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Showing 13 to 24 of 943 entries
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Visible-light-mediated C2-amination of thiophenes by using DDQ as an organophotocatalyst.

Chemical communications (Cambridge, England)

Song C, Yi H, Dou B, Li Y, Singh AK, Lei A.
PMID: 28294249
Chem Commun (Camb). 2017 Mar 28;53(26):3689-3692. doi: 10.1039/c7cc01339f.

In this work, a direct C-H activation of thiophenes was presented via an oxidation pathway under visible-light irradiation, in which the thiophene radical cation serves as the key intermediate. Various thiophenes and azoles could be transformed into the corresponding...

Lonafarnib synergizes with azoles against Aspergillus spp. and Exophiala spp.

Medical mycology

Qiao J, Sun Y, Gao L, He C, Zheng W.
PMID: 29514275
Med Mycol. 2019 Feb 01;57(2):e1. doi: 10.1093/mmy/myx072.

No abstract available.

Frontiers in microbiology

Lv QZ, Qin YL, Yan L, Wang L, Zhang C, Jiang YY.
PMID: 29515531
Front Microbiol. 2018 Feb 20;9:218. doi: 10.3389/fmicb.2018.00218. eCollection 2018.

Antifungal azole drugs inhibit the synthesis of ergosterol and cause the accumulation of sterols containing a 14α-methyl group, which is related to the properties of cell membrane. Due to the frequent recurrence of fungal infections and clinical long-term prophylaxis,...

Photo-induced oxidant-free oxidative C-H/N-H cross-coupling between arenes and azoles.

Nature communications

Niu L, Yi H, Wang S, Liu T, Liu J, Lei A.
PMID: 28145410
Nat Commun. 2017 Feb 01;8:14226. doi: 10.1038/ncomms14226.

Direct cross-coupling between simple arenes and heterocyclic amines under mild conditions is undoubtedly important for C-N bonds construction. Selective C(sp

Palladium-catalyzed intermolecular carbonylative cross-coupling of heteroaryl C(sp.

Chemical communications (Cambridge, England)

Xing Q, Lv H, Xia C, Li F.
PMID: 28612071
Chem Commun (Camb). 2017 Jun 22;53(51):6914-6917. doi: 10.1039/c7cc03274a.

An efficient palladium-catalyzed oxidative aminocarbonylation of azoles has been developed. This system allows for intermolecular carbonylative cross-coupling of aromatic C(sp

Microwave-assisted one pot three-component synthesis of some novel pyrazole scaffolds as potent anticancer agents.

Chemistry Central journal

Gomha SM, Edrees MM, Faty RAM, Muhammad ZA, Mabkhot YN.
PMID: 29086808
Chem Cent J. 2017 May 08;11(1):37. doi: 10.1186/s13065-017-0266-4.

BACKGROUND: Pyrazoles, thiazoles and 1,3,4-thiadiazoles have been reported to possess various pharmacological activities.RESULTS: An efficient and a novel approach for the synthesis of some novel pyrazole based-azoles are described via multi-component reaction under controlled microwave heating conditions. The structures...

A DFT study of adsorption of imidazole, triazole, and tetrazole on oxidized copper surfaces: Cu₂O(111) and Cu₂O(111)-w/o-CuCUS.

Physical chemistry chemical physics : PCCP

Gustinčič D, Kokalj A.
PMID: 26443103
Phys Chem Chem Phys. 2015 Nov 21;17(43):28602-15. doi: 10.1039/c5cp03647j.

Azoles and their derivatives are known for their corrosion inhibition ability for copper. For this reason the bonding of imidazole, triazole, and tetrazole-used as archetypal models of azole corrosion inhibitors-to Cu2O(111) and Cu2O(111)-w/o-Cu(CUS) was characterized using density functional theory...

Antifungal prophylaxis in stem cell transplantation centers in Turkey.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Akan H.
PMID: 27264583
Turk J Haematol. 2011 Dec 05;28(4):271-5. doi: 10.5152/tjh.2011.81.

OBJECTIVE: This study aimed to determine the current state of antifungal prophylaxis in Turkish stem cell transplantation (SCT) centers.METHODS: he were 38 active stem cell transplantation centers in Turkey, 28 of which were registered with the European Group for...

Cyclosporine/ketoconazole reduces treatment costs for nephrotic syndrome.

Indian journal of nephrology

Iyengar A, Kamath N, Phadke KD, Bitzan M.
PMID: 24339519
Indian J Nephrol. 2013 Nov;23(6):419-23. doi: 10.4103/0971-4065.120338.

Cyclosporine A (CyA) is an effective agent for the treatment of glucocorticoid-dependent idiopathic nephrotic syndrome (GCDNS), but costs are prohibitive in resource-poor societies. The objectives of this study were to evaluate the efficacy and safety of reducing the dose...

Fluconazole Resistance Candida albicans in Females With Recurrent Vaginitis and Pir1 Overexpression.

Jundishapur journal of microbiology

Nasrollahi Z, Yadegari MH, Roudbar Mohammadi S, Roudbary M, Hosseini Poor M, Nikoomanesh F, Rajabi Bazl M.
PMID: 26495107
Jundishapur J Microbiol. 2015 Sep 23;8(9):e21468. doi: 10.5812/jjm.21468. eCollection 2015 Sep.

BACKGROUND: Some genes may be associated with Candida albicans resistance to azoles. Pir1 gene is described as responsible to induce resistance in C. albicans.OBJECTIVES: The current study aimed to find the relationship between fluconazole resistance and Pir1 protein (Pir1p)...

Reversible solid-to-liquid phase transition of coordination polymer crystals.

Journal of the American Chemical Society

Umeyama D, Horike S, Inukai M, Itakura T, Kitagawa S.
PMID: 25530162
J Am Chem Soc. 2015 Jan 21;137(2):864-70. doi: 10.1021/ja511019u. Epub 2015 Jan 09.

The solid-to-liquid phase transition, a fundamental process commonly observed for various types of substances with significant potential for application, has been given little attention in the field of coordination polymers (CPs) despite the rich functionality of these compounds. In...

NOV-002, A Glutathione Disulfide Mimetic, Suppresses Tumor Cell Invasion and Metastasis.

Journal of carcinogenesis & mutagenesis

Gumireddy K, Li A, Cao L, Yan J, Liu L, Xu X, Pazoles C, Huang Q.
PMID: 24377058
J Carcinog Mutagen. 2013 Apr 30;2013. doi: 10.4172/2157-2518.S7-002.

Metastasis is the major cause of death in cancer. Most therapies currently in the clinic aim to eradicate primary tumor, but do not have ideal effects on metastasis. The lack of effective therapy in metastasis prevention and treatment results...

Showing 13 to 24 of 943 entries