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Intensive Care Med. 1996 Sep;22(9):849-55. doi: 10.1007/BF02044106.

Polyneuropathies in critically ill patients: a prospective evaluation.

Intensive care medicine

K Berek, J Margreiter, J Willeit, A Berek, E Schmutzhard, N J Mutz

Affiliations

  1. Universitätsklinik für Neurologie, Innsbruck, Austria.

PMID: 8905416 DOI: 10.1007/BF02044106

Abstract

OBJECTIVE: To determine the incidence, severity and course of polyneuropathies in patients with sepsis or systemic inflammatory response syndrome combined with multiple organ failure.

DESIGN: Prospective study.

SETTING: Division of Intensive Care Medicine of the Department of Anesthesiology and Intensive Care and Intensive Care Unit of the Department of Neurology, University Hospital Innsbruck, Austria.

PATIENTS: Twenty-two patients between 23 and 77 years old with sepsis or systemic inflammatory response syndrome combined with multiple organ failure fulfilling strict inclusion and exclusion criteria.

INTERVENTIONS: Clinical neurologic examination and electro myography/nerve conduction velocity measurements during the stay on the Intensive Care Unit and 2-3 months later.

MEASUREMENTS AND RESULTS: In 9 of the 22 patients signs of polyneuropathy were found at the initial clinical investigation and in 7 patients at the follow-up investigation. Electrophysiologic investigation revealed signs of polyneuropathy in 18 patients initially and in 11 patients 2-3 months later.

CONCLUSION: In our patient population the frequency of the development of polyneuropathy was high (81.8%). Electrophysiologic investigation is superior to clinical neurologic examination in the detection of polyneuropathies.

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