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Showing 13 to 24 of 145 entries
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Pull-off force measurements between rough surfaces by atomic force microscopy.

Journal of colloid and interface science

Beach ER, Tormoen GW, Drelich J, Han R.
PMID: 16290443
J Colloid Interface Sci. 2002 Mar 01;247(1):84-99. doi: 10.1006/jcis.2001.8126.

Direct measurements of the pull-off (adhesion) forces between pharmaceutical particles (beclomethasone dipropionate, a peptide-type material, and lactose) with irregular geometry and rough polymeric surfaces (series of polypropylene coatings, polycarbonate, and acrylonitrile-butadiene-styrene) were carried out using the atomic force microscope....

Efficacy and Safety of Salmeterol/Fluticasone Propionate Combination Delivered by the Diskustrade mark or Pressurised Metered-Dose Inhaler in Children with Asthma.

Clinical drug investigation

Bracamonte T, Schauer U, Emeryk A, Godwood A, Balsara S.
PMID: 17523742
Clin Drug Investig. 2005;25(1):1-11. doi: 10.2165/00044011-200525010-00001.

BACKGROUND AND OBJECTIVE: Salmeterol and fluticasone propionate are well established in the treatment of childhood asthma, and their combination is effective in children aged 4-11 years. Asthma guidelines recommend that the inhaler device best suited to the individual should...

Regulation of CYP3A genes by glucocorticoids in human lung cells.

F1000Research

Roberts JK, Moore CD, Romero EG, Ward RM, Yost GS, Reilly CA.
PMID: 24555085
F1000Res. 2013 Aug 13;2:173. doi: 10.12688/f1000research.2-173.v2. eCollection 2013.

Inhaled glucocorticoids are the first-line treatment for patients with persistent asthma.  However, approximately thirty percent of patients exhibit glucocorticoid insensitivity, which may involve excess metabolic clearance of the glucocorticoids by CYP3A enzymes in the lung.  CYP3A4, 3A5, and 3A7...

A study of inhaled beclomethasone dipropionate therapy in asthma.

Canadian family physician Medecin de famille canadien

Epstein SW, Thompson GL.
PMID: 21308039
Can Fam Physician. 1976 Mar;22:62-6.

Fourteen patients with asthma have been followed in a long term clinical trial of the inhaled synthetic corticosteroid, beclomethasone dipropionate. All the patients were corticosteroid-dependent, with significant corticosteroid adverse effects. Twelve of the patients were able to stay on...

Can HLA-DRB4 Help to Identify Asthmatic Patients at Risk of Churg-Strauss Syndrome?.

ISRN rheumatology

Bottero P, Motta F, Bonini M, Vecchio F, Ierna F, Cuppari I, Sinico RA.
PMID: 24734195
ISRN Rheumatol. 2014 Mar 06;2014:843804. doi: 10.1155/2014/843804. eCollection 2014.

HLA-DRB4 gene is associated with Churg-Strauss syndrome (CSS), a systemic eosinophilic vasculitis with a prodromal phase characterized by severe asthma, eosinophilia, nasal polyposis, and sinusitis. Aim of this study was to evaluate if the presence of HLA-DRB4 in asthmatic...

Evaluation of Efficacy of Different Topical Corticosteroids.

Indian journal of dermatology, venereology and leprology

Prasad G, Prasad BN.
PMID: 28150628
Indian J Dermatol Venereol Leprol. 1986 Jan-Feb;52(1):30-32.

Four different, proprietary preparations of topical cortico-steroids in cream base were evaluated for their relative efficacy on forty adult human volunteers using a modification of the method described by Reddy and Singh. Fluocinolone acetonide 0.025% (Flucort) was rated to...

Asthma as a hidden disease in rural China: opportunities and challenges of standard case management.

Public health action

Kan XH, Chiang CY, Enarson DA, Rao HL, Chen Q, Aït-Khaled N, Chen GW.
PMID: 26392959
Public Health Action. 2012 Sep 21;2(3):87-91. doi: 10.5588/pha.12.0025.

OBJECTIVE: To assess the implementation of standard case management of asthma in Huaiyuan County, Anhui Province, China, in 2008.DESIGN: The study project began with the local adaptation of international asthma guidelines, followed by a situation analysis, pre-intervention study, training...

Efficacy of pharmacological agents for ulcerative proctitis: a systematic literature review.

Journal of Crohn's & colitis

Caron B, Sandborn WJ, Panaccione R, Schreiber S, Hart A, Solitano V, Danese S, Peyrin-Biroulet L.
PMID: 34850857
J Crohns Colitis. 2021 Nov 30; doi: 10.1093/ecco-jcc/jjab218. Epub 2021 Nov 30.

BACKGROUND: Ulcerative proctitis is a common and often highly symptomatic form of inflammatory bowel disease. We performed a systematic review to assess the efficacy of different therapies in the management of patients with ulcerative proctitis.METHODS: We identified randomized controlled...

Association between inhaled corticosteroid use and SARS-CoV-2 infection: A nationwide population-based study in South Korea.

Tuberculosis and respiratory diseases

Lee SC, Son KJ, Han CH, Jung JY, Park SC.
PMID: 34844402
Tuberc Respir Dis (Seoul). 2021 Nov 30; doi: 10.4046/trd.2021.0102. Epub 2021 Nov 30.

BACKGROUND: Inhaled corticosteroid (ICS) use may increase the risk of respiratory infection, but its influence on the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is not known. This study aimed to investigate the association between ICS...

Serum Inhaled Corticosteroid Detection for Monitoring Adherence in Severe Asthma.

The journal of allergy and clinical immunology. In practice

Alahmadi FH, Keevil B, Elsey L, George K, Niven R, Fowler SJ.
PMID: 34153519
J Allergy Clin Immunol Pract. 2021 Dec;9(12):4279-4287.e6. doi: 10.1016/j.jaip.2021.05.041. Epub 2021 Jun 18.

BACKGROUND: Daily inhaled corticosteroids (ICSs) are fundamental to asthma management, but adherence is low.OBJECTIVES: To investigate (1) whether LC-MS/MS could be used to detect ICSs in serum and (2) whether serum levels related to markers of disease severity.METHODS: We...

Comparative Effectiveness and Safety of Different Types of Inhaled Long-Acting β.

Chest

Wang MT, Lai JH, Huang YL, Liou JT, Cheng SH, Lin CW, Pan HY, Hsu YJ, Tsai CL.
PMID: 34023320
Chest. 2021 Oct;160(4):1255-1270. doi: 10.1016/j.chest.2021.05.025. Epub 2021 May 21.

BACKGROUND: Despite multiple available fixed-dose combinations (FDCs) of inhaled long-acting βRESEARCH QUESTION: Can comparative effectiveness and safety of LABA plus LAMA (LABA/LAMA) and LABA plus ICS (LABA/ICS) FDCs vary by different individual components of the dual combinations in COPD?STUDY...

Loading of Beclomethasone in Liposomes and Hyalurosomes Improved with Mucin as Effective Approach to Counteract the Oxidative Stress Generated by Cigarette Smoke Extract.

Nanomaterials (Basel, Switzerland)

Manca ML, Ferraro M, Pace E, Di Vincenzo S, Valenti D, Fernàndez-Busquets X, Peptu CA, Manconi M.
PMID: 33810420
Nanomaterials (Basel). 2021 Mar 26;11(4). doi: 10.3390/nano11040850.

In this work beclomethasone dipropionate was loaded into liposomes and hyalurosomes modified with mucin to improve the ability of the payload to counteract the oxidative stress and involved damages caused by cigarette smoke in the airway. The vesicles were...

Showing 13 to 24 of 145 entries