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Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling.

Experimental and therapeutic medicine

Zhou N, Zhu Y, Zhang P, Zhang YU, Zhou M, Wang T, He L.
PMID: 27168797
Exp Ther Med. 2016 May;11(5):1748-1754. doi: 10.3892/etm.2016.3172. Epub 2016 Mar 15.

Chronic hypertension induces vascular and cardiac remodeling. OW1 is a novel imperatorin derivative that was previously reported to inhibit vascular remodeling and improve kidney function affected by hypertension. In the present study, the effect of OW1 on the cardiac...

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Zhou N, Zhu Y, Zhang P, et al. Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling. Exp Ther Med. 2016;11(5):1748-1754doi: 10.3892/etm.2016.3172.
Zhou, N., Zhu, Y., Zhang, P., Zhang, Y. U., Zhou, M., Wang, T., & He, L. (2016). Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling. Experimental and therapeutic medicine, 11(5), 1748-1754. https://doi.org/10.3892/etm.2016.3172
Zhou, Nan, et al. "Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling." Experimental and therapeutic medicine vol. 11,5 (2016): 1748-1754. doi: https://doi.org/10.3892/etm.2016.3172
Zhou N, Zhu Y, Zhang P, Zhang YU, Zhou M, Wang T, He L. Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling. Exp Ther Med. 2016 May;11(5):1748-1754. doi: 10.3892/etm.2016.3172. Epub 2016 Mar 15. PMID: 27168797; PMCID: PMC4840669.
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(1)H NMR- based metabolomics approaches as non- invasive tools for diagnosis of endometriosis.

International journal of reproductive biomedicine

Ghazi N, Arjmand M, Akbari Z, Mellati AO, Saheb-Kashaf H, Zamani Z.
PMID: 27141542
Int J Reprod Biomed. 2016 Jan;14(1):1-8.

BACKGROUND: So far, non-invasive diagnostic approaches such as ultrasound, magnetic resonance imaging, or blood tests do not have sufficient diagnostic power for endometriosis disease. Lack of a non-invasive diagnostic test contributes to the long delay between onset of symptoms...

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Ghazi N, Arjmand M, Akbari Z, et al. (1)H NMR- based metabolomics approaches as non- invasive tools for diagnosis of endometriosis. Int J Reprod Biomed. 2016;14(1):1-8
Ghazi, N., Arjmand, M., Akbari, Z., Mellati, A. O., Saheb-Kashaf, H., & Zamani, Z. (2016). (1)H NMR- based metabolomics approaches as non- invasive tools for diagnosis of endometriosis. International journal of reproductive biomedicine, 14(1), 1-8.
Ghazi, Negar, et al. "(1)H NMR- based metabolomics approaches as non- invasive tools for diagnosis of endometriosis." International journal of reproductive biomedicine vol. 14,1 (2016): 1-8.
Ghazi N, Arjmand M, Akbari Z, Mellati AO, Saheb-Kashaf H, Zamani Z. (1)H NMR- based metabolomics approaches as non- invasive tools for diagnosis of endometriosis. Int J Reprod Biomed. 2016 Jan;14(1):1-8. PMID: 27141542; PMCID: PMC4837922.
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Clinical and laboratory determinants of low serum level of 25-hydroxyvitamin D during escalation of pharmacotherapy in heart failure patients.

Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

Myrda K, Rozentryt P, Niedziela JT, Ociessa A, Kasperova M, Hudzik B, Nowak JU, Gąsior M.
PMID: 26702277
Kardiochir Torakochirurgia Pol. 2015 Sep;12(3):216-27. doi: 10.5114/kitp.2015.54457. Epub 2015 Sep 28.

INTRODUCTION: The activation of the renin-angiotensin-aldosterone (RAA) system is a main element of the pathophysiology of chronic heart failure (CHF), determining its symptoms and prognosis. Vitamin D is an RAA inhibitor, and its deficiency frequently accompanies CHF. The factors...

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Myrda K, Rozentryt P, Niedziela JT, et al. Clinical and laboratory determinants of low serum level of 25-hydroxyvitamin D during escalation of pharmacotherapy in heart failure patients. Kardiochir Torakochirurgia Pol. 2015;12(3):216-27doi: 10.5114/kitp.2015.54457.
Myrda, K., Rozentryt, P., Niedziela, J. T., Ociessa, A., Kasperova, M., Hudzik, B., Nowak, J. U., & Gąsior, M. (2015). Clinical and laboratory determinants of low serum level of 25-hydroxyvitamin D during escalation of pharmacotherapy in heart failure patients. Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 12(3), 216-27. https://doi.org/10.5114/kitp.2015.54457
Myrda, Krzysztof, et al. "Clinical and laboratory determinants of low serum level of 25-hydroxyvitamin D during escalation of pharmacotherapy in heart failure patients." Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery vol. 12,3 (2015): 216-27. doi: https://doi.org/10.5114/kitp.2015.54457
Myrda K, Rozentryt P, Niedziela JT, Ociessa A, Kasperova M, Hudzik B, Nowak JU, Gąsior M. Clinical and laboratory determinants of low serum level of 25-hydroxyvitamin D during escalation of pharmacotherapy in heart failure patients. Kardiochir Torakochirurgia Pol. 2015 Sep;12(3):216-27. doi: 10.5114/kitp.2015.54457. Epub 2015 Sep 28. PMID: 26702277; PMCID: PMC4631913.
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Evolving role for mineralocorticoid receptor antagonists in heart failure with preserved ejection fraction.

Current opinion in cardiology

Miller RJH, Howlett JG.
PMID: 25574896
Curr Opin Cardiol. 2015 Mar;30(2):168-172. doi: 10.1097/HCO.0000000000000147.

PURPOSE OF REVIEW: The majority of randomized clinical trials in heart failure with preserved ejection fraction (HFpEF) have failed to show meaningful improvements in clinical outcomes. Recent randomized trials have shown benefits from mineralocorticoid receptor antagonists (MRAs) in the...

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Miller RJH, Howlett JG. Evolving role for mineralocorticoid receptor antagonists in heart failure with preserved ejection fraction. Curr Opin Cardiol. 2015;30(2):168-172doi: 10.1097/HCO.0000000000000147.
Miller, R. J. H., & Howlett, J. G. (2015). Evolving role for mineralocorticoid receptor antagonists in heart failure with preserved ejection fraction. Current opinion in cardiology, 30(2), 168-172. https://doi.org/10.1097/HCO.0000000000000147
Miller, Robert J H, and Howlett, Jonathan G. "Evolving role for mineralocorticoid receptor antagonists in heart failure with preserved ejection fraction." Current opinion in cardiology vol. 30,2 (2015): 168-172. doi: https://doi.org/10.1097/HCO.0000000000000147
Miller RJH, Howlett JG. Evolving role for mineralocorticoid receptor antagonists in heart failure with preserved ejection fraction. Curr Opin Cardiol. 2015 Mar;30(2):168-172. doi: 10.1097/HCO.0000000000000147. PMID: 25574896.
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Overview of the genetic determinants of primary aldosteronism.

The application of clinical genetics

Al-Salameh A, Cohen R, Desailloud R.
PMID: 24817817
Appl Clin Genet. 2014 Apr 08;7:67-79. doi: 10.2147/TACG.S45620. eCollection 2014.

Primary aldosteronism is the most common cause of secondary hypertension. The syndrome accounts for 10% of all cases of hypertension and is primarily caused by bilateral adrenal hyperplasia or aldosterone-producing adenoma. Over the last few years, the use of...

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Al-Salameh A, Cohen R, Desailloud R. Overview of the genetic determinants of primary aldosteronism. Appl Clin Genet. 2014;7:67-79doi: 10.2147/TACG.S45620.
Al-Salameh, A., Cohen, R., & Desailloud, R. (2014). Overview of the genetic determinants of primary aldosteronism. The application of clinical genetics, 767-79. https://doi.org/10.2147/TACG.S45620
Al-Salameh, Abdallah, et al. "Overview of the genetic determinants of primary aldosteronism." The application of clinical genetics vol. 7 (2014): 67-79. doi: https://doi.org/10.2147/TACG.S45620
Al-Salameh A, Cohen R, Desailloud R. Overview of the genetic determinants of primary aldosteronism. Appl Clin Genet. 2014 Apr 08;7:67-79. doi: 10.2147/TACG.S45620. eCollection 2014. PMID: 24817817; PMCID: PMC4012345.
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Association of NT-proBNP with plasma renin activity and plasma aldosterone concentration in women with singleton pregnancy.

Pregnancy hypertension

Yamada T, Koyama T, Furuta I, Takeda M, Nishida R, Yamada T, Morikawa M, Minakami H.
PMID: 26104250
Pregnancy Hypertens. 2014 Jan;4(1):23-8. doi: 10.1016/j.preghy.2013.08.002. Epub 2013 Sep 04.

OBJECTIVE: To determine the association of the N-terminal fragment of precursor protein brain-type natriuretic peptide (NT-proBNP) levels with plasma renin activity (PRA) and plasma aldosterone concentration (PAC) in singleton pregnancies.DESIGN: Serum NT-proBNP levels, PRA and PAC were determined in...

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Yamada T, Koyama T, Furuta I, et al. Association of NT-proBNP with plasma renin activity and plasma aldosterone concentration in women with singleton pregnancy. Pregnancy Hypertens. 2013;4(1):23-8doi: 10.1016/j.preghy.2013.08.002.
Yamada, T., Koyama, T., Furuta, I., Takeda, M., Nishida, R., Yamada, T., Morikawa, M., & Minakami, H. (2014). Association of NT-proBNP with plasma renin activity and plasma aldosterone concentration in women with singleton pregnancy. Pregnancy hypertension, 4(1), 23-8. https://doi.org/10.1016/j.preghy.2013.08.002
Yamada, Takashi, et al. "Association of NT-proBNP with plasma renin activity and plasma aldosterone concentration in women with singleton pregnancy." Pregnancy hypertension vol. 4,1 (2014): 23-8. doi: https://doi.org/10.1016/j.preghy.2013.08.002
Yamada T, Koyama T, Furuta I, Takeda M, Nishida R, Yamada T, Morikawa M, Minakami H. Association of NT-proBNP with plasma renin activity and plasma aldosterone concentration in women with singleton pregnancy. Pregnancy Hypertens. 2014 Jan;4(1):23-8. doi: 10.1016/j.preghy.2013.08.002. Epub 2013 Sep 04. PMID: 26104250.
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In-hospital treatment and outcomes of heart failure in specialist and non-specialist services: a retrospective cohort study in the elderly.

Open heart

Parmar KR, Xiu PY, Chowdhury MR, Patel E, Cohen M.
PMID: 26019879
Open Heart. 2015 May 21;2(1):e000095. doi: 10.1136/openhrt-2014-000095. eCollection 2015.

BACKGROUND: Heart failure is common in the elderly and is associated with high rates of hospitalisation, readmission and mortality. International guidelines however are not frequently implemented in this population.METHODS: We retrospectively studied the clinical profile, investigations, treatment on discharge,...

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Parmar KR, Xiu PY, Chowdhury MR, et al. In-hospital treatment and outcomes of heart failure in specialist and non-specialist services: a retrospective cohort study in the elderly. Open Heart. 2015;2(1):e000095doi: 10.1136/openhrt-2014-000095.
Parmar, K. R., Xiu, P. Y., Chowdhury, M. R., Patel, E., & Cohen, M. (2015). In-hospital treatment and outcomes of heart failure in specialist and non-specialist services: a retrospective cohort study in the elderly. Open heart, 2(1), e000095. https://doi.org/10.1136/openhrt-2014-000095
Parmar, Kishan R, et al. "In-hospital treatment and outcomes of heart failure in specialist and non-specialist services: a retrospective cohort study in the elderly." Open heart vol. 2,1 (2015): e000095. doi: https://doi.org/10.1136/openhrt-2014-000095
Parmar KR, Xiu PY, Chowdhury MR, Patel E, Cohen M. In-hospital treatment and outcomes of heart failure in specialist and non-specialist services: a retrospective cohort study in the elderly. Open Heart. 2015 May 21;2(1):e000095. doi: 10.1136/openhrt-2014-000095. eCollection 2015. PMID: 26019879; PMCID: PMC4442175.
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Case report: a rare cause of metabolic alkalosis.

NDT plus

Titan SM, Gebara OC, Callas SH, Hoff AO, Hoff PM, Galvão PC.
PMID: 25984146
NDT Plus. 2011 Jun;4(3):164-6. doi: 10.1093/ndtplus/sfr036. Epub 2011 Mar 29.

A case of a 66-year-old white man with recent onset of oedema, hypertension, metabolic alkalosis and profound hypokalaemia is described. The initial laboratorial workup showed that urinary chloride concentration and potassium excretion were increased, suggesting a state of hyperaldosteronism....

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Titan SM, Gebara OC, Callas SH, et al. Case report: a rare cause of metabolic alkalosis. NDT Plus. 2011;4(3):164-6doi: 10.1093/ndtplus/sfr036.
Titan, S. M., Gebara, O. C., Callas, S. H., Hoff, A. O., Hoff, P. M., & Galvão, P. C. (2011). Case report: a rare cause of metabolic alkalosis. NDT plus, 4(3), 164-6. https://doi.org/10.1093/ndtplus/sfr036
Titan, Silvia M, et al. "Case report: a rare cause of metabolic alkalosis." NDT plus vol. 4,3 (2011): 164-6. doi: https://doi.org/10.1093/ndtplus/sfr036
Titan SM, Gebara OC, Callas SH, Hoff AO, Hoff PM, Galvão PC. Case report: a rare cause of metabolic alkalosis. NDT Plus. 2011 Jun;4(3):164-6. doi: 10.1093/ndtplus/sfr036. Epub 2011 Mar 29. PMID: 25984146; PMCID: PMC4421598.
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The relationship between vitamin D deficiency and coronary artery ectasia.

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

Demir M, Demir C, Keçeoğlu S.
PMID: 25489316
Postepy Kardiol Interwencyjnej. 2014;10(4):238-41. doi: 10.5114/pwki.2014.46764. Epub 2014 Nov 17.

INTRODUCTION: The pathophysiology of coronary artery ectasia (CAE) has not been clearly identified although multiple abnormalities including arteritis, endothelial dysfunction, and atherothrombosis have been reported. The role of vitamin D deficiency suggests cardiovascular diseases such as coronary artery disease,...

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Demir M, Demir C, Keçeoğlu S. The relationship between vitamin D deficiency and coronary artery ectasia. Postepy Kardiol Interwencyjnej. 2014;10(4):238-41doi: 10.5114/pwki.2014.46764.
Demir, M., Demir, C., & Keçeoğlu, S. (2014). The relationship between vitamin D deficiency and coronary artery ectasia. Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 10(4), 238-41. https://doi.org/10.5114/pwki.2014.46764
Demir, Mehmet, et al. "The relationship between vitamin D deficiency and coronary artery ectasia." Postepy w kardiologii interwencyjnej = Advances in interventional cardiology vol. 10,4 (2014): 238-41. doi: https://doi.org/10.5114/pwki.2014.46764
Demir M, Demir C, Keçeoğlu S. The relationship between vitamin D deficiency and coronary artery ectasia. Postepy Kardiol Interwencyjnej. 2014;10(4):238-41. doi: 10.5114/pwki.2014.46764. Epub 2014 Nov 17. PMID: 25489316; PMCID: PMC4252320.
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Efficacy of lycopene on modulation of renal antioxidant enzymes, ACE and ACE gene expression in hyperlipidaemic rats.

Journal of the renin-angiotensin-aldosterone system : JRAAS

Khan NI, Noori S, Mahboob T.
PMID: 27678388
J Renin Angiotensin Aldosterone Syst. 2016 Sep 27;17(3). doi: 10.1177/1470320316664611. Print 2016 Jul.

INTRODUCTION: We aimed to evaluate the efficacy of lycopene on renal tissue antioxidant enzymes and angiotensin converting enzyme (ACE) gene expression and serum activity in diet-induced hyperlipidaemia.METHODS: Thirty-two female Wistar albino rats (200-250 g weight), 5-6 months of age,...

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Khan NI, Noori S, Mahboob T. Efficacy of lycopene on modulation of renal antioxidant enzymes, ACE and ACE gene expression in hyperlipidaemic rats. J Renin Angiotensin Aldosterone Syst. 2016;17(3)doi: 10.1177/1470320316664611.
Khan, N. I., Noori, S., & Mahboob, T. (2016). Efficacy of lycopene on modulation of renal antioxidant enzymes, ACE and ACE gene expression in hyperlipidaemic rats. Journal of the renin-angiotensin-aldosterone system : JRAAS, 17(3), . https://doi.org/10.1177/1470320316664611
Khan, Nazish Iqbal, et al. "Efficacy of lycopene on modulation of renal antioxidant enzymes, ACE and ACE gene expression in hyperlipidaemic rats." Journal of the renin-angiotensin-aldosterone system : JRAAS vol. 17,3 (2016). doi: https://doi.org/10.1177/1470320316664611
Khan NI, Noori S, Mahboob T. Efficacy of lycopene on modulation of renal antioxidant enzymes, ACE and ACE gene expression in hyperlipidaemic rats. J Renin Angiotensin Aldosterone Syst. 2016 Sep 27;17(3). doi: 10.1177/1470320316664611. Print 2016 Jul. PMID: 27678388; PMCID: PMC5843852.
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Vitamin D3 May Ameliorate the Ketoconazole Induced Adrenal Injury: Histological and Immunohistochemical Studies on Albino Rats.

Acta histochemica et cytochemica

Khalil MS.
PMID: 26379312
Acta Histochem Cytochem. 2015 Aug 27;48(4):103-13. doi: 10.1267/ahc.14062. Epub 2015 Aug 20.

Ketoconazole (KZ) is used widely for treating the superficial, systemic fungal activities and hyperandrogenemic states. Its uses are limited by its deleterious effect on histological structure and function of the adrenal cortex. This study investigates whether vitamin D3 supplement...

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Khalil MS. Vitamin D3 May Ameliorate the Ketoconazole Induced Adrenal Injury: Histological and Immunohistochemical Studies on Albino Rats. Acta Histochem Cytochem. 2015;48(4):103-13doi: 10.1267/ahc.14062.
Khalil, M. S. (2015). Vitamin D3 May Ameliorate the Ketoconazole Induced Adrenal Injury: Histological and Immunohistochemical Studies on Albino Rats. Acta histochemica et cytochemica, 48(4), 103-13. https://doi.org/10.1267/ahc.14062
Khalil, Mahmoud Salah. "Vitamin D3 May Ameliorate the Ketoconazole Induced Adrenal Injury: Histological and Immunohistochemical Studies on Albino Rats." Acta histochemica et cytochemica vol. 48,4 (2015): 103-13. doi: https://doi.org/10.1267/ahc.14062
Khalil MS. Vitamin D3 May Ameliorate the Ketoconazole Induced Adrenal Injury: Histological and Immunohistochemical Studies on Albino Rats. Acta Histochem Cytochem. 2015 Aug 27;48(4):103-13. doi: 10.1267/ahc.14062. Epub 2015 Aug 20. PMID: 26379312; PMCID: PMC4564376.
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A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development.

BMC nephrology

Khandelwal A, Trinkaus MA, Ghaffar H, Jothy S, Goldstein MB.
PMID: 27686684
BMC Nephrol. 2016 Sep 29;17(1):140. doi: 10.1186/s12882-016-0349-9.

BACKGROUND: Immunotactoid glomerulopathy (ITG) is a rare cause of proteinuria characterized by organized microtubular deposits in the glomerulus. ITG has been associated with underlying lymphoproliferative disorders and any renal impairment may be reversible with treatment of the concomitant hematologic...

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Khandelwal A, Trinkaus MA, Ghaffar H, et al. A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development. BMC Nephrol. 2016;17(1):140doi: 10.1186/s12882-016-0349-9.
Khandelwal, A., Trinkaus, M. A., Ghaffar, H., Jothy, S., & Goldstein, M. B. (2016). A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development. BMC nephrology, 17(1), 140. https://doi.org/10.1186/s12882-016-0349-9
Khandelwal, Aditi, et al. "A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development." BMC nephrology vol. 17,1 (2016): 140. doi: https://doi.org/10.1186/s12882-016-0349-9
Khandelwal A, Trinkaus MA, Ghaffar H, Jothy S, Goldstein MB. A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development. BMC Nephrol. 2016 Sep 29;17(1):140. doi: 10.1186/s12882-016-0349-9. PMID: 27686684; PMCID: PMC5043628.
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