Pellis L, Wopereis S, Bijlsma S, Hendriks HF, Kardinaal AF.
PMID: 23595524
Genes Nutr. 2013 Sep;8(5):507-21. doi: 10.1007/s12263-013-0343-9. Epub 2013 Apr 18.

We aimed to explore whether vegetable consumption according to guidelines has beneficial health effects determined with classical biomarkers and nutrigenomics technologies. Fifteen lean (age 36 ± 7 years; BMI 23.4 ± 1.7 kg m(-2)) and 17 obese (age 40...

The relationship between coronary artery calcification and bone mineral density in patients according to their metabolic syndrome status.

Korean circulation journal

Lee HT, Shin J, Lim YH, Kim BK, Kim YT, Lee JU, Hong S, Song SY, Cho SH.
PMID: 21430992
Korean Circ J. 2011 Feb;41(2):76-82. doi: 10.4070/kcj.2011.41.2.76. Epub 2011 Feb 28.

BACKGROUND AND OBJECTIVES: The extent of coronary artery calcification (CAC) is closely related to total atherosclerotic plaque burden. However, the pathogenesis of CAC is still unclear. Conditions such as diabetes mellitus, renal failure, smoking, and chronic inflammation have been...

Showing 13 to 24 of 23887 entries