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Showing 13 to 24 of 36 entries
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Stability of an extemporaneously compounded propylthiouracil suspension.

International journal of pharmaceutical compounding

Alexander KS, Mitra P.
PMID: 23924870
Int J Pharm Compd. 2005 Jan-Feb;9(1):82-6.

The stability of the antithyroid drug propylthiouracil was studied in an extemporaneously formulated suspension for 91 days. A simple, rapid, reproducible and stability-indicating reverse-phase high-performance liquid chromatographic assay method was developed for detecting propylthiouracil. The mobile phase consisted of...

Increasing particle size of a synthetic smectite for polymer nanocomposites using a supercritical hydrothermal treatment.

Journal of colloid and interface science

Ishii R, Teshima N, Ebina T, Mizukami F.
PMID: 20501339
J Colloid Interface Sci. 2010 Aug 15;348(2):313-21. doi: 10.1016/j.jcis.2010.04.058. Epub 2010 Apr 24.

We have studied the effect of a supercritical hydrothermal process on the structural and surface morphological properties of synthetic smectite clay, stevensite (ST), in terms of the particle size, in order to enhance the functionality of the synthetic smectites...

Rational Design of a Gel-Polymer-Inorganic Separator with Uniform Lithium-Ion Deposition for Highly Stable Lithium-Sulfur Batteries.

ACS applied materials & interfaces

Wang P, Bao J, Lv K, Zhang N, Chang Z, He P, Zhou H.
PMID: 31496219
ACS Appl Mater Interfaces. 2019 Oct 02;11(39):35788-35795. doi: 10.1021/acsami.9b12968. Epub 2019 Sep 20.

Lithium-sulfur (Li-S) batteries have received intense interest as next-generation electrochemical energy storage systems because of their high specific energy and natural abundance potential. However, its practical reality is seriously limited by the safety concerns from heterogeneous lithium deposition and...

Concurrent administration of acetaminophen and ethanol: impact on mouse liver and testis.

Journal of basic and clinical physiology and pharmacology

Aprioku JS, Gospel P.
PMID: 34898134
J Basic Clin Physiol Pharmacol. 2020 Dec 17;32(6):1065-1074. doi: 10.1515/jbcpp-2020-0136.

OBJECTIVES: Acetaminophen (paracetamol) and alcohol are widely consumed as analgesic/antipyretic and recreational agent, respectively. High doses of both agents induce liver and male reproductive toxicities. This study investigated the toxicological outcome of concurrent administration of paracetamol and ethanol in...

A Protective Role of Okadaic Acid in Liver Injury Induced by Amoxicillin.

Bulletin of experimental biology and medicine

Li D, Shi W, Lu X, Liu Z, Zhang S, Sun Y, Shi W, Zhu X.
PMID: 35006487
Bull Exp Biol Med. 2022 Jan 10; doi: 10.1007/s10517-022-05386-6. Epub 2022 Jan 10.

This study was performed to investigate whether okadaic acid (200 ng/kg) produces a protective effect in experimental liver injury induced by intragastric administration of 1000, 2000, and 4000 mg/kg amoxicillin in Sprague-Dawley rats (n=50). The control group was given...

The effects of lubricant eye drops on visual function as measured by the Inter-blink interval Visual Acuity Decay test.

Clinical ophthalmology (Auckland, N.Z.)

Torkildsen G.
PMID: 19789659
Clin Ophthalmol. 2009;3:501-6. doi: 10.2147/opth.s6225. Epub 2009 Sep 24.

OBJECTIVE: The purpose of the current study was to evaluate the effects of two marketed ocular lubricants on the visual decay in dry eye patients using the Inter-blink interval Visual Acuity Decay (IVAD) test.METHODS: This controlled, randomized, double-masked crossover...

Formulation and evaluation of nitrendipine buccal films.

Indian journal of pharmaceutical sciences

Nappinnai M, Chandanbala R, Balaijirajan R.
PMID: 21394260
Indian J Pharm Sci. 2008 Sep;70(5):631-5. doi: 10.4103/0250-474X.45402.

A mucoadhesive drug delivery system for systemic delivery of nitrendipine, a calcium channel blocker through buccal route was formulated. Mucoadhesive polymers like hydroxypropylmethylcellulose K-100, hydroxypropylcellulose, sodium carboxymethylcellulose, sodium alginate, polyvinyl alcohol, polyvinyl pyrrolidone K-30 and carbopol-934P were used for...

Salt-induced counterion condensation and related phenomena in sodium carboxymethylcellulose-sodium halide-methanol-water quaternary systems.

Soft matter

Das B, Chatterjee A.
PMID: 25925504
Soft Matter. 2015 May 28;11(20):4133-40. doi: 10.1039/c5sm00535c. Epub 2015 Apr 30.

Polyion-counterion interactions in sodium carboxymethylcellulose (NaCMC) in methanol-water media have been investigated conductometrically with reference to their variations with polyelectrolyte concentration, relative permittivity and the type and concentration of added electrolytes. The specific conductance data in polyelectrolyte-salt solutions were...

Evaluation of clinical outcomes in patients with dry eye disease using lubricant eye drops containing polyethylene glycol or carboxymethylcellulose.

Clinical ophthalmology (Auckland, N.Z.)

Cohen S, Martin A, Sall K.
PMID: 24403819
Clin Ophthalmol. 2014;8:157-64. doi: 10.2147/OPTH.S53822. Epub 2013 Dec 31.

BACKGROUND: The purpose of this study was to compare changes in corneal staining in patients with dry eye after 6 weeks of treatment with Systane® Gel Drops or Refresh Liquigel® lubricant eye drops.METHODS: Patients aged ≥18 years with a...

Improved Morphine-Loaded Hydrogels for Wound-Related Pain Relief.

Pharmaceutics

Mateus D, Marto J, Trindade P, Gonçalves H, Salgado A, Machado P, Melo-Gouveia A, Ribeiro HM, Almeida AJ.
PMID: 30759886
Pharmaceutics. 2019 Feb 12;11(2). doi: 10.3390/pharmaceutics11020076.

The use of morphine applied topically to painful wounds has potential advantages, such as dose reduction, fewer side effects and compound formulations, have been proposed for this purpose. Given the potential high impact of drug product quality on a...

Fluorescent and Mechanical Properties of Silicon Quantum Dots Modified Sodium Alginate-Carboxymethylcellulose Sodium Nanocomposite Bio-Polymer Films.

Polymers

Ji Y, Zhang H, Zhang C, Quan Z, Huang M, Wang L.
PMID: 31505896
Polymers (Basel). 2019 Sep 09;11(9). doi: 10.3390/polym11091476.

Highly luminescent silicon quantum dots (SiQDs) were prepared via one-pot hydrothermal route. Furthermore, the optimal synthetic conditions, dependence of the emission spectrum on the excitation wavelength and fluorescent stability of SiQDs were investigated by fluorescence spectroscopy. SiQDs exhibited bright...

[Transdermal delivery of diclofenac sodium gel after iontophoresis].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

Gao JQ, Wang H, Liang WQ, Chen MX.
PMID: 12601860
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2002 Aug;31(6):437-439. doi: 10.3785/j.issn.1008-9292.2002.06.009.

OBJECTIVE: To observe the in vivo effect of combined iontophoresis and laurocapram pretreatment on transdermal delivery of diclofenac sodium gel. METHODS: Diclofenac sodium gel was prepared using polyvinyl alcohol, carboxymethylcellulose sodium and hydroxypropylmethyl cellulose. The diclofenac blood level in...

Showing 13 to 24 of 36 entries