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Showing 13 to 24 of 57184 entries
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Investigating association between second trimester maternal serum biomarkers and pre-term delivery.

Iranian journal of reproductive medicine

Sehat Z, Goshetasbi A, Taheri Amin M.
PMID: 24639737
Iran J Reprod Med. 2013 Feb;11(2):127-32.

BACKGROUND: Considering the effect of preterm delivery in morbidity and mortality of newborns, its precaution and prevention is so important.OBJECTIVE: To investigate the association between second trimester maternal serum biomarkers (Human Chorionic Gonadotropin, Alpha-fetoprotein, Non-conjugated estrogen, Inhibin A) and...

Breast cancer and protein biomarkers.

World journal of experimental medicine

Gam LH.
PMID: 24520539
World J Exp Med. 2012 Oct 20;2(5):86-91. doi: 10.5493/wjem.v2.i5.86. eCollection 2012 Oct 20.

Breast cancer is a healthcare concern of women worldwide. Despite procedures being available for diagnosis, prognosis and treatment of breast cancer, researchers are working intensively on the disease in order to improve the life quality of breast cancer patients....

Novel Biomarkers for Cardio-renal Syndrome.

Electrolyte & blood pressure : E & BP

Lee SR, Jeong KH.
PMID: 23508646
Electrolyte Blood Press. 2012 Dec;10(1):12-7. doi: 10.5049/EBP.2012.10.1.12. Epub 2012 Dec 31.

Cardio-renal syndrome (CRS) is a frequent and life-threatening syndrome. It is a disorder of the heart and kidneys in which acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in the other organ. Acute kidney...

Evaluation of ENA-6 Profile by ELISA Immunoassay in Patients with Systemic Lupus Erythematodes.

Autoimmune diseases

Aganovic-Musinovic I, Karamehic J, Zecevic L, Gavrankapetanovic F, Avdagic N, Zaciragic A, Jukic T, Grcic N, Svrakic S.
PMID: 23097694
Autoimmune Dis. 2012;2012:321614. doi: 10.1155/2012/321614. Epub 2012 Oct 11.

Autoimmune diseases occur in 3-5% of the population. Study included 30 patients with clinically diagnosed SLE and 30 healthy controls (American college of Rheumatology, 1997). SLE was diagnosed according to criteria issued in 1997 by the American College of...

The impact of initial statin treatment decisions on cardiovascular outcomes in clinical care settings: estimates using the Archimedes Model.

ClinicoEconomics and outcomes research : CEOR

van Herick A, Schuetz CA, Alperin P, Bullano MF, Balu S, Gandhi S.
PMID: 23180970
Clinicoecon Outcomes Res. 2012;4:337-47. doi: 10.2147/CEOR.S35487. Epub 2012 Nov 09.

PURPOSE: Many patients treated for dyslipidemia do not achieve recommended cholesterol goals despite the widespread availability of effective statins. Pharmaceutical claims show a strong tendency for patients to remain on their initially assigned treatment. With computer simulations, the impact...

Inflammation-induced atherosclerosis as a target for prevention of cardiovascular diseases from early life.

The open cardiovascular medicine journal

Kelishadi R.
PMID: 21804638
Open Cardiovasc Med J. 2010;4:24-9. doi: 10.2174/1874192401004020024. Epub 2010 Feb 23.

Atherogenesis starts from the fetal life, and its natural course consists of interrelations between traditional risk factors and inflammatory, immune, and endothelial biomarkers. Even the early-stages of atherosclerotic lesions, i.e. fatty streaks present the features of chronic inflammation. Markers...

Clinical asthma phenotypes and therapeutic responses.

ISRN pediatrics

Zedan M, Attia G, Zedan MM, Osman A, Abo-Elkheir N, Maysara N, Barakat T, Gamil N.
PMID: 23606983
ISRN Pediatr. 2013 Mar 31;2013:824781. doi: 10.1155/2013/824781. Print 2013.

Asthma is a heterogeneous disease that means not all asthmatics respond to the same treatment. We hypothesize an approach to characterize asthma phenotypes based on symptomatology (shortness of breath (SOB), cough, and wheezy phenotypes) in correlation with airway inflammatory...

Effect of DAPT, a gamma secretase inhibitor, on tumor angiogenesis in control mice.

Advanced biomedical research

Kalantari E, Saeidi H, Kia NS, Tahergorabi Z, Rashidi B, Dana N, Khazaei M.
PMID: 24520550
Adv Biomed Res. 2013 Nov 30;2:83. doi: 10.4103/2277-9175.122498. eCollection 2013.

BACKGROUND: Notch signaling is a key factor for angiogenesis in physiological and pathological condition and γ-secretase is the regulator of Notch signaling. The main goal of this study was to assess the effect of (N-[N-(3,5-Diflurophenaacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester) DAPT, a...

Nutrigenomics approach elucidates health-promoting effects of high vegetable intake in lean and obese men.

Genes & nutrition

Pasman WJ, van Erk MJ, Klöpping WA, Pellis L, Wopereis S, Bijlsma S, Hendriks HF, Kardinaal AF.
PMID: 23595524
Genes Nutr. 2013 Sep;8(5):507-21. doi: 10.1007/s12263-013-0343-9. Epub 2013 Apr 18.

We aimed to explore whether vegetable consumption according to guidelines has beneficial health effects determined with classical biomarkers and nutrigenomics technologies. Fifteen lean (age 36 ± 7 years; BMI 23.4 ± 1.7 kg m(-2)) and 17 obese (age 40...

Extracellular vesicles - biomarkers and effectors of the cellular interactome in cancer.

Frontiers in pharmacology

Rak J.
PMID: 23508692
Front Pharmacol. 2013 Mar 06;4:21. doi: 10.3389/fphar.2013.00021. eCollection 2013.

In multicellular organisms both health and disease are defined by patterns of communication between the constituent cells. In addition to networks of soluble mediators, cells are also programed to exchange complex messages pre-assembled as multimolecular cargo of membraneous structures...

Finding biomarkers in non-model species: literature mining of transcription factors involved in bovine embryo development.

BioData mining

Turenne N, Tiys E, Ivanisenko V, Yudin N, Ignatieva E, Valour D, Degrelle SA, Hue I.
PMID: 22931563
BioData Min. 2012 Aug 29;5(1):12. doi: 10.1186/1756-0381-5-12.

BACKGROUND: Since processes in well-known model organisms have specific features different from those in Bos taurus, the organism under study, a good way to describe gene regulation in ruminant embryos would be a species-specific consideration of closely related species...

Urinary monocyte chemotactic protein-1 and transforming growth factor-β in systemic lupus erythematosus.

Indian journal of nephrology

Torabinejad S, Mardani R, Habibagahi Z, Roozbeh J, Khajedehi P, Pakfetrat M, Banihashemi MA, Banihashemi SJ.
PMID: 22279336
Indian J Nephrol. 2012 Jan;22(1):5-12. doi: 10.4103/0971-4065.91179.

The purpose of this investigation was to assess the correlation of two biomarkers with the occurrence of renal flares in systemic lupus erythematosus (SLE). Urine levels of monocyte chemotactic protein-1 (MCP-1) and transforming growth factor beta (TGF-β) were measured...

Showing 13 to 24 of 57184 entries