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Showing 13 to 24 of 845 entries
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Catechin and epicatechin reduce mitochondrial dysfunction and oxidative stress induced by amiodarone in human lung fibroblasts.

Journal of arrhythmia

Silva Santos LF, Stolfo A, Calloni C, Salvador M.
PMID: 28607618
J Arrhythm. 2017 Jun;33(3):220-225. doi: 10.1016/j.joa.2016.09.004. Epub 2016 Oct 22.

BACKGROUND: Amiodarone (AMD) and its metabolite N-desethylamiodarone can cause some adverse effects, which include pulmonary toxicity. Some studies suggest that mitochondrial dysfunction and oxidative stress may play a role in these adverse effects. Catechin and epicatechin are recognized as...

Effect of stem cell therapy on amiodarone induced fibrosing interstitial lung disease in albino rat.

International journal of stem cells

Zaglool SS, Zickri MB, Abd El Aziz DH, Mabrouk D, Metwally HG.
PMID: 24298346
Int J Stem Cells. 2011 Nov;4(2):133-42. doi: 10.15283/ijsc.2011.4.2.133.

BACKGROUND AND OBJECTIVES: The fibrosing forms of interstitial lung disease (ILD) are associated with significant morbidity and mortality. ILD may be idiopathic, secondary to occupational, infection, complicate rheumatic diseases or drug induced. Efficacy of antifibrotic agents is as far...

Pre-injury beta blocker use does not affect the hyperdynamic response in older trauma patients.

Journal of emergencies, trauma, and shock

Evans DC, Khoo KM, Radulescu A, Cook CH, Gerlach AT, Papadimos TJ, Steinberg SM, Stawicki SP, Eiferman DS.
PMID: 25400393
J Emerg Trauma Shock. 2014 Oct;7(4):305-9. doi: 10.4103/0974-2700.142766.

PURPOSE: Trauma dogma dictates that the physiologic response to injury is blunted by beta-blockers and other cardiac medications. We sought to determine how the pre-injury cardiac medication profile influences admission physiology and post-injury outcomes.MATERIALS AND METHODS: Trauma patients older...

Prevalence of amiodarone-induced thyrotoxicosis and associated risk factors in Japanese patients.

International journal of endocrinology

Uchida T, Kasai T, Takagi A, Sekita G, Komiya K, Takeno K, Shigihara N, Shimada K, Miyauchi K, Fujitani Y, Daida H, Watada H.
PMID: 25053942
Int J Endocrinol. 2014;2014:534904. doi: 10.1155/2014/534904. Epub 2014 Jun 25.

Amiodarone is a widely used agent for life-threatening arrhythmias. Although amiodarone-induced thyrotoxicosis (AIT) is a major adverse effect that can cause recurrence of arrhythmias and exacerbation of heart failure, risk factors for AIT among amiodarone-treated Japanese patients have not...

Drugs in breastfeeding.

Australian prescriber

Hotham N, Hotham E.
PMID: 26648652
Aust Prescr. 2015 Oct;38(5):156-9. doi: 10.18773/austprescr.2015.056. Epub 2015 Oct 01.

Most commonly used drugs are relatively safe for breastfed babies. The dose received via milk is generally small and much less than the known safe doses of the same drug given directly to neonates and infants. Drugs contraindicated during...

Characteristics of corneal phospholipidosis induced by topical ocular application of chloroquine and amiodarone in rabbits.

Journal of toxicologic pathology

Yamagiwa Y, Haranosono Y, Nemoto S, Atsumi I, Kurata M, Kito G, Hatakeyama H, Koizumi H, Sakaki H.
PMID: 28458451
J Toxicol Pathol. 2017 Apr;30(2):135-143. doi: 10.1293/tox.2016-0003. Epub 2016 Nov 27.

Several cationic-amphiphilic drugs such as chloroquine and amiodarone are known to induce phospholipidosis in the cornea by systemic administration. However, the characteristics of ophthalmological and pathological changes when phospholipidosis-inducing drugs are topically applied have not been well studied. This...

The blue child - amiodarone-induced blue-gray skin syndrome and pulmonary mass in a child.

Clinical case reports

Paech C, Wagner F, Suchowerskyj P, Weidenbach M.
PMID: 27014451
Clin Case Rep. 2016 Feb 08;4(3):276-8. doi: 10.1002/ccr3.483. eCollection 2016 Mar.

Adverse effects of amiodarone are rarely seen in pediatric patients, but may occur if amiodarone is applied for long-term treatment. Two rather rare phenomena are blue-gray skin pigmentation and pulmonary mass. They represent important differential diagnoses from more common...

The effect of long-term amiodarone administration on myocardial fibrosis and evolution of left ventricular remodeling in a porcine model of ischemic cardiomyopathy.

SpringerPlus

Zagorianou A, Marougkas M, Drakos SG, Diakos N, Konstantopoulos P, Perrea DN, Anastasiou-Nana M, Malliaras K.
PMID: 27652141
Springerplus. 2016 Sep 15;5(1):1568. doi: 10.1186/s40064-016-3249-3. eCollection 2016.

Amiodarone is effective in suppressing arrhythmias in heart failure patients. We investigated the effect of long-term amiodarone administration on myocardial fibrosis and left ventricular (LV) remodeling in a porcine model of ischemic cardiomyopathy. Eighteen infarcted farm pigs were randomized...

Factors affecting the quality of anticoagulation with warfarin: experience of one cardiac centre.

Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

Ciurus T, Cichocka-Radwan A, Lelonek M.
PMID: 26855650
Kardiochir Torakochirurgia Pol. 2015 Dec;12(4):334-40. doi: 10.5114/kitp.2015.56784. Epub 2015 Dec 30.

INTRODUCTION: The risk of complications in anticoagulation therapy can be reduced by maximising the percentage of time spent by the patient in the optimal therapeutic range (TTR). However, little is known about the predictors of anticoagulation control. The aim...

Intraoperative loading dose of amiodarone for prophylaxis against atrial fibrillation after valvular heart surgery.

Anesthesia, essays and researches

Amr YM, Elmistekawy EM, Hammad AA.
PMID: 25885238
Anesth Essays Res. 2010 Jul-Dec;4(2):96-101. doi: 10.4103/0259-1162.73515.

OBJECTIVE: Benefit of amiodarone in restoring sinus rhythm (SR) after cardiac surgery was concluded in previous studies that used different protocols for giving amiodarone. The purpose of this study was to assess the use of single parenteral intraoperative loading...

Narrow Complex Ventricular Tachycardia.

Cureus

Sundhu M, Yildiz M, Gul S, Syed M, Azher I, Mosteller R.
PMID: 28875096
Cureus. 2017 Jul 04;9(7):e1423. doi: 10.7759/cureus.1423.

Myocardial infarctions are frequently complicated by tachyarrhythmias, which commonly have wide QRS complexes (QRS duration > 120 milliseconds). Many published criteria exist to help differentiate between ventricular and supraventricular mechanisms. We present a case of a 61-year-old male with...

Atrial Fibrillation in Acute Coronary Syndrome.

Journal of atrial fibrillation

Rubenstein JC, Cinquegrani MP, Wright J.
PMID: 28496750
J Atr Fibrillation. 2012 Jun 15;5(1):551. doi: 10.4022/jafib.551. eCollection 2012.

Atrial fibrillation (AF) is a common cardiac arrhythmia occurring in an estimated 2.7 to 6.1 million people in the United States. The risk factors for the development of AF are very similar to those for developing coronary artery disease,...

Showing 13 to 24 of 845 entries