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Showing 37 to 48 of 1334 entries
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An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity.

JACC. Basic to translational science

Beak J, Huang W, Parker JS, Hicks ST, Patterson C, Simpson PC, Ma A, Jin J, Jensen BC.
PMID: 28286875
JACC Basic Transl Sci. 2017 Feb;2(1):39-53. doi: 10.1016/j.jacbts.2016.10.006.

α1A-ARs play adaptive and protective roles in the heart. Dabuzalgron is an oral selective α1A-AR agonist that was well tolerated in multiple clinical trials of treatment for urinary incontinence, but has never been used to treat heart disease in...

Age- and Gender-Normalized Coronary Incidence and Mortality Risks in Primary and Secondary Prevention.

Cardiology research

Puddu PE, Iannetta L, Schiariti M.
PMID: 28348687
Cardiol Res. 2012 Oct;3(5):193-204. doi: 10.4021/cr220w. Epub 2012 Sep 20.

Epidemiologic differences in ischemic heart disease incidence between women and men remain largely unexplained. The reasons of women's "protection" against coronary artery disease (CAD) are not still clear. However, there are subsets more likely to die of a first...

Influence of nucleoside triphosphates, inorganic salts, NADH, catecholamines, and oxygen saturation on nitrite-induced oxidation of rainbow trout haemoglobin.

Fish physiology and biochemistry

Jensen FB.
PMID: 24202690
Fish Physiol Biochem. 1993 Aug;12(2):111-7. doi: 10.1007/BF00004376.

Oxidation of rainbow trout haemoglobin (Hb) by nitrite proceeded via an initial lag phase followed by autocatalysis when the O2 saturation of the Hb was high. At low O2 saturations, the rate of methaemoglobin (metHb) formation was strongly reduced...

Endogenous angiotensins and catecholamines do not reduce skin blood flow or prevent hypotension in preterm piglets.

Physiological reports

Eiby YA, Lumbers ER, Staunton MP, Wright LL, Colditz PB, Wright IM, Lingwood BE.
PMID: 25538149
Physiol Rep. 2014 Dec 23;2(12). doi: 10.14814/phy2.12245. Print 2014 Dec 01.

Endocrine control of cardiovascular function is probably immature in the preterm infant; thus, it may contribute to the relative ineffectiveness of current adrenergic treatments for preterm cardiovascular compromise. This study aimed to determine the cardiovascular and hormonal responses to...

Mercury promotes catecholamines which potentiate mercurial autoimmunity and vasodilation: implications for inositol 1,4,5-triphosphate 3-kinase C susceptibility in kawasaki syndrome.

Korean circulation journal

Yeter D, Deth R, Kuo HC.
PMID: 24174958
Korean Circ J. 2013 Sep;43(9):581-91. doi: 10.4070/kcj.2013.43.9.581.

Previously, we reviewed biological evidence that mercury could induce autoimmunity and coronary arterial wall relaxation as observed in Kawasaki syndrome (KS) through its effects on calcium signaling, and that inositol 1,4,5-triphosphate 3-kinase C (ITPKC) susceptibility in KS would predispose...

Clinical characteristics and outcome of very elderly patients ≥90 years in intensive care: a retrospective observational study.

Annals of intensive care

Becker S, Müller J, de Heer G, Braune S, Fuhrmann V, Kluge S.
PMID: 26690798
Ann Intensive Care. 2015 Dec;5(1):53. doi: 10.1186/s13613-015-0097-1. Epub 2015 Dec 21.

BACKGROUND: Since the overall prognosis of very elderly patients is generally limited, admissions to intensive care in these patients are often restricted. Therefore, only very few information is available on the prognosis of nonagenarians after intensive care treatment. The...

Perioperative effects of high doses of intraoperative thymoglobulin induction in liver transplantation.

World journal of transplantation

De Pietri L, Serra V, Preziosi G, Rompianesi G, Begliomini B.
PMID: 26722660
World J Transplant. 2015 Dec 24;5(4):320-8. doi: 10.5500/wjt.v5.i4.320.

AIM: To describe our single-centre experience in liver transplantation (LT) with the infusion of high perioperative thymoglobulin doses. The optimal dosage and timing of thymoglobulin(®) [antithymocyte globulin (ATG)] administration during LT remains controversial. Cytokine release syndrome, haemolytic anaemia, thrombocytopenia,...

Perioperative visual loss following prone spinal surgery: A review.

Surgical neurology international

Epstein NE.
PMID: 27274409
Surg Neurol Int. 2016 May 17;7:S347-60. doi: 10.4103/2152-7806.182550. eCollection 2016.

BACKGROUND: Postoperative visual loss (POVL) following prone spine surgery occurs in from 0.013% to 1% of cases and is variously attributed to ischemic optic neuropathy (ION: anterior ION or posterior ION [reported in 1.9/10,000 cases: constitutes 89% of all...

Effects of Putative Neurotransmitters of the Carotid Body on its Own Glomus Cells.

The European journal of neuroscience

Eyzaguirre C, Monti-Bloch L, Woodbury JW.
PMID: 12106105
Eur J Neurosci. 1990 Jan;2(1):77-88. doi: 10.1111/j.1460-9568.1990.tb00383.x.

Carotid body glomus cells produce and release acetylcholine (ACh), catecholamines, and neuropeptides, and there is biochemical evidence that these cells possess receptors for these substances. Thus, we studied the effects of cholinergics [ACh, nicotine (Nic), bethanechol (BN)] and peptides...

Acute and chronic endocrine effects of noise: Review of the research conducted at the Institute for Water, Soil and Air Hygiene.

Noise & health

Ising H, Braun C.
PMID: 12689468
Noise Health. 2000;2(7):7-24.

This is a review of the research into endocrine effects of noise since the early 1980s at the Institute for Water, Soil and Air Hygiene. According to our knowledge, no other group has studied systematically the endocrine effects of...

Possible modulatory effect of endogenous islet catecholamines on insulin secretion.

BMC endocrine disorders

Borelli MI, Gagliardino JJ.
PMID: 11696250
BMC Endocr Disord. 2001;1(1):1. doi: 10.1186/1472-6823-1-1.

BACKGROUND: The possible participation of endogenous islet catecholamines (CAs) in the control of insulin secretion was tested. METHODS: Glucose-induced insulin secretion was measured in the presence of 3-Iodo-L-Tyrosine (MIT), a specific inhibitor of tyrosine-hydroxylase activity, in fresh and precultured...

Synthesis of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine, beta-adrenergic affinity, inotropic, chronotropic and coronary vasodilating activities.

European journal of medicinal chemistry

Iakovou K, Kazanis M, Vavayannis A, Bruni G, Romeo MR, Massarelli P, Teramoto S, Fujiki H, Mori T.
PMID: 10889316
Eur J Med Chem. 1999 Nov 01;34(11):903-917. doi: 10.1016/s0223-5234(99)00109-9.

Aseries of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine were synthesized and evaluated for inotropic, chronotropic and coronary vasodilating activities in the canine heart, affinity to beta(1)-adrenergic receptor in turkey erythrocytes and affinity to the beta(2)-adrenergic receptor in the rat lung. Among...

Showing 37 to 48 of 1334 entries