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Showing 25 to 36 of 443 entries
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WITHDRAWN: Sensitive and Accurate Simultaneous Measurement of Estrone, Estradiol, Dehydroepiandrosterone, Androst-5-ene-3 beta, 17 beta diol, Androstenedione, Testosterone and Dihydrotestosterone in Postmenopausal Women Serum by a Robust LC-MS/MS Validated Assay using a Single Sample Preparation Method.

Steroids

Ke Y, Bertin J, Gonthier R, Simard JN, Labrie F.
PMID: 25159106
Steroids. 2014 Aug 23; doi: 10.1016/j.steroids.2014.08.001. Epub 2014 Aug 23.

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

Congenital Adrenal Hyperplasia due to 17-alpha-hydoxylase/17,20-lyase Deficiency Presenting with Hypertension and Pseudohermaphroditism: First Case Report from Oman.

Oman medical journal

Mula-Abed WA, Pambinezhuth FB, Al-Kindi MK, Al-Busaidi NB, Al-Muslahi HN, Al-Lamki MA.
PMID: 24498484
Oman Med J. 2014 Jan;29(1):55-9. doi: 10.5001/omj.2014.12.

This is the first report of congenital adrenal hyperplasia (CAH) due to combined 17α-hydroxylase/17,20 lyase deficiency in an Omani patient who was initially treated for many years as a case of hypertension. CAH is an uncommon disorder that results...

Transformation of steroids by axillary coryneform bacteria.

International journal of cosmetic science

Gower DB, Nixon A, Jackman PJ, Mallett AI.
PMID: 19457213
Int J Cosmet Sci. 1986 Aug;8(4):149-58. doi: 10.1111/j.1467-2494.1986.tb00443.x.

Synopsis The contribution made by the apocrine glands to body odour has been discussed. In particular, the role of odorous steroids, such as 5alpha-androst-16-en-3-one (5alpha-A), and their formation by axillary bacteria, has been explored. Isotopically labelled testosterone was incubated...

Detrimental effects of endogenous oestrogens on primary acute myocardial infarction among postmenopausal women.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Dong M, Guo F, Yang J, Liu S, Tao Z, Fang Y, Zhang C, Li J, Li G.
PMID: 23055054
Neth Heart J. 2013 Apr;21(4):175-80. doi: 10.1007/s12471-012-0323-5.

OBJECTIVE: Traditionally, oestrogens were considered to be protective for the cardiovascular system for premenopausal women. Therefore, we conducted a retrospective case-control study to examine the association between endogenous oestrogens and acute myocardial infarction (AMI) risk among postmenopausal women.METHODS: A...

Amniotic Fluid INSL3 Measured During the Critical Time Window in Human Pregnancy Relates to Cryptorchidism, Hypospadias, and Phthalate Load: A Large Case-Control Study.

Frontiers in physiology

Anand-Ivell R, Cohen A, Nørgaard-Pedersen B, Jönsson BAG, Bonde JP, Hougaard DM, Lindh CH, Toft G, Lindhard MS, Ivell R.
PMID: 29740335
Front Physiol. 2018 Apr 24;9:406. doi: 10.3389/fphys.2018.00406. eCollection 2018.

The period of the first to second trimester transition in human pregnancy represents a sensitive window for fetal organogenesis, particularly in regard to the development of the male reproductive system. This is a time of relative analytical inaccessibility. We...

Serum Steroid Ratio Profiles in Prostate Cancer: A New Diagnostic Tool Toward a Personalized Medicine Approach.

Frontiers in endocrinology

Albini A, Bruno A, Bassani B, D'Ambrosio G, Pelosi G, Consonni P, Castellani L, Conti M, Cristoni S, Noonan DM.
PMID: 29674995
Front Endocrinol (Lausanne). 2018 Apr 05;9:110. doi: 10.3389/fendo.2018.00110. eCollection 2018.

BACKGROUND: Serum steroids are crucial molecules altered in prostate cancer (PCa). Mass spectrometry (MS) is currently the elected technology for the analysis of steroids in diverse biological samples. Steroids have complex biological pathways and stoichiometry and it is important...

Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system.

Research and reports in urology

Pais P, Villar A, Rull S.
PMID: 27186566
Res Rep Urol. 2016 Apr 21;8:41-9. doi: 10.2147/RRU.S96576. eCollection 2016.

BACKGROUND: The nicotinamide adenine dinucleotide phosphate-dependent membrane protein 5α-reductase catalyses the conversion of testosterone to the most potent androgen - 5α-dihydrotestosterone. Two 5α-reductase isoenzymes are expressed in humans: type I and type II. The latter is found primarily in...

Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase.

Frontiers in pharmacology

Udhane SS, Parween S, Kagawa N, Pandey AV.
PMID: 28970799
Front Pharmacol. 2017 Aug 25;8:580. doi: 10.3389/fphar.2017.00580. eCollection 2017.

All cytochromes P450s in the endoplasmic reticulum rely on P450 oxidoreductase (POR) for their catalytic activities. Mutations in POR cause metabolic disorders of steroid hormone biosynthesis and affect certain drug metabolizing P450 activities. We studied mutations A115V, T142A, Q153R...

Sensitivity of ovarian cancer cells to acetaminophen reveals biological pathways that affect patient survival.

Molecular and clinical oncology

Bush SH, Tollin S, Marchion DC, Xiong Y, Abbasi F, Ramirez IJ, Zgheib NB, Boac B, Judson PL, Chon HS, Wenham RM, Apte SM, Cubitt CL, Berglund AE, Havrilesky LJ, Lancaster JM.
PMID: 26998291
Mol Clin Oncol. 2016 Mar;4(3):399-404. doi: 10.3892/mco.2016.725. Epub 2016 Jan 07.

Experimental and epidemiological data support the potential activity of acetaminophen against ovarian cancer (OVCA). In this study, we sought to confirm the activity of acetaminophen in OVCA cell lines and to investigate the molecular basis of response. A total...

Prediction of Responsiveness to Clomiphene Citrate in Infertile Women with PCOS.

Journal of reproduction & infertility

Sachdeva G, Gainder S, Suri V, Sachdeva N, Chopra S.
PMID: 31423417
J Reprod Infertil. 2019 Jul-Sep;20(3):143-150.

BACKGROUND: The purpose of the study was to evaluate the role of clinical, metabolic, hormonal and ultrasound features of women with PCOS in predicting the response to clomiphene citrate in treatment of infertility.METHODS: A prospective observational study was done...

Women with Polycystic Ovary Syndrome and Risk of Cardiovascular Disease.

Journal of medical biochemistry

Blagojevic IP, Eror T, Pelivanovic J, Jelic S, Kotur-Stevuljevic J, Ignjatovic S.
PMID: 30568543
J Med Biochem. 2017 Jul 14;36(3):259-269. doi: 10.1515/jomb-2017-0020. eCollection 2017 Sep.

BACKGROUND: Polycystic ovary syndrome (PCOS) is associated with reproductive and metabolic abnormalities. The aim of this study was to analyse risk of cardiovascular disease (CVD) in PCOS, to define individual risk factors and assess their ability to predict risk.METHODS:...

Androstenedione changes steroidogenic activity of SGBS cells.

Endocrine connections

Ernst J, Gert K, Kraus FB, Rolle-Kampczyk UE, Wabitsch M, Dehghani F, Schaedlich K.
PMID: 32580160
Endocr Connect. 2020 Jul;9(7):587-598. doi: 10.1530/EC-19-0549.

The rapid increase of obesity during the last decades and its future prospects are alarming. Besides the general discussed causes of obesity, the 'Developmental Origins of Health and Disease' (DOHaD) hypothesis received more attention in recent years. This hypothesis...

Showing 25 to 36 of 443 entries