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Showing 25 to 36 of 224 entries
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Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence.

Scientific reports

Hsieh K, Wang Y, Chen L, Zhao Z, Savitz S, Jiang X, Tang J, Kim Y.
PMID: 34848761
Sci Rep. 2021 Nov 30;11(1):23179. doi: 10.1038/s41598-021-02353-5.

Since the 2019 novel coronavirus disease (COVID-19) outbreak in 2019 and the pandemic continues for more than one year, a vast amount of drug research has been conducted and few of them got FDA approval. Our objective is to...

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Hsieh K, Wang Y, Chen L, et al. Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence. Sci Rep. 2021;11(1):23179doi: 10.1038/s41598-021-02353-5.
Hsieh, K., Wang, Y., Chen, L., Zhao, Z., Savitz, S., Jiang, X., Tang, J., & Kim, Y. (2021). Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence. Scientific reports, 11(1), 23179. https://doi.org/10.1038/s41598-021-02353-5
Hsieh, Kanglin, et al. "Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence." Scientific reports vol. 11,1 (2021): 23179. doi: https://doi.org/10.1038/s41598-021-02353-5
Hsieh K, Wang Y, Chen L, Zhao Z, Savitz S, Jiang X, Tang J, Kim Y. Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence. Sci Rep. 2021 Nov 30;11(1):23179. doi: 10.1038/s41598-021-02353-5. PMID: 34848761; PMCID: PMC8632883.
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The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department.

Pediatric emergency care

Adair E, Dibaba D, Fowke JH, Snider M.
PMID: 33136831
Pediatr Emerg Care. 2022 Jan 01;38(1):e292-e294. doi: 10.1097/PEC.0000000000002269.

METHODS: Patients were identified using a retrospective cohort analysis from a single, tertiary care, urban children's hospital. Patients presenting directly to our emergency department aged 2 to 18 years were included if they had a diagnosis of severe asthma...

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Adair E, Dibaba D, Fowke JH, et al. The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department. Pediatr Emerg Care. 2022;38(1):e292-e294doi: 10.1097/PEC.0000000000002269.
Adair, E., Dibaba, D., Fowke, J. H., & Snider, M. (2022). The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department. Pediatric emergency care, 38(1), e292-e294. https://doi.org/10.1097/PEC.0000000000002269
Adair, Erik, et al. "The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department." Pediatric emergency care vol. 38,1 (2022): e292-e294. doi: https://doi.org/10.1097/PEC.0000000000002269
Adair E, Dibaba D, Fowke JH, Snider M. The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department. Pediatr Emerg Care. 2022 Jan 01;38(1):e292-e294. doi: 10.1097/PEC.0000000000002269. PMID: 33136831.
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Dexmedetomidine as an adjunctive treatment for acute asthma.

Clinical and experimental emergency medicine

Motamed H, Forouzan A, Moezzi M, Alizadeh H.
PMID: 34237813
Clin Exp Emerg Med. 2021 Jun;8(2):89-93. doi: 10.15441/ceem.20.038. Epub 2021 Jun 30.

OBJECTIVE: This study aimed to compare the efficacy of using dexmedetomidine with salbutamol and salbutamol nebulization alone in patients with acute exacerbation of asthma presenting to the emergency department.METHODS: This clinical trial included 60 patients, in the age range...

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Motamed H, Forouzan A, Moezzi M, et al. Dexmedetomidine as an adjunctive treatment for acute asthma. Clin Exp Emerg Med. 2021;8(2):89-93doi: 10.15441/ceem.20.038.
Motamed, H., Forouzan, A., Moezzi, M., & Alizadeh, H. (2021). Dexmedetomidine as an adjunctive treatment for acute asthma. Clinical and experimental emergency medicine, 8(2), 89-93. https://doi.org/10.15441/ceem.20.038
Motamed, Hassan, et al. "Dexmedetomidine as an adjunctive treatment for acute asthma." Clinical and experimental emergency medicine vol. 8,2 (2021): 89-93. doi: https://doi.org/10.15441/ceem.20.038
Motamed H, Forouzan A, Moezzi M, Alizadeh H. Dexmedetomidine as an adjunctive treatment for acute asthma. Clin Exp Emerg Med. 2021 Jun;8(2):89-93. doi: 10.15441/ceem.20.038. Epub 2021 Jun 30. PMID: 34237813; PMCID: PMC8273673.
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Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study.

BMJ open respiratory research

Chipps BE, Albers FC, Reilly L, Johnsson E, Cappelletti C, Papi A.
PMID: 34887317
BMJ Open Respir Res. 2021 Dec;8(1). doi: 10.1136/bmjresp-2021-001077.

INTRODUCTION: Uncontrolled asthma is associated with substantial morbidity. While fast-acting bronchodilators provide quick relief from asthma symptoms, their use as rescue fails to address the underlying inflammation. Combining a short-acting betaMETHODS AND ANALYSIS: The Phase 3 MANDALA study was...

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Chipps BE, Albers FC, Reilly L, et al. Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study. BMJ Open Respir Res. 2021;8(1)doi: 10.1136/bmjresp-2021-001077.
Chipps, B. E., Albers, F. C., Reilly, L., Johnsson, E., Cappelletti, C., & Papi, A. (2021). Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study. BMJ open respiratory research, 8(1), . https://doi.org/10.1136/bmjresp-2021-001077
Chipps, Bradley E, et al. "Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study." BMJ open respiratory research vol. 8,1 (2021). doi: https://doi.org/10.1136/bmjresp-2021-001077
Chipps BE, Albers FC, Reilly L, Johnsson E, Cappelletti C, Papi A. Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study. BMJ Open Respir Res. 2021 Dec;8(1). doi: 10.1136/bmjresp-2021-001077. PMID: 34887317.
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Implementation of a Nurse-Driven Asthma Pathway in the Pediatric Intensive Care Unit.

Pediatric quality & safety

Flaherty MR, Whalen K, Lee J, Duran C, Alshareef O, Yager P, Cummings B.
PMID: 34934882
Pediatr Qual Saf. 2021 Dec 15;6(6):e503. doi: 10.1097/pq9.0000000000000503. eCollection 2021.

Asthma is one of the most common conditions requiring admission to a pediatric intensive care unit. Dosing and weaning medications, particularly bronchodilators, are highly variable, and evidence-based weaning algorithms for clinicians are lacking in this setting.METHODS: Patients admitted to...

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Flaherty MR, Whalen K, Lee J, et al. Implementation of a Nurse-Driven Asthma Pathway in the Pediatric Intensive Care Unit. Pediatr Qual Saf. 2021;6(6):e503doi: 10.1097/pq9.0000000000000503.
Flaherty, M. R., Whalen, K., Lee, J., Duran, C., Alshareef, O., Yager, P., & Cummings, B. (2021). Implementation of a Nurse-Driven Asthma Pathway in the Pediatric Intensive Care Unit. Pediatric quality & safety, 6(6), e503. https://doi.org/10.1097/pq9.0000000000000503
Flaherty, Michael R, et al. "Implementation of a Nurse-Driven Asthma Pathway in the Pediatric Intensive Care Unit." Pediatric quality & safety vol. 6,6 (2021): e503. doi: https://doi.org/10.1097/pq9.0000000000000503
Flaherty MR, Whalen K, Lee J, Duran C, Alshareef O, Yager P, Cummings B. Implementation of a Nurse-Driven Asthma Pathway in the Pediatric Intensive Care Unit. Pediatr Qual Saf. 2021 Dec 15;6(6):e503. doi: 10.1097/pq9.0000000000000503. eCollection 2021. PMID: 34934882; PMCID: PMC8677970.
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A 31-Year-Old Pregnant Woman With Asthma, Presenting With Worsening Dyspnea, Wheeze, and Hoarseness.

Chest

Okereke J, Malin M, Koo P.
PMID: 34743854
Chest. 2021 Nov;160(5):e507-e512. doi: 10.1016/j.chest.2021.06.064.

CASE PRESENTATION: A 31-year-old woman (gravida 3 and para 1-0-1-1 at 20 weeks gestation) was admitted to the hospital for a presumed acute asthma exacerbation. She had a history of severe persistent asthma since childhood. She described her symptoms...

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Okereke J, Malin M, Koo P. A 31-Year-Old Pregnant Woman With Asthma, Presenting With Worsening Dyspnea, Wheeze, and Hoarseness. Chest. 2021;160(5):e507-e512doi: 10.1016/j.chest.2021.06.064.
Okereke, J., Malin, M., & Koo, P. (2021). A 31-Year-Old Pregnant Woman With Asthma, Presenting With Worsening Dyspnea, Wheeze, and Hoarseness. Chest, 160(5), e507-e512. https://doi.org/10.1016/j.chest.2021.06.064
Okereke, Jetina, et al. "A 31-Year-Old Pregnant Woman With Asthma, Presenting With Worsening Dyspnea, Wheeze, and Hoarseness." Chest vol. 160,5 (2021): e507-e512. doi: https://doi.org/10.1016/j.chest.2021.06.064
Okereke J, Malin M, Koo P. A 31-Year-Old Pregnant Woman With Asthma, Presenting With Worsening Dyspnea, Wheeze, and Hoarseness. Chest. 2021 Nov;160(5):e507-e512. doi: 10.1016/j.chest.2021.06.064. PMID: 34743854.
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Noninvasive ventilation use in pediatric status asthmaticus.

The Journal of asthma : official journal of the Association for the Care of Asthma

Usala C, Wilson P.
PMID: 34111361
J Asthma. 2021 Jun 18;1-5. doi: 10.1080/02770903.2021.1941085. Epub 2021 Jun 18.

INTRODUCTION: Noninvasive ventilation (NIV) is sometimes used in refractory pediatric status asthmaticus for its potential benefits of stenting airways and dispersing albuterol. However, its effectiveness in pediatric asthma remains unproven. The usage pattern, outcomes, and safety of NIV in...

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Usala C, Wilson P. Noninvasive ventilation use in pediatric status asthmaticus. J Asthma. 2021;1-5doi: 10.1080/02770903.2021.1941085.
Usala, C., & Wilson, P. (2021). Noninvasive ventilation use in pediatric status asthmaticus. The Journal of asthma : official journal of the Association for the Care of Asthma, 1-5. https://doi.org/10.1080/02770903.2021.1941085
Usala, Claire, and Wilson, Patrick. "Noninvasive ventilation use in pediatric status asthmaticus." The Journal of asthma : official journal of the Association for the Care of Asthma vol. (2021): 1-5. doi: https://doi.org/10.1080/02770903.2021.1941085
Usala C, Wilson P. Noninvasive ventilation use in pediatric status asthmaticus. J Asthma. 2021 Jun 18;1-5. doi: 10.1080/02770903.2021.1941085. Epub 2021 Jun 18. PMID: 34111361.
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Acute and durable effect of inhaled hypertonic saline on mucociliary clearance in adult asthma.

ERJ open research

Bennett WD, Burbank A, Almond M, Wu J, Ceppe A, Hernandez M, Boucher RC, Peden DB.
PMID: 34109248
ERJ Open Res. 2021 Jun 07;7(2). doi: 10.1183/23120541.00062-2021. eCollection 2021 Apr.

BACKGROUND: Impaired mucus clearance and airway mucus plugging have been shown to occur in moderate-severe asthma, especially during acute exacerbations. In cystic fibrosis, where airway mucus is dehydrated, it has been shown that inhaled hypertonic saline (HS) produces both...

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Bennett WD, Burbank A, Almond M, et al. Acute and durable effect of inhaled hypertonic saline on mucociliary clearance in adult asthma. ERJ Open Res. 2021;7(2)doi: 10.1183/23120541.00062-2021.
Bennett, W. D., Burbank, A., Almond, M., Wu, J., Ceppe, A., Hernandez, M., Boucher, R. C., & Peden, D. B. (2021). Acute and durable effect of inhaled hypertonic saline on mucociliary clearance in adult asthma. ERJ open research, 7(2), . https://doi.org/10.1183/23120541.00062-2021
Bennett, William D, et al. "Acute and durable effect of inhaled hypertonic saline on mucociliary clearance in adult asthma." ERJ open research vol. 7,2 (2021). doi: https://doi.org/10.1183/23120541.00062-2021
Bennett WD, Burbank A, Almond M, Wu J, Ceppe A, Hernandez M, Boucher RC, Peden DB. Acute and durable effect of inhaled hypertonic saline on mucociliary clearance in adult asthma. ERJ Open Res. 2021 Jun 07;7(2). doi: 10.1183/23120541.00062-2021. eCollection 2021 Apr. PMID: 34109248; PMCID: PMC8184161.
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Prescriptions from Traditional Chinese Medicine compared with salbutamol and montelukast for the treatment of pediatric asthma: a randomized controlled trial.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

Du H, Wang Y, Yu J, Shi Y, Li S, Sun W, Zhang Y, Hu H.
PMID: 32188211
J Tradit Chin Med. 2017 Aug;37(4):522-529.

OBJECTIVE: To compare the effects of a series of Traditional Chinese Medicine (TCM) empirical prescriptions with salbutamol and montelukast (SM) in children with asthma.METHODS: A total of 182 children with asthma were randomized into the TCM group (n =...

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Du H, Wang Y, Yu J, et al. Prescriptions from Traditional Chinese Medicine compared with salbutamol and montelukast for the treatment of pediatric asthma: a randomized controlled trial. J Tradit Chin Med. 2017;37(4):522-529
Du, H., Wang, Y., Yu, J., Shi, Y., Li, S., Sun, W., Zhang, Y., & Hu, H. (2017). Prescriptions from Traditional Chinese Medicine compared with salbutamol and montelukast for the treatment of pediatric asthma: a randomized controlled trial. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 37(4), 522-529.
Du, Hui, et al. "Prescriptions from Traditional Chinese Medicine compared with salbutamol and montelukast for the treatment of pediatric asthma: a randomized controlled trial." Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan vol. 37,4 (2017): 522-529.
Du H, Wang Y, Yu J, Shi Y, Li S, Sun W, Zhang Y, Hu H. Prescriptions from Traditional Chinese Medicine compared with salbutamol and montelukast for the treatment of pediatric asthma: a randomized controlled trial. J Tradit Chin Med. 2017 Aug;37(4):522-529. PMID: 32188211.
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Respiratory diseases in patients with bed bugs.

The clinical respiratory journal

Sheele JM.
PMID: 34498401
Clin Respir J. 2021 Sep 08; doi: 10.1111/crj.13447. Epub 2021 Sep 08.

INTRODUCTION: Some arthropods such as cockroaches can exacerbate asthma, but it is unknown is this is true of bed bugs.OBJECTIVES: The objective of this work is to determine if bronchospastic diseases like asthma and chronic obstructive pulmonary disease (COPD)...

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Sheele JM. Respiratory diseases in patients with bed bugs. Clin Respir J. 2021;doi: 10.1111/crj.13447.
Sheele, J. M. (2021). Respiratory diseases in patients with bed bugs. The clinical respiratory journal, . https://doi.org/10.1111/crj.13447
Sheele, Johnathan M. "Respiratory diseases in patients with bed bugs." The clinical respiratory journal vol. (2021). doi: https://doi.org/10.1111/crj.13447
Sheele JM. Respiratory diseases in patients with bed bugs. Clin Respir J. 2021 Sep 08; doi: 10.1111/crj.13447. Epub 2021 Sep 08. PMID: 34498401.
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Respiratory diseases in patients with bed bugs.

The clinical respiratory journal

Sheele JM.
PMID: 34498401
Clin Respir J. 2021 Sep 08; doi: 10.1111/crj.13447. Epub 2021 Sep 08.

INTRODUCTION: Some arthropods such as cockroaches can exacerbate asthma, but it is unknown is this is true of bed bugs.OBJECTIVES: The objective of this work is to determine if bronchospastic diseases like asthma and chronic obstructive pulmonary disease (COPD)...

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Sheele JM. Respiratory diseases in patients with bed bugs. Clin Respir J. 2021;doi: 10.1111/crj.13447.
Sheele, J. M. (2021). Respiratory diseases in patients with bed bugs. The clinical respiratory journal, . https://doi.org/10.1111/crj.13447
Sheele, Johnathan M. "Respiratory diseases in patients with bed bugs." The clinical respiratory journal vol. (2021). doi: https://doi.org/10.1111/crj.13447
Sheele JM. Respiratory diseases in patients with bed bugs. Clin Respir J. 2021 Sep 08; doi: 10.1111/crj.13447. Epub 2021 Sep 08. PMID: 34498401.
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Asthma Ambulatory Care Quality in Foreign-Born Latino Children in the United States.

Academic pediatrics

Heintzman J, Kaufmann J, Bailey S, Lucas J, Suglia SF, Puro J, Giebultowicz S, Ezekiel-Herrera D, Marino M.
PMID: 34688905
Acad Pediatr. 2021 Oct 22; doi: 10.1016/j.acap.2021.10.003. Epub 2021 Oct 22.

BACKGROUND: Foreign-born Latino children in the United States (US) have poor asthma outcomes, but the role of routine care utilization in these outcomes is unclear. Our objective was to compare select ambulatory care utilization measures for asthma between foreign-born...

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Heintzman J, Kaufmann J, Bailey S, et al. Asthma Ambulatory Care Quality in Foreign-Born Latino Children in the United States. Acad Pediatr. 2021;doi: 10.1016/j.acap.2021.10.003.
Heintzman, J., Kaufmann, J., Bailey, S., Lucas, J., Suglia, S. F., Puro, J., Giebultowicz, S., Ezekiel-Herrera, D., & Marino, M. (2021). Asthma Ambulatory Care Quality in Foreign-Born Latino Children in the United States. Academic pediatrics, . https://doi.org/10.1016/j.acap.2021.10.003
Heintzman, John, et al. "Asthma Ambulatory Care Quality in Foreign-Born Latino Children in the United States." Academic pediatrics vol. (2021). doi: https://doi.org/10.1016/j.acap.2021.10.003
Heintzman J, Kaufmann J, Bailey S, Lucas J, Suglia SF, Puro J, Giebultowicz S, Ezekiel-Herrera D, Marino M. Asthma Ambulatory Care Quality in Foreign-Born Latino Children in the United States. Acad Pediatr. 2021 Oct 22; doi: 10.1016/j.acap.2021.10.003. Epub 2021 Oct 22. PMID: 34688905.
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Showing 25 to 36 of 224 entries