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Ravid M, Robson M, Kedar I. Prolonged colchicine treatment in four patients with amyloidosis. Ann Intern Med. 1977;87(5):568-70doi: 10.7326/0003-4819-87-5-568.
Ravid, M., Robson, M., & Kedar, I. (1977). Prolonged colchicine treatment in four patients with amyloidosis. Annals of internal medicine, 87(5), 568-70. https://doi.org/10.7326/0003-4819-87-5-568
Ravid, M, et al. "Prolonged colchicine treatment in four patients with amyloidosis." Annals of internal medicine vol. 87,5 (1977): 568-70. doi: https://doi.org/10.7326/0003-4819-87-5-568
Ravid M, Robson M, Kedar I. Prolonged colchicine treatment in four patients with amyloidosis. Ann Intern Med. 1977 Nov;87(5):568-70. doi: 10.7326/0003-4819-87-5-568. PMID: 921085.
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Ann Intern Med. 1977 Nov;87(5):568-70. doi: 10.7326/0003-4819-87-5-568.

Prolonged colchicine treatment in four patients with amyloidosis.

Annals of internal medicine

M Ravid, M Robson, I Kedar

PMID: 921085 DOI: 10.7326/0003-4819-87-5-568

Abstract

The natural clinical course of four patients with systemic amyloidosis was favourably altered by continuous colchicine therapy. One patient had primary amyloidosis, and the other three suffered from amyloidosis of familial Mediterranean fever. All had a nephrotic syndrome, and one showed features of intestinal malabsorption. The institution of colchicine therapy was followed by a gradual remission of the nephrotic syndrome, a rise of serum albumin to normal values, a slight improvement of renal function, and regression of the intestinal malabsorption. This pattern has remained steady during an observation period of 30 months.

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