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Goldstein DS, Harris AH, Brady JV. Baroreflex sensitivity during operant blood pressure conditioning. Biofeedback Self Regul. 1977;2(2):127-38doi: 10.1007/BF00998663.
Goldstein, D. S., Harris, A. H., & Brady, J. V. (1977). Baroreflex sensitivity during operant blood pressure conditioning. Biofeedback and self-regulation, 2(2), 127-38. https://doi.org/10.1007/BF00998663
Goldstein, D S, et al. "Baroreflex sensitivity during operant blood pressure conditioning." Biofeedback and self-regulation vol. 2,2 (1977): 127-38. doi: https://doi.org/10.1007/BF00998663
Goldstein DS, Harris AH, Brady JV. Baroreflex sensitivity during operant blood pressure conditioning. Biofeedback Self Regul. 1977 Jun;2(2):127-38. doi: 10.1007/BF00998663. PMID: 901850.
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Biofeedback Self Regul. 1977 Jun;2(2):127-38. doi: 10.1007/BF00998663.

Baroreflex sensitivity during operant blood pressure conditioning.

Biofeedback and self-regulation

D S Goldstein, A H Harris, J V Brady

PMID: 901850 DOI: 10.1007/BF00998663

Abstract

Baroreflex sensitivity was measured in baboons operantly conditioned to increase their diastolic blood pressure in daily, 12-hr sessions, by using the extent of increases in interpulse interval per unit of increase in systolic pressure after intravenous phenylephrine injection as an index of baroreflex sensitivity. Following training, baroreflex sensitivity increases averaging 32% were observed before and after the 12-hr conditioning sessions. During the conditioning sessions, however, consistent diastolic blood pressure elevations averaging 17% (14 mmHg) were accompanied by significant decreases in baroreflex sensitivity averaging 44% relative to the increased "before" and "after" sensitivity levels. The results suggest that changes in baroreflex sensitivity participate in operantly conditioned blood pressure changes.

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