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Showing 13 to 24 of 101 entries
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Antidepressant use among immigrants with depressive disorder living in Finland: A register-based study.

Journal of affective disorders

Kieseppä V, Markkula N, Taipale H, Holm M, Jokela M, Suvisaari J, Tanskanen A, Gissler M, Lehti V.
PMID: 34953922
J Affect Disord. 2021 Dec 22;299:528-535. doi: 10.1016/j.jad.2021.12.071. Epub 2021 Dec 22.

BACKGROUND: The aim of this study was to examine differences in the initiation and discontinuation of antidepressants between immigrants and the Finnish-born population diagnosed with depression in specialized health care.METHODS: The study utilized register-based data, which includes all immigrants...

Acupuncture: A Promising Approach for Comorbid Depression and Insomnia in Perimenopause.

Nature and science of sleep

Zhao FY, Fu QQ, Spencer SJ, Kennedy GA, Conduit R, Zhang WJ, Zheng Z.
PMID: 34675729
Nat Sci Sleep. 2021 Oct 12;13:1823-1863. doi: 10.2147/NSS.S332474. eCollection 2021.

Comorbid depression and insomnia are ubiquitous mental complaints among women going through the perimenopausal stage of life and can result in major decline in quality of life. Antidepressive agents combined with/without hypnotics, and/or hormone therapy are currently the most...

Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression.

Behavioural brain research

Oliveira TQ, Chaves Filho AJM, Jucá PM, Soares MVR, Cunha NL, Vieira CFX, Gadelha Filho CVJ, Viana GA, De Oliveira GMF, Macedo DS, Vasconcelos SMM.
PMID: 34798169
Behav Brain Res. 2021 Nov 16;419:113667. doi: 10.1016/j.bbr.2021.113667. Epub 2021 Nov 16.

Mirtazapine (MIRT) is a multi-target antidepressant used in treatment of severe depression with promising efficacy, but also with important side effects, mainly sedation and weight gain. Thus, the present study aimed to test the effects of the neuroprotective antioxidant...

Physicochemical, Interaction & Topological Descriptors vs. hMAO-A Inhibition of Aplysinopsin Analogs: A Boulevard to the Discovery of Semi-Synthetic Anti-Depression Agents.

Current drug metabolism

Singla RK, Ashraf GM, Ganash M, Bhat G V, Shen B.
PMID: 34779368
Curr Drug Metab. 2021 Oct 15; doi: 10.2174/1389200222666211015155014. Epub 2021 Oct 15.

BACKGROUND: Neurological disorder, depression is the globally 4th leading cause of chronic disabilities in human beings.OBJECTIVE: This study aimed to model a 2D-QSAR equation that can facilitate the researchers to design better aplysinopsin analogs with potent hMAO-A inhibition.METHODS: Aplysinopsin...

Increased Risk of Metabolic Syndrome in Antidepressants Users: A Mini Review.

Frontiers in psychiatry

Gramaglia C, Gambaro E, Bartolomei G, Camera P, Chiarelli-Serra M, Lorenzini L, Zeppegno P.
PMID: 30546325
Front Psychiatry. 2018 Nov 28;9:621. doi: 10.3389/fpsyt.2018.00621. eCollection 2018.

Mounting evidence has shown that the risk of metabolic syndrome (MetS) is substantially overlapping in the diagnostic subgroups of psychiatric disorders. While it is widely acknowledged that patients receiving antipsychotic medications are at higher risk of MetS than antipsychotic-naive...

Long-term depression incidence and associated mortality among African American and White prostate cancer survivors.

Cancer

Parikh RB, Gallo JJ, Wong YN, Robinson KW, Cashy JP, Narayan V, Jayadevappa R, Chhatre S.
PMID: 34061986
Cancer. 2021 Sep 15;127(18):3476-3485. doi: 10.1002/cncr.33656. Epub 2021 Jun 01.

BACKGROUND: Depression is common after a diagnosis of prostate cancer and may contribute to poor outcomes, particularly among African Americans. The authors assessed the incidence and management of depression and its impact on overall mortality among African American and...

The Brugada Type 1 Electrocardiogram and Ventricular Tachycardia With High-Dose Amitriptyline.

JACC. Case reports

Chow JJ, Kaza N, Varnava A.
PMID: 34317492
JACC Case Rep. 2021 Jan 20;3(1):156-161. doi: 10.1016/j.jaccas.2020.11.016. eCollection 2021 Jan.

A 32-year-old woman with anorexia nervosa experienced ventricular tachycardia while on therapeutic-dose amitriptyline despite normal blood tests, imaging, and intracardiac recordings. Electrocardiograms over several years featured the Type 1 Brugada pattern. Careful electrocardiogram monitoring should be made if using...

Synthesis and anticonvulsant activity of various mannich and schiff bases of 1,5-benzodiazepines.

International journal of medicinal chemistry

Pandeya SN, Rajput N.
PMID: 25374684
Int J Med Chem. 2012;2012:237965. doi: 10.1155/2012/237965. Epub 2012 Nov 28.

Benzodiazepines have a various behavioral effects in addition to their anxiolytic action. There is every reason to believe that the BZ/GABA receptor complex is involved in these effects, since GABAmimetic manipulations modify the effect of BZ in tests of...

Activation of the inflammatory response system: A new look at the etiopathogenesis of major depression.

Neuro endocrinology letters

van West D, Maes M.
PMID: 11473226
Neuro Endocrinol Lett. 1999;20(1):11-17.

Major depression is accompanied by various direct and indirect indicators of a moderate activation of the inflammatory response system (IRS). Increased production of proinflammatory cytokines, such as interleukin-1 (IL-1), IL-6 and interferon (IFNgamma), may play a crucial role in...

Perioperative duloxetine as part of a multimodal analgesia regime reduces postoperative pain in lumbar canal stenosis surgery: a randomized, triple blind, and placebo-controlled trial.

The Korean journal of pain

Govil N, Parag K, Arora P, Khandelwal H, Singh A.
PMID: 31888316
Korean J Pain. 2020 Jan 01;33(1):40-47. doi: 10.3344/kjp.2020.33.1.40.

BACKGROUND: Duloxetine is an antidepressant that is also useful in chronic neuropathic and central origin pain. In this study, the role of duloxetine in decreasing acute postoperative pain after lumbar canal stenosis surgery is explored.METHODS: In this single center,...

Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Park JY, Chae S, Kim CS, Kim YJ, Yi HJ, Han E, Joo Y, Hong S, Yun JW, Kim H, Shin KH.
PMID: 31680765
Korean J Physiol Pharmacol. 2019 Nov;23(6):427-448. doi: 10.4196/kjpp.2019.23.6.427. Epub 2019 Oct 24.

Nociceptin/orphanin FQ (N/OFQ) and its receptor, nociceptin opioid peptide (NOP) receptor, are localized in brain areas implicated in depression including the amygdala, bed nucleus of the stria terminalis, habenula, and monoaminergic nuclei in the brain stem. N/OFQ inhibits neuronal...

Treatment of chronic facial pain.

Current treatment options in neurology

Lincoff NS.
PMID: 16343362
Curr Treat Options Neurol. 2006 Jan;8(1):69-79. doi: 10.1007/s11940-996-0025-7.

Facial pain occurs because of damage to the fifth cranial nerve anywhere along its course from its terminal subcutaneous craniofacial branches to the brainstem. Although topical agents may be effective in relieving pain caused by subcutaneous branch damage, systemic...

Showing 13 to 24 of 101 entries