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Elsevier Science

Radiother Oncol. 1996 Jan;38(1):69-71. doi: 10.1016/0167-8140(95)01670-8.

Probable risk of tumour induction after retro-orbital irradiation for Graves' ophthalmopathy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A Snijders-Keilholz, R J De Keizer, B M Goslings, E W Van Dam, J T Jansen, J J Broerse

Affiliations

  1. Department of Clinical Oncology, University Hospital Leiden, Netherlands.

PMID: 8850428 DOI: 10.1016/0167-8140(95)01670-8

Abstract

Retrobulbar irradiation for Graves' ophthalmopathy is considered as a safe treatment and has recently been recommended as the initial treatment for patients with moderately severe eye problems. However, calculations using risk factors presently known reveal a theoretical risk of radiation-induced cancer of 1.2%. Therefore, the authors suggest that this treatment should be reserved for the elderly patient, for example above the age of 40-50 years.

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