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Showing 25 to 36 of 87 entries
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Comparative activities of compounds of the androsterone-testosterone series.

The Biochemical journal

Deanesly R, Parkes AS.
PMID: 16746019
Biochem J. 1936 Feb;30(2):291-303. doi: 10.1042/bj0300291.

No abstract available.

Effects of thyroid status and thyrostatic drugs on hepatic glucuronidation of lodothyronines and other substrates in rats : Induction of phenol UDP-glucuronyltransferase by methimazole.

Endocrine

Visser TJ, Kaptein E, Gijzel A, de Herder WW, Cannon ML, Bonthuis F, de Greef WJ.
PMID: 21153295
Endocrine. 1996 Feb;4(1):79-85. doi: 10.1007/BF02738878.

Glucuronidation of iodothyronines in rat liver is catalyzed by at least three UDP-glucuronyltransferases (UGTs): bilirubin UGT, phenol UGT, and androsterone UGT. Bilirubin and phenol UGT activities are regulated by thyroid hormone, but the effect of thyroid status on hepatic...

An amperometric enzyme electrode for the determination of 3alpha-hydroxysteroids.

Talanta

Teodorczyk M, Purdyt WC.
PMID: 18965022
Talanta. 1990 Aug;37(8):795-800. doi: 10.1016/0039-9140(90)80121-u.

An enzyme electrode for quantifying the total content of 3alpha-hydroxysteroids is described. 3alpha-Hydroxysteroid dehydrogenase (E.C. 1.1.1.50) was immobilized on the surface of glassy-carbon and low-temperature isotropic-carbon electrodes by intermolecular cross-linking with bovine serum albumin and glutaraldehyde. The effects of...

Antitumour effect of a- and d- lactam androgen nitrogen mustards on non-small cell lung carcinoma.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology

Trafalis DT, Camoutsis C, Dalezis P, Papageorgiou A, Kontos M, Karamanakos P, Giannakos G, Athanassiou AE.
PMID: 17415826
J BUON. 2004 Jul-Sep;9(3):275-82.

PURPOSE: We tested 3 alkylating esters of D-lactam androsterone, 3 alkylating esters of A-lactam testosterone and the alkylating nitrogen mustard components of these esters, for antineoplastic activity on non-small cell lung carcinoma (NSCLC) in vitro and in vivo.MATERIALS AND...

Effects of steroids and steroid synthesis inhibitors on fecundity ofSchistosoma mansoni in vitro.

Journal of chemical ecology

Morrison DD, Vande Waa EA, Bennett JL.
PMID: 24305903
J Chem Ecol. 1986 Aug;12(8):1901-8. doi: 10.1007/BF01022391.

In vitro egg production bySchistosoma mansoni was examined following a 72-hr incubation period in the presence of various steroids, steroid precursors, or steroid synthesis inhibitors. Mevinolin, an inhibitor of cholesterol biosynthesis, significantly decreased egg production at 10(-6) M. However,...

Human axillary extracts: Analysis of compounds from samples which influence menstrual timing.

Journal of chemical ecology

Preti G, Cutler WB, Christensen CM, Lawley H, Huggins GR, Garcia CR.
PMID: 24302040
J Chem Ecol. 1987 Apr;13(4):717-31. doi: 10.1007/BF01020154.

Previous studies have shown that menstrual cycle length and fertility are affected by a regular pattern of either: (1) intimate contact with men; or (2) contact with extracts from male axillary secretions; and (3) the axillary extracts of women....

Erratum to: DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.

Psychopharmacology

Ben Dor R, Marx CE, Shampine LJ, Rubinow DR, Schmidt PJ.
PMID: 26271211
Psychopharmacology (Berl). 2015 Oct;232(19):3683. doi: 10.1007/s00213-015-4046-3.

No abstract available.

Altered levels of circulating GABAergic 5α/β-reduced pregnane and androstane steroids in schizophrenic men.

Hormone molecular biology and clinical investigation

Bicikova M, Hill M, Ripova D, Mohr P.
PMID: 25961259
Horm Mol Biol Clin Investig. 2011 May 01;6(2):227-30. doi: 10.1515/HMBCI.2010.083.

The role of GABAergic pathways in the pathophysiology of schizophrenia is generally accepted. Therefore, the information concerning alterations of the steroid metabolome associated with the disease and/or its treatment is of interest with regard to the pathophysiology of the...

Ultrasensitive enzyme-linked immunosorbent assay (ELISA) of proteins by combination with the thio-NAD cycling method.

Biophysics (Nagoya-shi, Japan)

Watabe S, Kodama H, Kaneda M, Morikawa M, Nakaishi K, Yoshimura T, Iwai A, Miura T, Ito E.
PMID: 27493498
Biophysics (Nagoya-shi). 2014 Sep 05;10:49-54. doi: 10.2142/biophysics.10.49. eCollection 2014.

An ultrasensitive method for the determination of proteins is described that combines an enzyme-linked immunosorbent assay (ELISA) and a thionicotinamide-adenine dinucleotide (thio-NAD) cycling method. A sandwich method using a primary and a secondary antibody for antigens is employed in...

Sensitive detection of testosterone and testosterone prohormone administrations based on urinary concentrations and carbon isotope ratios of androsterone and etiocholanolone.

Drug testing and analysis

Piper T, Haenelt N, Fusshöller G, Geyer H, Thevis M.
PMID: 34648228
Drug Test Anal. 2021 Oct 14; doi: 10.1002/dta.3168. Epub 2021 Oct 14.

The testing strategy for the detection of testosterone (T) or T-prohormones is based on the longitudinal evaluation of urinary steroid concentrations accompanied by subsequent isotope ratio mass spectrometry (IRMS)-based confirmation of samples showing atypical concentrations or concentration ratios. In...

Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport.

Drug testing and analysis

Mazzarino M, Comunità F, de la Torre X, Molaioni F, Botrè F.
PMID: 34212529
Drug Test Anal. 2021 Oct;13(10):1712-1726. doi: 10.1002/dta.3121. Epub 2021 Jul 14.

This article reports the results obtained from the investigation of the influence of miconazole administration on the physiological fluctuation of the markers of the steroid profile included in the "steroidal module" of the Athlete Biological Passport. Urines collected from...

Simultaneous measurement of 18 steroids in human and mouse serum by liquid chromatography-mass spectrometry without derivatization to profile the classical and alternate pathways of androgen synthesis and metabolism.

Clinical mass spectrometry (Del Mar, Calif.)

Desai R, Harwood DT, Handelsman DJ.
PMID: 34841072
Clin Mass Spectrom. 2019 Jan 06;11:42-51. doi: 10.1016/j.clinms.2018.12.003. eCollection 2019 Jan.

BACKGROUND: The recently identified alternate, or backdoor, pathway of DHT synthesis provides important novel information on androgen biosynthesis beyond the classical pathway. We report a rapid and versatile liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to simultaneously and accurately quantify...

Showing 25 to 36 of 87 entries