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Showing 13 to 24 of 4320 entries
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Inhibitors of pancreatic lipase: state of the art and clinical perspectives.

EXCLI journal

Lunagariya NA, Patel NK, Jagtap SC, Bhutani KK.
PMID: 26417311
EXCLI J. 2014 Aug 22;13:897-921. eCollection 2014.

Obesity is a disorder of lipid metabolism and continues to be a global problem, ranking fifth for deaths worldwide. It also leads to diabetes, cardiovascular disorders, musculoskeletal disorders and some types of cancer. Obesity is regarded as the output...

In Vitro Anticancer Activity of a Nonpolar Fraction from Gynostemma pentaphyllum (Thunb.) Makino.

Evidence-based complementary and alternative medicine : eCAM

Li Y, Huang J, Lin W, Yuan Z, Feng S, Xie Y, Ma W.
PMID: 27034692
Evid Based Complement Alternat Med. 2016;2016:6308649. doi: 10.1155/2016/6308649. Epub 2016 Feb 29.

Gynostemma pentaphyllum (Thunb.) Makino (GpM) has been widely used in traditional Chinese medicine (TCM) for the treatment of various diseases including cancer. Most previous studies have focused primarily on polar fractions of GpM for anticancer activities. In this study,...

Response to Heethoff, Norton, and Raspotnig: Ant and Mite Diversity Drives Toxin Variation in the Little Devil Poison Frog and Erratum.

Journal of chemical ecology

McGugan JR, Byrd GD, Roland AB, Caty SN, Kabir N, Tapia EE, Trauger SA, Coloma LA, O'Connell LA.
PMID: 27672058
J Chem Ecol. 2016 Aug;42(8):845-848. doi: 10.1007/s10886-016-0759-y.

Our recent publication titled "Ant and Mite Diversity Drives Toxin Variation in the Little Devil Poison Frog" aimed to describe how variation in diet contributes to population differences in toxin profiles of poison frogs. Some poison frogs (Family Dendrobatidae)...

Biophysical aspects and biological implications of the interaction of benzophenanthridine alkaloids with DNA.

Biophysical reviews

Maiti M, Kumar GS.
PMID: 28509993
Biophys Rev. 2009 Sep;1(3):119-129. doi: 10.1007/s12551-009-0014-7. Epub 2009 Aug 25.

Benzophenanthridine alkaloids represent a very interesting and significant group of natural products that exhibit a broad range of biological and pharmacological properties. Among this group of alkaloids, sanguinarine, nitidine, fagaronine, and chelerythrine have the potential to form molecular complexes...

Therapeutic efficacy of ethanolic extract of Aerva javanica aerial parts in the amelioration of CCl4-induced hepatotoxicity and oxidative damage in rats.

Food & nutrition research

Arbab AH, Parvez MK, Al-Dosari MS, Al-Rehaily AJ, Ibrahim KE, Alam P, Alsaid MS, Rafatullah S.
PMID: 27059702
Food Nutr Res. 2016 Apr 07;60:30864. doi: 10.3402/fnr.v60.30864. eCollection 2016.

BACKGROUND: Liver diseases, the fifth most common cause of global death, can be metabolic, toxin-induced, or infective. Though approximately 35 Saudi medicinal plants are traditionally used to treat liver disorders, the hepatoprotective potential of Aerva javanica has not been...

Diastereoselective Synthesis of and Mechanistic Understanding for the Formation of 2-Piperidinones from Imines and Cyano-Substituted Anhydrides.

Chemistry (Weinheim an der Bergstrasse, Germany)

Di Maso MJ, Snyder KM, De Souza Fernandes F, Pattawong O, Tan DQ, Fettinger JC, Cheong PH, Shaw JT.
PMID: 26929008
Chemistry. 2016 Mar 24;22(14):4794-801. doi: 10.1002/chem.201504424. Epub 2016 Mar 01.

2-Piperidinones are synthesized in a single step from imines and 2-cyano glutaric anhydrides. The reaction provides the products in good diastereoselectivity and generates a quaternary stereogenic center. Substitutions on the anhydride skeleton are well tolerated to provide 2-piperidinones with...

Contemporary Understanding of miRNA-Based Regulation of Secondary Metabolites Biosynthesis in Plants.

Frontiers in plant science

Gupta OP, Karkute SG, Banerjee S, Meena NL, Dahuja A.
PMID: 28424705
Front Plant Sci. 2017 Mar 29;8:374. doi: 10.3389/fpls.2017.00374. eCollection 2017.

Plant's secondary metabolites such as flavonoids, terpenoids, and alkaloids

A Historical View of Motion Sickness-A Plague at Sea and on Land, Also with Military Impact.

Frontiers in neurology

Huppert D, Benson J, Brandt T.
PMID: 28421029
Front Neurol. 2017 Apr 04;8:114. doi: 10.3389/fneur.2017.00114. eCollection 2017.

Seasickness and its triggers, symptoms, and preventive measures were well known in antiquity. This chapter is based on an analysis of descriptions of motion sickness, in particular seasickness, in ancient Greek, Roman, and Chinese literature. A systematic search was...

Mitigation of Ergot Vasoconstriction by Clover Isoflavones in Goats (Capra hircus).

Frontiers in veterinary science

Aiken GE, Flythe MD, Kagan IA, Ji H, Bush LP.
PMID: 26973844
Front Vet Sci. 2016 Mar 04;3:17. doi: 10.3389/fvets.2016.00017. eCollection 2016.

Ergot alkaloids produced by a fungal endophyte (Epichloƫ coenophiala; formerly Neotyphodium coenophialum) that infects tall fescue (Lolium arundinaceum) can induce persistent constriction of the vasculature in ruminants, hindering their capability to thermo-regulate core body temperature. There is evidence that...

Anti-plasmodial activity of ethanolic extract of root and stem back of Cassia sieberiana DC on mice.

Journal of intercultural ethnopharmacology

Abdulrazak N, Asiya UI, Usman NS, Unata IM, Farida A.
PMID: 26401393
J Intercult Ethnopharmacol. 2015 Apr-Jun;4(2):96-101. doi: 10.5455/jice.20141231014333. Epub 2015 Jan 20.

AIM: This study assessed within 4 days of suppressive test in vivo antimalarial activity of Ethanolic extract of root and stem bark of Cassia sieberiana DC against chloroquine sensitive strain of Plasmodium berghei NK65 in mice.METHODOLOGY: Two sets, each...

Death and Neurological Devastation From Intrathecal Vinca Alkaloids.

P & T : a peer-reviewed journal for formulary management

Grissinger M.
PMID: 27504060
P T. 2016 Aug;41(8):464-525.

Inadvertent intrathecal vincristine administration causes fatalities.

Metabolomics driven analysis of Erythrina lysistemon cell suspension culture in response to methyl jasmonate elicitation.

Journal of advanced research

Farag MA, Mekky H, El-Masry S.
PMID: 27504198
J Adv Res. 2016 Sep;7(5):681-9. doi: 10.1016/j.jare.2016.07.002. Epub 2016 Jul 14.

An MS-based metabolomic approach was used to profile the secondary metabolite of the ornamental plant Erythrina lysistemon via ultra-performance liquid chromatography coupled to photodiode array detection and high resolution q-TOF mass spectrometry (UPLC-PDA-MS). Cultures maintained the capacity to produce...

Showing 13 to 24 of 4320 entries