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Showing 1 to 12 of 69 entries
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Evaluation of Iron Oxide Nanoparticles Toxicity on Liver Cells of BALB/c Rats.

Iranian Red Crescent medical journal

Parivar K, Malekvand Fard F, Bayat M, Alavian SM, Motavaf M.
PMID: 26889399
Iran Red Crescent Med J. 2016 Jan 30;18(1):e28939. doi: 10.5812/ircmj.28939. eCollection 2016 Jan.

BACKGROUND: Because of their unique magnetic properties, Fe3O4 nanoparticles (Fe3O4-NPs) have extensive applications in various biomedical aspects. Investigation of the possible adverse aspects of these particles has lagged far behind their fast growing application.OBJECTIVES: The current study aimed to...

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Parivar K, Malekvand Fard F, Bayat M, et al. Evaluation of Iron Oxide Nanoparticles Toxicity on Liver Cells of BALB/c Rats. Iran Red Crescent Med J. 2016;18(1):e28939doi: 10.5812/ircmj.28939.
Parivar, K., Malekvand Fard, F., Bayat, M., Alavian, S. M., & Motavaf, M. (2016). Evaluation of Iron Oxide Nanoparticles Toxicity on Liver Cells of BALB/c Rats. Iranian Red Crescent medical journal, 18(1), e28939. https://doi.org/10.5812/ircmj.28939
Parivar, Kazem, et al. "Evaluation of Iron Oxide Nanoparticles Toxicity on Liver Cells of BALB/c Rats." Iranian Red Crescent medical journal vol. 18,1 (2016): e28939. doi: https://doi.org/10.5812/ircmj.28939
Parivar K, Malekvand Fard F, Bayat M, Alavian SM, Motavaf M. Evaluation of Iron Oxide Nanoparticles Toxicity on Liver Cells of BALB/c Rats. Iran Red Crescent Med J. 2016 Jan 30;18(1):e28939. doi: 10.5812/ircmj.28939. eCollection 2016 Jan. PMID: 26889399; PMCID: PMC4753026.
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MicroRNAs in Drug-induced Liver Injury.

Journal of clinical and translational hepatology

Li LM, Wang D, Zen K.
PMID: 26357624
J Clin Transl Hepatol. 2014 Sep;2(3):162-9. doi: 10.14218/JCTH.2014.00015. Epub 2014 Sep 15.

Drug-induced liver injury (DILI) is a leading cause of acute liver failure, and a major reason for the recall of marketed drugs. Detection of potential liver injury is a challenge for clinical management and preclinical drug safety studies, as...

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Li LM, Wang D, Zen K. MicroRNAs in Drug-induced Liver Injury. J Clin Transl Hepatol. 2014;2(3):162-9doi: 10.14218/JCTH.2014.00015.
Li, L. M., Wang, D., & Zen, K. (2014). MicroRNAs in Drug-induced Liver Injury. Journal of clinical and translational hepatology, 2(3), 162-9. https://doi.org/10.14218/JCTH.2014.00015
Li, Li-Min, et al. "MicroRNAs in Drug-induced Liver Injury." Journal of clinical and translational hepatology vol. 2,3 (2014): 162-9. doi: https://doi.org/10.14218/JCTH.2014.00015
Li LM, Wang D, Zen K. MicroRNAs in Drug-induced Liver Injury. J Clin Transl Hepatol. 2014 Sep;2(3):162-9. doi: 10.14218/JCTH.2014.00015. Epub 2014 Sep 15. PMID: 26357624; PMCID: PMC4521241.
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The effects of ecstasy on liver function tests, blood glucose, and lipids profile of male rats.

International journal of high risk behaviors & addiction

Shahraki MR, Irani M.
PMID: 25741481
Int J High Risk Behav Addict. 2014 Sep 17;3(4):e21076. doi: 10.5812/ijhrba.21076. eCollection 2014 Dec.

BACKGROUND: Ecstasy is used to improve mood and cordiality; however, based on some reports, it is neurotoxic to human users.OBJECTIVES: Because of the euphoria induced by MDMA (3,4-methylenedioxymethamphetamine) on the users, its consumption is increasing in almost all countries....

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Shahraki MR, Irani M. The effects of ecstasy on liver function tests, blood glucose, and lipids profile of male rats. Int J High Risk Behav Addict. 2014;3(4):e21076doi: 10.5812/ijhrba.21076.
Shahraki, M. R., & Irani, M. (2014). The effects of ecstasy on liver function tests, blood glucose, and lipids profile of male rats. International journal of high risk behaviors & addiction, 3(4), e21076. https://doi.org/10.5812/ijhrba.21076
Shahraki, Mohammad Reza, and Irani, Mahdieh. "The effects of ecstasy on liver function tests, blood glucose, and lipids profile of male rats." International journal of high risk behaviors & addiction vol. 3,4 (2014): e21076. doi: https://doi.org/10.5812/ijhrba.21076
Shahraki MR, Irani M. The effects of ecstasy on liver function tests, blood glucose, and lipids profile of male rats. Int J High Risk Behav Addict. 2014 Sep 17;3(4):e21076. doi: 10.5812/ijhrba.21076. eCollection 2014 Dec. PMID: 25741481; PMCID: PMC4331654.
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Non-alcoholic Fatty Liver Disease and Chronic Kidney Disease in Koreans Aged 50 Years or Older.

Korean journal of family medicine

Ahn AL, Choi JK, Kim MN, Kim SA, Oh EJ, Kweon HJ, Cho DY.
PMID: 23730487
Korean J Fam Med. 2013 May;34(3):199-205. doi: 10.4082/kjfm.2013.34.3.199. Epub 2013 May 24.

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) share common pathogenic mechanisms and many risk factors, and both are linked to an increased risk of cardiovascular diseases. The aim of this study was to assess the...

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Ahn AL, Choi JK, Kim MN, et al. Non-alcoholic Fatty Liver Disease and Chronic Kidney Disease in Koreans Aged 50 Years or Older. Korean J Fam Med. 2013;34(3):199-205doi: 10.4082/kjfm.2013.34.3.199.
Ahn, A. L., Choi, J. K., Kim, M. N., Kim, S. A., Oh, E. J., Kweon, H. J., & Cho, D. Y. (2013). Non-alcoholic Fatty Liver Disease and Chronic Kidney Disease in Koreans Aged 50 Years or Older. Korean journal of family medicine, 34(3), 199-205. https://doi.org/10.4082/kjfm.2013.34.3.199
Ahn, Ah-Leum, et al. "Non-alcoholic Fatty Liver Disease and Chronic Kidney Disease in Koreans Aged 50 Years or Older." Korean journal of family medicine vol. 34,3 (2013): 199-205. doi: https://doi.org/10.4082/kjfm.2013.34.3.199
Ahn AL, Choi JK, Kim MN, Kim SA, Oh EJ, Kweon HJ, Cho DY. Non-alcoholic Fatty Liver Disease and Chronic Kidney Disease in Koreans Aged 50 Years or Older. Korean J Fam Med. 2013 May;34(3):199-205. doi: 10.4082/kjfm.2013.34.3.199. Epub 2013 May 24. PMID: 23730487; PMCID: PMC3667227.
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Hepatic safety of ambrisentan alone and in combination with tadalafil: a post-hoc analysis of the AMBITION trial.

Pulmonary circulation

Patel KR, Blair CJ, Tislow JD.
PMID: 30124136
Pulm Circ. 2018 Oct-Dec;8(4):2045894018797273. doi: 10.1177/2045894018797273. Epub 2018 Aug 20.

Treatment with endothelin receptor antagonists (ERA) can result in adverse hepatic effects in patients with pulmonary arterial hypertension (PAH). We evaluated the hepatic safety of ambrisentan (ABS), an ERA, used as monotherapy, or with tadalafil (TAD), a phosphodiesterase-5 (PDE5)...

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Patel KR, Blair CJ, Tislow JD. Hepatic safety of ambrisentan alone and in combination with tadalafil: a post-hoc analysis of the AMBITION trial. Pulm Circ. 2018;8(4):2045894018797273doi: 10.1177/2045894018797273.
Patel, K. R., Blair, C. J., & Tislow, J. D. (2018). Hepatic safety of ambrisentan alone and in combination with tadalafil: a post-hoc analysis of the AMBITION trial. Pulmonary circulation, 8(4), 2045894018797273. https://doi.org/10.1177/2045894018797273
Patel, Krishna R, et al. "Hepatic safety of ambrisentan alone and in combination with tadalafil: a post-hoc analysis of the AMBITION trial." Pulmonary circulation vol. 8,4 (2018): 2045894018797273. doi: https://doi.org/10.1177/2045894018797273
Patel KR, Blair CJ, Tislow JD. Hepatic safety of ambrisentan alone and in combination with tadalafil: a post-hoc analysis of the AMBITION trial. Pulm Circ. 2018 Oct-Dec;8(4):2045894018797273. doi: 10.1177/2045894018797273. Epub 2018 Aug 20. PMID: 30124136; PMCID: PMC6122251.
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Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function.

Clinical, cosmetic and investigational dermatology

Al-Eitan LN, Aljamal HA, Alkhatib RQ.
PMID: 30643445
Clin Cosmet Investig Dermatol. 2018 Dec 31;12:11-21. doi: 10.2147/CCID.S190359. eCollection 2019.

BACKGROUND: Sunscreens are one of the most widely used products among cosmetics and personal care products. Recent studies have shown that some of sunscreen formulations may contain toxic, carcinogenic, or even nonallowed chemicals that may affect skin, cells, and...

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Al-Eitan LN, Aljamal HA, Alkhatib RQ. Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function. Clin Cosmet Investig Dermatol. 2018;12:11-21doi: 10.2147/CCID.S190359.
Al-Eitan, L. N., Aljamal, H. A., & Alkhatib, R. Q. (2019). Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function. Clinical, cosmetic and investigational dermatology, 1211-21. https://doi.org/10.2147/CCID.S190359
Al-Eitan, Laith N, et al. "Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function." Clinical, cosmetic and investigational dermatology vol. 12 (2019): 11-21. doi: https://doi.org/10.2147/CCID.S190359
Al-Eitan LN, Aljamal HA, Alkhatib RQ. Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function. Clin Cosmet Investig Dermatol. 2018 Dec 31;12:11-21. doi: 10.2147/CCID.S190359. eCollection 2019. PMID: 30643445; PMCID: PMC6319425.
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TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis .

Frontiers in pharmacology

Wan YM, Wu HM, Li YH, Xu ZY, Yang JH, Liu C, He YF, Wang MJ, Wu XN, Zhang Y.
PMID: 32116692
Front Pharmacol. 2020 Feb 04;11:10. doi: 10.3389/fphar.2020.00010. eCollection 2020.

Tumor necrosis factor (TNF)-α-stimulated protein 6 (TSG-6) is a secreted protein with diverse tissue protective and anti-inflammatory properties. We aimed to investigate its effective in treating mice with alcoholic hepatitis (AH) and the associated mechanisms. AH was induced in...

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Wan YM, Wu HM, Li YH, et al. TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis . Front Pharmacol. 2020;11:10doi: 10.3389/fphar.2020.00010.
Wan, Y. M., Wu, H. M., Li, Y. H., Xu, Z. Y., Yang, J. H., Liu, C., He, Y. F., Wang, M. J., Wu, X. N., & Zhang, Y. (2020). TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis . Frontiers in pharmacology, 1110. https://doi.org/10.3389/fphar.2020.00010
Wan, Yue-Meng, et al. "TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis ." Frontiers in pharmacology vol. 11 (2020): 10. doi: https://doi.org/10.3389/fphar.2020.00010
Wan YM, Wu HM, Li YH, Xu ZY, Yang JH, Liu C, He YF, Wang MJ, Wu XN, Zhang Y. TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis . Front Pharmacol. 2020 Feb 04;11:10. doi: 10.3389/fphar.2020.00010. eCollection 2020. PMID: 32116692; PMCID: PMC7010862.
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Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model.

Journal of ethnopharmacology

Xu Z, Lin S, Tong Z, Chen S, Cao Y, Li Q, Jiang Y, Cai W, Tong Y, Zahra BS, Wang P.
PMID: 34848360
J Ethnopharmacol. 2021 Nov 27;285:114873. doi: 10.1016/j.jep.2021.114873. Epub 2021 Nov 27.

ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicine considers that the etiology and pathogenesis of non-alcoholic fatty liver disease (NAFLD) are related to liver depression and qi stagnation. Saffron and its active ingredient, crocetin (CCT), are used for the treatment of metabolic...

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Xu Z, Lin S, Tong Z, et al. Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. J Ethnopharmacol. 2021;285:114873doi: 10.1016/j.jep.2021.114873.
Xu, Z., Lin, S., Tong, Z., Chen, S., Cao, Y., Li, Q., Jiang, Y., Cai, W., Tong, Y., Zahra, B. S., & Wang, P. (2021). Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. Journal of ethnopharmacology, 285114873. https://doi.org/10.1016/j.jep.2021.114873
Xu, Zijin, et al. "Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model." Journal of ethnopharmacology vol. 285 (2021): 114873. doi: https://doi.org/10.1016/j.jep.2021.114873
Xu Z, Lin S, Tong Z, Chen S, Cao Y, Li Q, Jiang Y, Cai W, Tong Y, Zahra BS, Wang P. Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. J Ethnopharmacol. 2021 Nov 27;285:114873. doi: 10.1016/j.jep.2021.114873. Epub 2021 Nov 27. PMID: 34848360.
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IgG4 subclass and gamma-glutamyl transferase in children with ulcerative colitis with primary sclerosing cholangitis and without sclerosing cholangitis.

Clinical and experimental hepatology

Farahmand F, Ahmadi M, Khodadad A, Najafi M, Fallahi G, Motamed F, Movahedi M, Aghamohammadi A, Rezaei N, Javaherizadeh H.
PMID: 31893239
Clin Exp Hepatol. 2019 Nov;5(4):285-288. doi: 10.5114/ceh.2019.89119. Epub 2019 Oct 17.

AIM OF THE STUDY: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease which could be associated with inflammatory bowel disease (IBD), particularly ulcerative colitis (UC). The aim of this study was to compare GGT and IgG4 levels...

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Farahmand F, Ahmadi M, Khodadad A, et al. IgG4 subclass and gamma-glutamyl transferase in children with ulcerative colitis with primary sclerosing cholangitis and without sclerosing cholangitis. Clin Exp Hepatol. 2019;5(4):285-288doi: 10.5114/ceh.2019.89119.
Farahmand, F., Ahmadi, M., Khodadad, A., Najafi, M., Fallahi, G., Motamed, F., Movahedi, M., Aghamohammadi, A., Rezaei, N., & Javaherizadeh, H. (2019). IgG4 subclass and gamma-glutamyl transferase in children with ulcerative colitis with primary sclerosing cholangitis and without sclerosing cholangitis. Clinical and experimental hepatology, 5(4), 285-288. https://doi.org/10.5114/ceh.2019.89119
Farahmand, Fatemeh, et al. "IgG4 subclass and gamma-glutamyl transferase in children with ulcerative colitis with primary sclerosing cholangitis and without sclerosing cholangitis." Clinical and experimental hepatology vol. 5,4 (2019): 285-288. doi: https://doi.org/10.5114/ceh.2019.89119
Farahmand F, Ahmadi M, Khodadad A, Najafi M, Fallahi G, Motamed F, Movahedi M, Aghamohammadi A, Rezaei N, Javaherizadeh H. IgG4 subclass and gamma-glutamyl transferase in children with ulcerative colitis with primary sclerosing cholangitis and without sclerosing cholangitis. Clin Exp Hepatol. 2019 Nov;5(4):285-288. doi: 10.5114/ceh.2019.89119. Epub 2019 Oct 17. PMID: 31893239; PMCID: PMC6935853.
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Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study.

Journal of stroke

Ruban A, Daya N, Schneider ALC, Gottesman R, Selvin E, Coresh J, Lazo M, Koton S.
PMID: 33053951
J Stroke. 2020 Sep;22(3):357-368. doi: 10.5853/jos.2020.00290. Epub 2020 Sep 29.

BACKGROUND AND PURPOSE: Liver enzymes (aspartate aminotransferase [AST], alanine aminotransferase [ALT], and gamma-glutamyl transpeptidase [GGT]) are glutamate-regulatory enzymes, and higher glutamate levels correlated with worse prognosis of patients with neurotrauma. However, less is known about the association between liver...

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Ruban A, Daya N, Schneider ALC, et al. Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study. J Stroke. 2020;22(3):357-368doi: 10.5853/jos.2020.00290.
Ruban, A., Daya, N., Schneider, A. L. C., Gottesman, R., Selvin, E., Coresh, J., Lazo, M., & Koton, S. (2020). Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study. Journal of stroke, 22(3), 357-368. https://doi.org/10.5853/jos.2020.00290
Ruban, Angela, et al. "Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." Journal of stroke vol. 22,3 (2020): 357-368. doi: https://doi.org/10.5853/jos.2020.00290
Ruban A, Daya N, Schneider ALC, Gottesman R, Selvin E, Coresh J, Lazo M, Koton S. Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study. J Stroke. 2020 Sep;22(3):357-368. doi: 10.5853/jos.2020.00290. Epub 2020 Sep 29. PMID: 33053951; PMCID: PMC7568972.
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Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model.

Journal of ethnopharmacology

Xu Z, Lin S, Tong Z, Chen S, Cao Y, Li Q, Jiang Y, Cai W, Tong Y, Zahra BS, Wang P.
PMID: 34848360
J Ethnopharmacol. 2021 Nov 27;285:114873. doi: 10.1016/j.jep.2021.114873. Epub 2021 Nov 27.

ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicine considers that the etiology and pathogenesis of non-alcoholic fatty liver disease (NAFLD) are related to liver depression and qi stagnation. Saffron and its active ingredient, crocetin (CCT), are used for the treatment of metabolic...

Cite
Xu Z, Lin S, Tong Z, et al. Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. J Ethnopharmacol. 2021;285:114873doi: 10.1016/j.jep.2021.114873.
Xu, Z., Lin, S., Tong, Z., Chen, S., Cao, Y., Li, Q., Jiang, Y., Cai, W., Tong, Y., Zahra, B. S., & Wang, P. (2021). Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. Journal of ethnopharmacology, 285114873. https://doi.org/10.1016/j.jep.2021.114873
Xu, Zijin, et al. "Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model." Journal of ethnopharmacology vol. 285 (2021): 114873. doi: https://doi.org/10.1016/j.jep.2021.114873
Xu Z, Lin S, Tong Z, Chen S, Cao Y, Li Q, Jiang Y, Cai W, Tong Y, Zahra BS, Wang P. Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. J Ethnopharmacol. 2021 Nov 27;285:114873. doi: 10.1016/j.jep.2021.114873. Epub 2021 Nov 27. PMID: 34848360.
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Severe acute interstitial nephritis secondary to minocycline use in an adolescent girl.

SAGE open medical case reports

Sharma K, Geagan N, Tengsupakul S.
PMID: 32742656
SAGE Open Med Case Rep. 2020 Jul 21;8:2050313X20943069. doi: 10.1177/2050313X20943069. eCollection 2020.

Acute interstitial nephritis is an uncommon but classic complication of minocycline therapy for acne. A 14-year-old African American girl was started on oral minocycline for the treatment of acne 6 weeks before presentation. After 4 weeks on minocycline, she...

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Sharma K, Geagan N, Tengsupakul S. Severe acute interstitial nephritis secondary to minocycline use in an adolescent girl. SAGE Open Med Case Rep. 2020;8:2050313X20943069doi: 10.1177/2050313X20943069.
Sharma, K., Geagan, N., & Tengsupakul, S. (2020). Severe acute interstitial nephritis secondary to minocycline use in an adolescent girl. SAGE open medical case reports, 82050313X20943069. https://doi.org/10.1177/2050313X20943069
Sharma, Kamal, et al. "Severe acute interstitial nephritis secondary to minocycline use in an adolescent girl." SAGE open medical case reports vol. 8 (2020): 2050313X20943069. doi: https://doi.org/10.1177/2050313X20943069
Sharma K, Geagan N, Tengsupakul S. Severe acute interstitial nephritis secondary to minocycline use in an adolescent girl. SAGE Open Med Case Rep. 2020 Jul 21;8:2050313X20943069. doi: 10.1177/2050313X20943069. eCollection 2020. PMID: 32742656; PMCID: PMC7375716.
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Showing 1 to 12 of 69 entries