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Showing 253 to 264 of 269 entries
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Responses of oral-microflora-exposed dental pulp to capping with a triple antibiotic paste or calcium hydroxide cement in mouse molars.

Regenerative therapy

Quispe-Salcedo A, Sato T, Matsuyama J, Ida-Yonemochi H, Ohshima H.
PMID: 33426222
Regen Ther. 2020 Oct 29;15:216-225. doi: 10.1016/j.reth.2020.10.001. eCollection 2020 Dec.

INTRODUCTION: Responses of oral-microflora-exposed dental pulp to a triple antibiotic paste (TAP), a mixture of ciprofloxacin, metronidazole, and minocycline in ointment with macrogol and propylene glycol, remain to be fully clarified at the cellular level. This study aimed to...

Door-to-antibiotic Time and In-hospital Mortality of Elder Patients Presenting to Emergency Department with Sepsis; a Cross-Sectional Study.

Archives of academic emergency medicine

Tantarattanapong S, Hemwej T.
PMID: 34223189
Arch Acad Emerg Med. 2021 Jun 11;9(1):e44. doi: 10.22037/aaem.v9i1.1266. eCollection 2021.

INTRODUCTION: The current international sepsis guideline recommends that administration of intravenous broad-spectrum antibiotics should be initiated within 1 hour of emergency department (ED) arrival for sepsis patients. This study aimed to evaluate the association between door-to-antibiotic time and in-hospital...

A minireview of 1,2,3-triazole hybrids with O-heterocycles as leads in medicinal chemistry.

Chemical biology & drug design

Saroha B, Kumar G, Kumar R, Kumari M, Kumar S.
PMID: 34592059
Chem Biol Drug Des. 2021 Sep 30; doi: 10.1111/cbdd.13966. Epub 2021 Sep 30.

Over the past few decades, the dynamic progress in the synthesis and screening of heterocyclic compounds against various targets has made a significant contribution in the field of medicinal chemistry. Among the wide array of heterocyclic compounds, triazole moiety...

Curcumin-meropenem synergy in carbapenem resistant .

Iranian journal of microbiology

Gülen D, Şafak B, Erdal B, Günaydın B.
PMID: 34540173
Iran J Microbiol. 2021 Jun;13(3):345-351. doi: 10.18502/ijm.v13i3.6397.

BACKGROUND AND OBJECTIVES: The frequency of multiple resistant bacterial infections, including carbapenems, is increasing worldwide. As the decrease in treatment options causes difficulties in treatment, interest in new antimicrobials is increasing. One of the promising natural ingredients is curcumin....

A retrospective cohort study assessing acute kidney injury and renal recovery among septic patients empirically treated with vancomycin piperacillin-tazobactam versus vancomycin cefepime.

Internal and emergency medicine

Elliott BP, Tang MM, Madden JA, Markert RJ, Burdette SD, Pleiman CM, Speelmon EC.
PMID: 34089468
Intern Emerg Med. 2021 Jun 05; doi: 10.1007/s11739-021-02772-2. Epub 2021 Jun 05.

Vancomycin plus piperacillin-tazobactam (VPT) is a commonly used antimicrobial regimen for septic patients. VPT is more nephrotoxic than other regimens such as vancomycin plus cefepime (VC) when given over several days. This risk of nephrotoxicity is less clear when...

Timeliness of administration of amoxicillin-clavulanic acid and meropenem in a large tertiary care centre.

International journal of clinical pharmacy

Van Wilder A, Bruyneel L, Decock C, Ten Haaf N, Peetermans WE, Debaveye Y, Vanhaecht K, Spriet I.
PMID: 34138408
Int J Clin Pharm. 2021 Dec;43(6):1651-1659. doi: 10.1007/s11096-021-01297-0. Epub 2021 Jun 17.

Background For amoxicillin-clavulanic acid and meropenem to be effective, concentrations must exceed the minimum inhibitory concentration of infecting pathogens. Objective To retrospectively evaluate time windows between both scheduled prescription and administration and reconstitution-preparation and end of administration of intravenous...

Pediatric intratesticular abscess managed with a testicular sparing approach: A case report.

Urology case reports

Lurz K, Santarelli S, Hager S, Hani AB.
PMID: 34660205
Urol Case Rep. 2021 Sep 30;40:101873. doi: 10.1016/j.eucr.2021.101873. eCollection 2022 Jan.

Intratesticular abscess is a rare finding associated with advanced or untreated epididymo-orchitis, often in immunocompromised patients. Implicated pathogens can be spread hematogenously, by urine reflux in dysfunctional voiders, through aberrant mesonephric duct anatomy, or via a patent processus vaginalis...

Correlation between Previous Antibiotic Exposure and COVID-19 Severity. A Population-Based Cohort Study.

Antibiotics (Basel, Switzerland)

Llor C, Ouchi D, Giner-Soriano M, García-Sangenís A, Bjerrum L, Morros R.
PMID: 34827302
Antibiotics (Basel). 2021 Nov 08;10(11). doi: 10.3390/antibiotics10111364.

We examined the correlation between previous antibiotic exposure and COVID-19 severity using a population-based observational matched cohort study with patient level data obtained for more than 5.8 million people registered in SIDIAP in Catalonia, Spain. We included all patients...

Recovery of antimicrobial susceptibility in methicillin-resistant .

PeerJ

Koike Y, Nishiura H.
PMID: 34221728
PeerJ. 2021 Jun 21;9:e11644. doi: 10.7717/peerj.11644. eCollection 2021.

Anti-methicillin-resistant

Risk of antibiotic treatment failure in premenopausal women with uncomplicated urinary tract infection.

Pharmacoepidemiology and drug safety

Butler AM, Durkin MJ, Keller MR, Ma Y, Dharnidharka VR, Powderly WG, Olsen MA.
PMID: 33783918
Pharmacoepidemiol Drug Saf. 2021 Oct;30(10):1360-1370. doi: 10.1002/pds.5237. Epub 2021 Apr 13.

PURPOSE: Acute uncomplicated urinary tract infections (UTIs) are among the most common indications for antibiotic prescriptions in otherwise healthy women. We compared the risk of treatment failure of antibiotic regimens for outpatient treatment of UTI in real-world practice.METHODS: We...

Bixa orellana L. (Achiote, Annatto) as an antimicrobial agent: A scoping review of its efficiency and technological prospecting.

Journal of ethnopharmacology

Coelho Dos Santos D, Silva Barboza AD, Ribeiro JS, Rodrigues Junior SA, Campos ÂD, Lund RG.
PMID: 34968663
J Ethnopharmacol. 2021 Dec 28;287:114961. doi: 10.1016/j.jep.2021.114961. Epub 2021 Dec 28.

ETHNOPHARMACOLOGICAL RELEVANCE: Bixa orellana L. is reported to have numerous applications in traditional medicine and pharmacological properties such as wound healing, analgesic, hemostatic, and antioxidant activities. Recently, the literature has shown scientific interest of its antimicrobial properties aiming the...

Impact of a 5-year antimicrobial stewardship program focusing on fluoroquinolone prescriptions.

The International journal of pharmacy practice

Pédeboscq S, Issa N, Lahouati M, Labadie A, Pereyre S, Camou F.
PMID: 34355739
Int J Pharm Pract. 2021 Dec 04;29(6):616-621. doi: 10.1093/ijpp/riab047.

OBJECTIVES: Within the context of the wide use of fluoroquinolones (FQs) and the emergence of multidrug-resistant bacteria, French recommendations concerning the appropriate use of systemic FQs in adults were published in 2015. This study assessed the impact of antibiotic...

Showing 253 to 264 of 269 entries