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Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer.

Bulletin of mathematical biology

Pasetto S, Enderling H, Gatenby RA, Brady-Nicholls R.
PMID: 34797430
Bull Math Biol. 2021 Nov 19;84(1):2. doi: 10.1007/s11538-021-00953-w.

The prostate is an exocrine gland of the male reproductive system dependent on androgens (testosterone and dihydrotestosterone) for development and maintenance. First-line therapy for prostate cancer includes androgen deprivation therapy (ADT), depriving both the normal and malignant prostate cells...

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Pasetto S, Enderling H, Gatenby RA, et al. Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bull Math Biol. 2021;84(1):2doi: 10.1007/s11538-021-00953-w.
Pasetto, S., Enderling, H., Gatenby, R. A., & Brady-Nicholls, R. (2021). Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bulletin of mathematical biology, 84(1), 2. https://doi.org/10.1007/s11538-021-00953-w
Pasetto, S, et al. "Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer." Bulletin of mathematical biology vol. 84,1 (2021): 2. doi: https://doi.org/10.1007/s11538-021-00953-w
Pasetto S, Enderling H, Gatenby RA, Brady-Nicholls R. Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bull Math Biol. 2021 Nov 19;84(1):2. doi: 10.1007/s11538-021-00953-w. PMID: 34797430; PMCID: PMC8604892.
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Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis.

Seminars in cell & developmental biology

Cooke PS, Walker WH.
PMID: 34119408
Semin Cell Dev Biol. 2022 Jan;121:71-81. doi: 10.1016/j.semcdb.2021.05.032. Epub 2021 Jun 09.

Signaling by androgens through androgen receptor (AR) is essential to complete spermatogenesis in the testis. Similarly, loss of the main estrogen receptor, estrogen receptor 1 (ESR1; also known as ERα), results in male infertility, due in part to indirect...

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Cooke PS, Walker WH. Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis. Semin Cell Dev Biol. 2021;121:71-81doi: 10.1016/j.semcdb.2021.05.032.
Cooke, P. S., & Walker, W. H. (2022). Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis. Seminars in cell & developmental biology, 12171-81. https://doi.org/10.1016/j.semcdb.2021.05.032
Cooke, Paul S, and Walker, William H. "Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis." Seminars in cell & developmental biology vol. 121 (2022): 71-81. doi: https://doi.org/10.1016/j.semcdb.2021.05.032
Cooke PS, Walker WH. Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis. Semin Cell Dev Biol. 2022 Jan;121:71-81. doi: 10.1016/j.semcdb.2021.05.032. Epub 2021 Jun 09. PMID: 34119408.
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Androgens in prostate cancer: A tale that never ends.

Cancer letters

Hou Z, Huang S, Li Z.
PMID: 34052327
Cancer Lett. 2021 Sep 28;516:1-12. doi: 10.1016/j.canlet.2021.04.010. Epub 2021 May 28.

Androgens play an essential role in prostate cancer. Clinical treatments that target steroidogenesis and the androgen receptor (AR) successfully postpone disease progression. Abiraterone and enzalutamide, the next-generation androgen receptor pathway inhibitors (ARPI), emphasize the function of the androgen-AR axis...

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Hou Z, Huang S, Li Z. Androgens in prostate cancer: A tale that never ends. Cancer Lett. 2021;516:1-12doi: 10.1016/j.canlet.2021.04.010.
Hou, Z., Huang, S., & Li, Z. (2021). Androgens in prostate cancer: A tale that never ends. Cancer letters, 5161-12. https://doi.org/10.1016/j.canlet.2021.04.010
Hou, Zemin, et al. "Androgens in prostate cancer: A tale that never ends." Cancer letters vol. 516 (2021): 1-12. doi: https://doi.org/10.1016/j.canlet.2021.04.010
Hou Z, Huang S, Li Z. Androgens in prostate cancer: A tale that never ends. Cancer Lett. 2021 Sep 28;516:1-12. doi: 10.1016/j.canlet.2021.04.010. Epub 2021 May 28. PMID: 34052327.
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Androgen and Luteinizing Hormone Stimulate the Function of Rat Immature Leydig Cells Through Different Transcription Signals.

Frontiers in endocrinology

Li X, Zhu Q, Wen Z, Yuan K, Su Z, Wang Y, Zhong Y, Ge RS.
PMID: 33815270
Front Endocrinol (Lausanne). 2021 Mar 17;12:599149. doi: 10.3389/fendo.2021.599149. eCollection 2021.

The function of immature Leydig cells is regulated by hormones, such as androgen and luteinizing hormone (LH). However, the regulation of this process is still unclear. The objective of this study was to determine whether luteinizing hormone (LH) or...

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Li X, Zhu Q, Wen Z, et al. Androgen and Luteinizing Hormone Stimulate the Function of Rat Immature Leydig Cells Through Different Transcription Signals. Front Endocrinol (Lausanne). 2021;12:599149doi: 10.3389/fendo.2021.599149.
Li, X., Zhu, Q., Wen, Z., Yuan, K., Su, Z., Wang, Y., Zhong, Y., & Ge, R. S. (2021). Androgen and Luteinizing Hormone Stimulate the Function of Rat Immature Leydig Cells Through Different Transcription Signals. Frontiers in endocrinology, 12599149. https://doi.org/10.3389/fendo.2021.599149
Li, Xiaoheng, et al. "Androgen and Luteinizing Hormone Stimulate the Function of Rat Immature Leydig Cells Through Different Transcription Signals." Frontiers in endocrinology vol. 12 (2021): 599149. doi: https://doi.org/10.3389/fendo.2021.599149
Li X, Zhu Q, Wen Z, Yuan K, Su Z, Wang Y, Zhong Y, Ge RS. Androgen and Luteinizing Hormone Stimulate the Function of Rat Immature Leydig Cells Through Different Transcription Signals. Front Endocrinol (Lausanne). 2021 Mar 17;12:599149. doi: 10.3389/fendo.2021.599149. eCollection 2021. PMID: 33815270; PMCID: PMC8011569.
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Anti-androgen for myoepithelial tumor: a potent therapy yet a potential misleader.

Anti-cancer drugs

Hijab A, Taha T, Charas T, Bar-Sela G, Stein P, Agbarya A.
PMID: 34387605
Anticancer Drugs. 2021 Aug 11; doi: 10.1097/CAD.0000000000001175. Epub 2021 Aug 11.

Myoepithelial tumor is a rare form of cancer, mainly arising from the salivary glands and extremities. Due to its rarity, no formal treatment guidelines exist. Here we report a case of a male patient diagnosed with metastatic myoepithelial tumor...

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Hijab A, Taha T, Charas T, et al. Anti-androgen for myoepithelial tumor: a potent therapy yet a potential misleader. Anticancer Drugs. 2021;doi: 10.1097/CAD.0000000000001175.
Hijab, A., Taha, T., Charas, T., Bar-Sela, G., Stein, P., & Agbarya, A. (2021). Anti-androgen for myoepithelial tumor: a potent therapy yet a potential misleader. Anti-cancer drugs, . https://doi.org/10.1097/CAD.0000000000001175
Hijab, Adham, et al. "Anti-androgen for myoepithelial tumor: a potent therapy yet a potential misleader." Anti-cancer drugs vol. (2021). doi: https://doi.org/10.1097/CAD.0000000000001175
Hijab A, Taha T, Charas T, Bar-Sela G, Stein P, Agbarya A. Anti-androgen for myoepithelial tumor: a potent therapy yet a potential misleader. Anticancer Drugs. 2021 Aug 11; doi: 10.1097/CAD.0000000000001175. Epub 2021 Aug 11. PMID: 34387605.
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Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer.

Bulletin of mathematical biology

Pasetto S, Enderling H, Gatenby RA, Brady-Nicholls R.
PMID: 34797430
Bull Math Biol. 2021 Nov 19;84(1):2. doi: 10.1007/s11538-021-00953-w.

The prostate is an exocrine gland of the male reproductive system dependent on androgens (testosterone and dihydrotestosterone) for development and maintenance. First-line therapy for prostate cancer includes androgen deprivation therapy (ADT), depriving both the normal and malignant prostate cells...

Cite
Pasetto S, Enderling H, Gatenby RA, et al. Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bull Math Biol. 2021;84(1):2doi: 10.1007/s11538-021-00953-w.
Pasetto, S., Enderling, H., Gatenby, R. A., & Brady-Nicholls, R. (2021). Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bulletin of mathematical biology, 84(1), 2. https://doi.org/10.1007/s11538-021-00953-w
Pasetto, S, et al. "Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer." Bulletin of mathematical biology vol. 84,1 (2021): 2. doi: https://doi.org/10.1007/s11538-021-00953-w
Pasetto S, Enderling H, Gatenby RA, Brady-Nicholls R. Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bull Math Biol. 2021 Nov 19;84(1):2. doi: 10.1007/s11538-021-00953-w. PMID: 34797430; PMCID: PMC8604892.
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Cutibacterium acnes: Much ado about maybe nothing much.

Experimental dermatology

van Steensel MAM, Goh BC.
PMID: 34009698
Exp Dermatol. 2021 Oct;30(10):1471-1476. doi: 10.1111/exd.14394. Epub 2021 Jun 09.

Cutibacterium acnes (also known as Propionibacterium acnes) has long been implicated in the pathogenesis of acne, inspiring both therapeutic and personal care approaches aiming to control the disease by controlling the bacterium. The purported association has made people with...

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van Steensel MAM, Goh BC. Cutibacterium acnes: Much ado about maybe nothing much. Exp Dermatol. 2021;30(10):1471-1476doi: 10.1111/exd.14394.
van Steensel, M. A. M., & Goh, B. C. (2021). Cutibacterium acnes: Much ado about maybe nothing much. Experimental dermatology, 30(10), 1471-1476. https://doi.org/10.1111/exd.14394
van Steensel, Maurice A M, and Goh, Boon Chong. "Cutibacterium acnes: Much ado about maybe nothing much." Experimental dermatology vol. 30,10 (2021): 1471-1476. doi: https://doi.org/10.1111/exd.14394
van Steensel MAM, Goh BC. Cutibacterium acnes: Much ado about maybe nothing much. Exp Dermatol. 2021 Oct;30(10):1471-1476. doi: 10.1111/exd.14394. Epub 2021 Jun 09. PMID: 34009698.
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The Association Between Dietary Inflammatory Index and Sex Hormones Among Postmenopausal Women in the US.

Frontiers in endocrinology

Chen WY, Fu YP, Zhong W, Zhou M.
PMID: 35002960
Front Endocrinol (Lausanne). 2021 Dec 21;12:771565. doi: 10.3389/fendo.2021.771565. eCollection 2021.

AIMS: Diet has been found to have an important effect on sex hormones. The effect of diet-induced inflammation on sex hormones has not been studied in detail among women. Therefore, we aimed to investigate the association between energy-adjusted dietary...

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Chen WY, Fu YP, Zhong W, et al. The Association Between Dietary Inflammatory Index and Sex Hormones Among Postmenopausal Women in the US. Front Endocrinol (Lausanne). 2021;12:771565doi: 10.3389/fendo.2021.771565.
Chen, W. Y., Fu, Y. P., Zhong, W., & Zhou, M. (2021). The Association Between Dietary Inflammatory Index and Sex Hormones Among Postmenopausal Women in the US. Frontiers in endocrinology, 12771565. https://doi.org/10.3389/fendo.2021.771565
Chen, Wen-Yu, et al. "The Association Between Dietary Inflammatory Index and Sex Hormones Among Postmenopausal Women in the US." Frontiers in endocrinology vol. 12 (2021): 771565. doi: https://doi.org/10.3389/fendo.2021.771565
Chen WY, Fu YP, Zhong W, Zhou M. The Association Between Dietary Inflammatory Index and Sex Hormones Among Postmenopausal Women in the US. Front Endocrinol (Lausanne). 2021 Dec 21;12:771565. doi: 10.3389/fendo.2021.771565. eCollection 2021. PMID: 35002960; PMCID: PMC8728879.
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Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes.

European review for medical and pharmacological sciences

Kiani AK, Mor M, Bernini A, Fulcheri E, Michelini S, Herbst KL, Buffelli F, Belgrado JP, Kaftalli J, Stuppia L, Dautaj A, Dhuli K, Guda T, Manara E, Maltese PE, Michelini S, Chiurazzi P, Paolacci S, Ceccarini MR, Beccari T, Bertelli M.
PMID: 34890031
Eur Rev Med Pharmacol Sci. 2021 Dec;25(1):23-32. doi: 10.26355/eurrev_202112_27330.

Adipocytes express various enzymes, such as aldo-keto reductases (AKR1C), 11β-hydroxysteroid dehydrogenase (11β-HSD), aromatase, 5α-reductases, 3β-HSD, and 17β-HSDs involved in steroid hormone metabolism in adipose tissues. Increased activity of AKR1C enzymes and their expression in mature adipocytes might indicate the...

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Kiani AK, Mor M, Bernini A, et al. Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes. Eur Rev Med Pharmacol Sci. 2021;25(1):23-32doi: 10.26355/eurrev_202112_27330.
Kiani, A. K., Mor, M., Bernini, A., Fulcheri, E., Michelini, S., Herbst, K. L., Buffelli, F., Belgrado, J. P., Kaftalli, J., Stuppia, L., Dautaj, A., Dhuli, K., Guda, T., Manara, E., Maltese, P. E., Michelini, S., Chiurazzi, P., Paolacci, S., Ceccarini, M. R., Beccari, T., & Bertelli, M. (2021). Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes. European review for medical and pharmacological sciences, 25(1), 23-32. https://doi.org/10.26355/eurrev_202112_27330
Kiani, A K, et al. "Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes." European review for medical and pharmacological sciences vol. 25,1 (2021): 23-32. doi: https://doi.org/10.26355/eurrev_202112_27330
Kiani AK, Mor M, Bernini A, Fulcheri E, Michelini S, Herbst KL, Buffelli F, Belgrado JP, Kaftalli J, Stuppia L, Dautaj A, Dhuli K, Guda T, Manara E, Maltese PE, Michelini S, Chiurazzi P, Paolacci S, Ceccarini MR, Beccari T, Bertelli M. Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes. Eur Rev Med Pharmacol Sci. 2021 Dec;25(1):23-32. doi: 10.26355/eurrev_202112_27330. PMID: 34890031.
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Comprehensive sex steroid profiling in multiple tissues reveals novel insights in sex steroid distribution in male mice.

Endocrinology

Colldén H, Nilsson ME, Norlén AK, Landin A, Windahl SH, Wu J, Gustafsson KL, Poutanen M, Ryberg H, Vandenput L, Ohlsson C.
PMID: 34999782
Endocrinology. 2022 Jan 06; doi: 10.1210/endocr/bqac001. Epub 2022 Jan 06.

A comprehensive atlas of sex steroid distribution in multiple tissues is currently lacking and how circulating and tissue sex steroid levels correlate remains unknown. Here, we adapted and validated a gas chromatography-tandem mass spectrometry method for simultaneous measurement of...

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Colldén H, Nilsson ME, Norlén AK, et al. Comprehensive sex steroid profiling in multiple tissues reveals novel insights in sex steroid distribution in male mice. Endocrinology. 2022;doi: 10.1210/endocr/bqac001.
Colldén, H., Nilsson, M. E., Norlén, A. K., Landin, A., Windahl, S. H., Wu, J., Gustafsson, K. L., Poutanen, M., Ryberg, H., Vandenput, L., & Ohlsson, C. (2022). Comprehensive sex steroid profiling in multiple tissues reveals novel insights in sex steroid distribution in male mice. Endocrinology, . https://doi.org/10.1210/endocr/bqac001
Colldén, Hannah, et al. "Comprehensive sex steroid profiling in multiple tissues reveals novel insights in sex steroid distribution in male mice." Endocrinology vol. (2022). doi: https://doi.org/10.1210/endocr/bqac001
Colldén H, Nilsson ME, Norlén AK, Landin A, Windahl SH, Wu J, Gustafsson KL, Poutanen M, Ryberg H, Vandenput L, Ohlsson C. Comprehensive sex steroid profiling in multiple tissues reveals novel insights in sex steroid distribution in male mice. Endocrinology. 2022 Jan 06; doi: 10.1210/endocr/bqac001. Epub 2022 Jan 06. PMID: 34999782.
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A Prospective Study of the Relationship Between Clinical Outcomes After Enzalutamide and Serum Androgen Levels Measured via Liquid Chromatography-tandem Mass Spectrometry in Patients with Castration-resistant Prostate Cancer.

European urology open science

Miyazawa Y, Sekine Y, Arai S, Nakamura T, Takezawa Y, Shimizu N, Matsuo Y, Ogura H, Takei T, Suzuki K.
PMID: 34337535
Eur Urol Open Sci. 2021 Jun 07;29:59-67. doi: 10.1016/j.euros.2021.05.003. eCollection 2021 Jul.

BACKGROUND: Enzalutamide (ENZ) is used to treat patients with castration-resistant prostate cancer (CRPC). However, the kinetics of serum androgens before and after ENZ treatment are unknown.OBJECTIVE: To elucidate the kinetics of serum androgens and explore the possibility of identifying...

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Miyazawa Y, Sekine Y, Arai S, et al. A Prospective Study of the Relationship Between Clinical Outcomes After Enzalutamide and Serum Androgen Levels Measured via Liquid Chromatography-tandem Mass Spectrometry in Patients with Castration-resistant Prostate Cancer. Eur Urol Open Sci. 2021;29:59-67doi: 10.1016/j.euros.2021.05.003.
Miyazawa, Y., Sekine, Y., Arai, S., Nakamura, T., Takezawa, Y., Shimizu, N., Matsuo, Y., Ogura, H., Takei, T., & Suzuki, K. (2021). A Prospective Study of the Relationship Between Clinical Outcomes After Enzalutamide and Serum Androgen Levels Measured via Liquid Chromatography-tandem Mass Spectrometry in Patients with Castration-resistant Prostate Cancer. European urology open science, 2959-67. https://doi.org/10.1016/j.euros.2021.05.003
Miyazawa, Yoshiyuki, et al. "A Prospective Study of the Relationship Between Clinical Outcomes After Enzalutamide and Serum Androgen Levels Measured via Liquid Chromatography-tandem Mass Spectrometry in Patients with Castration-resistant Prostate Cancer." European urology open science vol. 29 (2021): 59-67. doi: https://doi.org/10.1016/j.euros.2021.05.003
Miyazawa Y, Sekine Y, Arai S, Nakamura T, Takezawa Y, Shimizu N, Matsuo Y, Ogura H, Takei T, Suzuki K. A Prospective Study of the Relationship Between Clinical Outcomes After Enzalutamide and Serum Androgen Levels Measured via Liquid Chromatography-tandem Mass Spectrometry in Patients with Castration-resistant Prostate Cancer. Eur Urol Open Sci. 2021 Jun 07;29:59-67. doi: 10.1016/j.euros.2021.05.003. eCollection 2021 Jul. PMID: 34337535; PMCID: PMC8317787.
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Production of 11-Oxygenated Androgens by Testicular Adrenal Rest Tumors.

The Journal of clinical endocrinology and metabolism

Schröder MAM, Turcu AF, O'Day P, van Herwaarden AE, Span PN, Auchus RJ, Sweep FCGJ, Claahsen-van der Grinten HL.
PMID: 34390337
J Clin Endocrinol Metab. 2022 Jan 01;107(1):e272-e280. doi: 10.1210/clinem/dgab598.

CONTEXT: Testicular adrenal rest tumors (TART) are a common complication in males with classic 21-hydroxylase deficiency (21OHD). TART are likely to contribute to the androgen excess in 21OHD patients, but a direct quantification of steroidogenesis from these tumors has...

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Schröder MAM, Turcu AF, O'Day P, et al. Production of 11-Oxygenated Androgens by Testicular Adrenal Rest Tumors. J Clin Endocrinol Metab. 2022;107(1):e272-e280doi: 10.1210/clinem/dgab598.
Schröder, M. A. M., Turcu, A. F., O'Day, P., van Herwaarden, A. E., Span, P. N., Auchus, R. J., Sweep, F. C. G. J., & Claahsen-van der Grinten, H. L. (2022). Production of 11-Oxygenated Androgens by Testicular Adrenal Rest Tumors. The Journal of clinical endocrinology and metabolism, 107(1), e272-e280. https://doi.org/10.1210/clinem/dgab598
Schröder, Mariska A M, et al. "Production of 11-Oxygenated Androgens by Testicular Adrenal Rest Tumors." The Journal of clinical endocrinology and metabolism vol. 107,1 (2022): e272-e280. doi: https://doi.org/10.1210/clinem/dgab598
Schröder MAM, Turcu AF, O'Day P, van Herwaarden AE, Span PN, Auchus RJ, Sweep FCGJ, Claahsen-van der Grinten HL. Production of 11-Oxygenated Androgens by Testicular Adrenal Rest Tumors. J Clin Endocrinol Metab. 2022 Jan 01;107(1):e272-e280. doi: 10.1210/clinem/dgab598. PMID: 34390337.
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Showing 1693 to 1704 of 1720 entries