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Ono K, Yamanaga Y, Yamamoto K, et al. Natural killing activities in chronic liver diseases and hepatocellular carcinoma. J Clin Immunol. 1996;16(1):41-5doi: 10.1007/BF01540971.
Ono, K., Yamanaga, Y., Yamamoto, K., Koga, S. I., Nishimura, J., & Nawata, H. (1996). Natural killing activities in chronic liver diseases and hepatocellular carcinoma. Journal of clinical immunology, 16(1), 41-5. https://doi.org/10.1007/BF01540971
Ono, K, et al. "Natural killing activities in chronic liver diseases and hepatocellular carcinoma." Journal of clinical immunology vol. 16,1 (1996): 41-5. doi: https://doi.org/10.1007/BF01540971
Ono K, Yamanaga Y, Yamamoto K, Koga SI, Nishimura J, Nawata H. Natural killing activities in chronic liver diseases and hepatocellular carcinoma. J Clin Immunol. 1996 Jan;16(1):41-5. doi: 10.1007/BF01540971. PMID: 8926284.
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J Clin Immunol. 1996 Jan;16(1):41-5. doi: 10.1007/BF01540971.

Natural killing activities in chronic liver diseases and hepatocellular carcinoma.

Journal of clinical immunology

K Ono, Y Yamanaga, K Yamamoto, S I Koga, J Nishimura, H Nawata

Affiliations

  1. Third Department of Internal Medicine, Kyushu University, Fukuoka, Japan.

PMID: 8926284 DOI: 10.1007/BF01540971

Abstract

Previously we proposed a new analysis of natural killing activity, for comparison, employing an individual effector/target cell ratio according to the peripheral number of effector cells. Using this analysis, we studied natural killing activities in chronic liver diseases and hepatocellular carcinoma (HCC). The activity in chronic persistent hepatitis remained nearly at the level of the nonactivated state, but that was significantly elevated in chronic active hepatitis. The activity in liver cirrhosis (LC) of Child's A or B grade was at the level of a nonactivated or reduced-activity state, while LC patients with impaired general conditions showed significantly elevated activities. In HCC, each of which was accompanied by LC in our cases, the activity appeared to be associated with the progression of HCC. Thus, natural killing activity showed a close relationship with the condition of chronic liver diseases.

References

  1. Jpn J Clin Oncol. 1987 Dec;17(4):327-32 - PubMed
  2. Gastroenterol Jpn. 1987 Jun;22(3):312-21 - PubMed
  3. Lancet. 1972 Apr 1;1(7753):723-6 - PubMed
  4. Am J Clin Pathol. 1988 Feb;89(2):233-7 - PubMed
  5. Gastroenterology. 1990 Aug;99(2):519-24 - PubMed
  6. J Clin Immunol. 1995 Jul;15(4):210-4 - PubMed
  7. J Clin Immunol. 1981 Jan;1(1):51-63 - PubMed
  8. Int J Clin Pharmacol Res. 1987;7(4):301-6 - PubMed
  9. Clin Exp Immunol. 1987 May;68(2):348-56 - PubMed
  10. Hepatology. 1983 May-Jun;3(3):292-6 - PubMed
  11. Nihon Gan Chiryo Gakkai Shi. 1989 Oct 20;24(10):2369-74 - PubMed
  12. Liver. 1991 Apr;11(2):106-13 - PubMed
  13. J Clin Lab Immunol. 1989 Dec;30(4):175-81 - PubMed
  14. Hepatology. 1988 May-Jun;8(3):712-7 - PubMed
  15. Liver. 1986 Aug;6(4):212-20 - PubMed
  16. Hepatogastroenterology. 1990 Oct;37(5):465-8 - PubMed
  17. Korean J Intern Med. 1987 Jul;2(2):221-6 - PubMed
  18. Liver. 1988 Aug;8(4):198-207 - PubMed
  19. Int J Cancer. 1983 Nov 15;32(5):573-5 - PubMed
  20. Dig Dis Sci. 1991 Mar;36(3):299-302 - PubMed

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