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Significant toxicity following an increase in poisonings with designer benzodiazepines in the Netherlands between 2010 and 2020.

Drug and alcohol dependence

Essink S, Nugteren-van Lonkhuyzen JJ, van Riel AJHP, Dekker D, Hondebrink L.
PMID: 34998250
Drug Alcohol Depend. 2021 Dec 31;231:109244. doi: 10.1016/j.drugalcdep.2021.109244. Epub 2021 Dec 31.

BACKGROUND: Designer benzodiazepines (DBs) are an emerging class of new psychoactive substances. While structurally derived from pharmaceutical benzodiazepines, their toxicological profile is less clear. We investigated time trends in the rate of DB poisonings and their clinical toxicity.METHODS: A...

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Essink S, Nugteren-van Lonkhuyzen JJ, van Riel AJHP, et al. Significant toxicity following an increase in poisonings with designer benzodiazepines in the Netherlands between 2010 and 2020. Drug Alcohol Depend. 2021;231:109244doi: 10.1016/j.drugalcdep.2021.109244.
Essink, S., Nugteren-van Lonkhuyzen, J. J., van Riel, A. J. H. P., Dekker, D., & Hondebrink, L. (2021). Significant toxicity following an increase in poisonings with designer benzodiazepines in the Netherlands between 2010 and 2020. Drug and alcohol dependence, 231109244. https://doi.org/10.1016/j.drugalcdep.2021.109244
Essink, Sharon, et al. "Significant toxicity following an increase in poisonings with designer benzodiazepines in the Netherlands between 2010 and 2020." Drug and alcohol dependence vol. 231 (2021): 109244. doi: https://doi.org/10.1016/j.drugalcdep.2021.109244
Essink S, Nugteren-van Lonkhuyzen JJ, van Riel AJHP, Dekker D, Hondebrink L. Significant toxicity following an increase in poisonings with designer benzodiazepines in the Netherlands between 2010 and 2020. Drug Alcohol Depend. 2021 Dec 31;231:109244. doi: 10.1016/j.drugalcdep.2021.109244. Epub 2021 Dec 31. PMID: 34998250.
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High-Dose Benzodiazepines Positively Modulate GABA.

International journal of molecular sciences

Wang N, Lian J, Cao Y, Muheyati A, Yuan S, Ma Y, Zhang S, Yu G, Su R.
PMID: 35008465
Int J Mol Sci. 2021 Dec 21;23(1). doi: 10.3390/ijms23010042.

Benzodiazepines (BZDs) produce versatile pharmacological actions through positive modulation of GABA

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Wang N, Lian J, Cao Y, et al. High-Dose Benzodiazepines Positively Modulate GABA. Int J Mol Sci. 2021;23(1)doi: 10.3390/ijms23010042.
Wang, N., Lian, J., Cao, Y., Muheyati, A., Yuan, S., Ma, Y., Zhang, S., Yu, G., & Su, R. (2021). High-Dose Benzodiazepines Positively Modulate GABA. International journal of molecular sciences, 23(1), . https://doi.org/10.3390/ijms23010042
Wang, Na, et al. "High-Dose Benzodiazepines Positively Modulate GABA." International journal of molecular sciences vol. 23,1 (2021). doi: https://doi.org/10.3390/ijms23010042
Wang N, Lian J, Cao Y, Muheyati A, Yuan S, Ma Y, Zhang S, Yu G, Su R. High-Dose Benzodiazepines Positively Modulate GABA. Int J Mol Sci. 2021 Dec 21;23(1). doi: 10.3390/ijms23010042. PMID: 35008465.
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Improving time for administration of second-line antiseizure medications for children with generalized convulsive status epilepticus using quality improvement methodology.

Epilepsia

Vidaurre J, Albert DVF, Parker W, Naprawa J, Mittlesteadt J, Idris AS, Patel AD.
PMID: 34328222
Epilepsia. 2021 Oct;62(10):2496-2504. doi: 10.1111/epi.17026. Epub 2021 Jul 30.

OBJECTIVE: Status epilepticus is a life-threatening neurological emergency. However, delay in median time to administration of second-line antiseizure medication exists. The aim of this quality improvement initiative was to decrease the average delay before fosphenytoin is administered for pediatric...

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Vidaurre J, Albert DVF, Parker W, et al. Improving time for administration of second-line antiseizure medications for children with generalized convulsive status epilepticus using quality improvement methodology. Epilepsia. 2021;62(10):2496-2504doi: 10.1111/epi.17026.
Vidaurre, J., Albert, D. V. F., Parker, W., Naprawa, J., Mittlesteadt, J., Idris, A. S., & Patel, A. D. (2021). Improving time for administration of second-line antiseizure medications for children with generalized convulsive status epilepticus using quality improvement methodology. Epilepsia, 62(10), 2496-2504. https://doi.org/10.1111/epi.17026
Vidaurre, Jorge, et al. "Improving time for administration of second-line antiseizure medications for children with generalized convulsive status epilepticus using quality improvement methodology." Epilepsia vol. 62,10 (2021): 2496-2504. doi: https://doi.org/10.1111/epi.17026
Vidaurre J, Albert DVF, Parker W, Naprawa J, Mittlesteadt J, Idris AS, Patel AD. Improving time for administration of second-line antiseizure medications for children with generalized convulsive status epilepticus using quality improvement methodology. Epilepsia. 2021 Oct;62(10):2496-2504. doi: 10.1111/epi.17026. Epub 2021 Jul 30. PMID: 34328222.
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Variation in Prehospital Protocols for Pediatric Seizure Within the United States.

Pediatric emergency care

Ramgopal S, McCans K, Martin-Gill C, Owusu-Ansah S.
PMID: 32011553
Pediatr Emerg Care. 2021 Dec 01;37(12):e1331-e1338. doi: 10.1097/PEC.0000000000002029.

OBJECTIVE: The objective of this study was to compare statewide prehospital protocols for the management of pediatric seizures.METHODS: We performed a descriptive analysis comparing statewide protocols for emergency medical services management of pediatric seizures within the United States, excluding...

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Ramgopal S, McCans K, Martin-Gill C, et al. Variation in Prehospital Protocols for Pediatric Seizure Within the United States. Pediatr Emerg Care. 2021;37(12):e1331-e1338doi: 10.1097/PEC.0000000000002029.
Ramgopal, S., McCans, K., Martin-Gill, C., & Owusu-Ansah, S. (2021). Variation in Prehospital Protocols for Pediatric Seizure Within the United States. Pediatric emergency care, 37(12), e1331-e1338. https://doi.org/10.1097/PEC.0000000000002029
Ramgopal, Sriram, et al. "Variation in Prehospital Protocols for Pediatric Seizure Within the United States." Pediatric emergency care vol. 37,12 (2021): e1331-e1338. doi: https://doi.org/10.1097/PEC.0000000000002029
Ramgopal S, McCans K, Martin-Gill C, Owusu-Ansah S. Variation in Prehospital Protocols for Pediatric Seizure Within the United States. Pediatr Emerg Care. 2021 Dec 01;37(12):e1331-e1338. doi: 10.1097/PEC.0000000000002029. PMID: 32011553.
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"I'm pretty sure it's either food poisoning or Covid-19": Lived experience versus medical knowledge in diagnosing substance use problems.

The International journal on drug policy

Frank D.
PMID: 34183237
Int J Drug Policy. 2021 Dec;98:103348. doi: 10.1016/j.drugpo.2021.103348. Epub 2021 Jun 14.

People who use drugs, or who have in the past, often report that doctors and/or treatment providers devalue, or are unwilling to believe their claims in regards to substance use issues, in particular the presence and severity of withdrawal....

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Frank D. "I'm pretty sure it's either food poisoning or Covid-19": Lived experience versus medical knowledge in diagnosing substance use problems. Int J Drug Policy. 2021;98:103348doi: 10.1016/j.drugpo.2021.103348.
Frank, D. (2021). "I'm pretty sure it's either food poisoning or Covid-19": Lived experience versus medical knowledge in diagnosing substance use problems. The International journal on drug policy, 98103348. https://doi.org/10.1016/j.drugpo.2021.103348
Frank, David. ""I'm pretty sure it's either food poisoning or Covid-19": Lived experience versus medical knowledge in diagnosing substance use problems." The International journal on drug policy vol. 98 (2021): 103348. doi: https://doi.org/10.1016/j.drugpo.2021.103348
Frank D. "I'm pretty sure it's either food poisoning or Covid-19": Lived experience versus medical knowledge in diagnosing substance use problems. Int J Drug Policy. 2021 Dec;98:103348. doi: 10.1016/j.drugpo.2021.103348. Epub 2021 Jun 14. PMID: 34183237; PMCID: PMC8200310.
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Showing 2185 to 2189 of 2189 entries