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Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Bayes M, Rabasseda X, Prous JR.
PMID: 16082427
Methods Find Exp Clin Pharmacol. 2005 May;27(4):265-84.

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug...

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Bayes M, Rabasseda X, Prous JR. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2005;27(4):265-84
Bayes, M., Rabasseda, X., & Prous, J. R. (2005). Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology, 27(4), 265-84.
Bayes, M, et al. "Gateways to clinical trials." Methods and findings in experimental and clinical pharmacology vol. 27,4 (2005): 265-84.
Bayes M, Rabasseda X, Prous JR. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2005 May;27(4):265-84. PMID: 16082427.
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Dobutamine stress test and beta-agonist - a potential concern for nuclear cardiology testing: a case report.

Cases journal

Ozcan C, Zaret BL.
PMID: 19829971
Cases J. 2009 Jul 09;2:7466. doi: 10.4076/1757-1626-2-7466.

INTRODUCTION: Chest pain with ST-segment elevation is a rare clinical problem during dobutamine stress testing. Although beta-agonists treatment prior to dobutamine stress testing has been shown to reduce the duration and amount of dobutamine infusion and atropine requirement, there...

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Ozcan C, Zaret BL. Dobutamine stress test and beta-agonist - a potential concern for nuclear cardiology testing: a case report. Cases J. 2009;2:7466doi: 10.4076/1757-1626-2-7466.
Ozcan, C., & Zaret, B. L. (2009). Dobutamine stress test and beta-agonist - a potential concern for nuclear cardiology testing: a case report. Cases journal, 27466. https://doi.org/10.4076/1757-1626-2-7466
Ozcan, Cevher, and Zaret, Barry L. "Dobutamine stress test and beta-agonist - a potential concern for nuclear cardiology testing: a case report." Cases journal vol. 2 (2009): 7466. doi: https://doi.org/10.4076/1757-1626-2-7466
Ozcan C, Zaret BL. Dobutamine stress test and beta-agonist - a potential concern for nuclear cardiology testing: a case report. Cases J. 2009 Jul 09;2:7466. doi: 10.4076/1757-1626-2-7466. PMID: 19829971; PMCID: PMC2740317.
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Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates.

Journal of asthma and allergy

Wang X, Reece S, Olmstead S, Wardle RL, Van Scott MR.
PMID: 21437042
J Asthma Allergy. 2010 Jul 28;3:75-86. doi: 10.2147/jaa.s11781.

Nocturnal bronchoconstriction is a common symptom of asthma in humans, but is poorly documented in animal models. Thoracoabdominal asynchrony (TAA) is a noninvasive clinical indication of airway obstruction. In this study, respiratory inductive plethysmography (RIP) was used to document...

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Wang X, Reece S, Olmstead S, et al. Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates. J Asthma Allergy. 2010;3:75-86doi: 10.2147/jaa.s11781.
Wang, X., Reece, S., Olmstead, S., Wardle, R. L., & Van Scott, M. R. (2010). Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates. Journal of asthma and allergy, 375-86. https://doi.org/10.2147/jaa.s11781
Wang, Xiaojia, et al. "Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates." Journal of asthma and allergy vol. 3 (2010): 75-86. doi: https://doi.org/10.2147/jaa.s11781
Wang X, Reece S, Olmstead S, Wardle RL, Van Scott MR. Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates. J Asthma Allergy. 2010 Jul 28;3:75-86. doi: 10.2147/jaa.s11781. PMID: 21437042; PMCID: PMC3047915.
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Comparison of levalbuterol and racemic albuterol based on cardiac adverse effects in children.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Bio LL, Willey VJ, Poon CY.
PMID: 22479161
J Pediatr Pharmacol Ther. 2011 Jul;16(3):191-8. doi: 10.5863/1551-6776-16.3.191.

OBJECTIVE: To compare the cardiac effects of levalbuterol with those of racemic albuterol based on changes in heart rate (HR) in pediatric patients.METHODS: The medical records of hospitalized children ages 1 month to 12 years, who received either levalbuterol...

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Bio LL, Willey VJ, Poon CY. Comparison of levalbuterol and racemic albuterol based on cardiac adverse effects in children. J Pediatr Pharmacol Ther. 2011;16(3):191-8doi: 10.5863/1551-6776-16.3.191.
Bio, L. L., Willey, V. J., & Poon, C. Y. (2011). Comparison of levalbuterol and racemic albuterol based on cardiac adverse effects in children. The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 16(3), 191-8. https://doi.org/10.5863/1551-6776-16.3.191
Bio, Laura L, et al. "Comparison of levalbuterol and racemic albuterol based on cardiac adverse effects in children." The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG vol. 16,3 (2011): 191-8. doi: https://doi.org/10.5863/1551-6776-16.3.191
Bio LL, Willey VJ, Poon CY. Comparison of levalbuterol and racemic albuterol based on cardiac adverse effects in children. J Pediatr Pharmacol Ther. 2011 Jul;16(3):191-8. doi: 10.5863/1551-6776-16.3.191. PMID: 22479161; PMCID: PMC3292530.
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Oral curcumin supplementation in patients with atopic asthma.

Allergy & rhinology (Providence, R.I.)

Kim DH, Phillips JF, Lockey RF.
PMID: 22852117
Allergy Rhinol (Providence). 2011 Apr;2(2):e51-3. doi: 10.2500/ar.2011.2.0016.

Oral curcumin is recognized to have anti-inflammatory properties and has been used by ancient traditional medicine for centuries to treat a variety of diseases. In vitro studies have confirmed the ability of curcumin to inhibit allergic inflammatory cytokine responses...

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Kim DH, Phillips JF, Lockey RF. Oral curcumin supplementation in patients with atopic asthma. Allergy Rhinol (Providence). 2011;2(2):e51-3doi: 10.2500/ar.2011.2.0016.
Kim, D. H., Phillips, J. F., & Lockey, R. F. (2011). Oral curcumin supplementation in patients with atopic asthma. Allergy & rhinology (Providence, R.I.), 2(2), e51-3. https://doi.org/10.2500/ar.2011.2.0016
Kim, Dennis H, et al. "Oral curcumin supplementation in patients with atopic asthma." Allergy & rhinology (Providence, R.I.) vol. 2,2 (2011): e51-3. doi: https://doi.org/10.2500/ar.2011.2.0016
Kim DH, Phillips JF, Lockey RF. Oral curcumin supplementation in patients with atopic asthma. Allergy Rhinol (Providence). 2011 Apr;2(2):e51-3. doi: 10.2500/ar.2011.2.0016. PMID: 22852117; PMCID: PMC3390116.
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The metabolomics of asthma control: a promising link between genetics and disease.

Immunity, inflammation and disease

McGeachie MJ, Dahlin A, Qiu W, Croteau-Chonka DC, Savage J, Wu AC, Wan ES, Sordillo JE, Al-Garawi A, Martinez FD, Strunk RC, Lemanske RF, Liu AH, Raby BA, Weiss S, Clish CB, Lasky-Su JA.
PMID: 26421150
Immun Inflamm Dis. 2015 Sep;3(3):224-38. doi: 10.1002/iid3.61. Epub 2015 May 07.

Short-acting β agonists (e.g., albuterol) are the most commonly used medications for asthma, a disease that affects over 300 million people in the world. Metabolomic profiling of asthmatics taking β agonists presents a new and promising resource for identifying...

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McGeachie MJ, Dahlin A, Qiu W, et al. The metabolomics of asthma control: a promising link between genetics and disease. Immun Inflamm Dis. 2015;3(3):224-38doi: 10.1002/iid3.61.
McGeachie, M. J., Dahlin, A., Qiu, W., Croteau-Chonka, D. C., Savage, J., Wu, A. C., Wan, E. S., Sordillo, J. E., Al-Garawi, A., Martinez, F. D., Strunk, R. C., Lemanske, R. F., Liu, A. H., Raby, B. A., Weiss, S., Clish, C. B., & Lasky-Su, J. A. (2015). The metabolomics of asthma control: a promising link between genetics and disease. Immunity, inflammation and disease, 3(3), 224-38. https://doi.org/10.1002/iid3.61
McGeachie, Michael J, et al. "The metabolomics of asthma control: a promising link between genetics and disease." Immunity, inflammation and disease vol. 3,3 (2015): 224-38. doi: https://doi.org/10.1002/iid3.61
McGeachie MJ, Dahlin A, Qiu W, Croteau-Chonka DC, Savage J, Wu AC, Wan ES, Sordillo JE, Al-Garawi A, Martinez FD, Strunk RC, Lemanske RF, Liu AH, Raby BA, Weiss S, Clish CB, Lasky-Su JA. The metabolomics of asthma control: a promising link between genetics and disease. Immun Inflamm Dis. 2015 Sep;3(3):224-38. doi: 10.1002/iid3.61. Epub 2015 May 07. PMID: 26421150; PMCID: PMC4578522.
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Continuous Albuterol in Pediatric Acute Care: Study Demonstrates Safety Outside the Intensive Care Unit.

Pediatric quality & safety

Messer AF, Sampayo EM, Mothner B, Camp EA, Jones J, Brown T, Vachani J.
PMID: 32010852
Pediatr Qual Saf. 2019 Dec 05;4(6):e225. doi: 10.1097/pq9.0000000000000225. eCollection 2019.

There are little data to support the use of continuous aerosolized albuterol (CAA) in the non-intensive care unit (ICU) or non-emergency department (ED) setting for pediatric asthma patients. A 2014 study demonstrated low rates of adverse outcomes associated with...

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Messer AF, Sampayo EM, Mothner B, et al. Continuous Albuterol in Pediatric Acute Care: Study Demonstrates Safety Outside the Intensive Care Unit. Pediatr Qual Saf. 2019;4(6):e225doi: 10.1097/pq9.0000000000000225.
Messer, A. F., Sampayo, E. M., Mothner, B., Camp, E. A., Jones, J., Brown, T., & Vachani, J. (2019). Continuous Albuterol in Pediatric Acute Care: Study Demonstrates Safety Outside the Intensive Care Unit. Pediatric quality & safety, 4(6), e225. https://doi.org/10.1097/pq9.0000000000000225
Messer, Amanda F, et al. "Continuous Albuterol in Pediatric Acute Care: Study Demonstrates Safety Outside the Intensive Care Unit." Pediatric quality & safety vol. 4,6 (2019): e225. doi: https://doi.org/10.1097/pq9.0000000000000225
Messer AF, Sampayo EM, Mothner B, Camp EA, Jones J, Brown T, Vachani J. Continuous Albuterol in Pediatric Acute Care: Study Demonstrates Safety Outside the Intensive Care Unit. Pediatr Qual Saf. 2019 Dec 05;4(6):e225. doi: 10.1097/pq9.0000000000000225. eCollection 2019. PMID: 32010852; PMCID: PMC6946228.
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Management of Wheezy Preschoolers in the Emergency Department: A Discrete Choice Experiment.

Pediatric emergency care

Currie G, Crotts J, Nettel-Aguirre A, Johnson D, Stang A.
PMID: 30281552
Pediatr Emerg Care. 2018 Oct 02; doi: 10.1097/PEC.0000000000001577. Epub 2018 Oct 02.

OBJECTIVES: This study aimed to elicit pediatric emergency physician's treatment choices for preschool-aged children with wheeze, determine the characteristics of the presenting child that influence treatment choices, and determine whether there is clinical equipoise by eliciting physician willingness to...

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Currie G, Crotts J, Nettel-Aguirre A, et al. Management of Wheezy Preschoolers in the Emergency Department: A Discrete Choice Experiment. Pediatr Emerg Care. 2018;doi: 10.1097/PEC.0000000000001577.
Currie, G., Crotts, J., Nettel-Aguirre, A., Johnson, D., & Stang, A. (2018). Management of Wheezy Preschoolers in the Emergency Department: A Discrete Choice Experiment. Pediatric emergency care, . https://doi.org/10.1097/PEC.0000000000001577
Currie, Gillian, et al. "Management of Wheezy Preschoolers in the Emergency Department: A Discrete Choice Experiment." Pediatric emergency care vol. (2018). doi: https://doi.org/10.1097/PEC.0000000000001577
Currie G, Crotts J, Nettel-Aguirre A, Johnson D, Stang A. Management of Wheezy Preschoolers in the Emergency Department: A Discrete Choice Experiment. Pediatr Emerg Care. 2018 Oct 02; doi: 10.1097/PEC.0000000000001577. Epub 2018 Oct 02. PMID: 30281552.
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Emergency Medication Access and Administration in Schools: A Focus on Epinephrine, Albuterol Inhalers, and Glucagon.

The Journal of school nursing : the official publication of the National Association of School Nurses

McCaughey RA, McCarthy AM, Maughan E, Hein M, Perkhounkova Y, Kelly MW.
PMID: 32588714
J Sch Nurs. 2020 Jun 26;1059840520934185. doi: 10.1177/1059840520934185. Epub 2020 Jun 26.

Access to emergency medications is a growing concern, particularly regarding the availability, safety, and use of these medications in schools. The purpose of this article is to report results not previously published from a national survey, specifically regarding the...

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McCaughey RA, McCarthy AM, Maughan E, et al. Emergency Medication Access and Administration in Schools: A Focus on Epinephrine, Albuterol Inhalers, and Glucagon. J Sch Nurs. 2020;1059840520934185doi: 10.1177/1059840520934185.
McCaughey, R. A., McCarthy, A. M., Maughan, E., Hein, M., Perkhounkova, Y., & Kelly, M. W. (2020). Emergency Medication Access and Administration in Schools: A Focus on Epinephrine, Albuterol Inhalers, and Glucagon. The Journal of school nursing : the official publication of the National Association of School Nurses, 1059840520934185. https://doi.org/10.1177/1059840520934185
McCaughey, Rebecca A, et al. "Emergency Medication Access and Administration in Schools: A Focus on Epinephrine, Albuterol Inhalers, and Glucagon." The Journal of school nursing : the official publication of the National Association of School Nurses vol. (2020): 1059840520934185. doi: https://doi.org/10.1177/1059840520934185
McCaughey RA, McCarthy AM, Maughan E, Hein M, Perkhounkova Y, Kelly MW. Emergency Medication Access and Administration in Schools: A Focus on Epinephrine, Albuterol Inhalers, and Glucagon. J Sch Nurs. 2020 Jun 26;1059840520934185. doi: 10.1177/1059840520934185. Epub 2020 Jun 26. PMID: 32588714.
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The Influence of Beta-2 Adrenergic Receptor Gene Polymorphisms on Albuterol Therapy for Patients With Asthma: Protocol for a Systematic Review and Meta-Analysis.

JMIR research protocols

Hikino K, Kobayashi S, Ota E, Mushiroda T, Kobayashi T.
PMID: 31538939
JMIR Res Protoc. 2019 Sep 16;8(9):e14759. doi: 10.2196/14759.

BACKGROUND: Albuterol is one of the most frequently used medications in clinical practice and seeing varying responses to albuterol between individuals is not uncommon. Multiple studies have been conducted to investigate the associations of differing responses due to albuterol,...

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Hikino K, Kobayashi S, Ota E, et al. The Influence of Beta-2 Adrenergic Receptor Gene Polymorphisms on Albuterol Therapy for Patients With Asthma: Protocol for a Systematic Review and Meta-Analysis. JMIR Res Protoc. 2019;8(9):e14759doi: 10.2196/14759.
Hikino, K., Kobayashi, S., Ota, E., Mushiroda, T., & Kobayashi, T. (2019). The Influence of Beta-2 Adrenergic Receptor Gene Polymorphisms on Albuterol Therapy for Patients With Asthma: Protocol for a Systematic Review and Meta-Analysis. JMIR research protocols, 8(9), e14759. https://doi.org/10.2196/14759
Hikino, Keiko, et al. "The Influence of Beta-2 Adrenergic Receptor Gene Polymorphisms on Albuterol Therapy for Patients With Asthma: Protocol for a Systematic Review and Meta-Analysis." JMIR research protocols vol. 8,9 (2019): e14759. doi: https://doi.org/10.2196/14759
Hikino K, Kobayashi S, Ota E, Mushiroda T, Kobayashi T. The Influence of Beta-2 Adrenergic Receptor Gene Polymorphisms on Albuterol Therapy for Patients With Asthma: Protocol for a Systematic Review and Meta-Analysis. JMIR Res Protoc. 2019 Sep 16;8(9):e14759. doi: 10.2196/14759. PMID: 31538939; PMCID: PMC6773362.
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Availability and use of medications by prehospital providers trained to manage medical complications of patients in hazardous materials incidents.

American journal of disaster medicine

Moses Mhayamaguru K, Gaither JB, French RNE, Christopher ND, Waters KE, Jado I, Rice AD, Beskind D, Knotts MC, Ronnebaum J, Smith J, Walter FG.
PMID: 34904706
Am J Disaster Med. 2021 Summer;16(3):215-223. doi: 10.5055/ajdm.2021.0404.

INTRODUCTION: Little is known about prehospital availability and use of medications to treat patients from hazardous materials (hazmat) medical emergencies. The aim of this study was to identify the availability and frequency of use of medications for patients in...

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Moses Mhayamaguru K, Gaither JB, French RNE, et al. Availability and use of medications by prehospital providers trained to manage medical complications of patients in hazardous materials incidents. Am J Disaster Med. 2021;16(3):215-223doi: 10.5055/ajdm.2021.0404.
Moses Mhayamaguru, K., Gaither, J. B., French, R. N. E., Christopher, N. D., Waters, K. E., Jado, I., Rice, A. D., Beskind, D., Knotts, M. C., Ronnebaum, J., Smith, J., & Walter, F. G. (2021). Availability and use of medications by prehospital providers trained to manage medical complications of patients in hazardous materials incidents. American journal of disaster medicine, 16(3), 215-223. https://doi.org/10.5055/ajdm.2021.0404
Moses Mhayamaguru, K, et al. "Availability and use of medications by prehospital providers trained to manage medical complications of patients in hazardous materials incidents." American journal of disaster medicine vol. 16,3 (2021): 215-223. doi: https://doi.org/10.5055/ajdm.2021.0404
Moses Mhayamaguru K, Gaither JB, French RNE, Christopher ND, Waters KE, Jado I, Rice AD, Beskind D, Knotts MC, Ronnebaum J, Smith J, Walter FG. Availability and use of medications by prehospital providers trained to manage medical complications of patients in hazardous materials incidents. Am J Disaster Med. 2021 Summer;16(3):215-223. doi: 10.5055/ajdm.2021.0404. PMID: 34904706.
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Target and Suspect Screening of Pharmaceuticals and Their Transformation Products in the Klip River, South Africa Using Ultra High-Performance Liquid Chromatography-Mass Spectrometry.

Environmental toxicology and chemistry

Madikizela LM, Nuapia YB, Chimuka L, Ncube S, Etale A.
PMID: 34888926
Environ Toxicol Chem. 2021 Dec 09; doi: 10.1002/etc.5265. Epub 2021 Dec 09.

In spite of recent reports on the presence of pharmaceuticals in African water bodies, their prevalence is still not sufficiently quantified. This is because the reports are still few with major focus on a limited number of pharmaceuticals. In...

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Madikizela LM, Nuapia YB, Chimuka L, et al. Target and Suspect Screening of Pharmaceuticals and Their Transformation Products in the Klip River, South Africa Using Ultra High-Performance Liquid Chromatography-Mass Spectrometry. Environ Toxicol Chem. 2021;doi: 10.1002/etc.5265.
Madikizela, L. M., Nuapia, Y. B., Chimuka, L., Ncube, S., & Etale, A. (2021). Target and Suspect Screening of Pharmaceuticals and Their Transformation Products in the Klip River, South Africa Using Ultra High-Performance Liquid Chromatography-Mass Spectrometry. Environmental toxicology and chemistry, . https://doi.org/10.1002/etc.5265
Madikizela, Lawrence M, et al. "Target and Suspect Screening of Pharmaceuticals and Their Transformation Products in the Klip River, South Africa Using Ultra High-Performance Liquid Chromatography-Mass Spectrometry." Environmental toxicology and chemistry vol. (2021). doi: https://doi.org/10.1002/etc.5265
Madikizela LM, Nuapia YB, Chimuka L, Ncube S, Etale A. Target and Suspect Screening of Pharmaceuticals and Their Transformation Products in the Klip River, South Africa Using Ultra High-Performance Liquid Chromatography-Mass Spectrometry. Environ Toxicol Chem. 2021 Dec 09; doi: 10.1002/etc.5265. Epub 2021 Dec 09. PMID: 34888926.
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Showing 13 to 24 of 224 entries