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Showing 25 to 36 of 69 entries
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Increased Visit-to-Visit Liver Enzyme Variability Is Associated with Incident Diabetes: A Community-Based 12-Year Prospective Cohort Study.

Diabetes & metabolism journal

Bang K, Jun JE, Jeong IK, Ahn KJ, Chung HY, Hwang YC.
PMID: 33725763
Diabetes Metab J. 2021 Nov;45(6):890-898. doi: 10.4093/dmj.2020.0208. Epub 2021 Mar 17.

BACKGROUND: Fatty liver and/or increased liver enzyme values have been reported to be associated with incident diabetes. We sought to determine whether increased visit-to-visit liver enzyme variability is associated with incident diabetes.METHODS: Study participants were recruited from the Korean...

Immuno- and hepato-toxicity of dichloroacetic acid in MRL(+/+) and B(6)C(3)F(1) mice.

Journal of immunotoxicology

Cai P, Boor PJ, Khan MF, Kaphalia BS, Ansari GA, Konig R.
PMID: 18958719
J Immunotoxicol. 2007 Apr;4(2):107-15. doi: 10.1080/15476910701337225.

Dichloroacetic acid (DCA) is a by-product of chlorination that occurs in drinking water disinfected with chlorine. Metabolism of trichloroethene (TCE) also generates DCA. TCE exposure is associated with the development of autoimmune diseases, which may be induced by TCE...

Metabolic syndrome is linked to a mild elevation in liver aminotransferases in diabetic patients with undetectable non-alcoholic fatty liver disease by ultrasound.

Diabetology & metabolic syndrome

Esteghamati A, Jamali A, Khalilzadeh O, Noshad S, Khalili M, Zandieh A, Morteza A, Nakhjavani M.
PMID: 21047423
Diabetol Metab Syndr. 2010 Nov 03;2:65. doi: 10.1186/1758-5996-2-65.

BACKGROUND: Despite ongoing findings on the relationship between elevated levels of alanine and aspartate aminotransferases (ALT and AST) and metabolic syndrome (MetS), this association in diabetic patients without a known cause for liver enzymes elevation other than diabetes, per...

The effect of helicobacter pylori eradication on liver fat content in subjects with non-alcoholic Fatty liver disease: a randomized open-label clinical trial.

Hepatitis monthly

Jamali R, Mofid A, Vahedi H, Farzaneh R, Dowlatshahi S.
PMID: 24358044
Hepat Mon. 2013 Dec 06;13(12):e14679. doi: 10.5812/hepatmon.14679. eCollection 2013.

BACKGROUND: The role of Helicobacter pylori (HP) in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) is unclear.OBJECTIVES: The aim of this study was to evaluate the effect of HP eradication on liver fat content (LFC), liver function tests...

Senna occidentalis leaf extract possesses antitrypanosomal activity and ameliorates the trypanosome-induced anemia and organ damage.

Pharmacognosy research

Ibrahim MA, Aliyu AB, Sallau AB, Bashir M, Yunusa I, Umar TS.
PMID: 21808562
Pharmacognosy Res. 2010 May;2(3):175-80. doi: 10.4103/0974-8490.65513.

The in vitro and in vivo antitrypanosomal effects of the ethanol extract of Senna occidentalis leaf were investigated. The crude extract exhibited an in vitro activity against Trypanosoma brucei brucei as it completely eliminated parasites' motility within 10 minutes...

Greater Biosynthetic Liver Dysfunction in Primary Sclerosing Cholangitis Suggests Co-existent or Impending Cholangiocarcinoma.

Journal of clinical and translational hepatology

Trilianos P, Agnihotri A, Ucbilek E, Gurakar A.
PMID: 27047765
J Clin Transl Hepatol. 2016 Mar 28;4(1):1-4. doi: 10.14218/JCTH.2015.00048. Epub 2016 Mar 15.

Background and Aim : Patients with primary sclerosing cholangitis (PSC) who develop cholangiocarcinoma (CCA) have a median survival of less than 6 months. In half of cases, PSC and CCA will be diagnosed either concurrently or within a year...

Aspartate aminotransferases ofPanicum miliaceum L. andPanicum antidotale retz. : Inactivation and reconstitution.

Planta

Balkow C, Wildner GF.
PMID: 24276278
Planta. 1982 Sep;154(5):477-84. doi: 10.1007/BF01267817.

L-Aspartate: 2-oxoglutarate transaminase was isolated and partially purified from leaves ofPanicum miliaceum (C4, NAD-malic enzyme type) and ofPanicum antidotale (C4, NADP-malic enzyme type). In each preparation two isoenzymes with different kinetic properties could be characterized. The enzyme activity was...

Efficacy of curcumin/turmeric on liver enzymes in patients with non-alcoholic fatty liver disease: A systematic review of randomized controlled trials.

Integrative medicine research

Mansour-Ghanaei F, Pourmasoumi M, Hadi A, Joukar F.
PMID: 30949432
Integr Med Res. 2019 Mar;8(1):57-61. doi: 10.1016/j.imr.2018.07.004. Epub 2018 Jul 27.

BACKGROUND: Several studies reported that curcumin supplementation could improve non-alcoholic fatty liver disease (NAFLD). The aim of this study was to evaluate the efficacy of curcumin/turmeric supplementation on liver enzymes in patients with NAFLD.METHODS: PubMed, Scopus, Web of Science...

Therapeutic activity of sour orange albedo extract and abundant flavanones loaded silica nanoparticles against acrylamide-induced hepatotoxicity.

Toxicology reports

Rizk MZ, Abo-El-Matty DM, Aly HF, Abd-Alla HI, Saleh SM, Younis EA, Elnahrawy AM, Haroun AA.
PMID: 30294554
Toxicol Rep. 2018 Sep 09;5:929-942. doi: 10.1016/j.toxrep.2018.08.021. eCollection 2018.

The current research aims to demonstrate the therapeutic effect of sour orange albedo extract (SOAE) and two flavanones loaded-tetraethylorthosilicate (TEOS) using sol-gel technique, in adose100 mg/kg body weight taken orally or45 days against acrylamide (ACR)toxicity in rats. This was...

Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model.

Journal of ethnopharmacology

Xu Z, Lin S, Tong Z, Chen S, Cao Y, Li Q, Jiang Y, Cai W, Tong Y, Zahra BS, Wang P.
PMID: 34848360
J Ethnopharmacol. 2021 Nov 27;285:114873. doi: 10.1016/j.jep.2021.114873. Epub 2021 Nov 27.

ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicine considers that the etiology and pathogenesis of non-alcoholic fatty liver disease (NAFLD) are related to liver depression and qi stagnation. Saffron and its active ingredient, crocetin (CCT), are used for the treatment of metabolic...

Specificity of aspartate aminotransferases from leguminous plants for 4-substituted glutamic acids.

Plant physiology

Winter HC, Dekker EE.
PMID: 16666674
Plant Physiol. 1989 Apr;89(4):1122-8. doi: 10.1104/pp.89.4.1122.

Aspartate aminotransferase (glutamate-oxalacetate transaminase) was partially purified from extracts of germinating seeds of peanut (Arachis hypogaea), honey locust (Gleditsia triacanthos), soybean (Glycine max), and Sophora japonica. The ability of these enzyme preparations, as well as aspartate aminotransferase purified from...

Efficacy and Safety of Metreleptin in Patients with Partial Lipodystrophy: Lessons from an Expanded Access Program.

Journal of diabetes & metabolism

Ajluni N, Dar M, Xu J, Neidert AH, Oral EA.
PMID: 27642538
J Diabetes Metab. 2016 Mar;7(3). doi: 10.4172/2155-6156.1000659. Epub 2016 Mar 23.

OBJECTIVE: Patients with lipodystrophy have severe metabolic abnormalities (insulin resistance, diabetes, and hypertriglyceridemia) that may increase morbidity and mortality. Metreleptin is approved by the United States Food and Drug Administration for treatment of generalized forms of lipodystrophy. We aimed...

Showing 25 to 36 of 69 entries