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Showing 13 to 24 of 28 entries
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Antibody Therapeutics in Oncology.

Immunotherapy (Los Angeles, Calif.)

Wold ED, Smider VV, Felding BH.
PMID: 27081677
Immunotherapy (Los Angel). 2016 Mar;2(1). Epub 2016 Feb 01.

One of the newer classes of targeted cancer therapeutics is monoclonal antibodies. Monoclonal antibody therapeutics are a successful and rapidly expanding drug class due to their high specificity, activity, favourable pharmacokinetics, and standardized manufacturing processes. Antibodies are capable of...

From Polyclonal Sera to Recombinant Antibodies: A Review of Immunological Detection of Gluten in Foodstuff.

Foods (Basel, Switzerland)

Garcia-Calvo E, García-García A, Madrid R, Martin R, García T.
PMID: 33396828
Foods. 2020 Dec 30;10(1). doi: 10.3390/foods10010066.

Gluten is the ethanol-soluble protein fraction of cereal endosperms like wheat, rye, and barley. It is widely used in the food industry because of the physical-chemical properties it gives to dough. Nevertheless, there are some gluten-related diseases that are...

Identification of Heteroreceptors Complexes and Signal Transduction Events Using Bioluminescence Resonance Energy Transfer (BRET).

Bio-protocol

Reyes-Resina I, Jiménez J, Navarro G, Franco R.
PMID: 33654881
Bio Protoc. 2019 Oct 05;9(19):e3385. doi: 10.21769/BioProtoc.3385. eCollection 2019 Oct 05.

Detecting protein-protein interactions by co-immunoprecipitation provided a major advancement in the immunology research field. In the G-protein-coupled receptors (GPCRs) research field, colocalization and co-immunoprecipitation were used to detect interactions, but doubts arose due to specificity of the antibodies (monoclonal...

Follicular lymphoma - treatment and prognostic factors.

Revista brasileira de hematologia e hemoterapia

Luminari S, Bellei M, Biasoli I, Federico M.
PMID: 23049385
Rev Bras Hematol Hemoter. 2012;34(1):54-9. doi: 10.5581/1516-8484.20120015.

Follicular lymphoma is the second most frequent non-Hodgkin lymphoma accounting for about 10-20% of all lymphomas in western countries. The median age at diagnosis is 60 years old. The clinical presentation is usually characterized by asymptomatic peripheral adenopathy in...

New Trends in Inflammatory Bowel Disease.

GE Portuguese journal of gastroenterology

Palmela C, Torres J, Cravo M.
PMID: 28868386
GE Port J Gastroenterol. 2015 May 11;22(3):103-111. doi: 10.1016/j.jpge.2015.03.009. eCollection 2015.

Inflammatory bowel disease (IBD) is a chronic idiopathic inflammatory disease of the gastrointestinal (GI) tract. In the past decade a shift in the treatment paradigm of IBD has ensued. The availability of drugs capable of inducing mucosal healing, combined...

Usefulness of fecal calprotectin by monoclonal antibody testing in adult Japanese with inflammatory bowel diseases: a prospective multicenter study.

Intestinal research

Nakamura S, Imaeda H, Nishikawa H, Iimuro M, Matsuura M, Oka H, Oku J, Miyazaki T, Honda H, Watanabe K, Nakase H, Andoh A.
PMID: 30301337
Intest Res. 2018 Oct;16(4):554-562. doi: 10.5217/ir.2018.00027. Epub 2018 Oct 10.

BACKGROUND/AIMS: Noninvasive objective monitoring is advantageous for optimizing treatment strategies in patients inflammatory bowel disease (IBD). Fecal calprotectin (FCP) is superior to traditional biomarkers in terms of assessing the activity in patients with IBD. However, there are the differences...

Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis.

Asia Pacific allergy

Kuo JC, Hawkins CA, Yip D.
PMID: 26539407
Asia Pac Allergy. 2015 Oct;5(4):234-6. doi: 10.5415/apallergy.2015.5.4.234. Epub 2015 Oct 28.

Skin testing has been utilised to determine the culprit allergenic agent in drug reactions. Its application in the setting of hypersensitivity reaction relating to combination chemotherapeutic regimens may help identify the causative drug, allowing drug that is safe to...

Profiling of primary peripheral blood- and monocyte-derived dendritic cells using monoclonal antibodies from the HLDA10 Workshop in Wollongong, Australia.

Clinical & translational immunology

Autenrieth SE, Grimm S, Rittig SM, Grünebach F, Gouttefangeas C, Bühring HJ.
PMID: 26682057
Clin Transl Immunology. 2015 Nov 13;4(11):e50. doi: 10.1038/cti.2015.29. eCollection 2015 Nov.

Dendritic cells (DCs) arise from hematopoietic stem cells and develop into a discrete cellular lineage distinct from other leucocytes. Mainly three phenotypically and functionally distinct DC subsets are described in the human peripheral blood (PB): plasmacytoid DCs (pDCs), which...

Double-bullet radioimmunotargeting therapy in 31 primary liver cancer patients.

World journal of gastroenterology

Wu YD, Zhou DN, Gang YQ, Hu XH, Li ZG, Song XQ, He HP, Yang KZ, Huang BY.
PMID: 27239136
World J Gastroenterol. 1997 Sep 15;3(3):165. doi: 10.3748/wjg.v3.i3.165.

AIM: To observe the effect of double bullet immunotargeting therapy with chemotherapy and internal radiotherapy on primary liver cancer.METHODS: The polyclonal horse antibody against human AFP (anti-AFPAb) and the monoclonal murine antibody against human AFP (anti-AFPMcAb) were used as...

Competitive ELISA.

Methods in molecular biology (Clifton, N.J.)

Makarananda K, Neal GE.
PMID: 23150318
Methods Mol Biol. 1992;10:267-72. doi: 10.1385/0-89603-204-3:267.

Enzyme-linked immunosorbent assay (ELISA) is a very useful technique for the specific and sensitive assay of certain compounds, in which suitable antibodies, monoclonal or polyclonal, to the compounds are available. The technique has found particular application in the monitoring...

Monoclonal and Polyclonal Antibodies Specific to Human Fibromodulin.

Iranian journal of biotechnology

Farahi L, Ghaemimanesh F, Milani S, Razavi SM, Bayat AA, Rabbani H, Akhondi MM.
PMID: 31457049
Iran J Biotechnol. 2019 Jan 11;17(1):e2277. doi: 10.21859/ijb.2277. eCollection 2019 Jan.

BACKGROUND: The unique expression of fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL) has been previously reported. Detecting FMOD in CLL patients using specific anti-FMOD mAbs might provide a promising method in detection, monitoring, and prognosis of CLL.OBJECTIVES:...

Rapid generation of high-level antibodies in vitro and in vivo.

Discovery medicine

Fang J, Jooss K.
PMID: 20704874
Discov Med. 2005 Aug;5(28):367-70.

Extract: During the past decade, important advances in biotechnology include the invention of an array of technologies that have resulted in the generation of monoclonal antibodies with human sequences. These technologies include humanization of mouse antibodies using molecular techniques,...

Showing 13 to 24 of 28 entries