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Showing 25 to 36 of 7619 entries
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Chemoprevention of chemical-induced skin cancer by Panax ginseng root extract.

Journal of ginseng research

Sharma J, Goyal PK.
PMID: 26199559
J Ginseng Res. 2015 Jul;39(3):265-73. doi: 10.1016/j.jgr.2015.01.005. Epub 2015 Feb 07.

BACKGROUND: Cancer has emerged as a major health problem globally as a consequence to the increased longevity of the population, changing the environment and life style. Chemoprevention is a new and promising strategy for reducing cancer burden. Recently, some...

Drosophila melanogaster - an embryonic model for studying behavioral and biochemical effects of manganese exposure.

EXCLI journal

Ternes AP, Zemolin AP, da Cruz LC, da Silva GF, Saidelles AP, de Paula MT, Wagner C, Golombieski RM, Flores ÉM, Picoloto RS, Pereira AB, Franco JL, Posser T.
PMID: 26417337
EXCLI J. 2014 Nov 21;13:1239-53. eCollection 2014.

Embryonic animals are especially susceptible to metal exposure. Manganese (Mn) is an essential element, but in excess it can induce toxicity. In this study we used Drosophila melanogaster as an embryonic model to investigate biochemical and behavioral alterations due...

The Synthesis and Characterization of Highly Fluorescent Polycyclic Azaborine Chromophores.

The Journal of organic chemistry

Saint-Louis CJ, Magill LL, Wilson JA, Schroeder AR, Harrell SE, Jackson NS, Trindell JA, Kim S, Fisch AR, Munro L, Catalano VJ, Webster CE, Vaughan PP, Molek KS, Schrock AK, Huggins MT.
PMID: 27704820
J Org Chem. 2016 Nov 18;81(22):10955-10963. doi: 10.1021/acs.joc.6b01998. Epub 2016 Oct 25.

Six new heteroaromatic polycyclic azaborine chromophores were designed, synthesized, and investigated as easily tunable high-luminescent organic materials. The impact of the nitrogen-boron-hydroxy (N-BOH) unit in the azaborines was investigated by comparison with their N-carbonyl analogs. Insertion of the N-B(OH)-C...

The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression.

American journal of translational research

Cai N, Zhou W, Ye LL, Chen J, Liang QN, Chang G, Chen JJ.
PMID: 28861175
Am J Transl Res. 2017 Aug 15;9(8):3853-3866. eCollection 2017.

Currently, there is a considerable need to develop new treatments for osteosarcoma (OS), a very aggressive bone cancer. The activation of STAT3 signaling is positively associated with poor prognosis and aggressive progression in OS patients. Our previous study reported...

Placido disk-based topography versus high-resolution rotating Scheimpflug camera for corneal power measurements in keratoconic and post-LASIK eyes: reliability and agreement.

International journal of ophthalmology

Penna RR, de Sanctis U, Catalano M, Brusasco L, Grignolo FM.
PMID: 28393039
Int J Ophthalmol. 2017 Mar 18;10(3):453-460. doi: 10.18240/ijo.2017.03.20. eCollection 2017.

AIM: To compare the repeatability/reproducibility of measurement by high-resolution Placido disk-based topography with that of a high-resolution rotating Scheimpflug camera and assess the agreement between the two instruments in measuring corneal power in eyes with keratoconus and post-laser METHODS:...

Subchronic toxicity of Nile tilapia with different exposure routes to .

Veterinary world

Abdel-Latif HMR, Khashaba AMA.
PMID: 28919690
Vet World. 2017 Aug;10(8):955-963. doi: 10.14202/vetworld.2017.955-963. Epub 2017 Aug 21.

BACKGROUND: Toxic cyanobacterial blooms (AIM: Three-week subchronic exposure experiment was carried out on Nile tilapia, to determine their effects on fish behavior, tissues, liver functions, antioxidant enzymes, and lipid peroxidation.MATERIALS AND METHODS: Fish were exposed to four main treatments;...

Spectroscopic and kinetic evidence for redox cycling, catalase and degradation activities of Mn(III)(TPPS) in a basic aqueous peroxide medium.

Chemical communications (Cambridge, England)

Procner M, Orzeł Ł, Stochel G, van Eldik R.
PMID: 27000742
Chem Commun (Camb). 2016 Apr 18;52(30):5297-300. doi: 10.1039/c6cc01437b. Epub 2016 Mar 22.

Mn(III)(TPPS) was found to react rapidly with hydrogen peroxide in basic aqueous solution to form intermediate (TPPS)Mn(V)[double bond, length as m-dash]O and (TPPS)Mn(IV)[double bond, length as m-dash]O species which, in the presence of excess H2O2, are reduced fully back...

Ameliorative Effects of Chloroform Fraction of Cocos nucifera L. Husk Fiber Against Cisplatin-induced Toxicity in Rats.

Pharmacognosy research

Adaramoye OA, Azeez AF, Ola-Davies OE.
PMID: 27034598
Pharmacognosy Res. 2016 Apr-Jun;8(2):89-96. doi: 10.4103/0974-8490.172658.

BACKGROUND: Cisplatin (Cis) is used in the treatment of solid tumors and is known to elicit serious side effects.OBJECTIVE: The present study investigated the protective effects of chloroform fraction of Cocos nucifera husk fiber (CFCN) against Cis-induced organs' damage...

Antioxidant Levels in Cord Blood of Term Neonates and Its Association with Birth Weight.

Iranian journal of child neurology

Mirzarahimi M, Ahadi A, Bohlooli S, Namakikhalajan E, Barak M.
PMID: 27057185
Iran J Child Neurol. 2016;10(1):31-4.

OBJECTIVE: Due to excessive production of free radicals and antioxidants evolved mechanisms against oxidative stress, infants are very vulnerable. As there was a significant relation between antioxidant levels and birth weight, we aimed verify this relationship.MATERIALS & METHODS: In...

Therapeutic Potential of HGF-Expressing Human Umbilical Cord Mesenchymal Stem Cells in Mice with Acute Liver Failure.

International journal of hepatology

Tang Y, Li Q, Meng F, Huang X, Li C, Zhou X, Zeng X, He Y, Liu J, Hu X, Hu JF, Li T.
PMID: 27057357
Int J Hepatol. 2016;2016:5452487. doi: 10.1155/2016/5452487. Epub 2016 Feb 28.

Human umbilical cord-derived mesenchymal stem cells (UCMSCs) are particularly attractive cells for cellular and gene therapy in acute liver failure (ALF). However, the efficacy of this cell therapy in animal studies needs to be significantly improved before it can...

Acquisition, Maintenance and Relapse-Like Alcohol Drinking: Lessons from the UChB Rat Line.

Frontiers in behavioral neuroscience

Israel Y, Karahanian E, Ezquer F, Morales P, Ezquer M, Rivera-Meza M, Herrera-Marschitz M, Quintanilla ME.
PMID: 28420969
Front Behav Neurosci. 2017 Apr 04;11:57. doi: 10.3389/fnbeh.2017.00057. eCollection 2017.

This review article addresses the biological factors that influence: (i) the

The role of reactive oxygen species in myocardial redox signaling and regulation.

Annals of translational medicine

Moris D, Spartalis M, Tzatzaki E, Spartalis E, Karachaliou GS, Triantafyllis AS, Karaolanis GI, Tsilimigras DI, Theocharis S.
PMID: 28861421
Ann Transl Med. 2017 Aug;5(16):324. doi: 10.21037/atm.2017.06.17.

Reactive oxygen species (ROS) are subcellular messengers in gene regulatory and signal transduction pathways. In pathological situations, ROS accumulate due to excessive production or insufficient degradation, leading to oxidative stress (OS). OS causes oxidation of DNA, membranes, cellular lipids,...

Showing 25 to 36 of 7619 entries