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Showing 361 to 367 of 367 entries
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Forty Years of Evidence on the Efficacy and Safety of Oral and Injectable Antibiotics for Treating Lyme Disease of Adults and Children: A Network Meta-Analysis.

Microbiology spectrum

Yang J, Wen S, Kong J, Yue P, Cao W, Xu X, Zhang Y, Chen J, Liu M, Fan Y, Luo L, Chen T, Li L, Li B, Dong Y, Luo S, Zhou G, Liu A, Bao F.
PMID: 34756070
Microbiol Spectr. 2021 Dec 22;9(3):e0076121. doi: 10.1128/Spectrum.00761-21. Epub 2021 Nov 10.

Lyme disease (LD) is a heavy public health burden. The most common manifestations of LD include erythema migrans (EM), Lyme neuroborreliosis (LNB), and Lyme arthritis (LA). The efficacy and safety of antibiotics for treating LD is still controversial. Thus,...

Post-traumatic endophthalmitis caused by streptococcus species in preschool children: clinical features, antibiotic susceptibilities and outcomes.

Eye (London, England)

Yang Y, Sui W, Duan F, Li Y, Zeng J, Jiang Z, Liu M, Yuan Z, Lin X.
PMID: 33627757
Eye (Lond). 2022 Jan;36(1):95-101. doi: 10.1038/s41433-021-01449-6. Epub 2021 Feb 24.

BACKGROUND/OBJECTIVES: Streptococcus is a common cause of post-traumatic endophthalmitis in children. This study aimed to analyse the clinical features, antibiotic susceptibilities and outcomes of traumatic endophthalmitis caused by streptococcus in preschool children.SUBJECTS/METHODS: Patients aged ≤6 years with traumatic streptococcal...

Weight-based cefuroxime dosing provides comparable orthopedic target tissue concentrations between weight groups - A microdialysis porcine study.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

Tøstesen SK, Hanberg P, Bue M, Thillemann TM, Falstie-Jensen T, Tøttrup M, Knudsen MB, Schmedes AV, Stilling M.
PMID: 34862642
APMIS. 2021 Dec 04; doi: 10.1111/apm.13198. Epub 2021 Dec 04.

Antibiotic prophylaxis is a key element in prevention of surgical site infections. For the majority of orthopedic procedures, antibiotic administration follows fixed dosing regimens irrespective of weight. However, this may result in insufficient antibiotic target tissue concentrations and higher...

Formulation and characterization of Cefuroxime Axetil nanoemulsion for improved bioavailability.

Journal of pharmacy & bioallied sciences

Patel Y, Poddar A, Sawant K.
PMID: 23066200
J Pharm Bioallied Sci. 2012 Mar;4:S4-5. doi: 10.4103/0975-7406.94116.

Cefuroxime Axetil nanoemulsion was formulated to address the problem of poor oral bioavailability. Formulation was manufactured utilizing Capmul MCM, Soya lecithin, Deoxycholic acid, Pluronic F127 and distilled water. Mean globular size of 121.3 nm was obtained. Drug content of...

Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States.

Antibiotics (Basel, Switzerland)

Maloney EL.
PMID: 34206379
Antibiotics (Basel). 2021 Jun 22;10(7). doi: 10.3390/antibiotics10070754.

Lyme disease, often characterized as a readily treatable infection, can be a debilitating and expensive illness, especially when patients remain symptomatic following therapy for early disease. Identifying and promoting highly effective therapeutic interventions for US patients with erythema migrans...

Short versus Long-Term Antibiotic Prophylaxis in Cesarean Section: A Randomized Clinical Trial.

Nigerian medical journal : journal of the Nigeria Medical Association

Adaji JA, Akaba GO, Isah AY, Yunusa T.
PMID: 33284877
Niger Med J. 2020 Jul-Aug;61(4):173-179. doi: 10.4103/nmj.NMJ_197_20. Epub 2020 Aug 04.

OBJECTIVE: The objective of the present study was to compare the efficacy of intravenous (IV) 48 h course of cefuroxime/metronidazole with long-term course using 48 h cefuroxime/metronidazole plus 5 days oral regimen of cefuroxime and metronidazole for the prevention...

Disparities in antimicrobial consumption and resistance within a country: the case of beta-lactams in Argentina.

Revista panamericana de salud publica = Pan American journal of public health

Boni S, Marin GH, Campaña L, Marin L, Corso A, Risso-Patron S, Gabriel F, Garay V, Limeres M.
PMID: 34322161
Rev Panam Salud Publica. 2021 Jul 26;45:e76. doi: 10.26633/RPSP.2021.76. eCollection 2021.

OBJECTIVE: To describe bacterial resistance and antimicrobial consumption ratio at the subnational level in Argentina during 2018, considering beta-lactams group as a case-study.METHODS: Antimicrobial consumption was expressed as defined daily doses (DDD)/1000 inhabitants. Resistance of RESULTS: The most widely...

Showing 361 to 367 of 367 entries