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Showing 13 to 24 of 7888 entries
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Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice.

Cytotechnology

Zhou F, Furuhashi K, Son MJ, Toyozaki M, Yoshizawa F, Miura Y, Yagasaki K.
PMID: 27000262
Cytotechnology. 2017 Jun;69(3):493-502. doi: 10.1007/s10616-016-9965-2. Epub 2016 Mar 21.

Enterolactone (ENL) is formed by the conversion of dietary precursors like strawberry lignans via the gut microbiota. Urinary concentrations of lignan metabolites are reported to be significantly associated with a lower risk of Type 2 diabetes (T2D). In the...

The effects of A2B receptor modulators on vascular endothelial growth factor and nitric oxide axis in chronic cyclosporine nephropathy.

Journal of pharmacology & pharmacotherapeutics

Patel L, Thaker A.
PMID: 26311998
J Pharmacol Pharmacother. 2015 Jul-Sep;6(3):147-53. doi: 10.4103/0976-500X.162014.

INTRODUCTION: To investigate the actions of adenosine A2B receptor modulators on VEGF and NO levels in CsA nephropathy.MATERIALS AND METHODS: Nephropathy was induced by administrating 25 mg/kg (s.c) of CsA for 5 weeks. The VEGF and NO levels were...

Highly sensitive and selective aptasensor for detection of adenosine based on fluorescence resonance energy transfer from carbon dots to nano-graphite.

Journal of colloid and interface science

Wang X, Xu G, Wei F, Ma Y, Ma Y, Song Y, Cen Y, Hu Q.
PMID: 28858655
J Colloid Interface Sci. 2017 Dec 15;508:455-461. doi: 10.1016/j.jcis.2017.07.028. Epub 2017 Jul 10.

In this article, a novel aptasensor was fabricated by modifying carbon dots (CDs) with adenosine aptamer (CDs-aptamer) for sensitive, selective and quantitative detection of adenosine (AD). When nano-graphite (NG) as an energy acceptor was added into the CDs-aptamer (energy...

A 30-year-old female Behçet's disease patient with recurrent pleural and pericardial effusion and elevated adenosine deaminase levels: case report.

Journal of thoracic disease

Choi JY, Kim SH, Kwok SK, Jung JI, Lee KY, Kim TJ, Kang JY.
PMID: 27499994
J Thorac Dis. 2016 Jul;8(7):E547-51. doi: 10.21037/jtd.2016.05.88.

Behçet's disease is a systemic disease which may involve various organs. We describe a case of a patient diagnosed as pleuropericardial involvement of Behçet's disease. A 30-year-old woman visited our clinic presented with left pleuritic chest pain for s...

Lanthanide coordination polymer nanoparticles as a turn-on fluorescence sensing platform for simultaneous detection of histidine and cysteine.

The Analyst

Zhang Z, Wang L, Li G, Ye B.
PMID: 28453013
Analyst. 2017 May 15;142(10):1821-1826. doi: 10.1039/c7an00415j.

In this work, we propose a strategy for the fluorescence assay of histidine (His) and cysteine (Cys) by using lanthanide coordination polymer nanoparticles (Ln-CPN) as a fluorescent probe. The Ln-CPN were prepared by self-assembly of adenosine monophosphate (AMP) with...

Adenosine Deaminase Activity in Chronic Lymphocytic Leukemia and Healthy Subjects.

Iranian journal of cancer prevention

Ghaderi B, Amini S, Maroofi F, Jalali C, Javanmardi M, Roshani D, Abdi M.
PMID: 27703646
Iran J Cancer Prev. 2016 Jun 13;9(3):e5069. doi: 10.17795/ijcp-5069. eCollection 2016 Jun.

BACKGROUND: B cell chronic lymphocytic leukemia is one of the most frequent hematologic malignancies in the world. Cellular surface CD markers and serum Beta-2-microglobulin may be used as a prognostic tool in CLL patients.OBJECTIVES: In the present study we...

Case of angina pectoris at rest and during effort due to coronary spasm and myocardial bridging.

World journal of cardiology

Teragawa H, Fujii Y, Ueda T, Murata D, Nomura S.
PMID: 26131343
World J Cardiol. 2015 Jun 26;7(6):367-72. doi: 10.4330/wjc.v7.i6.367.

We present a case of a 71-year-old male who had chest symptoms at rest and during effort. He had felt chest oppression during effort for 1 year, and his chest symptoms had recently worsened. One month before admission he...

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection).

Medical gas research

Huang L, Applegate PM, Gatling JW, Mangus DB, Zhang J, Applegate RL.
PMID: 25671079
Med Gas Res. 2014 May 20;4:10. doi: 10.1186/2045-9912-4-10. eCollection 2014.

Neurocognitive deficits remain a significant source of morbidity in survivors of cardiac arrest. We conducted a literature review of treatment protocols designed to evaluate neurologic outcome and survival following global cerebral ischemia associated with cardiac arrest. The search was...

Da-bu-yin-wan and qian-zheng-san to neuroprotect the mouse model of Parkinson's disease.

Evidence-based complementary and alternative medicine : eCAM

Gong XG, Sun HM, Zhang Y, Zhang SJ, Gao YS, Feng J, Hu JH, Gai C, Guo ZY, Xu H, Ma L.
PMID: 25610480
Evid Based Complement Alternat Med. 2014;2014:729195. doi: 10.1155/2014/729195. Epub 2014 Dec 24.

Da-Bu-Yin-Wan (DBYW) and Qian-Zheng-San (QZS), two classic traditional Chinese medicinal formulas, were clinically employed to treat Parkinson's disease (PD). Our previous studies demonstrated neuroprotective effects of them on mitochondrial function in PD mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The purpose...

Selective Migration of Subpopulations of Bone Marrow Cells along an SDF-1α and ATP Gradient.

Bone marrow research

Laupheimer M, Skorska A, Große J, Tiedemann G, Steinhoff G, David R, Lux CA.
PMID: 25610653
Bone Marrow Res. 2014;2014:182645. doi: 10.1155/2014/182645. Epub 2014 Dec 31.

Both stem cell chemokine stromal cell-derived factor-1α (SDF-1α) and extracellular nucleotides such as adenosine triphosphate (ATP) are increased in ischemic myocardium. Since ATP has been reported to influence cell migration, we analysed the migratory response of bone marrow cells...

Bedaquiline for the treatment of multidrug-resistant tuberculosis: great promise or disappointment?.

Therapeutic advances in chronic disease

Field SK.
PMID: 26137207
Ther Adv Chronic Dis. 2015 Jul;6(4):170-84. doi: 10.1177/2040622315582325.

Acquired drug resistance by Mycobacterium tuberculosis (MTB) may result in treatment failure and death. Bedaquiline was recently approved for the treatment of multidrug-resistant tuberculosis (MDR-TB). This report examines the available data on this novel drug for the treatment of...

Antiobesity effects of the water-soluble fraction of the ethanol extract of Smilax china L. leaf in 3T3-L1 adipocytes.

Nutrition research and practice

Kang YH, Kim KK, Kim DJ, Choe M.
PMID: 26634049
Nutr Res Pract. 2015 Dec;9(6):606-12. doi: 10.4162/nrp.2015.9.6.606. Epub 2015 Sep 25.

BACKGROUND/OBJECTIVES: Several medicinal properties of Smilax china L. have been studied including antioxidant, anti-inflammatory, and anti-cancer effects. However, the antiobesity activity and mechanism by which the water-soluble fraction of this plant mediates its effects are not clear. In the...

Showing 13 to 24 of 7888 entries