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Metal-Free Activation of a C(sp)-H Bond of Aryl Acetylenes.

Chemistry (Weinheim an der Bergstrasse, Germany)

Rout L, Parida BB, Florent JC, Johannes L, Choudhury SK, Phaomei G, Scanlon J, Bertounesque E.
PMID: 27504988
Chemistry. 2016 Oct 10;22(42):14812-14815. doi: 10.1002/chem.201603003. Epub 2016 Aug 30.

C(sp)-H Bond activation of acetylene molecule still remains a challenge for synthetic organic chemists. In practice, acetylenes are activated by strong bases and metals. The first example for activating acetylenic protons under base and metal-free conditions is reported here....

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Rout L, Parida BB, Florent JC, et al. Metal-Free Activation of a C(sp)-H Bond of Aryl Acetylenes. Chemistry. 2016;22(42):14812-14815doi: 10.1002/chem.201603003.
Rout, L., Parida, B. B., Florent, J. C., Johannes, L., Choudhury, S. K., Phaomei, G., Scanlon, J., & Bertounesque, E. (2016). Metal-Free Activation of a C(sp)-H Bond of Aryl Acetylenes. Chemistry (Weinheim an der Bergstrasse, Germany), 22(42), 14812-14815. https://doi.org/10.1002/chem.201603003
Rout, Laxmidhar, et al. "Metal-Free Activation of a C(sp)-H Bond of Aryl Acetylenes." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 22,42 (2016): 14812-14815. doi: https://doi.org/10.1002/chem.201603003
Rout L, Parida BB, Florent JC, Johannes L, Choudhury SK, Phaomei G, Scanlon J, Bertounesque E. Metal-Free Activation of a C(sp)-H Bond of Aryl Acetylenes. Chemistry. 2016 Oct 10;22(42):14812-14815. doi: 10.1002/chem.201603003. Epub 2016 Aug 30. PMID: 27504988.
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The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba.

Evidence-based complementary and alternative medicine : eCAM

Zhang X, Wang Y, Liang Q, Ma Z, Xiao C, Tan H, Gao Y.
PMID: 25024734
Evid Based Complement Alternat Med. 2014;2014:892797. doi: 10.1155/2014/892797. Epub 2014 Jun 12.

The eighteen incompatible medicaments is an important theory in traditional Chinese medicine. The theory suggests that drugs in the eighteen incompatible medicaments can be toxic when used together. Veratrum nigrum L. and Radix paeoniae alba belong to the eighteen...

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Zhang X, Wang Y, Liang Q, et al. The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba. Evid Based Complement Alternat Med. 2014;2014:892797doi: 10.1155/2014/892797.
Zhang, X., Wang, Y., Liang, Q., Ma, Z., Xiao, C., Tan, H., & Gao, Y. (2014). The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba. Evidence-based complementary and alternative medicine : eCAM, 2014892797. https://doi.org/10.1155/2014/892797
Zhang, Xianxie, et al. "The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba." Evidence-based complementary and alternative medicine : eCAM vol. 2014 (2014): 892797. doi: https://doi.org/10.1155/2014/892797
Zhang X, Wang Y, Liang Q, Ma Z, Xiao C, Tan H, Gao Y. The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba. Evid Based Complement Alternat Med. 2014;2014:892797. doi: 10.1155/2014/892797. Epub 2014 Jun 12. PMID: 25024734; PMCID: PMC4082919.
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Endophytic Fungi Isolated from Coleus amboinicus Lour Exhibited Antimicrobial Activity.

Advanced pharmaceutical bulletin

Astuti P, Sudarsono S, Nisak K, Nugroho GW.
PMID: 25671195
Adv Pharm Bull. 2014 Dec;4:599-605. doi: 10.5681/apb.2014.088. Epub 2014 Dec 31.

PURPOSE: Coleus amboinicus is a medicinal plant traditionally used to treat various diseases such as throat infection, cough and fever, diarrhea, nasal congestion and digestive problems. The plant was explored for endophytic fungi producing antimicrobial agents.METHODS: Screening for endophytic...

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Astuti P, Sudarsono S, Nisak K, et al. Endophytic Fungi Isolated from Coleus amboinicus Lour Exhibited Antimicrobial Activity. Adv Pharm Bull. 2014;4:599-605doi: 10.5681/apb.2014.088.
Astuti, P., Sudarsono, S., Nisak, K., & Nugroho, G. W. (2014). Endophytic Fungi Isolated from Coleus amboinicus Lour Exhibited Antimicrobial Activity. Advanced pharmaceutical bulletin, 4599-605. https://doi.org/10.5681/apb.2014.088
Astuti, Puji, et al. "Endophytic Fungi Isolated from Coleus amboinicus Lour Exhibited Antimicrobial Activity." Advanced pharmaceutical bulletin vol. 4 (2014): 599-605. doi: https://doi.org/10.5681/apb.2014.088
Astuti P, Sudarsono S, Nisak K, Nugroho GW. Endophytic Fungi Isolated from Coleus amboinicus Lour Exhibited Antimicrobial Activity. Adv Pharm Bull. 2014 Dec;4:599-605. doi: 10.5681/apb.2014.088. Epub 2014 Dec 31. PMID: 25671195; PMCID: PMC4312411.
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Enantioselective Construction of the ABCDE Pentacyclic Core of the Strychnos Alkaloids.

Organic letters

Gammack Yamagata AD, Dixon DJ.
PMID: 28357866
Org Lett. 2017 Apr 07;19(7):1894-1897. doi: 10.1021/acs.orglett.7b00669. Epub 2017 Mar 30.

An efficient enantioselective 12-step synthesis of the ABCDE pentacyclic core of the Strychnos alkaloids is described. A key feature of this approach is an organocatalyzed enantioselective desymmetrization to generate the morphan core in high ee and dr. After palladium-catalyzed...

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Gammack Yamagata AD, Dixon DJ. Enantioselective Construction of the ABCDE Pentacyclic Core of the Strychnos Alkaloids. Org Lett. 2017;19(7):1894-1897doi: 10.1021/acs.orglett.7b00669.
Gammack Yamagata, A. D., & Dixon, D. J. (2017). Enantioselective Construction of the ABCDE Pentacyclic Core of the Strychnos Alkaloids. Organic letters, 19(7), 1894-1897. https://doi.org/10.1021/acs.orglett.7b00669
Gammack Yamagata, Adam D, and Dixon, Darren J. "Enantioselective Construction of the ABCDE Pentacyclic Core of the Strychnos Alkaloids." Organic letters vol. 19,7 (2017): 1894-1897. doi: https://doi.org/10.1021/acs.orglett.7b00669
Gammack Yamagata AD, Dixon DJ. Enantioselective Construction of the ABCDE Pentacyclic Core of the Strychnos Alkaloids. Org Lett. 2017 Apr 07;19(7):1894-1897. doi: 10.1021/acs.orglett.7b00669. Epub 2017 Mar 30. PMID: 28357866.
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Evaluation of anthelmintic activity and in silico PASS assisted prediction of Cordia dichotoma (Forst.) root extract.

Ancient science of life

Jamkhande PG, Barde SR.
PMID: 25737609
Anc Sci Life. 2014 Jul-Sep;34(1):39-43. doi: 10.4103/0257-7941.150779.

BACKGROUND: Worm infection and associated complications are severe problems that afflict a large population worldwide. Failure of synthetic drugs in worm infections because of drug resistance has made alternative drug therapy desirable. Cordia dichotoma (Forst.) is an ethnomedicinal plant...

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Jamkhande PG, Barde SR. Evaluation of anthelmintic activity and in silico PASS assisted prediction of Cordia dichotoma (Forst.) root extract. Anc Sci Life. 2014;34(1):39-43doi: 10.4103/0257-7941.150779.
Jamkhande, P. G., & Barde, S. R. (2014). Evaluation of anthelmintic activity and in silico PASS assisted prediction of Cordia dichotoma (Forst.) root extract. Ancient science of life, 34(1), 39-43. https://doi.org/10.4103/0257-7941.150779
Jamkhande, Prasad G, and Barde, Sonal R. "Evaluation of anthelmintic activity and in silico PASS assisted prediction of Cordia dichotoma (Forst.) root extract." Ancient science of life vol. 34,1 (2014): 39-43. doi: https://doi.org/10.4103/0257-7941.150779
Jamkhande PG, Barde SR. Evaluation of anthelmintic activity and in silico PASS assisted prediction of Cordia dichotoma (Forst.) root extract. Anc Sci Life. 2014 Jul-Sep;34(1):39-43. doi: 10.4103/0257-7941.150779. PMID: 25737609; PMCID: PMC4342648.
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The Potential of β Carbolin Alkaloids to Hinder Growth and Reverse Chloroquine Resistance in Plasmodium falciparum.

Iranian journal of parasitology

Ibraheem ZO, Abdul Majid R, Mohd Noor S, Mohd Sidek H, Basir R.
PMID: 26811724
Iran J Parasitol. 2015 Oct-Dec;10(4):577-83.

BACKGROUND: Nowadays, scourge of malaria as a fatalistic disease has increased due to emergence of drug resistance and tolerance among different strains of Plasmodium falciparum. Emergence of chloroquine (CQ) resistance has worsened the calamity as CQ is still considered...

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Ibraheem ZO, Abdul Majid R, Mohd Noor S, et al. The Potential of β Carbolin Alkaloids to Hinder Growth and Reverse Chloroquine Resistance in Plasmodium falciparum. Iran J Parasitol. 2015;10(4):577-83
Ibraheem, Z. O., Abdul Majid, R., Mohd Noor, S., Mohd Sidek, H., & Basir, R. (2015). The Potential of β Carbolin Alkaloids to Hinder Growth and Reverse Chloroquine Resistance in Plasmodium falciparum. Iranian journal of parasitology, 10(4), 577-83.
Ibraheem, Zaid O, et al. "The Potential of β Carbolin Alkaloids to Hinder Growth and Reverse Chloroquine Resistance in Plasmodium falciparum." Iranian journal of parasitology vol. 10,4 (2015): 577-83.
Ibraheem ZO, Abdul Majid R, Mohd Noor S, Mohd Sidek H, Basir R. The Potential of β Carbolin Alkaloids to Hinder Growth and Reverse Chloroquine Resistance in Plasmodium falciparum. Iran J Parasitol. 2015 Oct-Dec;10(4):577-83. PMID: 26811724; PMCID: PMC4724834.
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Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death .

Oncology letters

Bryukhovetskiy I, Lyakhova I, Mischenko P, Milkina E, Zaitsev S, Khotimchenko Y, Bryukhovetskiy A, Polevshchikov A, Kudryavtsev I, Khotimchenko M, Zhidkov M.
PMID: 28356953
Oncol Lett. 2017 Feb;13(2):738-746. doi: 10.3892/ol.2016.5478. Epub 2016 Dec 09.

Glioblastoma multiforme is an invasive malignant glial brain tumor with a poor prognosis for patients. The primary reasons that lead to the development of treatment resistance are associated with tumor cells infiltrating the brain parenchyma and the specific properties...

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Bryukhovetskiy I, Lyakhova I, Mischenko P, et al. Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death . Oncol Lett. 2016;13(2):738-746doi: 10.3892/ol.2016.5478.
Bryukhovetskiy, I., Lyakhova, I., Mischenko, P., Milkina, E., Zaitsev, S., Khotimchenko, Y., Bryukhovetskiy, A., Polevshchikov, A., Kudryavtsev, I., Khotimchenko, M., & Zhidkov, M. (2017). Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death . Oncology letters, 13(2), 738-746. https://doi.org/10.3892/ol.2016.5478
Bryukhovetskiy, Igor, et al. "Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death ." Oncology letters vol. 13,2 (2017): 738-746. doi: https://doi.org/10.3892/ol.2016.5478
Bryukhovetskiy I, Lyakhova I, Mischenko P, Milkina E, Zaitsev S, Khotimchenko Y, Bryukhovetskiy A, Polevshchikov A, Kudryavtsev I, Khotimchenko M, Zhidkov M. Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death . Oncol Lett. 2017 Feb;13(2):738-746. doi: 10.3892/ol.2016.5478. Epub 2016 Dec 09. PMID: 28356953; PMCID: PMC5351310.
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Application of a strategy based on metabolomics guided promoting blood circulation bioactivity compounds screening of vinegar.

Chemistry Central journal

Ning Z, Liu Z, Song Z, Wang C, Liu Y, Gan J, Ma X, Lu A.
PMID: 29086814
Chem Cent J. 2017 May 08;11(1):38. doi: 10.1186/s13065-017-0265-5.

BACKGROUND: Rice vinegar (RV) and white vinegar (WV) as daily flavoring, have also used as accessory in traditional Chinese medicine processing. As we know, the promoting blood circulation efficiency could be enhanced when herbs processed by vinegar. Number of...

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Ning Z, Liu Z, Song Z, et al. Application of a strategy based on metabolomics guided promoting blood circulation bioactivity compounds screening of vinegar. Chem Cent J. 2017;11(1):38doi: 10.1186/s13065-017-0265-5.
Ning, Z., Liu, Z., Song, Z., Wang, C., Liu, Y., Gan, J., Ma, X., & Lu, A. (2017). Application of a strategy based on metabolomics guided promoting blood circulation bioactivity compounds screening of vinegar. Chemistry Central journal, 11(1), 38. https://doi.org/10.1186/s13065-017-0265-5
Ning, Zhangchi, et al. "Application of a strategy based on metabolomics guided promoting blood circulation bioactivity compounds screening of vinegar." Chemistry Central journal vol. 11,1 (2017): 38. doi: https://doi.org/10.1186/s13065-017-0265-5
Ning Z, Liu Z, Song Z, Wang C, Liu Y, Gan J, Ma X, Lu A. Application of a strategy based on metabolomics guided promoting blood circulation bioactivity compounds screening of vinegar. Chem Cent J. 2017 May 08;11(1):38. doi: 10.1186/s13065-017-0265-5. PMID: 29086814; PMCID: PMC5422338.
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Basic opioid pharmacology: an update.

British journal of pain

Pathan H, Williams J.
PMID: 26516461
Br J Pain. 2012 Feb;6(1):11-6. doi: 10.1177/2049463712438493.

Opioids are a group of analgesic agents commonly used in clinical practice. There are three classical opioid receptors (DOP, KOP and MOP), while the novel NOP receptor is considered to be a non-opioid branch of the opioid receptor family....

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Pathan H, Williams J. Basic opioid pharmacology: an update. Br J Pain. 2012;6(1):11-6doi: 10.1177/2049463712438493.
Pathan, H., & Williams, J. (2012). Basic opioid pharmacology: an update. British journal of pain, 6(1), 11-6. https://doi.org/10.1177/2049463712438493
Pathan, Hasan, and Williams, John. "Basic opioid pharmacology: an update." British journal of pain vol. 6,1 (2012): 11-6. doi: https://doi.org/10.1177/2049463712438493
Pathan H, Williams J. Basic opioid pharmacology: an update. Br J Pain. 2012 Feb;6(1):11-6. doi: 10.1177/2049463712438493. PMID: 26516461; PMCID: PMC4590096.
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CrBPF1 overexpression alters transcript levels of terpenoid indole alkaloid biosynthetic and regulatory genes.

Frontiers in plant science

Li CY, Leopold AL, Sander GW, Shanks JV, Zhao L, Gibson SI.
PMID: 26483828
Front Plant Sci. 2015 Oct 01;6:818. doi: 10.3389/fpls.2015.00818. eCollection 2015.

Terpenoid indole alkaloid (TIA) biosynthesis in Catharanthus roseus is a complex and highly regulated process. Understanding the biochemistry and regulation of the TIA pathway is of particular interest as it may allow the engineering of plants to accumulate higher...

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Li CY, Leopold AL, Sander GW, et al. CrBPF1 overexpression alters transcript levels of terpenoid indole alkaloid biosynthetic and regulatory genes. Front Plant Sci. 2015;6:818doi: 10.3389/fpls.2015.00818.
Li, C. Y., Leopold, A. L., Sander, G. W., Shanks, J. V., Zhao, L., & Gibson, S. I. (2015). CrBPF1 overexpression alters transcript levels of terpenoid indole alkaloid biosynthetic and regulatory genes. Frontiers in plant science, 6818. https://doi.org/10.3389/fpls.2015.00818
Li, Chun Yao, et al. "CrBPF1 overexpression alters transcript levels of terpenoid indole alkaloid biosynthetic and regulatory genes." Frontiers in plant science vol. 6 (2015): 818. doi: https://doi.org/10.3389/fpls.2015.00818
Li CY, Leopold AL, Sander GW, Shanks JV, Zhao L, Gibson SI. CrBPF1 overexpression alters transcript levels of terpenoid indole alkaloid biosynthetic and regulatory genes. Front Plant Sci. 2015 Oct 01;6:818. doi: 10.3389/fpls.2015.00818. eCollection 2015. PMID: 26483828; PMCID: PMC4589645.
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BIOCHEMICAL PHENOTYPIC AND GENETIC STUDIES OF TWO INTRODUCED FIRE ANTS AND THEIR HYBRID (HYMENOPTERA: FORMICIDAE).

Evolution; international journal of organic evolution

Ross KG, Meer RKV, Fletcher DJC, Vargo EL.
PMID: 28568766
Evolution. 1987 Mar;41(2):280-293. doi: 10.1111/j.1558-5646.1987.tb05797.x.

Two introduced fire ants, Solenopsis invicta and S. richteri, and their hybrid were studied using phenotypic markers from gas chromatographic analysis of hydrocarbons and venom alkaloids, as well as genetic markers from enzyme electrophoresis. Both methods show that extensive...

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Ross KG, Meer RKV, Fletcher DJC, et al. BIOCHEMICAL PHENOTYPIC AND GENETIC STUDIES OF TWO INTRODUCED FIRE ANTS AND THEIR HYBRID (HYMENOPTERA: FORMICIDAE). Evolution. 1987;41(2):280-293doi: 10.1111/j.1558-5646.1987.tb05797.x.
Ross, K. G., Meer, R. K. V., Fletcher, D. J. C., & Vargo, E. L. (1987). BIOCHEMICAL PHENOTYPIC AND GENETIC STUDIES OF TWO INTRODUCED FIRE ANTS AND THEIR HYBRID (HYMENOPTERA: FORMICIDAE). Evolution; international journal of organic evolution, 41(2), 280-293. https://doi.org/10.1111/j.1558-5646.1987.tb05797.x
Ross, Kenneth G, et al. "BIOCHEMICAL PHENOTYPIC AND GENETIC STUDIES OF TWO INTRODUCED FIRE ANTS AND THEIR HYBRID (HYMENOPTERA: FORMICIDAE)." Evolution; international journal of organic evolution vol. 41,2 (1987): 280-293. doi: https://doi.org/10.1111/j.1558-5646.1987.tb05797.x
Ross KG, Meer RKV, Fletcher DJC, Vargo EL. BIOCHEMICAL PHENOTYPIC AND GENETIC STUDIES OF TWO INTRODUCED FIRE ANTS AND THEIR HYBRID (HYMENOPTERA: FORMICIDAE). Evolution. 1987 Mar;41(2):280-293. doi: 10.1111/j.1558-5646.1987.tb05797.x. PMID: 28568766.
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Studies on the Red Sea Sponge Haliclona sp. for its Chemical and Cytotoxic Properties.

Pharmacognosy magazine

Al-Massarani SM, El-Gamal AA, Al-Said MS, Abdel-Kader MS, Ashour AE, Kumar A, Abdel-Mageed WM, Al-Rehaily AJ, Ghabbour HA, Fun HK.
PMID: 27076747
Pharmacogn Mag. 2016 Apr-Jun;12(46):114-9. doi: 10.4103/0973-1296.177906.

BACKGROUND: A great number of novel compounds with rich chemical diversity and significant bioactivity have been reported from Red Sea sponges.OBJECTIVE: To isolate, identify, and evaluate the cytotoxic activity of the chemical constituents of a sponge belonging to genus...

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Al-Massarani SM, El-Gamal AA, Al-Said MS, et al. Studies on the Red Sea Sponge Haliclona sp. for its Chemical and Cytotoxic Properties. Pharmacogn Mag. 2016;12(46):114-9doi: 10.4103/0973-1296.177906.
Al-Massarani, S. M., El-Gamal, A. A., Al-Said, M. S., Abdel-Kader, M. S., Ashour, A. E., Kumar, A., Abdel-Mageed, W. M., Al-Rehaily, A. J., Ghabbour, H. A., & Fun, H. K. (2016). Studies on the Red Sea Sponge Haliclona sp. for its Chemical and Cytotoxic Properties. Pharmacognosy magazine, 12(46), 114-9. https://doi.org/10.4103/0973-1296.177906
Al-Massarani, Shaza Mohamed, et al. "Studies on the Red Sea Sponge Haliclona sp. for its Chemical and Cytotoxic Properties." Pharmacognosy magazine vol. 12,46 (2016): 114-9. doi: https://doi.org/10.4103/0973-1296.177906
Al-Massarani SM, El-Gamal AA, Al-Said MS, Abdel-Kader MS, Ashour AE, Kumar A, Abdel-Mageed WM, Al-Rehaily AJ, Ghabbour HA, Fun HK. Studies on the Red Sea Sponge Haliclona sp. for its Chemical and Cytotoxic Properties. Pharmacogn Mag. 2016 Apr-Jun;12(46):114-9. doi: 10.4103/0973-1296.177906. PMID: 27076747; PMCID: PMC4809165.
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Showing 25 to 36 of 4320 entries