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Showing 13 to 24 of 59 entries
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Stereospecific Intramolecular Arylation of 2- and 3-Pyridyl Substituted Alkylamines via Configurationally Stable α-Pyridyl Organolithiums.

Organic letters

Maury J, Zawodny W, Clayden J.
PMID: 28099031
Org Lett. 2017 Feb 03;19(3):472-475. doi: 10.1021/acs.orglett.6b03603. Epub 2017 Jan 18.

Treatment of N'-aryl urea derivatives of enantiomerically enriched α-(2-pyridyl) and α-(3-pyridyl)alkylamines with a base leads to the migration of the N'-aryl substituent from N to C in a 'nonclassical' intramolecular nucleophilic aromatic substitution reaction. Both electron-rich and -poor rings...

Towards the creation of a systems tip growth model for a pollen tube.

Plant signaling & behavior

Liu J, Hussey P.
PMID: 21474995
Plant Signal Behav. 2011 Apr;6(4):520-2. doi: 10.4161/psb.6.4.14750. Epub 2011 Apr 01.

Essential features of pollen tube growth are polarization of extracellular ion fluxes, intracellular ion gradients, and oscillating dynamics. These features in pollen tube growth are regulated by a wide range of spatiotemporally organized functions such as exocytosis and endocytosis,...

Cascading and Parallelising Curvilinear Inertial Focusing Systems for High Volume, Wide Size Distribution, Separation and Concentration of Particles.

Scientific reports

Miller B, Jimenez M, Bridle H.
PMID: 27808244
Sci Rep. 2016 Nov 03;6:36386. doi: 10.1038/srep36386.

Inertial focusing is a microfluidic based separation and concentration technology that has expanded rapidly in the last few years. Throughput is high compared to other microfluidic approaches although sample volumes have typically remained in the millilitre range. Here we...

A Comparison of Experimental and Broken Symmetry Density Functional Theory (BS-DFT) Calculated Electron Paramagnetic Resonance (EPR) Parameters for Intermediates Involved in the S.

The journal of physical chemistry. B

Beal NJ, Corry TA, O'Malley PJ.
PMID: 29300480
J Phys Chem B. 2018 Feb 01;122(4):1394-1407. doi: 10.1021/acs.jpcb.7b10843. Epub 2018 Jan 22.

A broken symmetry density functional theory (BS-DFT) magnetic analysis of the S

Ten simple rules for delivering live distance training in bioinformatics across the globe using webinars.

PLoS computational biology

Carvalho-Silva D, Garcia L, Morgan SL, Brooksbank C, Dunham I.
PMID: 30439935
PLoS Comput Biol. 2018 Nov 15;14(11):e1006419. doi: 10.1371/journal.pcbi.1006419. eCollection 2018 Nov.

No abstract available.

SnoopLigase Catalyzes Peptide-Peptide Locking and Enables Solid-Phase Conjugate Isolation.

Journal of the American Chemical Society

Buldun CM, Jean JX, Bedford MR, Howarth M.
PMID: 29402082
J Am Chem Soc. 2018 Feb 28;140(8):3008-3018. doi: 10.1021/jacs.7b13237. Epub 2018 Feb 14.

Simple, efficient reactions for connecting biological building-blocks open up many new possibilities. Here we have designed SnoopLigase, a protein that catalyzes site-specific transamidation, forming an isopeptide bond with more than 95% efficiency between two peptide tags, SnoopTagJr and DogTag....

A forum for 'doing society and genomics'. Science & Society Series on Convergence Research.

EMBO reports

Frow EK.
PMID: 19337301
EMBO Rep. 2009 Apr;10(4):318-21. doi: 10.1038/embor.2009.41.

No abstract available.

Non-UV light influences the degradation rate of crop protection products.

Environmental science & technology

Davies LO, Bramke I, France E, Marshall S, Oliver R, Nichols C, Schäfer H, Bending GD.
PMID: 23819841
Environ Sci Technol. 2013 Aug 06;47(15):8229-37. doi: 10.1021/es402139x. Epub 2013 Jul 12.

Crop protection products (CPPs) are subject to strict regulatory evaluation, including laboratory and field trials, prior to approval for commercial use. Laboratory tests lack environmental realism, while field trials are difficult to control. Addition of environmental complexity to laboratory...

Quantifying the impact and relevance of scientific research.

PloS one

Sutherland WJ, Goulson D, Potts SG, Dicks LV.
PMID: 22110667
PLoS One. 2011;6(11):e27537. doi: 10.1371/journal.pone.0027537. Epub 2011 Nov 16.

Qualitative and quantitative methods are being developed to measure the impacts of research on society, but they suffer from serious drawbacks associated with linking a piece of research to its subsequent impacts. We have developed a method to derive...

Systems biology and the virtual physiological human.

Molecular systems biology

Kohl P, Noble D.
PMID: 19638973
Mol Syst Biol. 2009;5:292. doi: 10.1038/msb.2009.51. Epub 2009 Jul 28.

No abstract available.

Mitochondrial disease: genetics and management.

Journal of neurology

Ng YS, Turnbull DM.
PMID: 26315846
J Neurol. 2016 Jan;263(1):179-91. doi: 10.1007/s00415-015-7884-3. Epub 2015 Aug 28.

Mitochondrial disease is one of the most common groups of genetic diseases with a minimum prevalence of greater than 1 in 5000 in adults. Whilst multi-system involvement is often evident, neurological manifestation is the principal presentation in most cases....

GOBLET: the Global Organisation for Bioinformatics Learning, Education and Training.

PLoS computational biology

Attwood TK, Atwood TK, Bongcam-Rudloff E, Brazas ME, Corpas M, Gaudet P, Lewitter F, Mulder N, Palagi PM, Schneider MV, van Gelder CW.
PMID: 25856076
PLoS Comput Biol. 2015 Apr 09;11(4):e1004143. doi: 10.1371/journal.pcbi.1004143. eCollection 2015 Apr.

In recent years, high-throughput technologies have brought big data to the life sciences. The march of progress has been rapid, leaving in its wake a demand for courses in data analysis, data stewardship, computing fundamentals, etc., a need that...

Showing 13 to 24 of 59 entries