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Showing 13 to 24 of 1376 entries
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Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages.

Li N, Katz S, Dutta B, Benet ZL, Sun J, Fraser ID.
PMID: 28248925
Sci Data. 2017 Mar 01;4:170008. doi: 10.1038/sdata.2017.8.

The mammalian innate immune system senses many bacterial stimuli through the toll-like receptor (TLR) family. Activation of the TLR4 receptor by bacterial lipopolysaccharide (LPS) is the most widely studied TLR pathway due to its central role in host responses...

Massively parallel recordings in macaque motor cortex during an instructed delayed reach-to-grasp task.

Brochier T, Zehl L, Hao Y, Duret M, Sprenger J, Denker M, Grün S, Riehle A.
PMID: 29633986
Sci Data. 2018 Apr 10;5:180055. doi: 10.1038/sdata.2018.55.

We publish two electrophysiological datasets recorded in motor cortex of two macaque monkeys during an instructed delayed reach-to-grasp task, using chronically implanted 10-by-10 Utah electrode arrays. We provide a) raw neural signals (sampled at 30 kHz), b) time stamps...

The Alexandria library, a quantum-chemical database of molecular properties for force field development.

Ghahremanpour MM, van Maaren PJ, van der Spoel D.
PMID: 29633987
Sci Data. 2018 Apr 10;5:180062. doi: 10.1038/sdata.2018.62.

Data quality as well as library size are crucial issues for force field development. In order to predict molecular properties in a large chemical space, the foundation to build force fields on needs to encompass a large variety of...

SuperDRUG2: a one stop resource for approved/marketed drugs.

Siramshetty VB, Eckert OA, Gohlke BO, Goede A, Chen Q, Devarakonda P, Preissner S, Preissner R.
PMID: 29140469
Nucleic Acids Res. 2018 Jan 04;46:D1137-D1143. doi: 10.1093/nar/gkx1088.

Regular monitoring of drug regulatory agency web sites and similar resources for information on new drug approvals and changes to legal status of marketed drugs is impractical. It requires navigation through several resources to find complete information about a...

Longitudinal test-retest neuroimaging data from healthy young adults in southwest China.

Liu W, Wei D, Chen Q, Yang W, Meng J, Wu G, Bi T, Zhang Q, Zuo XN, Qiu J.
PMID: 28195583
Sci Data. 2017 Feb 14;4:170017. doi: 10.1038/sdata.2017.17.

Multimodal magnetic resonance imaging (mMRI) has been widely used to map the structure and function of the human brain, as well as its behavioral associations. However, to date, a large sample with a long-term longitudinal design and a narrow...

ProteomicsDB.

Schmidt T, Samaras P, Frejno M, Gessulat S, Barnert M, Kienegger H, Krcmar H, Schlegl J, Ehrlich HC, Aiche S, Kuster B, Wilhelm M.
PMID: 29106664
Nucleic Acids Res. 2018 Jan 04;46:D1271-D1281. doi: 10.1093/nar/gkx1029.

ProteomicsDB (https://www.ProteomicsDB.org) is a protein-centric in-memory database for the exploration of large collections of quantitative mass spectrometry-based proteomics data. ProteomicsDB was first released in 2014 to enable the interactive exploration of the first draft of the human proteome. To...

High-resolution gridded population datasets for Latin America and the Caribbean in 2010, 2015, and 2020.

Sorichetta A, Hornby GM, Stevens FR, Gaughan AE, Linard C, Tatem AJ.
PMID: 26347245
Sci Data. 2015 Sep 01;2:150045. doi: 10.1038/sdata.2015.45. eCollection 2015.

The Latin America and the Caribbean region is one of the most urbanized regions in the world, with a total population of around 630 million that is expected to increase by 25% by 2050. In this context, detailed and...

X-ray computed tomography library of shark anatomy and lower jaw surface models.

Kamminga P, De Bruin PW, Geleijns J, Brazeau MD.
PMID: 28398352
Sci Data. 2017 Apr 11;4:170047. doi: 10.1038/sdata.2017.47.

The cranial diversity of sharks reflects disparate biomechanical adaptations to feeding. In order to be able to investigate and better understand the ecomorphology of extant shark feeding systems, we created a x-ray computed tomography (CT) library of shark cranial...

Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation.

van der Weyden L, Karp NA, Swiatkowska A, Adams DJ, Speak AO.
PMID: 28895944
Sci Data. 2017 Sep 12;4:170129. doi: 10.1038/sdata.2017.129.

The process of metastasis is a multi-stage cascade with prior studies suggesting that the colonisation of the secondary site is the rate limiting step. This process involves contributions from the tumour cells and also non-tumour intrinsic factors such as...

The public cancer radiology imaging collections of The Cancer Imaging Archive.

Prior F, Smith K, Sharma A, Kirby J, Tarbox L, Clark K, Bennett W, Nolan T, Freymann J.
PMID: 28925987
Sci Data. 2017 Sep 19;4:170124. doi: 10.1038/sdata.2017.124.

The Cancer Imaging Archive (TCIA) is the U.S. National Cancer Institute's repository for cancer imaging and related information. TCIA contains 30.9 million radiology images representing data collected from approximately 37,568 subjects. This data is organized into collections by tumor-type...

A multiscale imaging and modelling dataset of the human inner ear.

Gerber N, Reyes M, Barazzetti L, Kjer HM, Vera S, Stauber M, Mistrik P, Ceresa M, Mangado N, Wimmer W, Stark T, Paulsen RR, Weber S, Caversaccio M, Ballester MAG.
PMID: 28925991
Sci Data. 2017 Sep 19;4:170132. doi: 10.1038/sdata.2017.132.

Understanding the human inner ear anatomy and its internal structures is paramount to advance hearing implant technology. While the emergence of imaging devices allowed researchers to improve understanding of intracochlear structures, the difficulties to collect appropriate data has resulted...

A multimodal MRI dataset of professional chess players.

Li K, Jiang J, Qiu L, Yang X, Huang X, Lui S, Gong Q.
PMID: 26346238
Sci Data. 2015 Sep 01;2:150044. doi: 10.1038/sdata.2015.44. eCollection 2015.

Chess is a good model to study high-level human brain functions such as spatial cognition, memory, planning, learning and problem solving. Recent studies have demonstrated that non-invasive MRI techniques are valuable for researchers to investigate the underlying neural mechanism...

Showing 13 to 24 of 1376 entries