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Showing 1705 to 1716 of 1720 entries
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Distribution of androgen receptor mRNA in the prepubertal male and female mouse brain.

Journal of neuroendocrinology

Cara AL, Henson EL, Beekly BG, Elias CF.
PMID: 34866263
J Neuroendocrinol. 2021 Dec;33(12):e13063. doi: 10.1111/jne.13063. Epub 2021 Dec 05.

Androgens are steroid hormones that play a critical role in brain development and sexual maturation by acting upon both androgen receptors (AR) and estrogen receptors (ERα/β) after aromatization. The contribution of estrogens from aromatized androgens in brain development and...

Epigenetics suggests new perspectives for the treatment of polycystic ovary syndrome: Transgenerational effect of fetal exposure to Antimüllerian Hormone.

Annales d'endocrinologie

Pugeat M, Dewailly D.
PMID: 33839124
Ann Endocrinol (Paris). 2021 Apr;82(2):71-73. doi: 10.1016/j.ando.2021.04.001. Epub 2021 Apr 08.

No abstract available.

Relationships between avian malaria resilience and corticosterone, testosterone and prolactin in a Hawaiian songbird.

General and comparative endocrinology

Names GR, Krause JS, Schultz EM, Angelier F, Parenteau C, Ribout C, Hahn TP, Wingfield JC.
PMID: 33862049
Gen Comp Endocrinol. 2021 Jul 01;308:113784. doi: 10.1016/j.ygcen.2021.113784. Epub 2021 Apr 20.

Glucocorticoids, androgens, and prolactin regulate metabolism and reproduction, but they also play critical roles in immunomodulation. Since the introduction of avian malaria to Hawaii a century ago, low elevation populations of the Hawaii Amakihi (Chlorodrepanis virens) that have experienced...

Androgen Effects on the Adrenergic System of the Vascular, Airway, and Cardiac Myocytes and Their Relevance in Pathological Processes.

International journal of endocrinology

Carbajal-García A, Reyes-García J, Montaño LM.
PMID: 33273918
Int J Endocrinol. 2020 Nov 12;2020:8849641. doi: 10.1155/2020/8849641. eCollection 2020.

INTRODUCTION: Androgen signaling comprises nongenomic and genomic pathways. Nongenomic actions are not related to the binding of the androgen receptor (AR) and occur rapidly. The genomic effects implicate the binding to a cytosolic AR, leading to protein synthesis. Both...

Two Foxo1 homologues in the orange-spotted grouper Epinephelus coioides: sequences, expression, and possible involvement in the activation of cyp19a1a expression in the ovary.

Fish physiology and biochemistry

Ning Y, Fan M, Liu Q, Lu H, Qian S, Cui X, Meng F, Li X, Xu X, Sun S, Zhang Y, Zhang L, Zhang W.
PMID: 34417918
Fish Physiol Biochem. 2021 Oct;47(5):1597-1610. doi: 10.1007/s10695-021-01002-y. Epub 2021 Aug 21.

Foxo1, a member of Foxo transcription factor family, is involved in a number of physiological processes including metabolism, cell cycle progression, aging, and apoptosis. In the ovarian granulosa cell of mouse, Foxo1 is implicated to inhibit the expression of...

Nonalcoholic Fatty Liver Disease in Women and Girls With Polycystic Ovary Syndrome.

The Journal of clinical endocrinology and metabolism

Falzarano C, Lofton T, Osei-Ntansah A, Oliver T, Southward T, Stewart S, Andrisse S.
PMID: 34491336
J Clin Endocrinol Metab. 2022 Jan 01;107(1):258-272. doi: 10.1210/clinem/dgab658.

CONTEXT: Nonalcoholic fatty liver disease (NAFLD) describes a spectrum of liver damage due to excessive hepatic lipid accumulation. Recent research has demonstrated a high prevalence of NAFLD in women with polycystic ovary syndrome (PCOS).RESULTS: Strong associations independent of body...

Effect of androgens on Sertoli cell maturation in human testis from birth to puberty.

Basic and clinical andrology

Lapoirie M, Dijoud F, Lejeune H, Plotton I.
PMID: 34906089
Basic Clin Androl. 2021 Dec 14;31(1):31. doi: 10.1186/s12610-021-00150-8.

BACKGROUND: Androgens are well known to be necessary for spermatogenesis. The purpose of this study was to determine Sertoli cell responsiveness to androgens according to age from birth to puberty.RESULTS: Testicular tissue samples were studied in a population of...

Effect of chronic intracerebroventricular administration of an aromatase inhibitor on the expression of socio-sexual behaviors in male Japanese quail.

Behavioural brain research

Court L, Balthazart J, Ball GF, Cornil CA.
PMID: 33901434
Behav Brain Res. 2021 Jul 23;410:113315. doi: 10.1016/j.bbr.2021.113315. Epub 2021 Apr 24.

Aromatase converts androgens into estrogens in the brain of vertebrates including humans. This enzyme is also expressed in other tissues where its action may result in negative effects on human health (e.g., promotion of tumor growth). To prevent these...

Glucocorticoids and Androgens Protect From Gastric Metaplasia by Suppressing Group 2 Innate Lymphoid Cell Activation.

Gastroenterology

Busada JT, Peterson KN, Khadka S, Xu X, Oakley RH, Cook DN, Cidlowski JA.
PMID: 33971182
Gastroenterology. 2021 Aug;161(2):637-652.e4. doi: 10.1053/j.gastro.2021.04.075. Epub 2021 May 07.

BACKGROUND & AIMS: The immune compartment is critical for maintaining tissue homeostasis. A weak immune response increases susceptibility to infection, but immune hyperactivation causes tissue damage, and chronic inflammation may lead to cancer development. In the stomach, inflammation damages...

Dihydrotestosterone Induces Chemo-Resistance of Triple-Negative Breast MDA-MB-231 Cancer Cells Towards Doxorubicin Independent of ABCG2 and miR-328-3p.

Current molecular pharmacology

Al-Momany B, Hammad H, Ahram M.
PMID: 34061013
Curr Mol Pharmacol. 2021;14(5):860-870. doi: 10.2174/1874467214666210531170355.

BACKGROUND: Androgens potentially have an important role in the biology of breast cancer, particularly triple-negative breast cancer (TNBC). Androgen receptor (AR) may offer a novel therapeutic strategy, including the use of microRNA (miRNA) molecules. We have previously shown that...

Brightened body coloration in female guppies (Poecilia reticulata) serves as an in vivo biomarker for environmental androgens: The example of 17β-trenbolone.

Ecotoxicology and environmental safety

Zhang S, Tian H, Sun Y, Li X, Wang W, Ru S.
PMID: 34450427
Ecotoxicol Environ Saf. 2021 Aug 25;224:112698. doi: 10.1016/j.ecoenv.2021.112698. Epub 2021 Aug 25.

In vivo testing systems for environmental androgens are scarce. The aim of this study was to evaluate the potential of male-specific brightened body coloration in female guppies (Poecilia reticulata) to serve as an in vivo biomarker of environmental androgens...

Association of urinary sex steroid hormones with urinary calcium, oxalate and citrate excretion in kidney stone formers.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Fuster DG, Morard GA, Schneider L, Mattmann C, Lüthi D, Vogt B, Dhayat NA.
PMID: 33295624
Nephrol Dial Transplant. 2020 Dec 09; doi: 10.1093/ndt/gfaa360. Epub 2020 Dec 09.

BACKGROUND: Sex-specific differences in nephrolithiasis with respect to both distribution of prevalence and stone composition are widely described and may be influenced by sex hormones.METHODS: We conducted a cross-sectional analysis of the relationship between 24-hour urinary sex hormone metabolites...

Showing 1705 to 1716 of 1720 entries