This report concerns a young woman who, after taking a contraceptive preparation orally for three years, developed the Budd-Chiari syndrome as the result of a widespread chronic obliterative process involving the intrahepatic efferent venous system. Her prolonged course, which failed to respond to an end-to-side portacaval shunt procedure, mimicked chronic hepatitis evolving to cirrhosis. Additional noteworthy features were the presence of two small benign hepatic adenomas, observed both at biopsy and at necropsy, a lesion recently recognized as a complication of anovulatory drugs, and widespread hepatic calcifications found at autopsy.
Miyaaki H, Ichikawa T, Taura N, Honda T, Shibata H, Akashi T, Yamamichi S, Turuta S, Soyama A, Hidaka M, Takatsuki M, Okudaira S, Eguchi S, Nakashima O, Kage M, Nakao K.
Am J Case Rep. 2013 Mar 29;14:86-90. doi: 10.12659/AJCR.883864. Print 2013.
PMID: 23826441
