Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 25 to 34 of 34 entries
Sorted by: Best Match Show Resources per page
Calcium Dobesilate Versus Flavonoids for the Treatment of Early Hemorrhoidal Disease: A Randomized Controlled Trial.

Cureus

Changazi SH, Bhatti S, Choudary A, Rajput MNA, Iqbal Z, Ahmed QA.
PMID: 32953352
Cureus. 2020 Aug 18;12(8):e9845. doi: 10.7759/cureus.9845.

Background and Aim Early hemorrhoidal disease is usually treated conservatively with fiber diet and medical therapy with flavonoids or calcium dobesilate. The purpose of this study was to compare the efficacy of these two agents in the treatment of...

Effect of adding oral calcium dobesilate to laser photocoagulation on the macular thickness in patients with diabetic macular edema: a randomized clinical trial.

Advanced pharmaceutical bulletin

Feghhi M, Farrahi F, Abbaspour M, Takhtaeian A.
PMID: 25436194
Adv Pharm Bull. 2014 Dec;4(4):375-8. doi: 10.5681/apb.2014.055. Epub 2014 Aug 10.

PURPOSE: To evaluate the effect of oral calcium dobesilate (Doxium) on macular thickness in clinically significant macular edema (CSME).METHODS: Overall, 71 eyes of 40 patients with non-proliferative diabetic retinopathy and clinically significant macular edema were included. All patients were...

Therapeutic effects of calcium dobesilate on diabetic nephropathy mediated through reduction of expression of PAI-1.

Experimental and therapeutic medicine

Zhang X.
PMID: 23251286
Exp Ther Med. 2013 Jan;5(1):295-299. doi: 10.3892/etm.2012.755. Epub 2012 Oct 19.

The aim of this study was to investigate whether calcium dobesilate (calcium dihydroxy-2,5-benzenesulfonate) may be used to treat diabetic nephropathy. A total of 121 patients with type 2 diabetic nephropathy received calcium dobesilate (500 mg, 3 times a day)...

Study of Calcium Dobesilate in Diabetic Rats.

The International journal of angiology : official publication of the International College of Angiology, Inc

Ganado P, Ruiz E, Sanz M, Tejerina T.
PMID: 10191368
Int J Angiol. 1999;8(5):16-20. doi: 10.1007/BF01619844.

According to the World Health Organization (WHO) 74% of diabetic patients die of vascular complications. Previous reports have shown that endothelium-dependent relaxation of diabetic vasculature is more sensitive to free radical-induced injury. Calcium dobesilate (DOBE) has been successfully used...

Compound Danshen Dripping Pill for Treating Early Diabetic Retinopathy: A Randomized, Double-Dummy, Double-Blind Study.

Evidence-based complementary and alternative medicine : eCAM

Luo D, Qin Y, Yuan W, Deng H, Zhang Y, Jin M.
PMID: 26457110
Evid Based Complement Alternat Med. 2015;2015:539185. doi: 10.1155/2015/539185. Epub 2015 Sep 20.

This randomized, double-dummy, double-blind study was to observe the therapeutic effects of compound Danshen dripping pill (CDDP) in treating early diabetic retinopathy (DR). All the 57 type 2 diabetes cases in nonproliferative diabetic retinopathy (NPDR) stage were divided into...

Effects of calcium dobesilate on Nrf2, Keap1 and HO-1 in the lenses of D-galactose-induced cataracts in rats.

Experimental and therapeutic medicine

Sun J, Wang B, Hao Y, Yang X.
PMID: 29399076
Exp Ther Med. 2018 Jan;15(1):719-722. doi: 10.3892/etm.2017.5435. Epub 2017 Nov 03.

This study investigated the effects of calcium dobesilate on Nrf2, Keap1 and HO-1 in the lenses of D-galactose-induced cataracts in rats. Thirty Sprague-Dawley rats were randomly divided into three groups: a blank control group, a model control group and...

Prevalence of Idiopathic Cyclic Edema in Women with Lower Limb Lymphedema.

Journal of clinical medicine

Pereira de Godoy JM, Pereira de Godoy HJ, Pereira de Godoy LM, Guerreiro Godoy MF.
PMID: 29295565
J Clin Med. 2017 Dec 25;7(1). doi: 10.3390/jcm7010002.

Cyclic edema is a clinical condition in women that leads to fluid retention in the orthostatic position. The aim of the present study was to evaluate the prevalence of idiopathic cyclic edema in women with lower limb lymphedema. The...

Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress.

Antioxidants (Basel, Switzerland)

Hakimizadeh E, Zamanian M, Giménez-Llort L, Sciorati C, Nikbakhtzadeh M, Kujawska M, Kaeidi A, Hassanshahi J, Fatemi I.
PMID: 33922431
Antioxidants (Basel). 2021 Apr 23;10(5). doi: 10.3390/antiox10050649.

The long-term treatment of mice with D-galactose (D-gal) induces the overproduction of reactive oxygen species (ROS) and is a well-accepted experimental model of oxidative stress-linked cognitive disorders in physiological aging. Calcium dobesilate (CaD, Doxium

Correction: Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice.

PloS one

Njau F, Shushakova N, Schenk H, Wulfmeyer VC, Bollin R, Menne J, Haller H.
PMID: 33326477
PLoS One. 2020 Dec 16;15(12):e0244353. doi: 10.1371/journal.pone.0244353. eCollection 2020.

[This corrects the article DOI: 10.1371/journal.pone.0218494.].

A new method for anti-negative interference of calcium dobesilate in serum creatinine enzymatic analysis.

Journal of clinical laboratory analysis

Shen H, Chen K, Cao J.
PMID: 34329518
J Clin Lab Anal. 2021 Sep;35(9):e23928. doi: 10.1002/jcla.23928. Epub 2021 Jul 30.

BACKGROUND: Serum creatinine is a widely used biomarker for evaluating renal function. Sarcosine oxidase enzymatic (SOE) analysis is currently the most widely used method for the detection of creatinine. This method was negatively interfered with by calcium dobesilate, causing...

Showing 25 to 34 of 34 entries